Published in Tissue Antigens on May 01, 1979
Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis. Cell (1978) 14.82
Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature (1987) 10.21
The number of balanced polymorphisms that can be maintained in a natural population. Genetics (1967) 8.80
Linkage and selection: theoretical analysis of the deterministic two locus random mating model. Genetics (1967) 7.12
Monoclonal antibodies for analysis of the HLA system. Immunol Rev (1979) 6.63
HL-A, immune-response genes, and disease. Lancet (1974) 5.67
p53 mutations in colorectal cancer. Proc Natl Acad Sci U S A (1990) 5.43
Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study. Br J Cancer (2001) 5.36
Use of a monoclonal antibody (W6/32) in structural studies of HLA-A,B,C, antigens. J Immunol (1979) 5.06
A migration matrix model for the study of random genetic drift. Genetics (1968) 4.59
Chromosome 5 allele loss in human colorectal carcinomas. Nature (1987) 4.46
HL-A antigens and disease. Statistical and genetical considerations. Tissue Antigens (1974) 4.41
Monoclonal antibody to cytokeratin for use in routine histopathology. J Clin Pathol (1984) 4.36
Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas. Proc Natl Acad Sci U S A (1999) 4.35
The ABC of APC. Hum Mol Genet (2001) 4.16
Evolutionary significance of the HL-A system. Nature (1972) 4.06
Monoclonal antibodies to epithelium-specific components of the human milk fat globule membrane: production and reaction with cells in culture. Int J Cancer (1981) 3.90
Beta-catenin mutations in cell lines established from human colorectal cancers. Proc Natl Acad Sci U S A (1997) 3.79
Cytotoxic T cells kill influenza virus infected cells but do not distinguish between serologically distinct type A viruses. Nature (1977) 3.67
Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas. Lancet (1992) 3.44
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The Eurasian heartland: a continental perspective on Y-chromosome diversity. Proc Natl Acad Sci U S A (2001) 3.38
Characterization of a monoclonal anti-beta 2-microglobulin antibody and its use in the genetic and biochemical analysis of major histocompatibility antigens. Eur J Immunol (1979) 3.27
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Recombination and integration in Bacillus subtilis transformation: involvement of DNA synthesis. J Mol Biol (1965) 3.21
Evolution of sickle variant gene. Lancet (1979) 3.09
Isolation of glycoproteins from pig lymphocyte plasma membrane using Lens culinaris phytohemagglutinin. Biochem Biophys Res Commun (1972) 3.05
Monoclonal antibody to a human histocompatibility alloantigen, HLA-A2. Nature (1978) 2.93
Evolution and function of the HLA system. Br Med Bull (1978) 2.91
Molecular cloning of the human T-lymphocyte surface CD2 (T11) antigen. Proc Natl Acad Sci U S A (1986) 2.76
The mutation rate and cancer. Proc Natl Acad Sci U S A (1996) 2.73
Preparation and characterization of the plasma membrane of pig lymphocytes. Biochem J (1970) 2.71
Histocompatibility (HL-A) antigens associated with systemic lupus erythematosus. A possible genetic predisposition to disease. N Engl J Med (1971) 2.69
CpG island clones from a deletion encompassing the gene for adenomatous polyposis coli. Proc Natl Acad Sci U S A (1989) 2.66
Protein clinical manifestations of primary tumors of the heart. Am J Med (1972) 2.61
Human genetics: the molecular challenge. Cold Spring Harb Symp Quant Biol (1986) 2.54
cDNA clones coding for the heavy chain of human HLA-DR antigen. Proc Natl Acad Sci U S A (1982) 2.51
Targeting of iodine-123-labelled tumour-associated monoclonal antibodies to ovarian, breast, and gastrointestinal tumours. Lancet (1982) 2.51
The genetic control of HLA-A and B antigens in somatic cell hybrids: requirement for beta2 microglobulin. Tissue Antigens (1978) 2.40
Integration of deoxyribonuclease-treated DNA in bacillus subtilis transformation. J Gen Physiol (1966) 2.32
The beta2-microglobulin gene is on chromosome 15 and not in the HL-A region. Nature (1975) 2.29
The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history. Proc Natl Acad Sci U S A (1998) 2.27
Primary structure of the T3 gamma subunit of the T3/T cell antigen receptor complex deduced from cDNA sequences: evolution of the T3 gamma and delta subunits. EMBO J (1986) 2.25
A marker of early amacrine cell development in rat retina. Brain Res (1985) 2.24
Polyclonal origin of colonic adenomas in an XO/XY patient with FAP. Science (1996) 2.22
Sequence of an HLA-DR alpha-chain cDNA clone and intron-exon organization of the corresponding gene. Nature (1982) 2.18
Orientation of cell-surface antigens in the lipid bilayer of lymphocyte plasma membrane. Nature (1977) 2.18
