Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.
|
Proc Natl Acad Sci U S A
|
1993
|
20.33
|
2
|
A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.
|
Neuron
|
1999
|
3.50
|
3
|
Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP.
|
J Neurosci
|
1997
|
2.89
|
4
|
Chemical induction of mGluR5- and protein synthesis--dependent long-term depression in hippocampal area CA1.
|
J Neurophysiol
|
2001
|
2.76
|
5
|
Target-effector interaction in the natural killer (NK) cell system. II. The isolation of NK cells and studies on the mechanism of killing.
|
J Immunol
|
1978
|
2.29
|
6
|
CAKbeta/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampus.
|
Neuron
|
2001
|
2.22
|
7
|
The beige mutation in the mouse. I. A stem cell predetermined impairment in natural killer cell function.
|
J Immunol
|
1979
|
2.11
|
8
|
The receptor tyrosine kinase EphB2 regulates NMDA-dependent synaptic function.
|
Neuron
|
2001
|
2.02
|
9
|
The beige mutation in the mouse. II. Selectivity of the natural killer (NK) cell defect.
|
J Immunol
|
1979
|
2.02
|
10
|
Src activation in the induction of long-term potentiation in CA1 hippocampal neurons.
|
Science
|
1998
|
1.81
|
11
|
A new immunodeficiency disorder in humans involving NK cells.
|
Nature
|
1980
|
1.78
|
12
|
Recognition of myelin-associated glycoprotein by the monoclonal antibody HNK-1.
|
Nature
|
1984
|
1.77
|
13
|
Regulation of T cell activation, anxiety, and male aggression by RGS2.
|
Proc Natl Acad Sci U S A
|
2000
|
1.73
|
14
|
Human hybridomas constructed with antigen-specific Epstein-Barr virus-transformed cell lines.
|
Proc Natl Acad Sci U S A
|
1982
|
1.73
|
15
|
Target-effector interaction in the natural killer cell system: isolation of target structures.
|
Proc Natl Acad Sci U S A
|
1979
|
1.71
|
16
|
Target--effector interaction in the natural killer cell system. I. Covariance and genetic control of cytolytic and target-cell-binding subpopulations in the mouse.
|
Scand J Immunol
|
1978
|
1.70
|
17
|
Target-effector interaction in the human and murine natural killer system: specificity and xenogeneic reactivity of the solubilized natural killer-target structure complex and its loss in a somatic cell hybrid.
|
J Exp Med
|
1979
|
1.63
|
18
|
Requirements for the establishment of high-titered human monoclonal antibodies against tetanus toxoid using the Epstein-Barr virus technique.
|
J Immunol
|
1981
|
1.45
|
19
|
Low natural in vivo resistance to syngeneic leukaemias in natural killer-deficient mice.
|
Nature
|
1980
|
1.42
|
20
|
Natural killer cells.
|
Prog Allergy
|
1981
|
1.38
|
21
|
Reduced fear and aggression and altered serotonin metabolism in Gtf2ird1-targeted mice.
|
Genes Brain Behav
|
2007
|
1.37
|
22
|
High level functional engraftment of severe combined immunodeficient mice with human peripheral blood lymphocytes following pretreatment with radiation and anti-asialo GM1.
|
J Immunol Methods
|
1994
|
1.32
|
23
|
Evidence that many of the DISC1 isoforms in C57BL/6J mice are also expressed in 129S6/SvEv mice.
|
Mol Psychiatry
|
2007
|
1.32
|
24
|
Recombinant myelin-associated glycoprotein confers neural adhesion and neurite outgrowth function.
|
Neuron
|
1989
|
1.25
|
25
|
Chemiluminescence response of human natural killer cells. I. The relationship between target cell binding, chemiluminescence, and cytolysis.
|
J Exp Med
|
1982
|
1.23
|
26
|
Oxygen intermediates are triggered early in the cytolytic pathway of human NK cells.
|
Nature
|
1982
|
1.22
|
27
|
Target-effector interaction in the natural killer cell system. IV. Modulation by cyclic nucleotides.
|
J Immunol
|
1979
|
1.20
|
28
|
An expanded population of natural killer cells in mice with severe combined immunodeficiency (SCID) lack rearrangement and expression of T cell receptor genes.
