Published in J Clin Invest on August 01, 1997
Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages. Cell Metab (2010) 2.95
Methamphetamine inhibits antigen processing, presentation, and phagocytosis. PLoS Pathog (2008) 1.53
Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase. J Biol Chem (2010) 1.29
Macrophage lipoprotein lipase modulates the development of atherosclerosis but not adiposity. J Lipid Res (2013) 0.85
Adipose triglyceride lipase in immune response, inflammation, and atherosclerosis. Biol Chem (2012) 0.79
CD36 actions in the heart: Lipids, calcium, inflammation, repair and more? Biochim Biophys Acta (2016) 0.78
Biochemical changes in the injured brain. World J Biol Chem (2017) 0.75
Endocytosis. Annu Rev Biochem (1977) 11.42
Metabolic patterns in three types of phagocytizing cells. J Cell Biol (1963) 8.92
Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP). Annu Rev Biochem (1994) 4.98
A stable, radioactive substrate emulsion for assay of lipoprotein lipase. J Lipid Res (1976) 4.38
Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism and atherogenesis. J Lipid Res (1996) 4.01
Lipoprotein lipase. A multifunctional enzyme relevant to common metabolic diseases. N Engl J Med (1989) 3.31
2-Deoxyglucose selectively inhibits Fc and complement receptor-mediated phagocytosis in mouse peritoneal macrophages. I. Description of the inhibitory effect. J Exp Med (1976) 2.80
Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes. J Clin Invest (1995) 2.48
A macrophage receptor that recognizes oxidized low density lipoprotein but not acetylated low density lipoprotein. J Biol Chem (1989) 2.45
Lipoprotein lipase enhances the binding of chylomicrons to low density lipoprotein receptor-related protein. Proc Natl Acad Sci U S A (1991) 2.32
Muscle-specific overexpression of lipoprotein lipase causes a severe myopathy characterized by proliferation of mitochondria and peroxisomes in transgenic mice. J Clin Invest (1995) 2.27
Metabolism of glucose, glutamine, long-chain fatty acids and ketone bodies by murine macrophages. Biochem J (1986) 2.21
In vivo regulation of lipolysis in humans. J Lipid Res (1994) 1.70
Mechanisms by which lipoprotein lipase alters cellular metabolism of lipoprotein(a), low density lipoprotein, and nascent lipoproteins. Roles for low density lipoprotein receptors and heparan sulfate proteoglycans. J Biol Chem (1992) 1.60
Secretion of lipoprotein lipase by macrophages in culture. J Biol Chem (1981) 1.56
Macrophages and smooth muscle cells express lipoprotein lipase in human and rabbit atherosclerotic lesions. Proc Natl Acad Sci U S A (1991) 1.55
Macrophages adhere to glucose-modified basement membrane collagen IV via their scavenger receptors. J Biol Chem (1994) 1.47
Rates of utilization and fates of glucose, glutamine, pyruvate, fatty acids and ketone bodies by mouse macrophages. Biochem J (1987) 1.45
Rates of utilization of glucose, glutamine and oleate and formation of end-products by mouse peritoneal macrophages in culture. Biochem J (1989) 1.43
Lipoprotein lipase is synthesized by macrophage-derived foam cells in human coronary atherosclerotic plaques. J Clin Invest (1992) 1.40
Lipoprotein lipase hydrolysis of retinyl ester. Possible implications for retinoid uptake by cells. J Biol Chem (1994) 1.31
The role of lipoprotein lipase in the metabolism of triglyceride-rich lipoproteins by macrophages. J Biol Chem (1983) 1.30
A fluorescence quenching technique using trypan blue to differentiate between attached and ingested glutaraldehyde-fixed red blood cells in phagocytosing murine macrophages. J Immunol Methods (1983) 1.28
Lipoprotein lipase secretion by human monocyte-derived macrophages. J Clin Invest (1982) 1.26
Increased ATP and creatine phosphate turnover in phagocytosing mouse peritoneal macrophages. J Biol Chem (1979) 1.25
