Published in J Biol Chem on May 23, 1997
Regulated interactions between dynamin and the actin-binding protein cortactin modulate cell shape. J Cell Biol (2000) 3.30
Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex. J Cell Biol (2000) 2.94
Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP. Mol Cell Biol (2004) 2.36
Cortactin branches out: roles in regulating protrusive actin dynamics. Cell Motil Cytoskeleton (2008) 2.26
HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse. Immunity (2006) 2.23
Cortactin signalling and dynamic actin networks. Biochem J (2004) 2.16
Cortactin is a component of clathrin-coated pits and participates in receptor-mediated endocytosis. Mol Cell Biol (2003) 1.92
Cortactin tyrosine phosphorylation requires Rac1 activity and association with the cortical actin cytoskeleton. Mol Biol Cell (2003) 1.90
Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation. Mol Biol Cell (2000) 1.85
A dynamin-cortactin-Arp2/3 complex mediates actin reorganization in growth factor-stimulated cells. Mol Biol Cell (2003) 1.80
The Helicobacter pylori CagA protein induces cortactin dephosphorylation and actin rearrangement by c-Src inactivation. EMBO J (2003) 1.60
Morphological differentiation of oligodendrocytes requires activation of Fyn tyrosine kinase. J Cell Biol (1999) 1.45
Regulation of NADPH oxidase in vascular endothelium: the role of phospholipases, protein kinases, and cytoskeletal proteins. Antioxid Redox Signal (2009) 1.36
Dual regulation of neuronal morphogenesis by a delta-catenin-cortactin complex and Rho. J Cell Biol (2003) 1.35
Actin depolymerization-induced tyrosine phosphorylation of cortactin: the role of Fer kinase. Biochem J (2004) 1.31
Proteolysis of cortactin by calpain regulates membrane protrusion during cell migration. Mol Biol Cell (2005) 1.30
Adenovirus E4 open reading frame 4-induced apoptosis involves dysregulation of Src family kinases. J Cell Biol (2000) 1.28
Recruitment of cortexillin into the cleavage furrow is controlled by Rac1 and IQGAP-related proteins. EMBO J (2001) 1.28
Cortactin phosphorylated by ERK1/2 localizes to sites of dynamic actin regulation and is required for carcinoma lamellipodia persistence. PLoS One (2010) 1.17
Identification of Tyr438 as the major in vitro c-Src phosphorylation site in human gelsolin: a mass spectrometric approach. Protein Sci (1999) 1.16
Interferon alpha inhibits a Src-mediated pathway necessary for Shigella-induced cytoskeletal rearrangements in epithelial cells. J Cell Biol (1998) 1.12
Role of phosphatidylinositol 4,5-bisphosphate in Ras/Rac-induced disruption of the cortactin-actomyosin II complex and malignant transformation. Mol Cell Biol (1998) 1.09
Listeria monocytogenes internalin and E-cadherin: from bench to bedside. Cold Spring Harb Perspect Biol (2009) 1.08
Abp1p and cortactin, new "hand-holds" for actin. J Cell Biol (2001) 1.07
Osteoblast recruitment and bone formation enhanced by cell matrix-associated heparin-binding growth-associated molecule (HB-GAM). J Cell Biol (1998) 1.05
Tyrosine phosphorylation of cofilin at Y68 by v-Src leads to its degradation through ubiquitin-proteasome pathway. Oncogene (2009) 1.02
Activation of the MAP kinase pathway by FGF-1 correlates with cell proliferation induction while activation of the Src pathway correlates with migration. J Cell Biol (1998) 1.02
Interaction of enteropathogenic or enterohemorrhagic Escherichia coli with HeLa cells results in translocation of cortactin to the bacterial adherence site. Infect Immun (2000) 1.02
PC phosphorylation increases the ability of AFAP-110 to cross-link actin filaments. Mol Biol Cell (2002) 0.99
Cortactin as a target for FAK in the regulation of focal adhesion dynamics. PLoS One (2012) 0.97
Dominant expression of 85-kDa form of cortactin in colorectal cancer. J Cancer Res Clin Oncol (2005) 0.95
