Conversion of cysteine to formylglycine: a protein modification in the endoplasmic reticulum.

PubWeight™: 1.13‹?› | Rank: Top 10%

🔗 View Article (PMC 23670)

Published in Proc Natl Acad Sci U S A on October 28, 1997

Authors

T Dierks1, B Schmidt, K von Figura

Author Affiliations

1: Institut für Biochemie und Molekulare Zellbiologie, Abteilung Biochemie II, Universität Göttingen, Gosslerstrasse 12d, 37073 Göttingen, Germany.

Articles citing this

A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme. Proc Natl Acad Sci U S A (2005) 1.45

Sequence determinants directing conversion of cysteine to formylglycine in eukaryotic sulfatases. EMBO J (1999) 1.31

SUMF1 mutations affecting stability and activity of formylglycine generating enzyme predict clinical outcome in multiple sulfatase deficiency. Eur J Hum Genet (2011) 1.04

Molecular testing of 163 patients with Morquio A (Mucopolysaccharidosis IVA) identifies 39 novel GALNS mutations. Mol Genet Metab (2014) 0.95

A novel single-chain antibody fragment for detection of mannose 6-phosphate-containing proteins: application in mucolipidosis type II patients and mice. Am J Pathol (2010) 0.90

Formylglycine, a post-translationally generated residue with unique catalytic capabilities and biotechnology applications. ACS Chem Biol (2015) 0.89

Arylsulfatase G inactivation causes loss of heparan sulfate 3-O-sulfatase activity and mucopolysaccharidosis in mice. Proc Natl Acad Sci U S A (2012) 0.89

Post-Synthetic Regulation of HS Structure: The Yin and Yang of the Sulfs in Cancer. Front Oncol (2014) 0.88

Reconstitution of Formylglycine-generating Enzyme with Copper(II) for Aldehyde Tag Conversion. J Biol Chem (2015) 0.87

Induction of tolerance to human arylsulfatase A in a mouse model of metachromatic leukodystrophy. Mol Med (2007) 0.84

Secretion of phosphomannosyl-deficient arylsulphatase A and cathepsin D from isolated human macrophages. Biochem J (2002) 0.84

Driving forces of protein association: the dimer-octamer equilibrium in arylsulfatase A. Biophys J (2002) 0.81

Aromatase, estrone sulfatase, and 17β-hydroxysteroid dehydrogenase: structure-function studies and inhibitor development. Mol Cell Endocrinol (2010) 0.81

Comparative study of idursulfase beta and idursulfase in vitro and in vivo. J Hum Genet (2016) 0.81

A biochemical and physicochemical comparison of two recombinant enzymes used for enzyme replacement therapies of hunter syndrome. Glycoconj J (2014) 0.80

Arylsulfatase K, a novel lysosomal sulfatase. J Biol Chem (2013) 0.79

An alpha-formylglycine building block for fmoc-based solid-phase peptide synthesis. Org Lett (2006) 0.78

Interaction of arylsulfatase-A (ASA) with its natural sulfoglycolipid substrates: a computational and site-directed mutagenesis study. Glycoconj J (2009) 0.78

Controlling carrageenan structure using a novel formylglycine-dependent sulfatase, an endo-4S-iota-carrageenan sulfatase. Mar Biotechnol (NY) (2012) 0.78

Enzyme-Assisted Preparation of Furcellaran-Like κ-/β-Carrageenan. Mar Biotechnol (NY) (2015) 0.76

Phylogeny of Algal Sequences Encoding Carbohydrate Sulfotransferases, Formylglycine-Dependent Sulfatases, and Putative Sulfatase Modifying Factors. Front Plant Sci (2015) 0.75

Genome Analysis of Planctomycetes Inhabiting Blades of the Red Alga Porphyra umbilicalis. PLoS One (2016) 0.75

Articles cited by this

Preparation of microsomal membranes for cotranslational protein translocation. Methods Enzymol (1983) 6.94

Protein transport across the eukaryotic endoplasmic reticulum and bacterial inner membranes. Annu Rev Biochem (1996) 4.25

Selenocysteine. Annu Rev Biochem (1996) 4.08

Determination of the distance between the oligosaccharyltransferase active site and the endoplasmic reticulum membrane. J Biol Chem (1993) 3.02

Cloning and expression of human arylsulfatase A. J Biol Chem (1989) 2.55

A novel amino acid modification in sulfatases that is defective in multiple sulfatase deficiency. Cell (1995) 2.38

A cluster of sulfatase genes on Xp22.3: mutations in chondrodysplasia punctata (CDPX) and implications for warfarin embryopathy. Cell (1995) 1.95

Vectors for efficient expression in mammalian fibroblastoid, myeloid and lymphoid cells via transfection or infection. Gene (1988) 1.78

