Published in J Cell Sci on January 01, 1998
Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med (2001) 9.99
Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia. J Cell Biol (1999) 8.24
The cofilin pathway in breast cancer invasion and metastasis. Nat Rev Cancer (2007) 3.71
Spatial control of actin polymerization during neutrophil chemotaxis. Nat Cell Biol (1999) 3.45
The actin-based nanomachine at the leading edge of migrating cells. Biophys J (1999) 3.19
The regulation of cell motility and chemotaxis by phospholipid signaling. J Cell Sci (2008) 3.04
Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex. J Cell Biol (2000) 2.94
Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation. J Cell Biol (2009) 2.90
Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling. J Cell Biol (2010) 2.65
A Mena invasion isoform potentiates EGF-induced carcinoma cell invasion and metastasis. Dev Cell (2008) 2.65
Role of cofilin in epidermal growth factor-stimulated actin polymerization and lamellipod protrusion. J Cell Biol (2000) 2.56
Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation. J Cell Biol (2004) 2.55
The physiological significance of beta -actin mRNA localization in determining cell polarity and directional motility. Proc Natl Acad Sci U S A (2001) 2.40
Relationship between Arp2/3 complex and the barbed ends of actin filaments at the leading edge of carcinoma cells after epidermal growth factor stimulation. J Cell Biol (1999) 2.14
Phosphorylation of ADF/cofilin abolishes EGF-induced actin nucleation at the leading edge and subsequent lamellipod extension. J Cell Biol (2000) 2.10
Neurotrophin regulation of beta-actin mRNA and protein localization within growth cones. J Cell Biol (1999) 1.99
Cofilin promotes stimulus-induced lamellipodium formation by generating an abundant supply of actin monomers. J Cell Biol (2007) 1.93
N-WASP regulates the epithelial junctional actin cytoskeleton through a non-canonical post-nucleation pathway. Nat Cell Biol (2011) 1.92
Synergistic interaction between the Arp2/3 complex and cofilin drives stimulated lamellipod extension. J Cell Sci (2004) 1.89
Temporal and spatial distribution of activated Pak1 in fibroblasts. J Cell Biol (2000) 1.82
WASP family members and formin proteins coordinate regulation of cell protrusions in carcinoma cells. J Cell Biol (2008) 1.73
Direct dynamin-actin interactions regulate the actin cytoskeleton. EMBO J (2010) 1.67
The Nck-interacting kinase phosphorylates ERM proteins for formation of lamellipodium by growth factors. Proc Natl Acad Sci U S A (2006) 1.64
Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding. J Cell Biol (2008) 1.61
Interactions of elongation factor 1alpha with F-actin and beta-actin mRNA: implications for anchoring mRNA in cell protrusions. Mol Biol Cell (2002) 1.60
Biophysical integration of effects of epidermal growth factor and fibronectin on fibroblast migration. Biophys J (1999) 1.58
Capping protein terminates but does not initiate chemoattractant-induced actin assembly in Dictyostelium. J Cell Biol (1997) 1.57
Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia. J Cell Sci (2010) 1.53
Regulation of actin dynamics by annexin 2. EMBO J (2006) 1.45
Phosphatidylinositol 4,5-bisphosphate induces actin stress-fiber formation and inhibits membrane ruffling in CV1 cells. J Cell Biol (2001) 1.43
Arp2/3 complex-dependent actin networks constrain myosin II function in driving retrograde actin flow. J Cell Biol (2012) 1.42
Enhanced EGFP-chromophore-assisted laser inactivation using deficient cells rescued with functional EGFP-fusion proteins. Proc Natl Acad Sci U S A (2007) 1.35
The distinct roles of Ras and Rac in PI 3-kinase-dependent protrusion during EGF-stimulated cell migration. J Cell Sci (2007) 1.34