Lipoprotein lipase enhances binding of lipoproteins to heparan sulfate on cell surfaces and extracellular matrix. J Clin Invest (1992) 1.23
Hypoxia induces glucose transporter expression in endothelial cells. Am J Physiol (1992) 1.22
Phagocytosis of unopsonized Pseudomonas aeruginosa by murine macrophages is a two-step process requiring glucose. J Clin Invest (1992) 1.21
Lipoprotein lipase-mediated uptake and degradation of low density lipoproteins by fibroblasts and macrophages. J Clin Invest (1992) 1.20
Lipoprotein lipase increases low density lipoprotein retention by subendothelial cell matrix. J Clin Invest (1992) 1.16
Release of endothelial cell lipoprotein lipase by plasma lipoproteins and free fatty acids. J Biol Chem (1989) 1.16
Localization of lipoprotein lipase mRNA in selected rat tissues. J Lipid Res (1989) 1.13
Interactions of lipoprotein lipase with the active-site inhibitor tetrahydrolipstatin (Orlistat). Eur J Biochem (1994) 1.07
Bovine milk lipoprotein lipase transfers tocopherol to human fibroblasts during triglyceride hydrolysis in vitro. J Clin Invest (1985) 1.03
Substrate utilization during exercise in active people. Am J Clin Nutr (1995) 1.03
Heparan sulphate proteoglycans are involved in the lipoprotein lipase-mediated enhancement of the cellular binding of very low density and low density lipoproteins. Biochem Biophys Res Commun (1992) 1.01
An enzyme-linked immunoassay for lipoprotein lipase. Anal Biochem (1987) 1.00
Lipoprotein lipase gene expression in THP-1 cells. Biochemistry (1989) 0.99
Cellular differences in lipoprotein lipase-mediated uptake of low density lipoproteins. J Biol Chem (1994) 0.99
Adaptations of energy metabolism in the cultivated macrophage. J Exp Med (1973) 0.97
Creatine kinase expression and creatine phosphate accumulation are developmentally regulated during differentiation of mouse and human monocytes. J Exp Med (1984) 0.97
The importance of fuel metabolism to macrophage function. Cell Biochem Funct (1996) 0.91
Spinal cord of the rat contains more lipoprotein lipase than other brain regions. J Lipid Res (1993) 0.90
Transcriptional activation of the lipoprotein lipase gene in macrophages by dexamethasone. Biochemistry (1991) 0.88
Cholesterol accumulation in J774 macrophages induced by triglyceride-rich lipoproteins. Comparison of very low density lipoprotein from subjects with type III, IV, and V hyperlipoproteinemias. Arterioscler Thromb (1991) 0.88
Production and use of an inhibitory monoclonal antibody to human lipoprotein lipase. Biochim Biophys Acta (1986) 0.87
Free fatty acids and exercise. Am J Clin Nutr (1993) 0.85
Lactate transport in macrophages. J Immunol (1993) 0.83
Evidence that cholesteryl ester and triglyceride accumulation in J774 macrophages induced by very low density lipoprotein subfractions occurs by different mechanisms. J Lipid Res (1993) 0.80
Legionnaires' disease bacterium (Legionella pneumophila) multiples intracellularly in human monocytes. J Clin Invest (1980) 12.41
Endocytosis. Annu Rev Biochem (1977) 11.42
Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell (1992) 10.97
Identification of the C3bi receptor of human monocytes and macrophages by using monoclonal antibodies. Proc Natl Acad Sci U S A (1983) 8.57
ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler Thromb (1994) 8.54
Studies of the macrophage complement receptor. Alteration of receptor function upon macrophage activation. J Exp Med (1975) 7.87
Tumor-promoting phorbol esters stimulate C3b and C3b' receptor-mediated phagocytosis in cultured human monocytes. J Exp Med (1982) 7.10
Influence of the Escherichia coli capsule on complement fixation and on phagocytosis and killing by human phagocytes. J Clin Invest (1980) 6.61