Cortactin is a functional target of E-cadherin-activated Src family kinases in MCF7 epithelial monolayers. J Biol Chem (2009) 0.95
Tumor-derived mutations in the gene associated with retinoid interferon-induced mortality (GRIM-19) disrupt its anti-signal transducer and activator of transcription 3 (STAT3) activity and promote oncogenesis. J Biol Chem (2013) 0.92
Characterization of the endothelial cell cytoskeleton following HLA class I ligation. PLoS One (2012) 0.91
An essential role for cortactin in the modulation of the potassium channel Kv1.2. Proc Natl Acad Sci U S A (2007) 0.91
Extracellular signal-regulated kinase (ERK) regulates cortactin ubiquitination and degradation in lung epithelial cells. J Biol Chem (2012) 0.89
Cytokine-induced tumor suppressors: a GRIM story. Cytokine (2010) 0.88
Cortactin colocalizes with filopodial actin and accumulates at IgCAM adhesion sites in Aplysia growth cones. J Neurosci Res (2009) 0.88
GRIM-19 inhibits v-Src-induced cell motility by interfering with cytoskeletal restructuring. Oncogene (2009) 0.87
Comparative genome analysis of cortactin and HS1: the significance of the F-actin binding repeat domain. BMC Genomics (2005) 0.87
c-Src-mediated epithelial cell migration and invasion regulated by PDZ binding site. Mol Cell Biol (2007) 0.85
Interactions with actin monomers, actin filaments, and Arp2/3 complex define the roles of WASP family proteins and cortactin in coordinately regulating branched actin networks. J Biol Chem (2014) 0.85
The actin-binding domain of cortactin is dynamic and unstructured and affects lateral and longitudinal contacts in F-actin. Cell Motil Cytoskeleton (2009) 0.84
Src binds cortactin through an SH2 domain cystine-mediated linkage. J Cell Sci (2012) 0.83
Crosstalk between intracellular and extracellular signals regulating interneuron production, migration and integration into the cortex. Front Cell Neurosci (2015) 0.81
Cortactin tyrosine phosphorylation promotes its deacetylation and inhibits cell spreading. PLoS One (2012) 0.81
Cortactin is involved in the entry of Coxiella burnetii into non-phagocytic cells. PLoS One (2012) 0.81
PLC-γ directly binds activated c-Src, which is necessary for carbachol-mediated inhibition of NHE3 activity in Caco-2/BBe cells. Am J Physiol Cell Physiol (2013) 0.80
Abba promotes PDGF-mediated membrane ruffling through activation of the small GTPase Rac1. Biochem Biophys Res Commun (2010) 0.80
Proline-rich region of non-muscle myosin light chain kinase modulates kinase activity and endothelial cytoskeletal dynamics. Microvasc Res (2014) 0.79
Releasing the brakes while hanging on: Cortactin effects on actin-driven motility. Bioarchitecture (2012) 0.78
Further insights into cortactin conformational regulation. Bioarchitecture (2011) 0.78
Thrombopoietin stimulates cortactin translocation to the cytoskeleton independently of tyrosine phosphorylation. Biochem J (2001) 0.78
Tyrosine kinase signalling in breast cancer: modulation of tyrosine kinase signalling in human breast cancer through altered expression of signalling intermediates. Breast Cancer Res (2000) 0.78
The Src family kinase Fyn mediates hyperosmolarity-induced Mrp2 and Bsep retrieval from canalicular membrane. J Biol Chem (2011) 0.77
Synergistic effect of EMS1-shRNA and sorafenib on proliferation, migration, invasion and endocytosis of SMMC-7721. J Mol Histol (2013) 0.77
Cortactin and phagocytosis in isolated Sertoli cells. J Negat Results Biomed (2005) 0.77
Role and structural mechanism of WASP-triggered conformational changes in branched actin filament nucleation by Arp2/3 complex. Proc Natl Acad Sci U S A (2016) 0.77
Involvement of cortactin and phosphotyrosine proteins in cell-cell contact formation in cultured bovine corneal endothelial cells. Histochem Cell Biol (2007) 0.76
Src regulates sequence-dependent beta-2 adrenergic receptor recycling via cortactin phosphorylation. Traffic (2014) 0.76