Epidermal growth factor receptor distribution during chemotactic responses. Mol Biol Cell (2000) 1.34
β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation. Mol Biol Cell (2013) 1.29
Molecular dissection of zyxin function reveals its involvement in cell motility. J Cell Biol (1999) 1.27
Protrusive growth from giant liposomes driven by actin polymerization. Proc Natl Acad Sci U S A (1999) 1.25
RhoA/ROCK-mediated switching between Cdc42- and Rac1-dependent protrusion in MTLn3 carcinoma cells. Exp Cell Res (2008) 1.22
Btk regulates B cell receptor-mediated antigen processing and presentation by controlling actin cytoskeleton dynamics in B cells. J Immunol (2009) 1.20
X-linked inhibitor of apoptosis protein (XIAP) mediates cancer cell motility via Rho GDP dissociation inhibitor (RhoGDI)-dependent regulation of the cytoskeleton. J Biol Chem (2011) 1.17
A Rac1/Cdc42 GTPase-specific small molecule inhibitor suppresses growth of primary human prostate cancer xenografts and prolongs survival in mice. PLoS One (2013) 1.17
β-Actin mRNA compartmentalization enhances focal adhesion stability and directs cell migration. Genes Dev (2012) 1.13
Protein tyrosine phosphatase phi regulates paxillin tyrosine phosphorylation and mediates colony-stimulating factor 1-induced morphological changes in macrophages. Mol Cell Biol (2001) 1.09
Actin dynamics: from nanoscale to microscale. Annu Rev Biophys (2010) 1.09
Activation of ADF/cofilin mediates attractive growth cone turning toward nerve growth factor and netrin-1. Dev Neurobiol (2010) 1.09
Cdc42 is required for EGF-stimulated protrusion and motility in MTLn3 carcinoma cells. J Cell Sci (2007) 1.07
Resveratrol and estradiol exert disparate effects on cell migration, cell surface actin structures, and focal adhesion assembly in MDA-MB-231 human breast cancer cells. Neoplasia (2005) 1.06
A balance of Bruton's tyrosine kinase and SHIP activation regulates B cell receptor cluster formation by controlling actin remodeling. J Immunol (2011) 1.06
Arp2/3 complex activity in filopodia of spreading cells. BMC Cell Biol (2008) 1.05
Villin enhances hepatocyte growth factor-induced actin cytoskeleton remodeling in epithelial cells. Mol Biol Cell (2003) 1.02
beta-Arrestins scaffold cofilin with chronophin to direct localized actin filament severing and membrane protrusions downstream of protease-activated receptor-2. J Biol Chem (2010) 1.01
Talin regulates moesin-NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis. J Cell Biol (2014) 1.01
Quantification of PtdIns(3,4,5)P(3) dynamics in EGF-stimulated carcinoma cells: a comparison of PH-domain-mediated methods with immunological methods. Biochem J (2008) 0.99
HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1. Proc Natl Acad Sci U S A (2010) 0.98
Activation of ezrin/radixin/moesin mediates attractive growth cone guidance through regulation of growth cone actin and adhesion receptors. J Neurosci (2012) 0.97
Visualization of actin polymerization in invasive structures of macrophages and carcinoma cells using photoconvertible β-actin-Dendra2 fusion proteins. PLoS One (2011) 0.96
Coronin 2A regulates a subset of focal-adhesion-turnover events through the cofilin pathway. J Cell Sci (2009) 0.96
Myo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesicles. Mol Biol Cell (2012) 0.96
Gelsolin mediates collagen phagocytosis through a rac-dependent step. Mol Biol Cell (2003) 0.95
Myo1c facilitates G-actin transport to the leading edge of migrating endothelial cells. J Cell Biol (2012) 0.93
Actin reorganization is required for the formation of polarized B cell receptor signalosomes in response to both soluble and membrane-associated antigens. J Immunol (2012) 0.92