Structure of a human lysosomal sulfatase. Structure (1997) 1.57

Transcription of full-length and truncated mRNA transcripts to study protein translocation across the endoplasmic reticulum. Methods Cell Biol (1991) 1.40

A microsomal ATP-binding protein involved in efficient protein transport into the mammalian endoplasmic reticulum. EMBO J (1996) 1.38

Neither type of mannose 6-phosphate receptor is sufficient for targeting of lysosomal enzymes along intracellular routes. J Cell Biol (1996) 1.36

An inducible arylsulfatase of Volvox carteri with properties suitable for a reporter-gene system. Purification, characterization and molecular cloning. Eur J Biochem (1994) 1.16

Snapshots of membrane-translocating proteins. Trends Cell Biol (1996) 1.12

The evolutionary conservation of a novel protein modification, the conversion of cysteine to serinesemialdehyde in arylsulfatase from Volvox carteri. Eur J Biochem (1996) 1.05

Multiple sulfatase deficiency: catalytically inactive sulfatases are expressed from retrovirally introduced sulfatase cDNAs. Proc Natl Acad Sci U S A (1992) 1.00

Overexpression of N-acetylgalactosamine-4-sulphatase induces a multiple sulphatase deficiency in mucopolysaccharidosis-type-VI fibroblasts. Biochem J (1993) 0.94

Structural requirements for transport of preprocecropinA and related presecretory proteins into mammalian microsomes. J Biol Chem (1992) 0.93

Glycosylation and phosphorylation of arylsulfatase A. J Biol Chem (1994) 0.89

Luciferase assembly after transport into mammalian microsomes involves molecular chaperones and peptidyl-prolyl cis/trans-isomerases. J Biol Chem (1996) 0.81

Articles by these authors

Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice. Nature (2000) 6.34

Lipid mediator class switching during acute inflammation: signals in resolution. Nat Immunol (2001) 5.87

Lysosomal enzymes and their receptors. Annu Rev Biochem (1986) 5.09

Searching MEDLINE for randomized clinical trials involving care of the newborn. Pediatrics (1989) 4.79

Circulating nucleic acids (CNAs) and cancer--a survey. Biochim Biophys Acta (2006) 4.60

mu1A-adaptin-deficient mice: lethality, loss of AP-1 binding and rerouting of mannose 6-phosphate receptors. EMBO J (2000) 4.06

Intracellular receptor sorting during endocytosis: comparative immunoelectron microscopy of multiple receptors in rat liver. Cell (1984) 3.96

Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice. Proc Natl Acad Sci U S A (1998) 3.60

Carbohydrate-deficient glycoprotein syndrome type Ib. Phosphomannose isomerase deficiency and mannose therapy. J Clin Invest (1998) 3.32

Possible pathways for lysosomal enzyme delivery. J Cell Biol (1985) 3.25

Recent observations on the serology of syphilis. Br J Vener Dis (1980) 2.90

IUSTI: 2008 European Guidelines on the Management of Syphilis. Int J STD AIDS (2009) 2.85

Requirement of a membrane potential for the posttranslational transfer of proteins into mitochondria. Eur J Biochem (1982) 2.71

Molecular basis of different forms of metachromatic leukodystrophy. N Engl J Med (1991) 2.69

Molecular evidence for transmission of hepatitis G virus by blood transfusion. Lancet (1996) 2.57

Mitochondrial protein import: identification of processing peptidase and of PEP, a processing enhancing protein. Cell (1988) 2.57

Cloning and expression of human arylsulfatase A. J Biol Chem (1989) 2.55

Enzymatic phosphorylation of lysosomal enzymes in the presence of UDP-N-acetylglucosamine. Absence of the activity in I-cell fibroblasts. Biochem Biophys Res Commun (1981) 2.53

Early prediction of poor outcome in extremely low birth weight infants by classification tree analysis. J Pediatr (2006) 2.49

Arylsulfatase A pseudodeficiency: loss of a polyadenylylation signal and N-glycosylation site. Proc Natl Acad Sci U S A (1989) 2.47

A novel amino acid modification in sulfatases that is defective in multiple sulfatase deficiency. Cell (1995) 2.38

Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells. EMBO J (1995) 2.38

Differences in the endosomal distributions of the two mannose 6-phosphate receptors. J Cell Biol (1993) 2.25

Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons. J Neurosci (2000) 2.21

Transport into mitochondria and intramitochondrial sorting of the Fe/S protein of ubiquinol-cytochrome c reductase. Cell (1986) 2.21

Role of microglia and host prion protein in neurotoxicity of a prion protein fragment. Nature (1996) 2.20

Antibody to mannose 6-phosphate specific receptor induces receptor deficiency in human fibroblasts. EMBO J (1984) 2.11