Cortactin, another player in the Lyn signaling pathway, is over-expressed and alternatively spliced in leukemic cells from patients with B-cell chronic lymphocytic leukemia. Haematologica (2014) 0.76
Hippocampal Cortactin Levels are Reduced Following Spatial Working Memory Formation, an Effect Blocked by Chronic Calpain Inhibition. Brain Sci (2015) 0.75
The Phosphorylation and Distribution of Cortactin Downstream of Integrin α9β1 Affects Cancer Cell Behaviour. Sci Rep (2016) 0.75
Collapsin Response Mediator Protein-1 Regulates Arp2/3-dependent Actin Assembly. J Biol Chem (2015) 0.75
The UCSC Genome Browser Database: 2008 update. Nucleic Acids Res (2007) 23.13
The UCSC Genome Browser Database: update 2009. Nucleic Acids Res (2008) 10.31
A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci U S A (1998) 6.47
Analysis of human transcriptomes. Nat Genet (1999) 6.14
Long-term culture of capillary endothelial cells. Proc Natl Acad Sci U S A (1979) 5.70
Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation. Cancer Res (2001) 4.73
Sexual problems among women and men aged 40-80 y: prevalence and correlates identified in the Global Study of Sexual Attitudes and Behaviors. Int J Impot Res (2005) 4.61
Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature (1996) 4.41
Activation of Arp2/3 complex-mediated actin polymerization by cortactin. Nat Cell Biol (2001) 4.38
The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination. Cell (1995) 4.35
Strong association between malnutrition, inflammation, and atherosclerosis in chronic renal failure. Kidney Int (1999) 4.25
Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination. Proc Natl Acad Sci U S A (1997) 4.13
Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger. Nat Genet (1998) 3.96
DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway. Mol Cell (2000) 3.82
Complications of radiofrequency coagulation of liver tumours. Br J Surg (2002) 3.39
A motivational interviewing intervention to increase fruit and vegetable intake through Black churches: results of the Eat for Life trial. Am J Public Health (2001) 3.37
The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations. Proc Natl Acad Sci U S A (2000) 3.21
Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine. Neuron (2001) 3.10
Aerobic glycolysis during lymphocyte proliferation. Nature (1976) 2.94
One-dimensional electrical contact to a two-dimensional material. Science (2013) 2.87
Meta-analysis of endoscopic submucosal dissection versus endoscopic mucosal resection for tumors of the gastrointestinal tract. Endoscopy (2009) 2.84
Up-regulation of TNF-producing T cells in the bone marrow: a key mechanism by which estrogen deficiency induces bone loss in vivo. Proc Natl Acad Sci U S A (2001) 2.56
Complete genome sequence of the genetically tractable hydrogenotrophic methanogen Methanococcus maripaludis. J Bacteriol (2004) 2.47
Molecular basis of phenotypic heterogeneity in phenylketonuria. N Engl J Med (1991) 2.40
The role of tyrosine phosphorylation of cortactin in the locomotion of endothelial cells. J Biol Chem (1998) 2.39
Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians. Diabetologia (2011) 2.37
TLR engagement prevents transplantation tolerance. Am J Transplant (2006) 2.36
Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function. EMBO J (1995) 2.31
Killed but metabolically active microbes: a new vaccine paradigm for eliciting effector T-cell responses and protective immunity. Nat Med (2005) 2.28
Relation of arterial geometry to luminal narrowing and histologic markers for plaque vulnerability: the remodeling paradox. J Am Coll Cardiol (1998) 2.27
A transforming growth factor beta type I receptor that signals to activate gene expression. Science (1994) 2.26
Maxi-K channels contribute to urinary potassium excretion in the ROMK-deficient mouse model of Type II Bartter's syndrome and in adaptation to a high-K diet. Kidney Int (2006) 2.22
