Published in Nat Biotechnol on May 01, 1996
Biodegradation of aromatic compounds by Escherichia coli. Microbiol Mol Biol Rev (2001) 2.50
A small decrease of plastid transketolase activity in antisense tobacco transformants has dramatic effects on photosynthesis and phenylpropanoid metabolism. Plant Cell (2001) 1.79
The ascorbate transporter of Escherichia coli. J Bacteriol (2003) 1.36
Improvement of Escherichia coli production strains by modification of the phosphoenolpyruvate:sugar phosphotransferase system. Microb Cell Fact (2005) 1.35
Hyperproduction of tryptophan by Corynebacterium glutamicum with the modified pentose phosphate pathway. Appl Environ Microbiol (1999) 1.18
Crystal structures of Escherichia coli ATP-dependent glucokinase and its complex with glucose. J Bacteriol (2004) 1.09
Melanin-based high-throughput screen for L-tyrosine production in Escherichia coli. Appl Environ Microbiol (2007) 1.07
Metabolic engineering for the production of shikimic acid in an evolved Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system. Microb Cell Fact (2010) 1.05
Engineering Escherichia coli to overproduce aromatic amino acids and derived compounds. Microb Cell Fact (2014) 1.02
Characterization of growth and acid formation in a Bacillus subtilis pyruvate kinase mutant. Appl Environ Microbiol (2000) 1.02
Activating phosphoenolpyruvate carboxylase and phosphoenolpyruvate carboxykinase in combination for improvement of succinate production. Appl Environ Microbiol (2013) 1.01
Metabolic transcription analysis of engineered Escherichia coli strains that overproduce L-phenylalanine. Microb Cell Fact (2007) 1.01
Consequences of phosphoenolpyruvate:sugar phosphotranferase system and pyruvate kinase isozymes inactivation in central carbon metabolism flux distribution in Escherichia coli. Microb Cell Fact (2012) 1.01
Metabolic engineering for improving anthranilate synthesis from glucose in Escherichia coli. Microb Cell Fact (2009) 1.00
Metabolic engineering of Escherichia coli for L-tyrosine production by expression of genes coding for the chorismate mutase domain of the native chorismate mutase-prephenate dehydratase and a cyclohexadienyl dehydrogenase from Zymomonas mobilis. Appl Environ Microbiol (2008) 1.00
Genome engineering for improved recombinant protein expression in Escherichia coli. Microb Cell Fact (2014) 0.99
A genome-scale metabolic flux model of Escherichia coli K-12 derived from the EcoCyc database. BMC Syst Biol (2014) 0.99
Simultaneous utilization of glucose, xylose and arabinose in the presence of acetate by a consortium of Escherichia coli strains. Microb Cell Fact (2012) 0.96
Coutilization of glucose and glycerol enhances the production of aromatic compounds in an Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system. Microb Cell Fact (2008) 0.96
Glucose transport in Escherichia coli mutant strains with defects in sugar transport systems. J Bacteriol (2012) 0.96
Metabolic engineering of Escherichia coli for improving L-3,4-dihydroxyphenylalanine (L-DOPA) synthesis from glucose. J Ind Microbiol Biotechnol (2011) 0.95
An evolved xylose transporter from Zymomonas mobilis enhances sugar transport in Escherichia coli. Microb Cell Fact (2009) 0.92
Genetic changes during a laboratory adaptive evolution process that allowed fast growth in glucose to an Escherichia coli strain lacking the major glucose transport system. BMC Genomics (2012) 0.92
Constitutive expression of selected genes from the pentose phosphate and aromatic pathways increases the shikimic acid yield in high-glucose batch cultures of an Escherichia coli strain lacking PTS and pykF. Microb Cell Fact (2013) 0.92
Phosphotransferase system-independent glucose utilization in corynebacterium glutamicum by inositol permeases and glucokinases. Appl Environ Microbiol (2011) 0.91
One-step of tryptophan attenuator inactivation and promoter swapping to improve the production of L-tryptophan in Escherichia coli. Microb Cell Fact (2012) 0.91
Metabolic engineering of Escherichia coli for the production of riboflavin. Microb Cell Fact (2014) 0.89
Comparison of individual component deletions in a glucose-specific phosphotransferase system revealed their different applications. Sci Rep (2015) 0.86
Prolonged maltose-limited cultivation of Saccharomyces cerevisiae selects for cells with improved maltose affinity and hypersensitivity. Appl Environ Microbiol (2004) 0.84
Combining genotype improvement and statistical media optimization for isoprenoid production in E. coli. PLoS One (2013) 0.84
Ensemble modeling for aromatic production in Escherichia coli. PLoS One (2009) 0.84