Placental growth factor (PlGF) enhances breast cancer cell motility by mobilising ERK1/2 phosphorylation and cytoskeletal rearrangement. Br J Cancer (2010) 0.92
The role of actin turnover in retrograde actin network flow in neuronal growth cones. PLoS One (2012) 0.91
Arkadia regulates tumor metastasis by modulation of the TGF-β pathway. Cancer Res (2013) 0.91
Spatial regulation of RhoC activity defines protrusion formation in migrating cells. J Cell Sci (2013) 0.90
Vasodilator-stimulated phosphoprotein (VASP) induces actin assembly in dendritic spines to promote their development and potentiate synaptic strength. J Biol Chem (2010) 0.88
E3 ligase activity of XIAP RING domain is required for XIAP-mediated cancer cell migration, but not for its RhoGDI binding activity. PLoS One (2012) 0.87
Protein expression changes during human triple negative breast cancer cell line progression to lymph node metastasis in a xenografted model in nude mice. Cancer Biol Ther (2012) 0.86
Actin reorganization as the molecular basis for the regulation of apoptosis in gastrointestinal epithelial cells. Cell Death Differ (2012) 0.84
High molecular weight tropomyosins regulate osteoclast cytoskeletal morphology. Bone (2008) 0.83
Distributed actin turnover in the lamellipodium and FRAP kinetics. Biophys J (2013) 0.83
PTPRN2 and PLCβ1 promote metastatic breast cancer cell migration through PI(4,5)P2-dependent actin remodeling. EMBO J (2015) 0.82
The chemotactic defect in wiskott-Aldrich syndrome macrophages is due to the reduced persistence of directional protrusions. PLoS One (2012) 0.81
Use of green fluorescent protein-conjugated beta-actin as a novel molecular marker for in vitro tumor cell chemotaxis assay. Biotechnol Prog (2000) 0.80
Labeling F-actin barbed ends with rhodamine-actin in permeabilized neuronal growth cones. J Vis Exp (2011) 0.79
Profilin1 regulates invadopodium maturation in human breast cancer cells. Eur J Cell Biol (2014) 0.79
Control of cell migration through mRNA localization and local translation. Wiley Interdiscip Rev RNA (2014) 0.79
Specific Intensity Direct Current (DC) Electric Field Improves Neural Stem Cell Migration and Enhances Differentiation towards βIII-Tubulin+ Neurons. PLoS One (2015) 0.78
Differences in adhesion and protrusion properties correlate with differences in migration speed under EGF stimulation. BMC Biophys (2012) 0.78
Protein kinase C activation decreases peripheral actin network density and increases central nonmuscle myosin II contractility in neuronal growth cones. Mol Biol Cell (2013) 0.78
The Nck-interacting kinase NIK increases Arp2/3 complex activity by phosphorylating the Arp2 subunit. J Cell Biol (2015) 0.77
ARF6 promotes the formation of Rac1 and WAVE-dependent ventral F-actin rosettes in breast cancer cells in response to epidermal growth factor. PLoS One (2015) 0.77
A Phosphatidic Acid (PA) conveyor system of continuous intracellular transport from cell membrane to nucleus maintains EGF receptor homeostasis. Oncotarget (2016) 0.77
Analyzing actin dynamics during the activation of the B cell receptor in live B cells. Biochem Biophys Res Commun (2012) 0.77
Repulsive axon guidance cues ephrin-A2 and slit3 stop protrusion of the growth cone leading margin concurrently with inhibition of ADF/cofilin and ERM proteins. Cytoskeleton (Hoboken) (2012) 0.76
The alternatively-included 11a sequence modifies the effects of Mena on actin cytoskeletal organization and cell behavior. Sci Rep (2016) 0.76
Chronophin coordinates cell leading edge dynamics by controlling active cofilin levels. Proc Natl Acad Sci U S A (2015) 0.75
Actin polymerization overshoots induced by plus-end capping. Phys Biol (2010) 0.75