Attosecond spectroscopy in condensed matter. Nature (2007) 2.10

A di-leucine-based motif in the cytoplasmic tail of LIMP-II and tyrosinase mediates selective binding of AP-3. EMBO J (1998) 2.09

Structure of the arylsulfatase A gene. Eur J Biochem (1990) 2.07

Lysosomal acid phosphatase is transported to lysosomes via the cell surface. EMBO J (1989) 2.04

Quality of care of VLBW neonates: relationship between unit volume and outcome is different between metropolitan and rural regions. Acta Paediatr (2008) 2.04

A PC program for estimating organ dose and effective dose values in computed tomography. Eur Radiol (1999) 2.03

Human lysosomal acid phosphatase is transported as a transmembrane protein to lysosomes in transfected baby hamster kidney cells. EMBO J (1988) 1.99

Synthesis of phosphorylated recognition marker in lysosomal enzymes is located in the cis part of Golgi apparatus. J Biol Chem (1982) 1.98

Transition metals, ferritin, glutathione, and ascorbic acid in parkinsonian brains. J Neurochem (1989) 1.94

Purification and some properties of five endo-1,4-beta-D-xylanases and a beta-D-xylosidase produced by a strain of Aspergillus niger. Can J Biochem (1979) 1.93

Targeting of a lysosomal membrane protein: a tyrosine-containing endocytosis signal in the cytoplasmic tail of lysosomal acid phosphatase is necessary and sufficient for targeting to lysosomes. EMBO J (1990) 1.93

Quantitative aspects of pinocytosis and the intracellular fate of N-acetyl-alpha-D-glucosaminidase in Sanfilippo B fibroblasts. J Clin Invest (1974) 1.92

Detection of "deleted" mitochondrial genomes in cytochrome-c oxidase-deficient muscle fibers of a patient with Kearns-Sayre syndrome. Proc Natl Acad Sci U S A (1989) 1.88

Genetic heterogeneity and clinical variability in the Sanfilippo syndrome (types A, B, and C). Clin Genet (1981) 1.84

Human alpha-N-acetylglucosaminidase. 1. Purification and properties. Eur J Biochem (1977) 1.82

Mr 46,000 mannose 6-phosphate specific receptor: its role in targeting of lysosomal enzymes. EMBO J (1987) 1.81

Phosphorylation of microtubule-associated protein tau: identification of the site for Ca2(+)-calmodulin dependent kinase and relationship with tau phosphorylation in Alzheimer tangles. EMBO J (1990) 1.80

Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity. Exp Neurol (1997) 1.78

Deficiency of UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase in organs of I-cell patients. Biochem Biophys Res Commun (1982) 1.78

Phosphorylated oligosaccharides in lysosomal enzymes: identification of alpha-N-acetylglucosamine(1)phospho(6)mannose diester groups. Proc Natl Acad Sci U S A (1980) 1.73

Processing peptidase of Neurospora mitochondria. Two-step cleavage of imported ATPase subunit 9. Eur J Biochem (1984) 1.73

In vitro binding of plasma membrane-coated vesicle adaptors to the cytoplasmic domain of lysosomal acid phosphatase. J Biol Chem (1993) 1.72

The essential tyrosine of the internalization signal in lysosomal acid phosphatase is part of a beta turn. Cell (1991) 1.72

Juvenile and adult metachromatic leukodystrophy: partial restoration of arylsulfatase A (cerebroside sulfatase) activity by inhibitors of thiol proteinases. Proc Natl Acad Sci U S A (1983) 1.71

Diagnostic tests for bacterial infection from birth to 90 days--a systematic review. Arch Dis Child Fetal Neonatal Ed (1998) 1.70

Phylogenetic conservation of arylsulfatases. cDNA cloning and expression of human arylsulfatase B. J Biol Chem (1990) 1.69

Subcellular location of two enzymes involved in the synthesis of phosphorylated recognition markers in lysosomal enzymes. J Biol Chem (1981) 1.68

An alternative hypothesis of cellular transport of lysosomal enzymes in fibroblasts. Effect of inhibitors of lysosomal enzyme endocytosis on intra- and extra-cellular lysosomal enzyme activities. Biochem J (1978) 1.67

Isolation and characterization of phosphorylated oligosaccharides from alpha-N-acetylglucosaminidase that are recognized by cell-surface receptors. Eur J Biochem (1979) 1.67

Early embryonic death of mice deficient in gamma-adaptin. J Biol Chem (1999) 1.64

Protoplast transformation in coryneform bacteria and introduction of an alpha-amylase gene from Bacillus amyloliquefaciens into Brevibacterium lactofermentum. Appl Environ Microbiol (1986) 1.63

Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiency. Nat Genet (2001) 1.62

Congenital disorder of glycosylation-Ic: case report and genetic defect. Neuropediatrics (2000) 1.58

