J C Roder

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc Natl Acad Sci U S A 1993 20.33
2 A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration. Neuron 1999 3.50
3 Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP. J Neurosci 1997 2.89
4 Chemical induction of mGluR5- and protein synthesis--dependent long-term depression in hippocampal area CA1. J Neurophysiol 2001 2.76
5 Target-effector interaction in the natural killer (NK) cell system. II. The isolation of NK cells and studies on the mechanism of killing. J Immunol 1978 2.29
6 CAKbeta/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampus. Neuron 2001 2.22
7 The beige mutation in the mouse. I. A stem cell predetermined impairment in natural killer cell function. J Immunol 1979 2.11
8 The receptor tyrosine kinase EphB2 regulates NMDA-dependent synaptic function. Neuron 2001 2.02
9 The beige mutation in the mouse. II. Selectivity of the natural killer (NK) cell defect. J Immunol 1979 2.02
10 Src activation in the induction of long-term potentiation in CA1 hippocampal neurons. Science 1998 1.81
11 A new immunodeficiency disorder in humans involving NK cells. Nature 1980 1.78
12 Recognition of myelin-associated glycoprotein by the monoclonal antibody HNK-1. Nature 1984 1.77
13 Regulation of T cell activation, anxiety, and male aggression by RGS2. Proc Natl Acad Sci U S A 2000 1.73
14 Human hybridomas constructed with antigen-specific Epstein-Barr virus-transformed cell lines. Proc Natl Acad Sci U S A 1982 1.73
15 Target-effector interaction in the natural killer cell system: isolation of target structures. Proc Natl Acad Sci U S A 1979 1.71
16 Target--effector interaction in the natural killer cell system. I. Covariance and genetic control of cytolytic and target-cell-binding subpopulations in the mouse. Scand J Immunol 1978 1.70
17 Target-effector interaction in the human and murine natural killer system: specificity and xenogeneic reactivity of the solubilized natural killer-target structure complex and its loss in a somatic cell hybrid. J Exp Med 1979 1.63
18 Requirements for the establishment of high-titered human monoclonal antibodies against tetanus toxoid using the Epstein-Barr virus technique. J Immunol 1981 1.45
19 Low natural in vivo resistance to syngeneic leukaemias in natural killer-deficient mice. Nature 1980 1.42
20 Natural killer cells. Prog Allergy 1981 1.38
21 Reduced fear and aggression and altered serotonin metabolism in Gtf2ird1-targeted mice. Genes Brain Behav 2007 1.37
22 High level functional engraftment of severe combined immunodeficient mice with human peripheral blood lymphocytes following pretreatment with radiation and anti-asialo GM1. J Immunol Methods 1994 1.32
23 Evidence that many of the DISC1 isoforms in C57BL/6J mice are also expressed in 129S6/SvEv mice. Mol Psychiatry 2007 1.32
24 Recombinant myelin-associated glycoprotein confers neural adhesion and neurite outgrowth function. Neuron 1989 1.25
25 Chemiluminescence response of human natural killer cells. I. The relationship between target cell binding, chemiluminescence, and cytolysis. J Exp Med 1982 1.23
26 Oxygen intermediates are triggered early in the cytolytic pathway of human NK cells. Nature 1982 1.22
27 Target-effector interaction in the natural killer cell system. IV. Modulation by cyclic nucleotides. J Immunol 1979 1.20
28 An expanded population of natural killer cells in mice with severe combined immunodeficiency (SCID) lack rearrangement and expression of T cell receptor genes. J Exp Med 1986 1.19
29 Organization of a repetitive human 1.8 kb KpnI sequence localized in the heterochromatin of chromosome 15. Chromosoma 1985 1.19
30 Modulation of NMDA receptors by pituitary adenylate cyclase activating peptide in CA1 neurons requires G alpha q, protein kinase C, and activation of Src. J Neurosci 2005 1.18
31 Target-effector cell interaction in the natural killer cell system. V. Energy requirements, membrane integrity, and the possible involvement of lysosomal enzymes. Immunology 1980 1.15
32 Studies of human natural killer cells. II. Analysis at the single cell level. J Immunol 1982 1.13
