CRP interacts with promoter-bound sigma54 RNA polymerase and blocks transcriptional activation of the dctA promoter.

PubWeight™: 0.91‹?›

🔗 View Article (PMC 1170427)

Published in EMBO J on February 02, 1998

Authors

Y P Wang1, A Kolb, M Buck, J Wen, F O'Gara, H Buc

Author Affiliations

1: Unité de Physicochimie des Macromolécules Biologiques (URA1149 du CNRS), Institut Pasteur, 75724 Paris cedex 15, France.

Articles cited by this

Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol (1980) 287.68

Crystal structure of a CAP-DNA complex: the DNA is bent by 90 degrees. Science (1991) 11.45

Control site location and transcriptional regulation in Escherichia coli. Microbiol Rev (1991) 8.11

Transcriptional regulation by cAMP and its receptor protein. Annu Rev Biochem (1993) 6.49

Transcription of glnA in E. coli is stimulated by activator bound to sites far from the promoter. Cell (1986) 5.81

Cyclic AMP in prokaryotes. Microbiol Rev (1992) 5.44

Function of a bacterial activator protein that binds to transcriptional enhancers. Science (1989) 5.27

The sigma 54 bacterial enhancer-binding protein family: mechanism of action and phylogenetic relationship of their functional domains. J Bacteriol (1993) 4.34

In a class of its own--the RNA polymerase sigma factor sigma 54 (sigma N). Mol Microbiol (1993) 4.00

Selection of DNA binding sites by regulatory proteins. II. The binding specificity of cyclic AMP receptor protein to recognition sites. J Mol Biol (1988) 3.99

Promoters responsive to DNA bending: a common theme in prokaryotic gene expression. Microbiol Rev (1994) 3.81

The phosphorylated form of the enhancer-binding protein NTRC has an ATPase activity that is essential for activation of transcription. Cell (1991) 3.70

Synthetic curved DNA sequences can act as transcriptional activators in Escherichia coli. EMBO J (1989) 3.69

Stringent spacing requirements for transcription activation by CRP. Cell (1990) 3.52

DNA-looping and enhancer activity: association between DNA-bound NtrC activator and RNA polymerase at the bacterial glnA promoter. Proc Natl Acad Sci U S A (1990) 3.48

In vivo studies on the interaction of RNA polymerase-sigma 54 with the Klebsiella pneumoniae and Rhizobium meliloti nifH promoters. The role of NifA in the formation of an open promoter complex. J Mol Biol (1989) 3.43

Mutations that alter the ability of the Escherichia coli cyclic AMP receptor protein to activate transcription. Nucleic Acids Res (1990) 3.08

Probing the Escherichia coli glnALG upstream activation mechanism in vivo. Proc Natl Acad Sci U S A (1988) 3.01

Transcription activation at class II CAP-dependent promoters: two interactions between CAP and RNA polymerase. Cell (1996) 2.88

Unusual oligomerization required for activity of NtrC, a bacterial enhancer-binding protein. Science (1997) 2.81

Coordinate regulation of adenylate cyclase and carbohydrate permeases by the phosphoenolpyruvate:sugar phosphotransferase system in Salmonella typhimurium. J Biol Chem (1975) 2.64

CAP and RNA polymerase interactions with the lac promoter: binding stoichiometry and long range effects. Nucleic Acids Res (1983) 2.60

Prokaryotic transcriptional enhancers and enhancer-binding proteins. Trends Biochem Sci (1991) 2.56

Helical phase dependent action of CRP: effect of the distance between the CRP site and the -35 region on promoter activity. Nucleic Acids Res (1990) 2.40

Role of the RNA polymerase alpha subunit in transcription activation. Mol Microbiol (1992) 2.37

On the different binding affinities of CRP at the lac, gal and malT promoter regions. Nucleic Acids Res (1983) 2.34

Prokaryotic enhancer-binding proteins reflect eukaryote-like modularity: the puzzle of nitrogen regulatory protein C. J Bacteriol (1993) 2.32

Specific binding of the transcription factor sigma-54 to promoter DNA. Nature (1992) 2.25

Transcription activation at class II CAP-dependent promoters. Mol Microbiol (1997) 2.22

Escherichia coli catabolite gene activator protein mutants defective in positive control of lac operon transcription. J Bacteriol (1991) 2.18

Novel proteins of the phosphotransferase system encoded within the rpoN operon of Escherichia coli. Enzyme IIANtr affects growth on organic nitrogen and the conditional lethality of an erats mutant. J Biol Chem (1995) 2.17

Identification of the activating region of catabolite gene activator protein (CAP): isolation and characterization of mutants of CAP specifically defective in transcription activation. Proc Natl Acad Sci U S A (1993) 2.08

