Published in Adv Exp Med Biol on January 01, 1997
Effect of antibiotics on group A Streptococcus exoprotein production analyzed by two-dimensional gel electrophoresis. Antimicrob Agents Chemother (2005) 1.21
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
The sequence of the human genome. Science (2001) 101.55
The genome sequence of Drosophila melanogaster. Science (2000) 74.32
Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing. J Mol Biol (1980) 61.16
Sequence and organization of the human mitochondrial genome. Nature (1981) 57.39
A whole-genome assembly of Drosophila. Science (2000) 38.48
The DNA sequence of human chromosome 22. Nature (1999) 30.88
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell (1997) 24.57
Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. Nature (2001) 16.89
Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell (1996) 16.73
Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science (1997) 16.09
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell (1998) 13.87
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science (2000) 13.62
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell (1997) 12.83
Orchestrated transcription of key pathways in Arabidopsis by the circadian clock. Science (2000) 12.35
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell (2000) 11.90
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev (1998) 11.86
Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med (2000) 11.35
Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia. Nature (2000) 9.80
Complete genome sequence of an M1 strain of Streptococcus pyogenes. Proc Natl Acad Sci U S A (2001) 9.40
Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol (1999) 8.21
Positional cloning of the gene for multiple endocrine neoplasia-type 1. Science (1997) 7.95
SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene. Cell (1993) 6.95
An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J Biol Chem (1999) 6.88
HOLE: a program for the analysis of the pore dimensions of ion channel structural models. J Mol Graph (1996) 6.48
Chromosome 22-specific low copy repeats and the 22q11.2 deletion syndrome: genomic organization and deletion endpoint analysis. Hum Mol Genet (2000) 6.21
Endonuclease G is an apoptotic DNase when released from mitochondria. Nature (2001) 6.20
DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell (1997) 5.95
The complete nucleotide sequence of the Xenopus laevis mitochondrial genome. J Biol Chem (1985) 5.89
Identification of a point mutation in the voltage-gated sodium channel gene of Kenyan Anopheles gambiae associated with resistance to DDT and pyrethroids. Insect Mol Biol (2000) 5.81
Speech recognition in noise as a function of the number of spectral channels: comparison of acoustic hearing and cochlear implants. J Acoust Soc Am (2001) 5.75
The Ebola virus VP35 protein functions as a type I IFN antagonist. Proc Natl Acad Sci U S A (2000) 5.46
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Proc Natl Acad Sci U S A (2000) 5.38
DNA microarray-mediated transcriptional profiling of the Escherichia coli response to hydrogen peroxide. J Bacteriol (2001) 5.35
Analyses of the cag pathogenicity island of Helicobacter pylori. Mol Microbiol (1998) 5.07
Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J Neurosci (2001) 4.99
Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1). J Exp Med (2001) 4.71
SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element. Proc Natl Acad Sci U S A (1993) 4.61
POWER_SAGE: comparing statistical tests for SAGE experiments. Bioinformatics (2000) 4.56
Noninvasive imaging of in vivo blood flow velocity using optical Doppler tomography. Opt Lett (1997) 4.48
SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types. Cancer Res (1999) 4.23
Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development. J Mol Cell Cardiol (1996) 4.11
Characterization and sequence of the promoter region of the human epidermal growth factor receptor gene. Proc Natl Acad Sci U S A (1985) 4.08
Regulation of the calmodulin-stimulated protein phosphatase, calcineurin. J Biol Chem (1998) 4.02
Treatment of supraventricular tachycardia due to atrioventricular nodal reentry, by radiofrequency catheter ablation of slow-pathway conduction. N Engl J Med (1992) 3.95
Interstitial cells of Cajal mediate cholinergic neurotransmission from enteric motor neurons. J Neurosci (2000) 3.95
Association of the Arabidopsis CTR1 Raf-like kinase with the ETR1 and ERS ethylene receptors. Proc Natl Acad Sci U S A (1998) 3.94
Multiple transcription-factor genes are early targets of phytochrome A signaling. Proc Natl Acad Sci U S A (2001) 3.91
Language comprehension in language-learning impaired children improved with acoustically modified speech. Science (1996) 3.84