|
J Exp Med
|
1986
|
1.19
|
29
|
Organization of a repetitive human 1.8 kb KpnI sequence localized in the heterochromatin of chromosome 15.
|
Chromosoma
|
1985
|
1.19
|
30
|
Modulation of NMDA receptors by pituitary adenylate cyclase activating peptide in CA1 neurons requires G alpha q, protein kinase C, and activation of Src.
|
J Neurosci
|
2005
|
1.18
|
31
|
Target-effector cell interaction in the natural killer cell system. V. Energy requirements, membrane integrity, and the possible involvement of lysosomal enzymes.
|
Immunology
|
1980
|
1.15
|
32
|
Studies of human natural killer cells. II. Analysis at the single cell level.
|
J Immunol
|
1982
|
1.13
|
33
|
A functional comparison of tumor cell killing by activated macrophages and natural killer cells.
|
Eur J Immunol
|
1979
|
1.12
|
34
|
Binding specificities of the sialoadhesin family of I-type lectins. Sialic acid linkage and substructure requirements for binding of myelin-associated glycoprotein, Schwann cell myelin protein, and sialoadhesin.
|
J Biol Chem
|
1997
|
1.12
|
35
|
The biology of the human natural killer cell.
|
J Clin Immunol
|
1982
|
1.11
|
36
|
Inducible cellular transformation by a metallothionein-ras hybrid oncogene leads to natural killer cell susceptibility.
|
Nature
|
1986
|
1.11
|
37
|
Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor.
|
J Neurosci
|
1996
|
1.11
|
38
|
Suppressor cells in immunosenescence.
|
Fed Proc
|
1978
|
1.08
|
39
|
Intra-rectal injection of tumour cells: a novel animal model of rectal cancer.
|
Surg Oncol
|
1992
|
1.06
|
40
|
Human anti-tetanus toxoid monoclonal antibody secreted by EBV-transformed human B cells fused with murine myeloma.
|
Hybridoma
|
1982
|
1.04
|
41
|
Enhanced dopamine function in DISC1-L100P mutant mice: implications for schizophrenia.
|
Genes Brain Behav
|
2010
|
1.04
|
42
|
Multiple behavioral anomalies in GluR2 mutant mice exhibiting enhanced LTP.
|
Behav Brain Res
|
1998
|
1.03
|
43
|
Src potentiation of NMDA receptors in hippocampal and spinal neurons is not mediated by reducing zinc inhibition.
|
J Neurosci
|
1999
|
1.03
|
44
|
The Lurcher mutation of an alpha-amino-3-hydroxy-5-methyl- 4-isoxazolepropionic acid receptor subunit enhances potency of glutamate and converts an antagonist to an agonist.
|
J Biol Chem
|
2000
|
1.01
|
45
|
Establishment of a human large cell lung tumor line (QU-DB) with metastatic properties in athymic mice.
|
Cancer
|
1986
|
1.01
|
46
|
The EBV-hybridoma technique.
|
Methods Enzymol
|
1986
|
1.00
|
47
|
Natural killer (HNK-1+) cells in Chediak-Higashi patients are present in normal numbers but are abnormal in function and morphology.
|
J Clin Invest
|
1982
|
1.00
|
48
|
Decreased neuronal Na+, K+ -ATPase activity in Atp1a3 heterozygous mice increases susceptibility to depression-like endophenotypes by chronic variable stress.
|
Genes Brain Behav
|
2011
|
1.00
|
49
|
Myelin-associated glycoprotein, a cell adhesion molecule of oligodendrocytes, is phosphorylated in brain.
|
Mol Cell Biol
|
1988
|
0.99
|
50
|
Spatial learning in transgenic mice expressing human presenilin 1 (PS1) transgenes.
|
Neurobiol Aging
|
2000
|
0.98
|
51
|
Differential splicing of MAG transcripts during CNS and PNS development.
|
Brain Res
|
1988
|
0.98
|
52
|
T cell activation and cellular cooperation in autoimmune NZB/NZW F hybrid mice.
|
J Immunol
|
1975
|
0.98
|
53
|
Induction of NMDA receptor-dependent long-term depression in visual cortex does not require metabotropic glutamate receptors.