Integrated Analysis of Intracellular Dynamics of MenaINV Cancer Cells in a 3D Matrix. Biophys J (2017) 0.75
JG6, a novel marine-derived oligosaccharide, suppresses breast cancer metastasis via binding to cofilin. Oncotarget (2014) 0.75
Factors Associated with Nitric Oxide-mediated β2 Integrin Inhibition of Neutrophils. J Biol Chem (2015) 0.75
Temporal comparisons in bacterial chemotaxis. Proc Natl Acad Sci U S A (1986) 5.67
Impulse responses in bacterial chemotaxis. Cell (1982) 4.95
Adaptation kinetics in bacterial chemotaxis. J Bacteriol (1983) 4.31
Signal processing times in bacterial chemotaxis. Nature (1982) 3.81
The contractile basis of amoeboid movement. I. The chemical control of motility in isolated cytoplasm. J Cell Biol (1973) 3.49
Cytoplasmic structure and contractility in amoeboid cells. Int Rev Cytol (1979) 3.33
A critical step in metastasis: in vivo analysis of intravasation at the primary tumor. Cancer Res (2000) 3.03
The contractile basis of amoeboid movement. V. The control of gelation, solation, and contraction in extracts from Dictyostelium discoideum. J Cell Biol (1977) 2.94
Chemotactic signaling in filamentous cells of Escherichia coli. J Bacteriol (1985) 2.69
Role of cofilin in epidermal growth factor-stimulated actin polymerization and lamellipod protrusion. J Cell Biol (2000) 2.56
Role of coated vesicles, microfilaments, and calmodulin in receptor-mediated endocytosis by cultured B lymphoblastoid cells. J Cell Biol (1980) 2.39
Coordination of flagella on filamentous cells of Escherichia coli. J Bacteriol (1983) 2.28
Functional characterization of the Cdc42p binding domain of yeast Ste20p protein kinase. EMBO J (1997) 2.20
Relationship between Arp2/3 complex and the barbed ends of actin filaments at the leading edge of carcinoma cells after epidermal growth factor stimulation. J Cell Biol (1999) 2.14
Phosphorylation of ADF/cofilin abolishes EGF-induced actin nucleation at the leading edge and subsequent lamellipod extension. J Cell Biol (2000) 2.10
The product of the c-ets-1 proto-oncogene and the related Ets2 protein act as transcriptional activators of the long terminal repeat of human T cell leukemia virus HTLV-1. EMBO J (1990) 2.03
The collection of the motile population of cells from a living tumor. Cancer Res (2000) 1.95
Regulation of protrusion shape and adhesion to the substratum during chemotactic responses of mammalian carcinoma cells. Exp Cell Res (1998) 1.91
Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway. J Biol Chem (1999) 1.82
The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation. Endocr Rev (1999) 1.78
The F-actin side binding activity of the Arp2/3 complex is essential for actin nucleation and lamellipod extension. Curr Biol (2001) 1.62
Capping protein terminates but does not initiate chemoattractant-induced actin assembly in Dictyostelium. J Cell Biol (1997) 1.57
Actin filaments are severed by both native and recombinant dictyostelium cofilin but to different extents. Cell Motil Cytoskeleton (2000) 1.57
Cell motility of tumor cells visualized in living intact primary tumors using green fluorescent protein. Cancer Res (1998) 1.49
Does body mass index of infertile women have an impact on IVF procedure and outcome? J Assist Reprod Genet (2000) 1.48
Calmodulin localization during capping and receptor-mediated endocytosis. Nature (1981) 1.46
A Dictyostelium mutant deficient in severin, an F-actin fragmenting protein, shows normal motility and chemotaxis. J Cell Biol (1989) 1.40
Lamellipodia in invasion. Semin Cancer Biol (2001) 1.40
Chemoattractant-induced lamellipod extension. Microsc Res Tech (1998) 1.35