Metabolic engineering of Escherichia coli to optimize melanin synthesis from glucose. Microb Cell Fact (2013) 0.83
Transcription analysis of central metabolism genes in Escherichia coli. Possible roles of sigma38 in their expression, as a response to carbon limitation. PLoS One (2009) 0.82
Production of cinnamic and p-hydroxycinnamic acid from sugar mixtures with engineered Escherichia coli. Microb Cell Fact (2015) 0.81
Shikimic acid: review of its analytical, isolation, and purification techniques from plant and microbial sources. J Chem Biol (2011) 0.80
Reduction of cell lysate viscosity during processing of poly(3-hydroxyalkanoates) by chromosomal integration of the staphylococcal nuclease gene in Pseudomonas putida. Appl Environ Microbiol (1999) 0.79
Carbon catabolite repression in Thermoanaerobacterium saccharolyticum. Biotechnol Biofuels (2012) 0.79
Catechol biosynthesis from glucose in Escherichia coli anthranilate-overproducer strains by heterologous expression of anthranilate 1,2-dioxygenase from Pseudomonas aeruginosa PAO1. Microb Cell Fact (2014) 0.79
Elucidation of the co-metabolism of glycerol and glucose in Escherichia coli by genetic engineering, transcription profiling, and (13)C metabolic flux analysis. Biotechnol Biofuels (2016) 0.79
Physiological and transcriptional characterization of Escherichia coli strains lacking interconversion of phosphoenolpyruvate and pyruvate when glucose and acetate are coutilized. Biotechnol Bioeng (2014) 0.78
PHB biosynthesis in catabolite repression mutant of Burkholderia sacchari. Curr Microbiol (2011) 0.76
Shikimic Acid Production in Escherichia coli: From Classical Metabolic Engineering Strategies to Omics Applied to Improve Its Production. Front Bioeng Biotechnol (2015) 0.75
Metabolic Characteristics of a Glucose-Utilizing Shewanella oneidensis Strain Grown under Electrode-Respiring Conditions. PLoS One (2015) 0.75
Production of Cinnamic and p-Hydroxycinnamic Acids in Engineered Microbes. Front Bioeng Biotechnol (2015) 0.75
A new target for gene therapeutics: telomerase. Nat Biotechnol (1996) 0.75
Enzyme I facilitates reverse flux from pyruvate to phosphoenolpyruvate in Escherichia coli. Nat Commun (2017) 0.75
L-Tryptophan Production in Escherichia coli Improved by Weakening the Pta-AckA Pathway. PLoS One (2016) 0.75
Metabolic Engineering of a Novel Muconic Acid Biosynthesis Pathway via 4-Hydroxybenzoic Acid in Escherichia coli. Appl Environ Microbiol (2015) 0.75
Rational engineering of multiple module pathways for the production of L-phenylalanine in Corynebacterium glutamicum. J Ind Microbiol Biotechnol (2015) 0.75
Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. Gene (1977) 114.87
Construction and characterization of new cloning vehicles. I. Ampicillin-resistant derivatives of the plasmid pMB9. Gene (1977) 12.93
Construction and characterization of new cloning vehicles. IV. Deletion derivatives of pBR322 and pBR325. Gene (1980) 12.14
Plasmids of Escherichia coli as cloning vectors. Methods Enzymol (1979) 11.41
Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostatin. Science (1977) 9.28
A general method for the purification of restriction enzymes. Nucleic Acids Res (1978) 7.92
Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity. Cell (2000) 6.92
Plasmid vector pBR322 and its special-purpose derivatives--a review. Gene (1986) 6.52
Saturated molecular map of the rice genome based on an interspecific backcross population. Genetics (1994) 6.22
Expression in Escherichia coli of chemically synthesized genes for human insulin. Proc Natl Acad Sci U S A (1979) 4.72
Construction and characterization of new cloning vehicles. VI. Plasmid pBR329, a new derivative of pBR328 lacking the 482-base-pair inverted duplication. Gene (1982) 4.36
Redesign of the coenzyme specificity of a dehydrogenase by protein engineering. Nature (1990) 4.16
The eye-specification proteins So and Eya form a complex and regulate multiple steps in Drosophila eye development. Cell (1997) 3.61
Y-Chromosome evidence for a northward migration of modern humans into Eastern Asia during the last Ice Age. Am J Hum Genet (1999) 3.60
Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response. Science (1999) 3.47
Gastric insufflation with the ProSeal laryngeal mask. Anesth Analg (2001) 3.26
Spin Seebeck insulator. Nat Mater (2010) 3.01
Alginate synthesis by Pseudomonas aeruginosa: a key pathogenic factor in chronic pulmonary infections of cystic fibrosis patients. Clin Microbiol Rev (1991) 2.87
The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment. Proc Natl Acad Sci U S A (1998) 2.85