Studies on the mechanism of phagocytosis. I. Requirements for circumferential attachment of particle-bound ligands to specific receptors on the macrophage plasma membrane. J Exp Med (1975) 6.36
Characterization of dystrophin in muscle-biopsy specimens from patients with Duchenne's or Becker's muscular dystrophy. N Engl J Med (1988) 5.84
Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance. Proc Natl Acad Sci U S A (2001) 5.48
Effects of immobilized immune complexes on Fc- and complement-receptor function in resident and thioglycollate-elicited mouse peritoneal macrophages. J Exp Med (1979) 5.47
Extracellular cytolysis by activated macrophages and granulocytes. II. Hydrogen peroxide as a mediator of cytotoxicity. J Exp Med (1979) 5.38
Moderate alcohol intake, increased levels of high-density lipoprotein and its subfractions, and decreased risk of myocardial infarction. N Engl J Med (1993) 5.19
AHA Dietary Guidelines: revision 2000: A statement for healthcare professionals from the Nutrition Committee of the American Heart Association. Circulation (2000) 4.80
Activated human monocytes inhibit the intracellular multiplication of Legionnaires' disease bacteria. J Exp Med (1981) 4.08
Receptors for C3b and C3bi promote phagocytosis but not the release of toxic oxygen from human phagocytes. J Exp Med (1983) 3.96
Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils. Nature (1996) 3.92
Characterization of the macrophage receptro for complement and demonstration of its functional independence from the receptor for the Fc portion of immunoglobulin G. J Exp Med (1975) 3.80
Intracellular multiplication of Legionnaires' disease bacteria (Legionella pneumophila) in human monocytes is reversibly inhibited by erythromycin and rifampin. J Clin Invest (1983) 3.79
Upregulation of VCAM-1 and ICAM-1 at atherosclerosis-prone sites on the endothelium in the ApoE-deficient mouse. Arterioscler Thromb Vasc Biol (1998) 3.66
Extracellular cytolysis by activated macrophages and granulocytes. I. Pharmacologic triggering of effector cells and the release of hydrogen peroxide. J Exp Med (1979) 3.61
Segmental response of the macrophage plasma membrane to a phagocytic stimulus. J Exp Med (1974) 3.45
Studies on the mechanism of phagocytosis. II. The interaction of macrophages with anti-immunoglobulin IgG-coated bone marrow-derived lymphocytes. J Exp Med (1976) 3.30
Fibronectin and serum amyloid P component stimulate C3b- and C3bi-mediated phagocytosis in cultured human monocytes. J Exp Med (1983) 3.27
Interaction of the Legionnaires' disease bacterium (Legionella pneumophila) with human phagocytes. I. L. pneumophila resists killing by polymorphonuclear leukocytes, antibody, and complement. J Exp Med (1981) 3.27
Complement receptor type three (CD11b/CD18) of human polymorphonuclear leukocytes recognizes fibrinogen. Proc Natl Acad Sci U S A (1988) 3.25
Human apolipoprotein A-I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse. Proc Natl Acad Sci U S A (1994) 3.24
ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum. Arterioscler Thromb (1994) 3.11
Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice. Science (1990) 3.04
Low-density lipoprotein subclass patterns and risk of myocardial infarction. JAMA (1988) 3.04
Phorbol esters and horseradish peroxidase stimulate pinocytosis and redirect the flow of pinocytosed fluid in macrophages. J Cell Biol (1985) 3.02
The human apolipoprotein C-II gene sequence contains a novel chromosome 19-specific minisatellite in its third intron. J Biol Chem (1987) 2.85
Glycosylated hemoglobins and long-term blood glucose control in diabetes mellitus. J Clin Endocrinol Metab (1977) 2.84
Lipoprotein(a) reduction by N-acetylcysteine. Lancet (1991) 2.81
Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles. J Clin Invest (1992) 2.80