The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface. Proc Natl Acad Sci U S A (1998) 3.83
Different pattern of codon recognition by mammalian mitochondrial tRNAs. Proc Natl Acad Sci U S A (1980) 3.74
Self-terminating diffraction gates femtosecond X-ray nanocrystallography measurements. Nat Photonics (2012) 3.68
Structural basis of IAP recognition by Smac/DIABLO. Nature (2001) 3.66
Temporal and rate representations of time-varying signals in the auditory cortex of awake primates. Nat Neurosci (2001) 3.62
Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene. Cell (1986) 3.59
Structural and biochemical basis of apoptotic activation by Smac/DIABLO. Nature (2000) 3.54
Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung. J Clin Invest (1998) 3.51
Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway. Nat Cell Biol (1999) 3.45
Association of Rab25 and Rab11a with the apical recycling system of polarized Madin-Darby canine kidney cells. Mol Biol Cell (1999) 3.45
Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis. Cell (2000) 3.39
Myocyte death in the failing human heart is gender dependent. Circ Res (1999) 3.38
The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation. J Biol Chem (1996) 3.38
Bestrophin, the product of the Best vitelliform macular dystrophy gene (VMD2), localizes to the basolateral plasma membrane of the retinal pigment epithelium. Proc Natl Acad Sci U S A (2000) 3.32
CYP3A variation and the evolution of salt-sensitivity variants. Am J Hum Genet (2004) 3.32
Selective stimulation of bifidobacteria in the human colon by oligofructose and inulin. Gastroenterology (1995) 3.26
Esophageal peristaltic dysfunction in peptic esophagitis. Gastroenterology (1986) 3.16
Schizophrenia after prenatal exposure to the Dutch Hunger Winter of 1944-1945. Arch Gen Psychiatry (1992) 3.10
Assignment of the membrane attachment, DNA binding, and transcriptional activation domains of sterol regulatory element-binding protein-1 (SREBP-1). J Biol Chem (1994) 3.09
Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. I. Identification of the protein and delineation of its target nucleotide sequence. J Biol Chem (1993) 3.04
Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy. J Clin Invest (1997) 2.93
Mobile microbiome: oral bacteria in extra-oral infections and inflammation. J Dent Res (2013) 2.89
The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities. Mol Cell (1998) 2.89
Identification of two KH domain proteins in the alpha-globin mRNP stability complex. EMBO J (1995) 2.87
The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway. J Clin Invest (1999) 2.77
Mitochondrial endonuclease G is important for apoptosis in C. elegans. Nature (2001) 2.76
Cardiolipin provides specificity for targeting of tBid to mitochondria. Nat Cell Biol (2000) 2.74
Radiofrequency catheter ablation of idiopathic left ventricular tachycardia guided by a Purkinje potential. Circulation (1993) 2.71
Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum. Science (2000) 2.70
Three-dimensional structure of Escherichia coli initiator tRNAfMet. Nature (1980) 2.70
Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice. J Clin Invest (2001) 2.67
Development and validation of an ECG algorithm for identifying accessory pathway ablation site in Wolff-Parkinson-White syndrome. J Cardiovasc Electrophysiol (1998) 2.59
Widespread divergence between incipient Anopheles gambiae species revealed by whole genome sequences. Science (2010) 2.58
Glucagon-like peptide-1 increases cAMP but fails to augment contraction in adult rat cardiac myocytes. Circ Res (2001) 2.56
Genetic locus in mice that blocks development of atherosclerosis despite extreme hyperlipidemia. Circ Res (2001) 2.55
Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment. Cell Death Dis (2013) 2.52
Regions of genomic instability on 22q11 and 11q23 as the etiology for the recurrent constitutional t(11;22). Hum Mol Genet (2000) 2.47
Effects of noise and spectral resolution on vowel and consonant recognition: acoustic and electric hearing. J Acoust Soc Am (1998) 2.46
Inflammation and stroke: putative role for cytokines, adhesion molecules and iNOS in brain response to ischemia. Brain Pathol (2000) 2.46
Oligonucleotide inhibition of IL2R alpha mRNA transcription by promoter region collinear triplex formation in lymphocytes. Nucleic Acids Res (1991) 2.46
Comparison of in vivo tissue temperature profile and lesion geometry for radiofrequency ablation with a saline-irrigated electrode versus temperature control in a canine thigh muscle preparation. Circulation (1995) 2.45
Abrogation of the alternative complement pathway by targeted deletion of murine factor B. Proc Natl Acad Sci U S A (1997) 2.44