The expression of a novel, epithelium-specific ets transcription factor is restricted to the most differentiated layers in the epidermis.

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Published in Nucleic Acids Res on November 01, 1997

Authors

J M Andreoli1, S I Jang, E Chung, C M Coticchia, P M Steinert, N G Markova

Author Affiliations

1: Laboratory of Skin Biology, NIAMS, NIH, Bethesda, MD 20892-2752, USA.

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Structure and organization of the human transglutaminase 1 gene. J Biol Chem (1992) 1.07

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The NF-kappa B p65 promoter. J Acquir Immune Defic Syndr (1993) 1.07

The human loricrin gene. J Biol Chem (1992) 1.06

Comparative electron-microscope studies on type-III and type-I collagens. Eur J Biochem (1975) 1.06

Coiled-coil trigger motifs in the 1B and 2B rod domain segments are required for the stability of keratin intermediate filaments. Mol Biol Cell (2000) 1.05