Epidermal growth factor receptor distribution during chemotactic responses. Mol Biol Cell (2000) 1.34
The identification of F actin of the pollen tube and protoplast of Amaryllis belladonna. Exp Cell Res (1974) 1.34
Characterization of quail Pax-6 (Pax-QNR) proteins expressed in the neuroretina. Mol Cell Biol (1993) 1.33
Specific requirement for the p85-p110alpha phosphatidylinositol 3-kinase during epidermal growth factor-stimulated actin nucleation in breast cancer cells. J Biol Chem (2000) 1.28
A Dictyostelium mutant lacking an F-actin cross-linking protein, the 120-kD gelation factor. J Cell Biol (1990) 1.24
The Dictyostelium MAP kinase ERK2 regulates multiple, independent developmental pathways. Genes Dev (1996) 1.22
Arg/Abl2 promotes invasion and attenuates proliferation of breast cancer in vivo. Oncogene (2012) 1.20
Rapid and transient expression of Ets2 in mature macrophages following stimulation with cMGF, LPS, and PKC activators. Genes Dev (1990) 1.19
Ligand-induced changes in the location of actin, myosin, 95K (alpha-actinin), and 120K protein in amebae of Dictyostelium discoideum. J Cell Biol (1985) 1.17
A monoclonal antibody (LYP18) directed against the blood platelet glycoprotein IIb/IIIa complex inhibits human melanoma growth in vivo. Blood (1989) 1.14
Selection of chemotaxis mutants of Dictyostelium discoideum. J Cell Biol (1987) 1.11
The c-erbA alpha-encoded thyroid hormone receptor is phosphorylated in its amino terminal domain by casein kinase II. Oncogene (1989) 1.10
Large human sperm vacuoles observed in motile spermatozoa under high magnification: nuclear thumbprints linked to failure of chromatin condensation. Hum Reprod (2011) 1.09
Protein tyrosine phosphatase phi regulates paxillin tyrosine phosphorylation and mediates colony-stimulating factor 1-induced morphological changes in macrophages. Mol Cell Biol (2001) 1.09
Sonic hedgehog regulates otic capsule chondrogenesis and inner ear development in the mouse embryo. Dev Biol (2002) 1.05
Receptor-mediated endocytosis: machinery and regulation of the clathrin-coated vesicle pathway. Int Rev Exp Pathol (1983) 1.04
Arp2/3 complex-mediated actin polymerisation occurs on specific pre-existing networks in cells and requires spatial restriction to sustain functional lamellipod extension. Cell Motil Cytoskeleton (2006) 1.03
Nuclear localization signals, DNA binding, and transactivation properties of quail Pax-6 (Pax-QNR) isoforms. Cell Growth Differ (1995) 1.03
Imaging of cancer invasion and metastasis using green fluorescent protein. Eur J Cancer (2000) 0.99
Phosphoinositide 3-kinase signaling is critical for ErbB3-driven breast cancer cell motility and metastasis. Oncogene (2011) 0.97
Irreversible inhibition of S-adenosylhomocysteine hydrolase by nucleoside analogs. Arch Biochem Biophys (1981) 0.97
A method for the morphological identification of contractile filaments in single cells. Exp Cell Res (1973) 0.97
Ecology of leishmaniasis in the south of France. 20. Dispersal of Phlebotomus ariasi Tonnoir, 1921 as a factor in the spread of visceral leishmaniasis in the Cévennes. Ann Parasitol Hum Comp (1984) 0.97
Identification of the aspartic proteinases from human erythrocyte membranes and gastric mucosa (slow-moving proteinase) as catalytically equivalent to cathepsin E. Biochem J (1988) 0.95
Reciprocal interactions between the actin lattice and cell membrane. Neurosci Res Program Bull (1981) 0.95
Receptor-mediated endocytosis by clathrin-coated vesicles: evidence for a dynamic pathway. Cold Spring Harb Symp Quant Biol (1982) 0.95
Involvement of poly (ADP-ribose)-polymerase in the Pax-6 gene regulation in neuroretina. Oncogene (1999) 0.94
Criteria for establishing a standardized method for determining alkaline phosphatase activity in human serum. Clin Chem (1977) 0.94