2-Deoxyglucose selectively inhibits Fc and complement receptor-mediated phagocytosis in mouse peritoneal macrophages. I. Description of the inhibitory effect. J Exp Med (1976) 2.80
Cultured endothelial cell monolayers that restrict the transendothelial passage of macromolecules and electrical current. J Cell Biol (1984) 2.73
Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism. Nat Genet (2001) 2.73
Elevating high-density lipoprotein cholesterol in apolipoprotein E-deficient mice remodels advanced atherosclerotic lesions by decreasing macrophage and increasing smooth muscle cell content. Circulation (2001) 2.71
ATP4- permeabilizes the plasma membrane of mouse macrophages to fluorescent dyes. J Biol Chem (1987) 2.69
Human very low density lipoprotein apolipoprotein E isoprotein polymorphism is explained by genetic variation and posttranslational modification. Biochemistry (1981) 2.61
Tubular lysosome morphology and distribution within macrophages depend on the integrity of cytoplasmic microtubules. Proc Natl Acad Sci U S A (1987) 2.61
The mechanisms of reovirus uncoating and gene activation in vivo. Virology (1972) 2.60
Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes. J Clin Invest (1995) 2.48
Yeast mannans inhibit binding and phagocytosis of zymosan by mouse peritoneal macrophages. J Cell Biol (1983) 2.45
Asynchronous synthesis of the complementary strands of the reovirus genome. Proc Natl Acad Sci U S A (1971) 2.42
Isolation and characterization of the human apolipoprotein A-I gene. Proc Natl Acad Sci U S A (1983) 2.42
Protection from lethal gram-positive infection by macrophage scavenger receptor-dependent phagocytosis. J Exp Med (2000) 2.32
Phorbol myristate acetate stimulates microtubule and 10-nm filament extension and lysosome redistribution in mouse macrophages. J Cell Biol (1980) 2.31
Muscle-specific overexpression of lipoprotein lipase causes a severe myopathy characterized by proliferation of mitochondria and peroxisomes in transgenic mice. J Clin Invest (1995) 2.27
Endothelial cell cytosolic free calcium regulates neutrophil migration across monolayers of endothelial cells. J Cell Biol (1993) 2.23
High levels of human apolipoprotein A-I in transgenic mice result in increased plasma levels of small high density lipoprotein (HDL) particles comparable to human HDL3. J Biol Chem (1989) 2.17
Tyrosine phosphorylation of the gamma subunit of Fc gamma receptors, p72syk, and paxillin during Fc receptor-mediated phagocytosis in macrophages. J Biol Chem (1994) 2.17
Mac-1 (CD11b/CD18) is an oligodeoxynucleotide-binding protein. Nat Med (1997) 2.12
Fasting triglycerides, high-density lipoprotein, and risk of myocardial infarction. Circulation (1997) 2.10
Apolipoprotein A-I is required for cholesteryl ester accumulation in steroidogenic cells and for normal adrenal steroid production. J Clin Invest (1996) 2.10
Fura-2 secretion and sequestration in macrophages. A blocker of organic anion transport reveals that these processes occur via a membrane transport system for organic anions. J Immunol (1988) 2.05
Common genetic variation in the promoter of the human apo CIII gene abolishes regulation by insulin and may contribute to hypertriglyceridemia. J Clin Invest (1995) 2.05
Ca(2+)-independent F-actin assembly and disassembly during Fc receptor-mediated phagocytosis in mouse macrophages. J Cell Biol (1991) 2.03
Proposed nomenclature of apoE isoproteins, apoE genotypes, and phenotypes. J Lipid Res (1982) 2.01
Communication between receptors for different ligands on a single cell: ligation of fibronectin receptors induces a reversible alteration in the function of complement receptors on cultured human monocytes. J Cell Biol (1984) 1.99
Phagocytosing macrophages exclude proteins from the zones of contact with opsonized targets. Nature (1984) 1.97