|
J Neurophysiol
|
1999
|
0.96
|
54
|
Myelin-associated glycoprotein binding to gangliosides. Structural specificity and functional implications.
|
Ann N Y Acad Sci
|
1998
|
0.95
|
55
|
Regulation of the immune response in autoimmune NZB/NZW F1 mice. I. The spontaneous generation of splenic suppressor cells.
|
Cell Immunol
|
1977
|
0.95
|
56
|
Systemic administration of ciliary neurotrophic factor induces cachexia in rodents.
|
J Clin Invest
|
1994
|
0.95
|
57
|
Forward genetic screen of mouse reveals dominant missense mutation in the P/Q-type voltage-dependent calcium channel, CACNA1A.
|
Genes Brain Behav
|
2007
|
0.94
|
58
|
Class I (H-2Kb) gene transfection reduces susceptibility of YAC-1 lymphoma targets to natural killer cells.
|
Eur J Immunol
|
1990
|
0.94
|
59
|
In vitro NK-activity and in vivo resistance to leukemia: studies of beige, beige//nude and wild-type hosts on C57BL background.
|
Int J Cancer
|
1980
|
0.93
|
60
|
Natural killer cell-mediated lysis involves an hydroxyl radical-dependent step.
|
J Immunol
|
1985
|
0.92
|
61
|
Oxygen intermediates are required for interferon activation of NK cells.
|
J Interferon Res
|
1983
|
0.92
|
62
|
Synthesis of soluble myelin-associated glycoprotein in insect and mammalian cells.
|
Gene
|
1989
|
0.91
|
63
|
Differential involvement of the mu and kappa opioid receptors in spatial learning.
|
Genes Brain Behav
|
2003
|
0.91
|
64
|
Regulation of the autoimmune plaque-forming cell response to single-strand DNA (sDNA) in vitro.
|
J Immunol
|
1978
|
0.91
|
65
|
An exoglycosidase-sensitive triggering site on NK cells which is coupled to transmethylation of membrane phospholipids.
|
J Immunol
|
1985
|
0.91
|
66
|
Spontaneous and induced primary oncogenesis in natural killer (NK)-cell-deficient beige mutant mice.
|
Int J Cancer
|
1985
|
0.90
|
67
|
Human monoclonal antibodies against Mycobacterium leprae.
|
Infect Immun
|
1985
|
0.89
|
68
|
The influence of glutamate receptor 2 expression on excitotoxicity in Glur2 null mutant mice.
|
J Neurosci
|
2001
|
0.88
|
69
|
Adhesion properties of a neuronal epitope recognized by the monoclonal antibody HNK-1.
|
Brain Res
|
1986
|
0.87
|
70
|
Immunological senescence. I. The role of suppressor cells.
|
Immunology
|
1978
|
0.87
|
71
|
Glial overexpression of NGF enhances neuropathic pain and adrenergic sprouting into DRG following chronic sciatic constriction in mice.
|
Neurosci Lett
|
1998
|
0.87
|
72
|
Differential expression of the Leu-7 antigen on human lung tumor cells.
|
Cancer Res
|
1985
|
0.86
|
73
|
Regulation of myelin-associated glycoprotein binding by sialylated cis-ligands.
|
J Neurochem
|
1997
|
0.85
|
74
|
A comparative analysis of the phenotypic characteristics of available fusion partners for the construction of human hybridomas.
|
Hybridoma
|
1983
|
0.85
|
75
|
Over-expression of the DM-20 myelin proteolipid causes central nervous system demyelination in transgenic mice.
|
J Neurochem
|
1995
|
0.85
|
76
|
Genetic loss of D-amino acid oxidase activity reverses schizophrenia-like phenotypes in mice.
|
Genes Brain Behav
|
2009
|
0.85
|
77
|
Synaptic modulators Nrxn1 and Nrxn3 are disregulated in a Disc1 mouse model of schizophrenia.
|
Mol Psychiatry
|
2011
|
0.85
|
78
|
Localization of CNTF immunoreactivity to neurons and astroglia in the CNS.
|
Brain Res Mol Brain Res
|
1994
|
0.84
|
79
|
A strategy for the production of human monoclonal antibodies reactive with lung tumor cell lines.