33 A functional comparison of tumor cell killing by activated macrophages and natural killer cells. Eur J Immunol 1979 1.12
34 Binding specificities of the sialoadhesin family of I-type lectins. Sialic acid linkage and substructure requirements for binding of myelin-associated glycoprotein, Schwann cell myelin protein, and sialoadhesin. J Biol Chem 1997 1.12
35 The biology of the human natural killer cell. J Clin Immunol 1982 1.11
36 Inducible cellular transformation by a metallothionein-ras hybrid oncogene leads to natural killer cell susceptibility. Nature 1986 1.11
37 Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor. J Neurosci 1996 1.11
38 Suppressor cells in immunosenescence. Fed Proc 1978 1.08
39 Intra-rectal injection of tumour cells: a novel animal model of rectal cancer. Surg Oncol 1992 1.06
40 Human anti-tetanus toxoid monoclonal antibody secreted by EBV-transformed human B cells fused with murine myeloma. Hybridoma 1982 1.04
41 Enhanced dopamine function in DISC1-L100P mutant mice: implications for schizophrenia. Genes Brain Behav 2010 1.04
42 Multiple behavioral anomalies in GluR2 mutant mice exhibiting enhanced LTP. Behav Brain Res 1998 1.03
43 Src potentiation of NMDA receptors in hippocampal and spinal neurons is not mediated by reducing zinc inhibition. J Neurosci 1999 1.03
44 The Lurcher mutation of an alpha-amino-3-hydroxy-5-methyl- 4-isoxazolepropionic acid receptor subunit enhances potency of glutamate and converts an antagonist to an agonist. J Biol Chem 2000 1.01
45 Establishment of a human large cell lung tumor line (QU-DB) with metastatic properties in athymic mice. Cancer 1986 1.01
46 The EBV-hybridoma technique. Methods Enzymol 1986 1.00
47 Natural killer (HNK-1+) cells in Chediak-Higashi patients are present in normal numbers but are abnormal in function and morphology. J Clin Invest 1982 1.00
48 Decreased neuronal Na+, K+ -ATPase activity in Atp1a3 heterozygous mice increases susceptibility to depression-like endophenotypes by chronic variable stress. Genes Brain Behav 2011 1.00
49 Myelin-associated glycoprotein, a cell adhesion molecule of oligodendrocytes, is phosphorylated in brain. Mol Cell Biol 1988 0.99
50 Spatial learning in transgenic mice expressing human presenilin 1 (PS1) transgenes. Neurobiol Aging 2000 0.98
51 Differential splicing of MAG transcripts during CNS and PNS development. Brain Res 1988 0.98
52 T cell activation and cellular cooperation in autoimmune NZB/NZW F hybrid mice. J Immunol 1975 0.98
53 Induction of NMDA receptor-dependent long-term depression in visual cortex does not require metabotropic glutamate receptors. J Neurophysiol 1999 0.96
54 Myelin-associated glycoprotein binding to gangliosides. Structural specificity and functional implications. Ann N Y Acad Sci 1998 0.95
55 Regulation of the immune response in autoimmune NZB/NZW F1 mice. I. The spontaneous generation of splenic suppressor cells. Cell Immunol 1977 0.95
56 Systemic administration of ciliary neurotrophic factor induces cachexia in rodents. J Clin Invest 1994 0.95
57 Forward genetic screen of mouse reveals dominant missense mutation in the P/Q-type voltage-dependent calcium channel, CACNA1A. Genes Brain Behav 2007 0.94
58 Class I (H-2Kb) gene transfection reduces susceptibility of YAC-1 lymphoma targets to natural killer cells. Eur J Immunol 1990 0.94
59 In vitro NK-activity and in vivo resistance to leukemia: studies of beige, beige//nude and wild-type hosts on C57BL background. Int J Cancer 1980 0.93
60 Natural killer cell-mediated lysis involves an hydroxyl radical-dependent step. J Immunol 1985 0.92
61 Oxygen intermediates are required for interferon activation of NK cells. J Interferon Res 1983 0.92
62 Synthesis of soluble myelin-associated glycoprotein in insect and mammalian cells. Gene 1989 0.91
63 Differential involvement of the mu and kappa opioid receptors in spatial learning. Genes Brain Behav 2003 0.91
64 Regulation of the autoimmune plaque-forming cell response to single-strand DNA (sDNA) in vitro. J Immunol 1978 0.91
65 An exoglycosidase-sensitive triggering site on NK cells which is coupled to transmethylation of membrane phospholipids. J Immunol 1985 0.91