Fibroblast growth factor 2 control of vascular tone. Nat Med (1998) 2.21
Fine structure of vascular endothelium in culture. J Ultrastruct Res (1975) 2.15
Hofstadter's butterfly and the fractal quantum Hall effect in moiré superlattices. Nature (2013) 2.13
Validation of three food frequency questionnaires and 24-hour recalls with serum carotenoid levels in a sample of African-American adults. Am J Epidemiol (2000) 2.11
Spectro-temporal modulation transfer functions and speech intelligibility. J Acoust Soc Am (1999) 2.08
Non-invasive prenatal testing for trisomies 21, 18 and 13: clinical experience from 146,958 pregnancies. Ultrasound Obstet Gynecol (2015) 2.07
Estimation of the cortical functional connectivity with the multimodal integration of high-resolution EEG and fMRI data by directed transfer function. Neuroimage (2005) 2.06
The cellular DNA polymerase alpha-primase is required for papillomavirus DNA replication and associates with the viral E1 helicase. Proc Natl Acad Sci U S A (1994) 2.04
Biological degradation of resin acids in wood chips by wood-inhabiting fungi. Appl Environ Microbiol (1995) 2.04
Therapeutic angiogenesis in patients with advanced coronary artery disease: hype or hope? J Invasive Cardiol (1999) 2.03
The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice. Nat Genet (1995) 2.03
Should formal ophthalmologic evaluation be a preoperative requirement prior to blepharoplasty? Arch Otolaryngol Head Neck Surg (2001) 2.01
Surface display of a parasite antigen in the ciliate Tetrahymena thermophila. Nat Biotechnol (1999) 1.99
Prospective comparison treatment of 595-nm pulsed-dye lasers for virgin port-wine stain. Br J Dermatol (2015) 1.96
Evidence for apoptosis in human atherogenesis and in a rat vascular injury model. Am J Pathol (1995) 1.95
The gastrins: their production and biological activities. Annu Rev Physiol (2001) 1.93
Association between CYP2D6 *10 genotype and survival of breast cancer patients receiving tamoxifen treatment. Ann Oncol (2008) 1.92
Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice. Proc Natl Acad Sci U S A (2000) 1.90
PR39, a peptide regulator of angiogenesis. Nat Med (2000) 1.90
The forearm flap. Clin Plast Surg (1982) 1.90
Viscoelastic response of the rat loading model: implications for studies of strain-adaptive bone formation. Bone (1999) 1.90
Damage to Candida albicans hyphae and pseudohyphae by the myeloperoxidase system and oxidative products of neutrophil metabolism in vitro. J Clin Invest (1980) 1.89
Multiple amylin receptors arise from receptor activity-modifying protein interaction with the calcitonin receptor gene product. Mol Pharmacol (1999) 1.89
Mechanism of quinolone resistance in Staphylococcus aureus. J Infect Chemother (2000) 1.88
Molecularly cloned SHIV-1157ipd3N4: a highly replication- competent, mucosally transmissible R5 simian-human immunodeficiency virus encoding HIV clade C Env. J Virol (2006) 1.87
Cortactin potentiates bone metastasis of breast cancer cells. Cancer Res (2001) 1.85
Reliability and validity of the Panic Disorder Severity Scale: replication and extension. J Psychiatr Res (2001) 1.82
Recovery of mitogenic activity of a growth factor mutant with a nuclear translocation sequence. Science (1990) 1.81
Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: the role of microglia, phagocytosis, and NADPH oxidase. FASEB J (2004) 1.79
Causes of death among people with convulsive epilepsy in rural West China: a prospective study. Neurology (2011) 1.77
Creation and diagnosis of a solid-density plasma with an X-ray free-electron laser. Nature (2012) 1.74
Crystal structure of the thiamin diphosphate-dependent enzyme pyruvate decarboxylase from the yeast Saccharomyces cerevisiae at 2.3 A resolution. J Mol Biol (1996) 1.74