Transcriptional activation of the Klebsiella pneumoniae nitrogenase promoter may involve DNA loop formation. Mol Microbiol (1987) 2.04

The central domain of Rhizobium meliloti NifA is sufficient to activate transcription from the R. meliloti nifH promoter. J Bacteriol (1989) 2.02

Identification, nucleotide sequence, and characterization of PspF, the transcriptional activator of the Escherichia coli stress-induced psp operon. J Bacteriol (1996) 1.98

Selectivity of the Escherichia coli RNA polymerase E sigma 38 for overlapping promoters and ability to support CRP activation. Nucleic Acids Res (1995) 1.98

Azotobacter vinelandii NIFL is a flavoprotein that modulates transcriptional activation of nitrogen-fixation genes via a redox-sensitive switch. Proc Natl Acad Sci U S A (1996) 1.89

Location, structure, and function of the target of a transcriptional activator protein. Genes Dev (1994) 1.88

Transcription factor recognition surface on the RNA polymerase alpha subunit is involved in contact with the DNA enhancer element. EMBO J (1996) 1.79

The Escherichia coli RNA polymerase alpha subunit: structure and function. Curr Opin Genet Dev (1995) 1.77

The central domain of Rhizobium leguminosarum DctD functions independently to activate transcription. J Bacteriol (1992) 1.60

Homologous interactions of lambda repressor and lambda Cro with the lambda operator. Cell (1986) 1.58

Protein crosslinking studies suggest that Rhizobium meliloti C4-dicarboxylic acid transport protein D, a sigma 54-dependent transcriptional activator, interacts with sigma 54 and the beta subunit of RNA polymerase. Proc Natl Acad Sci U S A (1995) 1.50

The isolated catalytic domain of NIFA, a bacterial enhancer-binding protein, activates transcription in vitro: activation is inhibited by NIFL. Proc Natl Acad Sci U S A (1994) 1.49

Mutations that create new promoters suppress the sigma 54 dependence of glnA transcription in Escherichia coli. J Bacteriol (1987) 1.44

Promoter determinants for Escherichia coli RNA polymerase holoenzyme containing sigma 38 (the rpoS gene product). Nucleic Acids Res (1995) 1.42

Transcriptional activation of the Klebsiella pneumoniae nifLA promoter by NTRC is face-of-the-helix dependent and the activator stabilizes the interaction of sigma 54-RNA polymerase with the promoter. EMBO J (1989) 1.40

Transcription of the Escherichia coli rrnB P1 promoter by the heat shock RNA polymerase (E sigma 32) in vitro. J Bacteriol (1993) 1.38

A proposed link between nitrogen and carbon metabolism involving protein phosphorylation in bacteria. Protein Sci (1992) 1.36

Mutant forms of the enhancer-binding protein NtrC can activate transcription from solution. J Mol Biol (1997) 1.33

Dual-function regulators: the cAMP receptor protein and the CytR regulator can act either to repress or to activate transcription depending on the context. Proc Natl Acad Sci U S A (1996) 1.31

Core RNA polymerase and promoter DNA interactions of purified domains of sigma N: bipartite functions. J Mol Biol (1995) 1.29

Mutations in the glnG gene of Escherichia coli that result in increased activity of nitrogen regulator I. J Bacteriol (1989) 1.23

Co-regulation by bent DNA. Functional substitutions of the integration host factor site at sigma 54-dependent promoter Pu of the upper-TOL operon by intrinsically curved sequences. J Biol Chem (1994) 1.22

A flexible partnership: the CytR anti-activator and the cAMP-CRP activator protein, comrades in transcription control. Mol Microbiol (1996) 1.21

Growth phase-dependent transcription of the sigma(54)-dependent Po promoter controlling the Pseudomonas-derived (methyl)phenol dmp operon of pVI150. J Bacteriol (1996) 1.15

CRP induces the repositioning of MalT at the Escherichia coli malKp promoter primarily through DNA bending. EMBO J (1994) 1.13

Role of the promoter in activation of transcription by nitrogen regulator I phosphate in Escherichia coli. J Bacteriol (1990) 1.12

CAP interacts with RNA polymerase in solution in the absence of promoter DNA. Nature (1993) 1.10

Design of cAMP-CRP-activated promoters in Escherichia coli. Mol Microbiol (1991) 1.02

Rhizobium meliloti and Rhizobium leguminosarum dctD gene products bind to tandem sites in an activation sequence located upstream of sigma 54-dependent dctA promoters. J Bacteriol (1990) 1.01