Human lysosomal acid phosphatase: cloning, expression and chromosomal assignment. EMBO J (1988) 1.57

Rapid, phenotypic HIV-1 drug sensitivity assay for protease and reverse transcriptase inhibitors. J Clin Virol (1999) 1.57

Purification and characterization of acetoin:2,6-dichlorophenolindophenol oxidoreductase, dihydrolipoamide dehydrogenase, and dihydrolipoamide acetyltransferase of the Pelobacter carbinolicus acetoin dehydrogenase enzyme system. J Bacteriol (1991) 1.57

The cytoplasmic tail of lysosomal acid phosphatase contains overlapping but distinct signals for basolateral sorting and rapid internalization in polarized MDCK cells. EMBO J (1993) 1.57

High residual arylsulfatase A (ARSA) activity in a patient with late-infantile metachromatic leukodystrophy. Am J Hum Genet (1993) 1.55

Is movement of mannose 6-phosphate-specific receptor triggered by binding of lysosomal enzymes? J Cell Biol (1987) 1.54

The race-specific elicitor, NIP1, from the barley pathogen, Rhynchosporium secalis, determines avirulence on host plants of the Rrs1 resistance genotype. EMBO J (1995) 1.54

Autofluorescence bronchoscopy with white light bronchoscopy compared with white light bronchoscopy alone for the detection of precancerous lesions: a European randomised controlled multicentre trial. Thorax (2005) 1.51

Strong constraints on the rare decays B(s)(0) → μ+ μ- and B0 → μ+ μ-. Phys Rev Lett (2012) 1.50

First observation of the decays B(0) → D(+)K(-)π(+)π(-) and B(-) → D(0)K(-)π(+)π(-). Phys Rev Lett (2012) 1.50

Carbohydrate-free carboxypeptidase Y is transferred into the lysosome-like yeast vacuole. Biochem Biophys Res Commun (1982) 1.49

1.3 A structure of arylsulfatase from Pseudomonas aeruginosa establishes the catalytic mechanism of sulfate ester cleavage in the sulfatase family. Structure (2001) 1.49

The proteasome participates in degradation of mutant alpha 1-antitrypsin Z in the endoplasmic reticulum of hepatoma-derived hepatocytes. J Biol Chem (2001) 1.49

Crystal structure of human arylsulfatase A: the aldehyde function and the metal ion at the active site suggest a novel mechanism for sulfate ester hydrolysis. Biochemistry (1998) 1.48

Manifestations and treatment of Schimke immuno-osseous dysplasia: 14 new cases and a review of the literature. Eur J Pediatr (2000) 1.48

Lysosomal enzyme precursors in human fibroblasts. Activation of cathepsin D precursor in vitro and activity of beta-hexosaminidase A precursor towards ganglioside GM2. Eur J Biochem (1982) 1.48

Internalization of blocking antibodies against mannose-6-phosphate specific receptors. EMBO J (1985) 1.48

Birthweight, early passive respiratory system mechanics, and ventilator requirements as predictors of outcome in premature infants with respiratory failure. Pediatr Pulmonol (1991) 1.48

The iron sulfur protein AtsB is required for posttranslational formation of formylglycine in the Klebsiella sulfatase. J Biol Chem (1999) 1.46

Identification of N-sulphated disaccharide units in heparin-like polysaccharides. Biochem J (1979) 1.44

Enhanced breakdown of arylsulfatase A in multiple sulfatase deficiency. Eur J Biochem (1982) 1.44

Determinants of parental authorization for involvement of newborn infants in clinical trials. Pediatrics (1997) 1.44

Synthesis and processing of arylsulfatase A in human skin fibroblasts. Hoppe Seylers Z Physiol Chem (1982) 1.44

Phenotype of arylsulfatase A-deficient mice: relationship to human metachromatic leukodystrophy. Proc Natl Acad Sci U S A (1996) 1.44

Evidence of carotid atherosclerosis in orthopantomograms and the risk for future cardiovascular events. Vasa (2010) 1.43

Determination of the X(3872) meson quantum numbers. Phys Rev Lett (2013) 1.42

Influence of site specifically altered Mip proteins on intracellular survival of Legionella pneumophila in eukaryotic cells. Infect Immun (1995) 1.42

Identification and molecular characterization of the gene coding for acetaldehyde dehydrogenase II (acoD) of Alcaligenes eutrophus. J Bacteriol (1992) 1.42

Fetal cleft lip repair in rabbits: histology and role of hyaluronic acid. J Oral Maxillofac Surg (1992) 1.41

Normal lysosomal morphology and function in LAMP-1-deficient mice. J Biol Chem (1999) 1.41

Prion protein binds copper within the physiological concentration range. J Biol Chem (2001) 1.40

Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation. J Neurochem (2002) 1.40

Sanfilippo A disease in the fetus. J Med Genet (1974) 1.40