66 Spontaneous and induced primary oncogenesis in natural killer (NK)-cell-deficient beige mutant mice. Int J Cancer 1985 0.90
67 Human monoclonal antibodies against Mycobacterium leprae. Infect Immun 1985 0.89
68 The influence of glutamate receptor 2 expression on excitotoxicity in Glur2 null mutant mice. J Neurosci 2001 0.88
69 Adhesion properties of a neuronal epitope recognized by the monoclonal antibody HNK-1. Brain Res 1986 0.87
70 Immunological senescence. I. The role of suppressor cells. Immunology 1978 0.87
71 Glial overexpression of NGF enhances neuropathic pain and adrenergic sprouting into DRG following chronic sciatic constriction in mice. Neurosci Lett 1998 0.87
72 Differential expression of the Leu-7 antigen on human lung tumor cells. Cancer Res 1985 0.86
73 Regulation of myelin-associated glycoprotein binding by sialylated cis-ligands. J Neurochem 1997 0.85
74 A comparative analysis of the phenotypic characteristics of available fusion partners for the construction of human hybridomas. Hybridoma 1983 0.85
75 Over-expression of the DM-20 myelin proteolipid causes central nervous system demyelination in transgenic mice. J Neurochem 1995 0.85
76 Genetic loss of D-amino acid oxidase activity reverses schizophrenia-like phenotypes in mice. Genes Brain Behav 2009 0.85
77 Synaptic modulators Nrxn1 and Nrxn3 are disregulated in a Disc1 mouse model of schizophrenia. Mol Psychiatry 2011 0.85
78 Localization of CNTF immunoreactivity to neurons and astroglia in the CNS. Brain Res Mol Brain Res 1994 0.84
79 A strategy for the production of human monoclonal antibodies reactive with lung tumor cell lines. Cancer Res 1984 0.84
80 Beta N-acetylglucosaminyltransferase V (Mgat5) deficiency reduces the depression-like phenotype in mice. Genes Brain Behav 2007 0.84
81 Conspecific exploration in the T-maze: abnormalities in S100 beta transgenic mice. Physiol Behav 1996 0.84
82 The characterization and cellular distribution of a family of antigens related to myelin associated glycoprotein in the developing nervous system. J Neuroimmunol 1985 0.84
83 Are T-cell lymphomas immunocompetent? Nature 1978 0.83
84 Loss of self-tolerance to single-stranded deoxyribonucleic acid (sDNA) in vitro. J Immunol 1978 0.83
85 Neuronal proteoglycans: biosynthesis and functional interaction with neurons in vitro. J Neurosci 1988 0.83
86 Increased CNTF gene expression in process-bearing astrocytes following injury is augmented by R(-)-deprenyl. J Neurosci Res 1994 0.82
87 Reduction of lower motor neuron degeneration in wobbler mice by N-acetyl-L-cysteine. J Neurosci 1996 0.82
88 Double restriction in NK cell recognition is linked to transmethylation and can be triggered by asparagine-linked oligosaccharides on tumor cells. Cell Immunol 1987 0.82
89 The effect of target cell differentiation on human natural killer cell activity: a specific defect in target cell binding and early activation events. J Immunol 1982 0.82
90 Enhanced lytic susceptibility of Ha-ras transformants after oncogene induction is specific to activated NK cells. J Immunol 1987 0.82
91 Memory and the effect of cold shock in the water maze in S100 beta transgenic mice. Physiol Behav 1996 0.81
92 Accelerated regenerative neurite formation by a neuronal surface epitope reactive with the monoclonal antibody, Leu 7. Neurosci Lett 1985 0.81
93 DNA amplification and tumorigenicity of the human melanoma cell line MeWo. Cancer Res 1985 0.81
94 Transfection of a rat cell line with the v-Ki-ras oncogene is associated with enhanced susceptibility to natural killer cell lysis. J Exp Med 1985 0.81
95 Selective natural killer resistance in a clone of YAC lymphoma cells. Proc Natl Acad Sci U S A 1981 0.81
96 The effect of unphosphorylated and phosphorylated sugar moieties on human and mouse natural killer cell activity: is there selective inhibition at the level of target recognition and lytic acceptor site? Cell Immunol 1983 0.80
97 Human monoclonal antibodies. Mol Cell Biochem 1984 0.80
98 A human hybrid myeloma for production of human monoclonal antibodies. J Immunol 1984 0.80