Substitutions at a single amino acid residue in the nitrogen-regulated activator protein NTRC differentially influence its activity in response to phosphorylation. Mol Microbiol (1991) 0.99

Tandem DctD-binding sites of the Rhizobium meliloti dctA upstream activating sequence are essential for optimal function despite a 50- to 100-fold difference in affinity for DctD. Mol Microbiol (1992) 0.97

Cooperative binding of DctD to the dctA upstream activation sequence of Rhizobium meliloti is enhanced in a constitutively active truncated mutant. J Biol Chem (1996) 0.95

A factor with Sp1 DNA-binding specificity stimulates Xenopus U6 snRNA in vivo transcription by RNA polymerase III. J Mol Biol (1992) 0.90

sigma54-dependent transcription of the Pseudomonas putida xylS operon is influenced by the IIANtr protein of the phosphotransferase system in Escherichia coli. Res Microbiol (1996) 0.84

The Escherichia coli cAMP receptor protein (CRP) represses the Rhizobium meliloti dctA promoter in a cAMP-dependent fashion. Mol Microbiol (1993) 0.80

Coordination of carbon and nitrogen metabolism. Res Microbiol (1997) 0.77

NtrBC-dependent expression from the Rhizobium meliloti dctA promoter in Escherichia coli. FEMS Microbiol Lett (1995) 0.76

Articles by these authors

Cyclic AMP receptor protein: role in transcription activation. Science (1984) 8.37

Transcriptional regulation by cAMP and its receptor protein. Annu Rev Biochem (1993) 6.49

Single nocturnal dose of an H2 receptor antagonist for the treatment of duodenal ulcer. Gut (1983) 4.47

HIV-1 reverse transcription. A termination step at the center of the genome. J Mol Biol (1994) 4.15

Regulation of nitrogen fixation by Rhizobia. Export of fixed N2 as NH+4. Biochim Biophys Acta (1976) 3.83

Synthetic curved DNA sequences can act as transcriptional activators in Escherichia coli. EMBO J (1989) 3.69

Is routine indwelling catheterisation of the bladder for caesarean section necessary? A systematic review. BJOG (2010) 3.54

Stringent spacing requirements for transcription activation by CRP. Cell (1990) 3.52

The leader mRNA of the histidine attenuator region resembles tRNAHis: possible general regulatory implications. Proc Natl Acad Sci U S A (1983) 3.43

In vivo studies on the interaction of RNA polymerase-sigma 54 with the Klebsiella pneumoniae and Rhizobium meliloti nifH promoters. The role of NifA in the formation of an open promoter complex. J Mol Biol (1989) 3.43

Traits of fluorescent Pseudomonas spp. involved in suppression of plant root pathogens. Microbiol Rev (1992) 3.41

Histone-like protein H1 (H-NS), DNA supercoiling, and gene expression in bacteria. Cell (1990) 3.39

Mutations that alter the ability of the Escherichia coli cyclic AMP receptor protein to activate transcription. Nucleic Acids Res (1990) 3.08

Multiple control of flagellum biosynthesis in Escherichia coli: role of H-NS protein and the cyclic AMP-catabolite activator protein complex in transcription of the flhDC master operon. J Bacteriol (1999) 2.80

Exploitation of gene(s) involved in 2,4-diacetylphloroglucinol biosynthesis to confer a new biocontrol capability to a Pseudomonas strain. Appl Environ Microbiol (1992) 2.78

Mechanism of CRP-cAMP activation of lac operon transcription initiation activation of the P1 promoter. J Mol Biol (1984) 2.74

Small, stable shuttle vectors based on the minimal pVS1 replicon for use in gram-negative, plant-associated bacteria. Mol Plant Microbe Interact (2000) 2.71

Kinetics of open complex formation between Escherichia coli RNA polymerase and the lac UV5 promoter. Evidence for a sequential mechanism involving three steps. Biochemistry (1985) 2.71

Kinetics of the allosteric interactions of phosphofructokinase from Escherichia coli. J Mol Biol (1968) 2.69

The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex. Proc Natl Acad Sci U S A (2001) 2.65

Reverse transcriptases and genomic variability: the accuracy of DNA replication is enzyme specific and sequence dependent. EMBO J (1990) 2.64

Polyamorphism in a metallic glass. Nat Mater (2007) 2.63

H1a, an E. coli DNA-binding protein which accumulates in stationary phase, strongly compacts DNA in vitro. Nucleic Acids Res (1984) 2.55

The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter. Hum Mol Genet (1999) 2.52

Mapping of single-stranded regions in duplex DNA at the sequence level: single-strand-specific cytosine methylation in RNA polymerase-promoter complexes. Proc Natl Acad Sci U S A (1983) 2.41

