Published in Blood on March 01, 2005
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The telomerase reverse transcriptase regulates chromatin state and DNA damage responses. Proc Natl Acad Sci U S A (2005) 2.01
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Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus. Nat Genet (2012) 1.82
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Identification and functional characterization of 2 variant alleles of the telomerase RNA template gene (TERC) in a patient with dyskeratosis congenita. Blood (2005) 1.37
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Estimating human hematopoietic stem cell kinetics using granulocyte telomere lengths. Exp Hematol (2004) 1.33
Functional characterization of telomerase RNA variants found in patients with hematologic disorders. Blood (2004) 1.33
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Synergistic role of Ku80 and poly(ADP-ribose) polymerase in suppressing chromosomal aberrations and liver cancer formation. Cancer Res (2002) 1.20
Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts. Aging Cell (2007) 1.20
FLT3 mutations in early T-cell precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors. PLoS One (2013) 1.17
Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. J Clin Invest (2014) 1.16
Alemtuzumab induces enhanced apoptosis in vitro in B-cells from patients with chronic lymphocytic leukemia by antibody-dependent cellular cytotoxicity. Eur J Pharmacol (2005) 1.16
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Telomeres, telomerase, and hematopoietic stem cell biology. Arch Med Res (2004) 1.10
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Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure. Blood Cells Mol Dis (2006) 1.09
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Imetelstat (GRN163L)--telomerase-based cancer therapy. Recent Results Cancer Res (2010) 1.07
Growth factor independence 1 protects hematopoietic stem cells against apoptosis but also prevents the development of a myeloproliferative-like disease. Stem Cells (2011) 1.07
Recurrent mutation of JAK3 in T-cell prolymphocytic leukemia. Genes Chromosomes Cancer (2014) 1.06
Short telomeres resulting from heritable mutations in the telomerase reverse transcriptase gene predispose for a variety of malignancies. Ann N Y Acad Sci (2009) 1.05
Characterization of primitive hematopoietic cells from patients with dyskeratosis congenita. Blood (2008) 1.04
The IKZF3 (Aiolos) transcription factor is highly upregulated and inversely correlated with clinical progression in chronic lymphocytic leukaemia. Br J Haematol (2008) 1.03
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A novel nonobese diabetic/severe combined immunodeficient xenograft model for chronic lymphocytic leukemia reflects important clinical characteristics of the disease. Cancer Res (2007) 1.00
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