99 Functional topography of myelin-associated glycoprotein. II. Mapping of domains on molecular fragments. J Neurosci Res 1995 0.80
100 Improved engraftment of human tumours in SCID mice pretreated with radiation and anti-asialo GM1. Anticancer Res 1995 0.80
101 Decreased p21 levels in anti-sense ras transfectants augments NK sensitivity. Mol Immunol 1989 0.80
102 Comparison of cellular immunotherapies and anti-CD3 in the treatment of MCA-38-LD experimental hepatic metastases in C57BL/6 mice. Cancer Res 1990 0.80
103 Mechanisms of human cell-mediated cytotoxicity. II. Correction of the selective defect in natural killing in the Chediak-Higashi syndrome with inducers of intracellular cyclic GMP. J Immunol 1982 0.80
104 DNA amplification and metastasis of the human melanoma cell line MeWo. Cancer Res 1987 0.80
105 Further studies of natural killer cell function in Chediak-Higashi patients. Immunology 1982 0.79
106 Regulation of the immune response in autoimmune NZB/NZW F1 mice. II. Age dependent release of suppressive factors from spleen cells. Immunology 1978 0.79
107 Comparative phenotypic analysis of available human hybridoma fusion partners. Methods Enzymol 1986 0.79
108 High-resolution mapping of GenS3 and B11F7 epitopes on myelin-associated glycoprotein by expression PCR. J Neurochem 1994 0.79
109 Modulated adhesion: a proposal for the role of myelin-associated glycoprotein in myelin wrapping. Clin Chem 1989 0.78
110 EA rosettes using IgG monoclonal antibody-coated erythrocytes: degree of rosette formation correlates with the amount of antibody on the erythrocytes. Scand J Immunol 1981 0.78
111 Effect of vector topology on homologous recombination at the CHO aprt locus. Somat Cell Mol Genet 1993 0.78
112 Induction of malignant lymphoreticular cell line which displays spontaneous killer-cell activity. Int J Cancer 1981 0.78
113 Altered spatial learning and memory in mice lacking the mGluR4 subtype of metabotropic glutamate receptor. Behav Neurosci 1998 0.78
114 In vitro stimulated lymphocytes as a source of human hybridomas. Eur J Immunol 1984 0.78
115 Target-effector interaction in the natural killer (NK) cell system. VI. The influence of age and genotype on NK binding characteristics. Immunology 1980 0.78
116 Murine anti-CD3 monoclonal antibody induces potent cytolytic activity in both T and NK cell populations. Cell Immunol 1989 0.78
117 Comparative analysis of cell surface markers on murine NK cells and CTL target-effector conjugates. Scand J Immunol 1982 0.78
118 Nerve growth factor receptors of human tumors of neural crest origin: characterization of binding site heterogeneity and alteration by theophylline. Cancer Res 1983 0.78
119 Production and characterization of a novel monoclonal antibody inhibitory for murine natural killer cell activity. Immunol Invest 1992 0.78
120 Modulation of K562 cells with sodium butyrate. Association of impaired NK susceptibility with sialic acid and analysis of other parameters. Int J Cancer 1983 0.77
121 A functional and phenotypic comparison of murine natural killer (NK) cells and lymphokine-activated killer (LAK) cells. Int J Cancer 1989 0.77
122 T cell receptor gene rearrangements in cells with natural killer activity in the mouse. Immunol Res 1986 0.77
123 Impaired social memories in 129P2 inbred mice are rescued by reduced Csk expression. Genes Brain Behav 2012 0.77
124 Amelioration of experimental lung metastasis in mice by therapy with anti-CD3 monoclonal antibodies. Cancer Immunol Immunother 1989 0.77
125 Ultrastructural and cytochemical studies of mouse natural killer (NK) cells. Adv Exp Med Biol 1979 0.77
126 Ciliary neurotrophic factor promotes the terminal differentiation of v-myc immortalized sympathoadrenal progenitor cells in vivo. Brain Res Dev Brain Res 1995 0.77
127 Genetic suppression of agrin reduces mania-like behavior in Na+ , K+ -ATPase α3 mutant mice. Genes Brain Behav 2012 0.77
128 Detection of beta-thalassemia using an artificial-restriction fragment length polymorphism generated by the polymerase chain reaction. Nucleic Acids Res 1991 0.76