Escherichia coli protein analogs StpA and H-NS: regulatory loops, similar and disparate effects on nucleic acid dynamics. EMBO J (1996) 2.36

Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling. Gut (2008) 2.36

On the different binding affinities of CRP at the lac, gal and malT promoter regions. Nucleic Acids Res (1983) 2.34

Isomerization of a binary sigma-promoter DNA complex by transcription activators. Nat Struct Biol (2000) 2.32

Complete analysis of tRNA-modified nucleosides by high-performance liquid chromatography: the 29 modified nucleosides of Salmonella typhimurium and Escherichia coli tRNA. Anal Biochem (1983) 2.29

On the action of the cyclic AMP-cyclic AMP receptor protein complex at the Escherichia coli lactose and galactose promoter regions. EMBO J (1984) 2.29

Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression. J Clin Invest (1995) 2.26

Cisplatin and gemcitabine treatment for malignant mesothelioma: a phase II study. J Clin Oncol (1999) 2.25

NifA-dependent in vivo protection demonstrates that the upstream activator sequence of nif promoters is a protein binding site. Proc Natl Acad Sci U S A (1988) 2.10

Deletion mutagenesis of the Escherichia coli galactose operon promoter region. J Mol Biol (1983) 2.09

Lysis-centrifugation blood cultures in the detection of tissue-proven invasive candidiasis. Disseminated versus single-organ infection. Diagn Microbiol Infect Dis (1994) 2.04

A modified nucleotide in tRNA as a possible regulator of aerobiosis: synthesis of cis-2-methyl-thioribosylzeatin in the tRNA of Salmonella. Cell (1984) 1.90

The DNA-binding domain of the transcriptional activator protein NifA resides in its carboxy terminus, recognises the upstream activator sequences of nif promoters and can be separated from the positive control function of NifA. Nucleic Acids Res (1988) 1.89

E. coli RNA polymerase, deleted in the C-terminal part of its alpha-subunit, interacts differently with the cAMP-CRP complex at the lacP1 and at the galP1 promoter. Nucleic Acids Res (1993) 1.88

A refined solution structure of hen lysozyme determined using residual dipolar coupling data. Protein Sci (2001) 1.88

Topological unwinding of strong and weak promoters by RNA polymerase. A comparison between the lac wild-type and the UV5 sites of Escherichia coli. J Mol Biol (1987) 1.85

Binding of transcriptional activators to sigma 54 in the presence of the transition state analog ADP-aluminum fluoride: insights into activator mechanochemical action. Genes Dev (2001) 1.84

A mutant Arabidopsis heterotrimeric G-protein beta subunit affects leaf, flower, and fruit development. Plant Cell (2001) 1.82

cDNA-derived amino acid sequence of the 86-kDa subunit of the Ku antigen. J Biol Chem (1989) 1.81

Hydrogen exchange in native and denatured states of hen egg-white lysozyme. Proteins (1992) 1.79

DNA sequence elements located immediately upstream of the -10 hexamer in Escherichia coli promoters: a systematic study. Nucleic Acids Res (2000) 1.79

Mechanisms of retroviral recombination. Annu Rev Genet (2001) 1.75

Role of glutamic acid-181 in DNA-sequence recognition by the catabolite gene activator protein (CAP) of Escherichia coli: altered DNA-sequence-recognition properties of [Val181]CAP and [Leu181]CAP. Proc Natl Acad Sci U S A (1987) 1.75

Structural and dynamical properties of a denatured protein. Heteronuclear 3D NMR experiments and theoretical simulations of lysozyme in 8 M urea. Biochemistry (1997) 1.75

Site-directed mutagenesis of the Klebsiella pneumoniae nifL and nifH promoters and in vivo analysis of promoter activity. Nucleic Acids Res (1985) 1.73

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas. J Virol (1995) 1.72

A new target for CRP action at the malT promoter. EMBO J (1987) 1.71

Changes in the DNA structure of the lac UV5 promoter during formation of an open complex with Escherichia coli RNA polymerase. Biochemistry (1985) 1.69

Is DNA unwound by the cyclic AMP receptor protein? Nucleic Acids Res (1982) 1.69

Probing the structure, function, and interactions of the Escherichia coli H-NS and StpA proteins by using dominant negative derivatives. J Bacteriol (1996) 1.67

Fingerprinting bacterial chromosomal DNA with restriction endonuclease EcoRI: comparison of Rhizobium spp. and identification of mutants. Can J Microbiol (1979) 1.67