|
Cancer Res
|
1984
|
0.84
|
80
|
Beta N-acetylglucosaminyltransferase V (Mgat5) deficiency reduces the depression-like phenotype in mice.
|
Genes Brain Behav
|
2007
|
0.84
|
81
|
Conspecific exploration in the T-maze: abnormalities in S100 beta transgenic mice.
|
Physiol Behav
|
1996
|
0.84
|
82
|
The characterization and cellular distribution of a family of antigens related to myelin associated glycoprotein in the developing nervous system.
|
J Neuroimmunol
|
1985
|
0.84
|
83
|
Are T-cell lymphomas immunocompetent?
|
Nature
|
1978
|
0.83
|
84
|
Loss of self-tolerance to single-stranded deoxyribonucleic acid (sDNA) in vitro.
|
J Immunol
|
1978
|
0.83
|
85
|
Neuronal proteoglycans: biosynthesis and functional interaction with neurons in vitro.
|
J Neurosci
|
1988
|
0.83
|
86
|
Increased CNTF gene expression in process-bearing astrocytes following injury is augmented by R(-)-deprenyl.
|
J Neurosci Res
|
1994
|
0.82
|
87
|
Reduction of lower motor neuron degeneration in wobbler mice by N-acetyl-L-cysteine.
|
J Neurosci
|
1996
|
0.82
|
88
|
Double restriction in NK cell recognition is linked to transmethylation and can be triggered by asparagine-linked oligosaccharides on tumor cells.
|
Cell Immunol
|
1987
|
0.82
|
89
|
The effect of target cell differentiation on human natural killer cell activity: a specific defect in target cell binding and early activation events.
|
J Immunol
|
1982
|
0.82
|
90
|
Enhanced lytic susceptibility of Ha-ras transformants after oncogene induction is specific to activated NK cells.
|
J Immunol
|
1987
|
0.82
|
91
|
Memory and the effect of cold shock in the water maze in S100 beta transgenic mice.
|
Physiol Behav
|
1996
|
0.81
|
92
|
Accelerated regenerative neurite formation by a neuronal surface epitope reactive with the monoclonal antibody, Leu 7.
|
Neurosci Lett
|
1985
|
0.81
|
93
|
DNA amplification and tumorigenicity of the human melanoma cell line MeWo.
|
Cancer Res
|
1985
|
0.81
|
94
|
Transfection of a rat cell line with the v-Ki-ras oncogene is associated with enhanced susceptibility to natural killer cell lysis.
|
J Exp Med
|
1985
|
0.81
|
95
|
Selective natural killer resistance in a clone of YAC lymphoma cells.
|
Proc Natl Acad Sci U S A
|
1981
|
0.81
|
96
|
The effect of unphosphorylated and phosphorylated sugar moieties on human and mouse natural killer cell activity: is there selective inhibition at the level of target recognition and lytic acceptor site?
|
Cell Immunol
|
1983
|
0.80
|
97
|
Human monoclonal antibodies.
|
Mol Cell Biochem
|
1984
|
0.80
|
98
|
A human hybrid myeloma for production of human monoclonal antibodies.
|
J Immunol
|
1984
|
0.80
|
99
|
Functional topography of myelin-associated glycoprotein. II. Mapping of domains on molecular fragments.
|
J Neurosci Res
|
1995
|
0.80
|
100
|
Improved engraftment of human tumours in SCID mice pretreated with radiation and anti-asialo GM1.
|
Anticancer Res
|
1995
|
0.80
|
101
|
Decreased p21 levels in anti-sense ras transfectants augments NK sensitivity.
|
Mol Immunol
|
1989
|
0.80
|
102
|
Comparison of cellular immunotherapies and anti-CD3 in the treatment of MCA-38-LD experimental hepatic metastases in C57BL/6 mice.
|
Cancer Res
|
1990
|
0.80
|
103
|
Mechanisms of human cell-mediated cytotoxicity. II. Correction of the selective defect in natural killing in the Chediak-Higashi syndrome with inducers of intracellular cyclic GMP.
|
J Immunol
|
1982
|
0.80
|
104
|
DNA amplification and metastasis of the human melanoma cell line MeWo.
|
Cancer Res
|
1987
|
0.80
|
105
|
Further studies of natural killer cell function in Chediak-Higashi patients.