129 Conservation of functionally important epitopes on myelin associated glycoprotein (MAG). Comp Biochem Physiol B Biochem Mol Biol 1995 0.76
130 The Chediak-Higashi gene in humans. III. Studies on the mechanisms of NK impairment. Clin Exp Immunol 1983 0.75
131 The cooperative effect of the satin and beige mutations in the suppression of NK and CTL activities in mice. Immunogenetics 1984 0.75
132 Cellular distribution of a natural killer cell tumour recognition-related surface antigen in purified human lymphocytes. Immunology 1997 0.75
133 Immunological senescence. II. Normal in vitro colony formation by B cells from old mice. Immunology 1979 0.75
134 Murine lymphocytes with natural killer activity express CTL-derived serine protease genes. Immunology 1989 0.75
135 Rearrangements of chromosomal regions containing ribosomal RNA genes and centromeric heterochromatin in the human melanoma cell line MeWo. Cancer Genet Cytogenet 1986 0.75
136 The NMDA receptor subunit 2B locus (Nmdar2b) maps to the distal end of murine chromosome 6. Mamm Genome 1994 0.75
137 Neurons express ciliary neurotrophic factor mRNA in the early postnatal and adult rat brain. J Neurosci Res 1995 0.75
138 Specific immunoglobulin production and enhanced tumorigenicity following ascites growth of human hybridomas. J Immunol Methods 1985 0.75
139 The inhibitory effect of phenothiazines on NK-mediated cytolysis of tumor cells. Immunopharmacology 1984 0.75
140 The control of autoreactive lymphocytes by a receptor blockade mechanism. Adv Exp Med Biol 1979 0.75
141 Antibody production by human X human hybridomas in serum-free medium. J Immunol Methods 1985 0.75
142 Absence of the GluR2 receptor sensitizes mouse sympathetic neurons to nerve growth factor deprivation. Neurosci Lett 2000 0.75
143 Analysis of transgenic animal pedigrees using the junction-polymerase chain reaction. PCR Methods Appl 1992 0.75
144 Amplified sequences from chromosome 15, including centromeres, nucleolar organizer regions, and centromeric heterochromatin, in homogeneously staining regions in the human melanoma cell line MeWo. Cancer Genet Cytogenet 1985 0.75
145 The production of monoclonal antibodies from human lymphocytes. Immunol Today 1983 0.75
146 Comparative biodistribution and antibody-dependent cellular cytotoxicity of native and heavy chain chimeric antibody. Mol Biother 1991 0.75
147 Physiological effects of CNTF-induced wasting. Cytokine 1996 0.75
148 The in vivo clearance of Ha-ras transformants by natural killer cells. Clin Exp Metastasis 1990 0.75
149 The role of T cell receptors in non-MHC-restricted cytotoxicity. Cell Immunol 1989 0.75
150 Cell interaction in B/W mice: a reversible defect at the T-cell level. Adv Exp Med Biol 1976 0.75
151 Segregation of the NK-sensitive phenotype in human x mouse somatic cell hybrids reveals separate genetic control of recognition and postrecognition determinants. Cell Immunol 1985 0.75
152 Amplified KpnL repetitive DNA sequences in homogeneously staining regions of a human melanoma cell line. J Natl Cancer Inst 1984 0.75
153 A model of target cell recognition and lysis by natural killer cells. Adv Exp Med Biol 1979 0.75
154 Involvement of hydroxyl free radical, but not superoxide, in the cytolytic pathway of natural killer cells. Revision of an earlier hypothesis. Med Biol 1984 0.75
155 NK-mediated reduction of malignancy in human melanoma cells treated with theophylline. Clin Exp Metastasis 1987 0.75
156 The immunocompetence of tumor T cells and their role in generalized immunosuppression and immunostimulation following inoculation of dimethylbenzanthracene-induced leukemia virus in mice. Cell Immunol 1978 0.75
157 Characterization of a murine model (beige) for a natural killer cell immunodeficiency in the Chediak-Higashi syndrome of man. Prog Clin Biol Res 1982 0.75
158 Trichobilharzia ocellata: cercariae masked by antigens of the snail, Lymnaea stagnalis. Exp Parasitol 1977 0.75
159 Comparison of the specific IgM and IgG antibody response in humans induced by antigen (tetanus toxoid) or a polyclonal activator (EBV) in vitro. Int Arch Allergy Appl Immunol 1983 0.75