Diversity in the lipocortin/calpactin family. Cell (1988) 2.11
Activators of protein kinase C down-regulate and phosphorylate the T3/T-cell antigen receptor complex of human T lymphocytes. Proc Natl Acad Sci U S A (1985) 2.10
Protein terminology tangle. Nature (1990) 2.09
Structural studies on gastric mucoproteins: lowering of molecular weight after reduction with 2-mercaptoethanol. Biochem Biophys Res Commun (1970) 2.09
Mutation and expression analysis of the putative prostate tumour-suppressor gene PTEN. Br J Cancer (1998) 2.06
Cellular distrubtion, purification, and molecular nature of human Ia antigens. Scand J Immunol (1977) 2.04
Biosynthesis and molecular nature of the T3 antigen of human T lymphocytes. EMBO J (1983) 2.03
Chromosomal localisation of the human homologues to the oncogenes erbA and B. EMBO J (1984) 2.02
The role of calcium ions in initiating transformation of lymphocytes. Nature (1974) 2.01
A monoclonal antibody that detects HLA-D region antigen in routinely fixed, wax embedded sections of normal and neoplastic lymphoid tissues. J Clin Pathol (1985) 2.00
The structure of the human CD2 gene and its expression in transgenic mice. EMBO J (1988) 2.00
Assignment of the structural gene for the third component of human complement to chromosome 19. Proc Natl Acad Sci U S A (1982) 2.00
Rapid isolation of human chromosome-specific DNA probes from a somatic cell hybrid. Genomics (1990) 1.99
Genetic factors in Hodgkin's disease: association with a disease-susceptibility locus (DSA) in the HL-A region. Natl Cancer Inst Monogr (1973) 1.98
Nomenclature for factors of the HLA system, 1990. Tissue Antigens (1991) 1.98
Studies on gastric mucoproteins. The isolation and characterization of the mucoprotein of the water-soluble mucus from pig cardiac gastric mucosa. Biochem J (1971) 1.98
Chromosomal localization of human cellular homologues of two viral oncogenes. Nature (1982) 1.96
Clinical and molecular features of the hereditary mixed polyposis syndrome. Gastroenterology (1997) 1.96
Six HLA-D region alpha-chain genes on human chromosome 6: polymorphisms and associations of DC alpha-related sequences with DR types. Proc Natl Acad Sci U S A (1984) 1.90
Nomenclature for factors of the HLA system, 2002. Tissue Antigens (2002) 1.89
Biosynthesis and maturation of HLA-DR antigens in vivo. J Biol Chem (1981) 1.86
Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement. Proc Natl Acad Sci U S A (2001) 1.85
Production and characterization of monoclonal antibodies recognizing the alpha-chain subunits of human ia alloantigens. Immunology (1983) 1.85
Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin. Proc Natl Acad Sci U S A (2000) 1.83
Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes. Am J Hum Genet (2001) 1.81
New genetic model for allelism at histocompatibility and other complex loci: polymorphism for control of gene expression. Transplant Proc (1973) 1.80
Failure of programmed cell death and differentiation as causes of tumors: some simple mathematical models. Proc Natl Acad Sci U S A (1995) 1.78
Use of two epithelium-specific monoclonal antibodies for diagnosis of malignancy in serous effusions. Lancet (1982) 1.76
Monoclonal antibodies which recognize different cell types in the rat retina. Nature (1980) 1.76
Preparation and properties of lymphocyte plasma membrane. Contemp Top Mol Immunol (1974) 1.75
The structure and function of gastric mucus. Gut (1972) 1.75
Characterization of gastric mucoproteins isolated by equilibrium density-gradient centrifugation in caesium chloride. Biochem J (1974) 1.74
APC in the regulation of intestinal crypt fission. J Pathol (1998) 1.73
Intestinal trefoil factor controls the expression of the adenomatous polyposis coli-catenin and the E-cadherin-catenin complexes in human colon carcinoma cells. Proc Natl Acad Sci U S A (1998) 1.70
Thy-1 antigen: a ganglion cell specific marker in rodent retina. Neuroscience (1984) 1.67
Relationship between enhanced turnover of phosphatidylinositol and lymphocyte activation by mitogens. Biochem J (1975) 1.67
Genetic testing is important in families with a history suggestive of hereditary non-polyposis colorectal cancer even if the Amsterdam criteria are not fulfilled. Br J Surg (1997) 1.66
SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway. Proc Natl Acad Sci U S A (2001) 1.65
Monoclonal antibodies to Leishmania tropica major: specificities and antigen location. Parasitology (1982) 1.63
Monoclonal antibodies that recognize discrete forms of tubulin. Proc Natl Acad Sci U S A (1982) 1.63
Molecular structure of human histocompatibility antigens: the HLA-C series. Eur J Immunol (1977) 1.61