Choreoathetosis and diabetes. Diabetes Care (1997) 1.66

Modulated expression of promoters containing upstream curved DNA sequences by the Escherichia coli nucleoid protein H-NS. Mol Microbiol (1994) 1.66

Comparison of the binding sites for the Escherichia coli cAMP receptor protein at the lactose and galactose promoters. EMBO J (1983) 1.65

Human endogenous retroviral element K10 (HERV-K10) encodes a full-length gag homologous 73-kDa protein and a functional protease. AIDS Res Hum Retroviruses (1993) 1.63

The biocontrol strain Pseudomonas fluorescens F113 produces the Rhizobium small bacteriocin, N-(3-hydroxy-7-cis-tetradecenoyl)homoserine lactone, via HdtS, a putative novel N-acylhomoserine lactone synthase. Microbiology (2000) 1.63

Induction of hTERT expression and telomerase activity by estrogens in human ovary epithelium cells. Mol Cell Biol (2000) 1.60

Action of CAP on the malT promoter in vitro. J Bacteriol (1983) 1.59

Mechanochemical ATPases and transcriptional activation. Mol Microbiol (2002) 1.58

Transcription activation by the Escherichia coli cyclic AMP receptor protein. Receptors bound in tandem at promoters can interact synergistically. J Mol Biol (1994) 1.56

Delivery system for creation of one-step in vivo lac gene fusions in Pseudomonas spp. involved in biological control. Appl Environ Microbiol (1988) 1.54

Construction of a rhizosphere pseudomonad with potential to degrade polychlorinated biphenyls and detection of bph gene expression in the rhizosphere. Appl Environ Microbiol (1995) 1.54

Dimerization of the extracellular domain of the erythropoietin (EPO) receptor by EPO: one high-affinity and one low-affinity interaction. Biochemistry (1996) 1.52

A molecular mechanism for the repression of transcription by the H-NS protein. Mol Microbiol (2001) 1.51

Deletion analysis of the Klebsiella pneumoniae nitrogenase promoter: importance of spacing between conserved sequences around positions -12 and -24 for activation by the nifA and ntrC (glnG) products. J Bacteriol (1986) 1.51

Activation of the Pseudomonas TOL plasmid upper pathway operon. Identification of binding sites for the positive regulator XylR and for integration host factor protein. J Biol Chem (1991) 1.49

The biology of enhancer-dependent transcriptional regulation in bacteria: insights from genome sequences. FEMS Microbiol Lett (2000) 1.49

Effect of no treatment, cimetidine 1 g/day, cimetidine 2 g/day and cimetidine combined with atropine on nocturnal gastric secretion in cimetidine non-responders. Gut (1984) 1.47

Elastoderma. J Am Acad Dermatol (1995) 1.47

Pseudomonas for biocontrol of phytopathogens: from functional genomics to commercial exploitation. Curr Opin Biotechnol (2001) 1.46

A regulatory RNA (PrrB RNA) modulates expression of secondary metabolite genes in Pseudomonas fluorescens F113. J Bacteriol (2000) 1.45

The behavior of bacteria designed for biodegradation. Biotechnology (N Y) (1994) 1.44

Overlapping promoters and their control in Escherichia coli: the gal case. Proc Natl Acad Sci U S A (1986) 1.43

Increasing prevalence of gestational diabetes mellitus in Chinese women from 1999 to 2008. Diabet Med (2011) 1.43

Rickettsia conorii infection of C3H/HeN mice. A model of endothelial-target rickettsiosis. Lab Invest (1994) 1.41

Protein-DNA cross-linking at the lac promoter. Nucleic Acids Res (1991) 1.41

Single and double loop formation when deoR repressor binds to its natural operator sites. Cell (1989) 1.41

Alterations in the binding site of the cyclic AMP receptor protein at the Escherichia coli galactose operon regulatory region. Biochem J (1988) 1.40

Two fructose 6-phosphate kinase activities in Escherichia coli. J Biol Chem (1973) 1.40

Regulation of nitrogen fixation in Rhizobium spp. Isolation of mutants of Rhizobium trifolii which induce nitrogenase activity. Biochim Biophys Acta (1977) 1.38

Iron mediated methylthiolation of tRNA as a regulator of operon expression in Escherichia coli. Nucleic Acids Res (1982) 1.38

DNA distortion and nucleation of local DNA unwinding within sigma-54 (sigma N) holoenzyme closed promoter complexes. J Biol Chem (1994) 1.37

Point mutations change the thermal denaturation profile of a short DNA fragment containing the lactose control elements. Comparison between experiment and theory. EMBO J (1982) 1.37

Upstream curved sequences influence the initiation of transcription at the Escherichia coli galactose operon. J Mol Biol (1992) 1.36