MAP kinase function in amoeboid chemotaxis. J Cell Sci (1998) 0.92
Human melanoma cell lines differ in their capacity to release ADP and aggregate platelets. Br J Haematol (1994) 0.92
Chemotaxis of metastatic tumor cells: clues to mechanisms from the Dictyostelium paradigm. Cancer Metastasis Rev (1992) 0.91
Suitability of control materials. General principles and methods of investigation. Clin Chem (1981) 0.91
Ets1, when fused to the GAL4 DNA binding domain, efficiently enhances galactose promotor dependent gene expression in yeast. Oncogene (1991) 0.91
Dual role of cAMP and involvement of both G-proteins and ras in regulation of ERK2 in Dictyostelium discoideum. EMBO J (1996) 0.91
Aginactin, an agonist-regulated F-actin capping activity is associated with an Hsc70 in Dictyostelium. J Biol Chem (1993) 0.91
[Ecology of leishmaniasis in the south of France. -- 12. Horizontal dispersion of Phlebotomus ariasi Tonnoir, 1921. Preliminary experiments (author's transl)]. Ann Parasitol Hum Comp (1980) 0.91
N-terminal domains of the class ia phosphoinositide 3-kinase regulatory subunit play a role in cytoskeletal but not mitogenic signaling. J Biol Chem (2001) 0.91
The mechanochemical basis of amoeboid movement. I. Ionic requirements for maintaining viscoelasticity and contractility of Amoeba cytoplasm. Exp Cell Res (1976) 0.90
Characterization of a new melanocyte-specific gene (QNR-71) expressed in v-myc-transformed quail neuroretina. EMBO J (1996) 0.90
[Ecology of leishmaniasis in south France. 17. Sampling of Phlebotomus by the method of adhesive traps. Comparison with the technic of capture on human bait]. Ann Parasitol Hum Comp (1982) 0.89
Preliminary field observations on the flight speed of a phlebotomine sandfly. Trans R Soc Trop Med Hyg (1986) 0.89
Expression of PNA-binding sites on specific glycoproteins by human melanoma cells is associated with a high metastatic potential. J Cell Biochem (1994) 0.89
Selection of normal spermatozoa with a vacuole-free head (x6300) improves selection of spermatozoa with intact DNA in patients with high sperm DNA fragmentation rates. Andrologia (2012) 0.89
Suppression of ruffling by the EGF receptor in chemotactic cells. Exp Cell Res (1998) 0.87
Chemotaxis assays for eukaryotic cells. Curr Protoc Cell Biol (2001) 0.87
The contractile basis of amoeboid movement III. Structure and dynamics of motile extracts and membrane fragments from Dictyostelium discoideum and Amoeba proteus. Prog Clin Biol Res (1977) 0.87
Metastases of human tumors in experimental animals. Anticancer Res (1988) 0.87
Two human melanoma cell-line variants with enhanced in vivo tumor growth and metastatic capacity do not express the beta 3 integrin subunit. Eur J Biochem (1994) 0.87
Tumor necrosis factor-alpha -308 polymorphism in infertile men with altered sperm production or motility. Hum Reprod (2008) 0.86
Oocyte aneuploidy mechanisms are different in two situations of increased chromosomal risk: older patients and patients with recurrent implantation failure after in vitro fertilization. Fertil Steril (2007) 0.86
A genome-wide DNA methylation study in azoospermia. Andrology (2013) 0.85
The isolation of microquantities of myosin from Amoeba proteus and Chaos carolinensis. Anal Biochem (1977) 0.85
Purification and characterization of aginactin, a newly identified agonist-regulated actin-capping protein from Dictyostelium amoebae. J Biol Chem (1991) 0.85
Isolation and behavioral analysis of mutants defective in cytoskeletal proteins. Cell Motil Cytoskeleton (1989) 0.85
Tumourigenic phenotypes of human melanoma cell lines in nude mice determined by an active antitumour mechanism. Br J Cancer (1985) 0.84