|
Immunology
|
1982
|
0.79
|
106
|
Regulation of the immune response in autoimmune NZB/NZW F1 mice. II. Age dependent release of suppressive factors from spleen cells.
|
Immunology
|
1978
|
0.79
|
107
|
Comparative phenotypic analysis of available human hybridoma fusion partners.
|
Methods Enzymol
|
1986
|
0.79
|
108
|
High-resolution mapping of GenS3 and B11F7 epitopes on myelin-associated glycoprotein by expression PCR.
|
J Neurochem
|
1994
|
0.79
|
109
|
Modulated adhesion: a proposal for the role of myelin-associated glycoprotein in myelin wrapping.
|
Clin Chem
|
1989
|
0.78
|
110
|
EA rosettes using IgG monoclonal antibody-coated erythrocytes: degree of rosette formation correlates with the amount of antibody on the erythrocytes.
|
Scand J Immunol
|
1981
|
0.78
|
111
|
Effect of vector topology on homologous recombination at the CHO aprt locus.
|
Somat Cell Mol Genet
|
1993
|
0.78
|
112
|
Induction of malignant lymphoreticular cell line which displays spontaneous killer-cell activity.
|
Int J Cancer
|
1981
|
0.78
|
113
|
Altered spatial learning and memory in mice lacking the mGluR4 subtype of metabotropic glutamate receptor.
|
Behav Neurosci
|
1998
|
0.78
|
114
|
In vitro stimulated lymphocytes as a source of human hybridomas.
|
Eur J Immunol
|
1984
|
0.78
|
115
|
Target-effector interaction in the natural killer (NK) cell system. VI. The influence of age and genotype on NK binding characteristics.
|
Immunology
|
1980
|
0.78
|
116
|
Murine anti-CD3 monoclonal antibody induces potent cytolytic activity in both T and NK cell populations.
|
Cell Immunol
|
1989
|
0.78
|
117
|
Comparative analysis of cell surface markers on murine NK cells and CTL target-effector conjugates.
|
Scand J Immunol
|
1982
|
0.78
|
118
|
Nerve growth factor receptors of human tumors of neural crest origin: characterization of binding site heterogeneity and alteration by theophylline.
|
Cancer Res
|
1983
|
0.78
|
119
|
Production and characterization of a novel monoclonal antibody inhibitory for murine natural killer cell activity.
|
Immunol Invest
|
1992
|
0.78
|
120
|
Modulation of K562 cells with sodium butyrate. Association of impaired NK susceptibility with sialic acid and analysis of other parameters.
|
Int J Cancer
|
1983
|
0.77
|
121
|
A functional and phenotypic comparison of murine natural killer (NK) cells and lymphokine-activated killer (LAK) cells.
|
Int J Cancer
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1989
|
0.77
|
122
|
T cell receptor gene rearrangements in cells with natural killer activity in the mouse.
|
Immunol Res
|
1986
|
0.77
|
123
|
Impaired social memories in 129P2 inbred mice are rescued by reduced Csk expression.
|
Genes Brain Behav
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2012
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0.77
|
124
|
Amelioration of experimental lung metastasis in mice by therapy with anti-CD3 monoclonal antibodies.
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Cancer Immunol Immunother
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1989
|
0.77
|
125
|
Ultrastructural and cytochemical studies of mouse natural killer (NK) cells.
|
Adv Exp Med Biol
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1979
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0.77
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126
|
Ciliary neurotrophic factor promotes the terminal differentiation of v-myc immortalized sympathoadrenal progenitor cells in vivo.
|
Brain Res Dev Brain Res
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1995
|
0.77
|
127
|
Genetic suppression of agrin reduces mania-like behavior in Na+ , K+ -ATPase α3 mutant mice.
|
Genes Brain Behav
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2012
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0.77
|
128
|
Detection of beta-thalassemia using an artificial-restriction fragment length polymorphism generated by the polymerase chain reaction.
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Nucleic Acids Res
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1991
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0.76
|
129
|
Conservation of functionally important epitopes on myelin associated glycoprotein (MAG).