Lowering reperfusion pressure reduces the injury after pulmonary ischemia. Ann Thorac Surg (2000) 1.73
Dietary change through African American churches: baseline results and program description of the eat for life trial. J Cancer Educ (2000) 1.73
Gamma-S crystallin gene (CRYGS) mutation causes dominant progressive cortical cataract in humans. J Med Genet (2005) 1.68
Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67
Paired box 6 (PAX6) regulates glucose metabolism via proinsulin processing mediated by prohormone convertase 1/3 (PC1/3). Diabetologia (2008) 1.66
The RNA structures engaged in replication and transcription of the A59 strain of mouse hepatitis virus. J Gen Virol (2001) 1.66
Expression of a family of complementary-strand transcripts in Epstein-Barr virus-infected cells. Proc Natl Acad Sci U S A (1992) 1.66
What are the basic functions of microfilaments? Insights from studies in budding yeast. J Cell Biol (1994) 1.64
Endothelial regneration. I. Quantitative analysis of initial stages of endothelial regeneration in rat aortic intima. Lab Invest (1978) 1.63
Help-seeking behaviour for sexual problems: the global study of sexual attitudes and behaviors. Int J Clin Pract (2005) 1.63
One third of HLA DQ2 homozygous patients with type 1 diabetes express celiac disease-associated transglutaminase autoantibodies. J Autoimmun (1999) 1.62
Connexin43 null mice reveal that astrocytes express multiple connexins. Brain Res Brain Res Rev (2000) 1.61
The synthesis of sialylated oligosaccharides using a CMP-Neu5Ac synthetase/sialyltransferase fusion. Nat Biotechnol (1998) 1.61
Circadian variation in human ventricular refractoriness. Circulation (1995) 1.61
Retracted Heparin-binding growth factor 1 induces the formation of organoid neovascular structures in vivo. Proc Natl Acad Sci U S A (1989) 1.59
Aggregation-induced emission of 1-methyl-1,2,3,4,5-pentaphenylsilole. Chem Commun (Camb) (2001) 1.59
Amelotin--a Novel Secreted, Ameloblast-specific Protein. J Dent Res (2005) 1.59
Endothelial regeneration. II. Restitution of endothelial continuity. Lab Invest (1979) 1.58
Recombinant fibroblast growth factor-1 promotes intimal hyperplasia and angiogenesis in arteries in vivo. Nature (1993) 1.58
Tissue factor transcription driven by Egr-1 is a critical mechanism of murine pulmonary fibrin deposition in hypoxia. Proc Natl Acad Sci U S A (1998) 1.57
Pharmacologic or genetic manipulation of glutathione S-transferase P1-1 (GSTpi) influences cell proliferation pathways. J Pharmacol Exp Ther (2001) 1.56
Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56
Identification and characterization of three new promoter/operators from Corynebacterium diphtheriae that are regulated by the diphtheria toxin repressor (DtxR) and iron. Infect Immun (1997) 1.55
Molecular characteristics of non-small cell lung cancer. Proc Natl Acad Sci U S A (2001) 1.53
Performance of a modified rabbit model of abdominal aortic aneurysm induced by topical application of porcine elastase: 5-month follow-up study. Eur J Vasc Endovasc Surg (2012) 1.52
Identification of genes overexpressed in head and neck squamous cell carcinoma using a combination of complementary DNA subtraction and microarray analysis. Laryngoscope (2000) 1.51
Identification of a nuclear localization sequence within the structure of the human interleukin-1 alpha precursor. J Biol Chem (1993) 1.51
Myocardial protection in normal and hypoxically stressed neonatal hearts: the superiority of hypocalcemic versus normocalcemic blood cardioplegia. J Thorac Cardiovasc Surg (1996) 1.50
Immediate post-abortal insertion of the frameless GyneFix IUD: initial experience in China. Br J Fam Plann (2000) 1.50
Strong constraints on the rare decays B(s)(0) → μ+ μ- and B0 → μ+ μ-. Phys Rev Lett (2012) 1.50
First observation of the decays B(0) → D(+)K(-)π(+)π(-) and B(-) → D(0)K(-)π(+)π(-). Phys Rev Lett (2012) 1.50