Chromosomal regions associated with segregation distortion of molecular markers in F2, backcross, doubled haploid, and recombinant inbred populations in rice (Oryza sativa L.). Mol Gen Genet (1997) 2.70
The laryngeal mask airway for obstetric anaesthesia and neonatal resuscitation. Int J Obstet Anesth (1994) 2.66
Origin of replication of pBR345 plasmid DNA. Proc Natl Acad Sci U S A (1977) 2.40
Haplotypic divergence coupled with lack of diversity at the Arabidopsis thaliana alcohol dehydrogenase locus: roles for both balancing and directional selection? Genetics (1994) 2.38
A randomized controlled trial comparing the cuffed oropharyngeal airway and the laryngeal mask airway in spontaneously breathing anesthetized adults. Anesthesiology (1998) 2.33
Characterizing wild-type and mutant promoters of the tetracycline resistance gene in pBR313. Nucleic Acids Res (1979) 2.23
Characterization and regulation of the Pseudomonas aeruginosa algC gene encoding phosphomannomutase. J Biol Chem (1991) 2.20
Pak functions downstream of Dock to regulate photoreceptor axon guidance in Drosophila. Cell (1999) 2.09
Exopolysaccharides produced by Streptococcus mutans glucosyltransferases modulate the establishment of microcolonies within multispecies biofilms. J Bacteriol (2010) 2.07
Insertion of beta-satellite repeats identifies a transmembrane protease causing both congenital and childhood onset autosomal recessive deafness. Nat Genet (2001) 2.06
Functional interaction of proliferating cell nuclear antigen with MSH2-MSH6 and MSH2-MSH3 complexes. J Biol Chem (2000) 1.99
Y chromosome haplotypes reveal prehistorical migrations to the Himalayas. Hum Genet (2000) 1.95
A proposed fiber-optic scoring system to standardize the assessment of laryngeal mask airway position. Anesth Analg (1993) 1.91
Purification and characterization of phosphomannose isomerase-guanosine diphospho-D-mannose pyrophosphorylase. A bifunctional enzyme in the alginate biosynthetic pathway of Pseudomonas aeruginosa. J Biol Chem (1991) 1.78
Zn2+ promotes the self-association of human immunodeficiency virus type-1 integrase in vitro. Biochemistry (1997) 1.69
Neuropathology of cervical dystonia. Exp Neurol (2012) 1.69
Gene microarray identification of redox and mitochondrial elements that control resistance or sensitivity to apoptosis. Proc Natl Acad Sci U S A (2000) 1.60
Evidence that associated soil bacteria may influence root hair infection of actinorhizal plants by Frankia. Can J Microbiol (1980) 1.56
Direct measurement of mucosal pressures exerted by cuff and non-cuff portions of tracheal tubes with different cuff volumes and head and neck positions. Br J Anaesth (1999) 1.54
The reinforced laryngeal mask airway for laser pharyngoplasty. Anaesthesia (1993) 1.52
Peptides and genes coding for scorpion toxins that affect ion-channels. Biochimie (2000) 1.50
One year's experience with the polymerase chain reaction as a routine method for the diagnosis of imported malaria. Am J Trop Med Hyg (2002) 1.48
An alternative method for Plasmodium culture synchronization. Exp Parasitol (2005) 1.47
Short-term outcome of mechanically ventilated infants weighing more than 2499 g at birth: a population based study. J Paediatr Child Health (1993) 1.44
Cloning of the two pyruvate kinase isoenzyme structural genes from Escherichia coli: the relative roles of these enzymes in pyruvate biosynthesis. J Bacteriol (1995) 1.43
Busulphan given as four single daily doses of 150 mg/m2 is safe and effective in children of all ages. Bone Marrow Transplant (2004) 1.42
Determination of the nucleotide sequence for the glutamate synthase structural genes of Escherichia coli K-12. Gene (1987) 1.41
Cricoid pressure in chaos. Anaesthesia (1997) 1.39
Amorphous nickel hydroxide nanospheres with ultrahigh capacitance and energy density as electrochemical pseudocapacitor materials. Nat Commun (2013) 1.39
Single- compared with double-handed cricoid pressure for insertion of an LMA. Br J Anaesth (1994) 1.39
An algorithm for use of the laryngeal mask airway during failed intubation in the patient with a full stomach. Anesth Analg (1993) 1.39
The crystal structure of a class II fructose-1,6-bisphosphate aldolase shows a novel binuclear metal-binding active site embedded in a familiar fold. Structure (1996) 1.39
Use of the laryngeal mask airway to facilitate fibreoptic bronchoscopy in awake patients. Acta Anaesthesiol Scand (1994) 1.38
A challenge for clinical nurses: a new nursing role. Heart Lung (1999) 1.38
A regionalised transport service, the way ahead? Arch Dis Child (1999) 1.36