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Comp Biochem Physiol B Biochem Mol Biol
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1995
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0.76
|
130
|
The Chediak-Higashi gene in humans. III. Studies on the mechanisms of NK impairment.
|
Clin Exp Immunol
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1983
|
0.75
|
131
|
The cooperative effect of the satin and beige mutations in the suppression of NK and CTL activities in mice.
|
Immunogenetics
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1984
|
0.75
|
132
|
Cellular distribution of a natural killer cell tumour recognition-related surface antigen in purified human lymphocytes.
|
Immunology
|
1997
|
0.75
|
133
|
Immunological senescence. II. Normal in vitro colony formation by B cells from old mice.
|
Immunology
|
1979
|
0.75
|
134
|
Murine lymphocytes with natural killer activity express CTL-derived serine protease genes.
|
Immunology
|
1989
|
0.75
|
135
|
Rearrangements of chromosomal regions containing ribosomal RNA genes and centromeric heterochromatin in the human melanoma cell line MeWo.
|
Cancer Genet Cytogenet
|
1986
|
0.75
|
136
|
The NMDA receptor subunit 2B locus (Nmdar2b) maps to the distal end of murine chromosome 6.
|
Mamm Genome
|
1994
|
0.75
|
137
|
Neurons express ciliary neurotrophic factor mRNA in the early postnatal and adult rat brain.
|
J Neurosci Res
|
1995
|
0.75
|
138
|
Specific immunoglobulin production and enhanced tumorigenicity following ascites growth of human hybridomas.
|
J Immunol Methods
|
1985
|
0.75
|
139
|
The inhibitory effect of phenothiazines on NK-mediated cytolysis of tumor cells.
|
Immunopharmacology
|
1984
|
0.75
|
140
|
The control of autoreactive lymphocytes by a receptor blockade mechanism.
|
Adv Exp Med Biol
|
1979
|
0.75
|
141
|
Antibody production by human X human hybridomas in serum-free medium.
|
J Immunol Methods
|
1985
|
0.75
|
142
|
Absence of the GluR2 receptor sensitizes mouse sympathetic neurons to nerve growth factor deprivation.
|
Neurosci Lett
|
2000
|
0.75
|
143
|
Analysis of transgenic animal pedigrees using the junction-polymerase chain reaction.
|
PCR Methods Appl
|
1992
|
0.75
|
144
|
Amplified sequences from chromosome 15, including centromeres, nucleolar organizer regions, and centromeric heterochromatin, in homogeneously staining regions in the human melanoma cell line MeWo.
|
Cancer Genet Cytogenet
|
1985
|
0.75
|
145
|
The production of monoclonal antibodies from human lymphocytes.
|
Immunol Today
|
1983
|
0.75
|
146
|
Comparative biodistribution and antibody-dependent cellular cytotoxicity of native and heavy chain chimeric antibody.
|
Mol Biother
|
1991
|
0.75
|
147
|
Physiological effects of CNTF-induced wasting.
|
Cytokine
|
1996
|
0.75
|
148
|
The in vivo clearance of Ha-ras transformants by natural killer cells.
|
Clin Exp Metastasis
|
1990
|
0.75
|
149
|
The role of T cell receptors in non-MHC-restricted cytotoxicity.
|
Cell Immunol
|
1989
|
0.75
|
150
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Adv Exp Med Biol
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1976
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Segregation of the NK-sensitive phenotype in human x mouse somatic cell hybrids reveals separate genetic control of recognition and postrecognition determinants.
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1985
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Amplified KpnL repetitive DNA sequences in homogeneously staining regions of a human melanoma cell line.
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J Natl Cancer Inst
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A model of target cell recognition and lysis by natural killer cells.
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1979
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Involvement of hydroxyl free radical, but not superoxide, in the cytolytic pathway of natural killer cells. Revision of an earlier hypothesis.
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1984
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NK-mediated reduction of malignancy in human melanoma cells treated with theophylline.
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The immunocompetence of tumor T cells and their role in generalized immunosuppression and immunostimulation following inoculation of dimethylbenzanthracene-induced leukemia virus in mice.
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Cell Immunol
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1978
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Characterization of a murine model (beige) for a natural killer cell immunodeficiency in the Chediak-Higashi syndrome of man.
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Prog Clin Biol Res
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Comparison of the specific IgM and IgG antibody response in humans induced by antigen (tetanus toxoid) or a polyclonal activator (EBV) in vitro.
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