Published in Nucleic Acids Res on July 01, 1997
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Quantitative telomerase enzyme activity determination using droplet digital PCR with single cell resolution. Nucleic Acids Res (2014) 1.04
A novel functional genomics approach identifies mTERT as a suppressor of fibroblast transformation. Nucleic Acids Res (2000) 1.03
Telomerase expression in chickens: constitutive activity in somatic tissues and down-regulation in culture. Proc Natl Acad Sci U S A (1998) 1.02
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Vault poly(ADP-ribose) polymerase is associated with mammalian telomerase and is dispensable for telomerase function and vault structure in vivo. Mol Cell Biol (2004) 0.97
Alternatively spliced telomerase reverse transcriptase variants lacking telomerase activity stimulate cell proliferation. Mol Cell Biol (2012) 0.97
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Effects of a growth hormone-releasing hormone antagonist on telomerase activity, oxidative stress, longevity, and aging in mice. Proc Natl Acad Sci U S A (2010) 0.92
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Telomerase expression is sufficient for chromosomal integrity in cells lacking p53 dependent G1 checkpoint function. J Carcinog (2005) 0.90
Expression of telomeres in astrocytoma WHO grade 2 to 4: TERRA level correlates with telomere length, telomerase activity, and advanced clinical grade. Transl Oncol (2012) 0.89
Analysis of human telomerase activity and function by two color single molecule coincidence fluorescence spectroscopy. J Am Chem Soc (2006) 0.89
Multiple tumor suppressor microRNAs regulate telomerase and TCF7, an important transcriptional regulator of the Wnt pathway. PLoS One (2014) 0.89
A rapid biosensor chip assay for measuring of telomerase activity using surface plasmon resonance. Nucleic Acids Res (2003) 0.88
Human telomerase reverse transcriptase (hTERT) Q169 is essential for telomerase function in vitro and in vivo. PLoS One (2009) 0.88
Identification of a quinoxaline derivative that is a potent telomerase inhibitor leading to cellular senescence of human cancer cells. Biochem J (2003) 0.86
Telomerase-dependent and independent telomere maintenance and its clinical implications in medullary thyroid carcinoma. J Clin Endocrinol Metab (2014) 0.86
Telomere- and telomerase-interacting protein that unfolds telomere G-quadruplex and promotes telomere extension in mammalian cells. Proc Natl Acad Sci U S A (2012) 0.86
New cellular tools reveal complex epithelial-mesenchymal interactions in hepatocarcinogenesis. Br J Cancer (2008) 0.85
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Catalytically active telomerase holoenzyme is assembled in the dense fibrillar component of the nucleolus during S phase. Histochem Cell Biol (2013) 0.85
Zoning of mucosal phenotype, dysplasia, and telomerase activity measured by telomerase repeat assay protocol in Barrett's esophagus. Neoplasia (2004) 0.85
Mechanism of telomerase activation by v-Rel and its contribution to transformation. J Virol (2006) 0.84
An exonuclease I hydrolysis assay for evaluating G-quadruplex stabilization by small molecules. Nucleic Acids Res (2007) 0.84
Silencing of the hTERT gene by shRNA inhibits colon cancer SW480 cell growth in vitro and in vivo. PLoS One (2014) 0.84
Single-molecule real-time detection of telomerase extension activity. Sci Rep (2014) 0.84
Regeneration in pig livers by compensatory hyperplasia induces high levels of telomerase activity. Comp Hepatol (2007) 0.83
Airborne polychlorinated biphenyls (PCBs) reduce telomerase activity and shorten telomere length in immortal human skin keratinocytes (HaCat). Toxicol Lett (2011) 0.83
Regulation of telomerase activity by interferon regulatory factors 4 and 8 in immune cells. Mol Cell Biol (2008) 0.83
Telomerase reverse transcriptase and telomeric-repeat binding factor protein 1 as regulators of telomerase activity in pancreatic cancer cells. Br J Cancer (2001) 0.82
Structural features of mouse telomerase RNA are responsible for the lower activity of mouse telomerase versus human telomerase. Biochem J (2006) 0.82
Rapid upregulation of telomerase activity in human leukemia HL-60 cells treated with clinical doses of the DNA-damaging drug etoposide. Leukemia (2002) 0.82
The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres. PLoS Genet (2015) 0.82
HTERT mRNA partially regulates telomerase activity in gastric adenocarcinoma and adjacent normal gastric mucosa. Dig Dis Sci (2005) 0.81
Impaired telomerase activity hinders proliferation and in vitro transformation of Penaeus monodon lymphoid cells. Cytotechnology (2015) 0.80
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The current role of telomerase in the diagnosis of bladder cancer. Indian J Urol (2009) 0.79
Telomerase activity in human pleural mesothelioma. Thorax (1998) 0.79
Immortalization of neural precursors when telomerase is overexpressed in embryonal carcinomas and stem cells. Mol Biol Cell (2008) 0.79
Downregulation of histone methyltransferase genes SUV39H1 and SUV39H2 increases telomere length in embryonic stem-like cells and embryonic fibroblasts in pigs. J Reprod Dev (2012) 0.79
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Targeting to the endoplasmic reticulum improves the folding of recombinant human telomerase reverse transcriptase. Protein Expr Purif (2007) 0.78
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