Apolipoprotein B metabolism in subjects with deficiency of apolipoproteins CIII and AI. Evidence that apolipoprotein CIII inhibits catabolism of triglyceride-rich lipoproteins by lipoprotein lipase in vivo. J Clin Invest (1986) 1.96
Fc receptor-mediated phagocytosis occurs in macrophages at exceedingly low cytosolic Ca2+ levels. J Cell Biol (1988) 1.95
Glucose transporters serve as water channels. Proc Natl Acad Sci U S A (1990) 1.95
Inhibition of Fura-2 sequestration and secretion with organic anion transport blockers. Cell Calcium (1990) 1.95
Noninvasive In vivo high-resolution magnetic resonance imaging of atherosclerotic lesions in genetically engineered mice. Circulation (1998) 1.94
Isolation and sequence of a human apolipoprotein CII cDNA clone and its use to isolate and map to human chromosome 19 the gene for apolipoprotein CII. Proc Natl Acad Sci U S A (1984) 1.91
Tyrosine phosphorylation is required for Fc receptor-mediated phagocytosis in mouse macrophages. J Exp Med (1993) 1.91
Fc receptor modulation in mononuclear phagocytes maintained on immobilized immune complexes occurs by diffusion of the receptor molecule. J Exp Med (1983) 1.90
AHA Dietary Guidelines: revision 2000: A statement for healthcare professionals from the Nutrition Committee of the American Heart Association. Stroke (2000) 1.90
Phorbol myristate acetate stimulates pinocytosis and membrane spreading in mouse peritoneal macrophages. J Cell Biol (1980) 1.88
Lipoprotein lipase controls fatty acid entry into adipose tissue, but fat mass is preserved by endogenous synthesis in mice deficient in adipose tissue lipoprotein lipase. Proc Natl Acad Sci U S A (1997) 1.85
Lipoprotein(a) modulation of endothelial cell surface fibrinolysis and its potential role in atherosclerosis. Nature (1989) 1.85
Genetic background determines the extent of atherosclerosis in ApoE-deficient mice. Arterioscler Thromb Vasc Biol (1999) 1.84
An apolipoprotein CIII haplotype protective against hypertriglyceridemia is specified by promoter and 3' untranslated region polymorphisms. Proc Natl Acad Sci U S A (1993) 1.83
Colocalization of F-actin and talin during Fc receptor-mediated phagocytosis in mouse macrophages. J Exp Med (1990) 1.81
An inherited polymorphism in the human apolipoprotein A-I gene locus related to the development of atherosclerosis. Nature (1983) 1.80
The reovirus replicative cycle: conservation of parental RNA and protein. Proc Natl Acad Sci U S A (1970) 1.76
Dendritic location of neural BC1 RNA. Proc Natl Acad Sci U S A (1991) 1.73
Biliary cholesterol excretion: a novel mechanism that regulates dietary cholesterol absorption. Proc Natl Acad Sci U S A (1998) 1.73
The reovirus replicative cycle. Annu Rev Biochem (1976) 1.68
CD11c/CD18 on neutrophils recognizes a domain at the N terminus of the A alpha chain of fibrinogen. Proc Natl Acad Sci U S A (1991) 1.68
Methylation changes in the apolipoprotein AI gene during embryonic development of the mouse. Proc Natl Acad Sci U S A (1991) 1.68
Direct visualization of lipid deposition and reverse lipid transport in a perfused artery : roles of VLDL and HDL. Circ Res (2000) 1.67
Epidemiology and factor analysis of obesity, type II diabetes, hypertension, and dyslipidemia (syndrome X) on the Island of Kosrae, Federated States of Micronesia. Hum Hered (2001) 1.67
Linkage of human apolipoproteins A-I and C-III genes. Nature (1983) 1.66
Isolation and characterization of cDNA clones for human apolipoprotein A-I. Proc Natl Acad Sci U S A (1982) 1.66
Dietary cholesterol increases transcription of the human cholesteryl ester transfer protein gene in transgenic mice. Dependence on natural flanking sequences. J Clin Invest (1992) 1.66
Human apolipoprotein CIII gene expression is regulated by positive and negative cis-acting elements and tissue-specific protein factors. J Biol Chem (1988) 1.64