Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.

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Published in Cell on November 14, 1997

Authors

P Li1, D Nijhawan, I Budihardjo, S M Srinivasula, M Ahmad, E S Alnemri, X Wang

Author Affiliations

1: Howard Hughes Medical Institute, and Department of Biochemistry, University of Texas Southwestern Medical Center at Dallas, 75235, USA.

Associated clinical trials:

Plasma Cytochrome c as Biomarker of Traumatic Injury and Predictor of Outcome | NCT02440373

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