Structural and molecular basis of the role of starch and sucrose in Streptococcus mutans biofilm development. Appl Environ Microbiol (2008) 1.34
The crystal structure of Escherichia coli class II fructose-1, 6-bisphosphate aldolase in complex with phosphoglycolohydroxamate reveals details of mechanism and specificity. J Mol Biol (1999) 1.32
Comparison between two amplification sets for molecular diagnosis of toxoplasmosis by real-time PCR. J Clin Microbiol (2006) 1.32
Biochemical characterization of the cystic fibrosis transmembrane conductance regulator in normal and cystic fibrosis epithelial cells. J Biol Chem (1992) 1.31
ColE1 hybrid plasmids containing Escherichia coli genes involved in the biosynthesis of glutamate and glutamine. Plasmid (1980) 1.30
Simultaneous X-ray fluorescence and ptychographic microscopy of Cyclotella meneghiniana. Opt Express (2012) 1.29
Lack of underdominance in a naturally occurring pericentric inversion in Drosophila melanogaster and its implications for chromosome evolution. Genetics (1991) 1.28
The incidence of aspiration associated with the laryngeal mask airway: a meta-analysis of published literature. J Clin Anesth (1995) 1.27
Characterization of a site-specific restriction endonuclease SphI from Streptomyces phaeochromogenes. Gene (1980) 1.24
Diagnosis of congenital toxoplasmosis: prenatal and neonatal evaluation of methods used in Toulouse University Hospital and incidence of congenital toxoplasmosis. Mem Inst Oswaldo Cruz (2009) 1.23
Effects of the fourth chromosome on the sterility of hybrids between Drosophila simulans and its relatives. J Hered (1994) 1.21
Effect of cricoid pressure on ease of insertion of the laryngeal mask airway. Br J Anaesth (1993) 1.19
Origin of respiratory sinus arrhythmia in conscious humans. An important role for arterial carotid baroreceptors. Circulation (1997) 1.19
Early disruption of the mother-infant relationship: effects on brain plasticity and implications for psychopathology. Neurosci Biobehav Rev (2003) 1.19
Cloning, sequencing, and expression in Ficoll-generated minicells of an Escherichia coli heat-stable enterotoxin gene. Plasmid (1988) 1.18
Role of glucosyltransferase B in interactions of Candida albicans with Streptococcus mutans and with an experimental pellicle on hydroxyapatite surfaces. Appl Environ Microbiol (2011) 1.15
Characterization of sugar mixtures utilization by an Escherichia coli mutant devoid of the phosphotransferase system. Appl Microbiol Biotechnol (2001) 1.15
TBX6 null variants and a common hypomorphic allele in congenital scoliosis. N Engl J Med (2015) 1.15
Three novel mutations and twelve polymorphisms identified in the USH2A gene in Israeli USH2 families. Hum Mutat (2000) 1.15
An acidic cluster in the cytosolic domain of human cytomegalovirus glycoprotein B is a signal for endocytosis from the plasma membrane. J Virol (1999) 1.15
A family of removable cassettes designed to obtain antibiotic-resistance-free genomic modifications of Escherichia coli and other bacteria. Gene (2000) 1.14
The role of penicillin amidases in nature and in industry. Trends Biochem Sci (1991) 1.13
Caveolin mediates rapid glucocorticoid effects and couples glucocorticoid action to the antiproliferative program. Mol Endocrinol (2008) 1.13
Complete nucleotide sequence of the glutamate dehydrogenase gene from Escherichia coli K-12. Gene (1984) 1.12
Distribution of three HIV-1 resistance-conferring polymorphisms (SDF1-3'A, CCR2-641, and CCR5-delta32) in global populations. Eur J Hum Genet (2000) 1.11
A direct comparison of approaches for increasing carbon flow to aromatic biosynthesis in Escherichia coli. J Ind Microbiol (1996) 1.11
Engineering the substrate specificity of glutathione reductase toward that of trypanothione reduction. Proc Natl Acad Sci U S A (1991) 1.09
The isolation and characterization of catalytically competent porphobilinogen deaminase-intermediate complexes. FEBS Lett (1981) 1.09
Alternative techniques for laryngeal mask airway insertion. Anaesthesia (1993) 1.08
Increased beta-catenin expression and nuclear translocation accompany cellular hyperproliferation in vivo. Cancer Res (2001) 1.08
GPR54 polymorphisms in Chinese girls with central precocious puberty. Neuroendocrinology (2007) 1.08
Insertion of the laryngeal mask airway--a prospective study of four techniques. Anaesth Intensive Care (1993) 1.08
The dhnA gene of Escherichia coli encodes a class I fructose bisphosphate aldolase. Biochem J (1998) 1.08
The tissue distribution of the human beta3-adrenoceptor studied using a monoclonal antibody: direct evidence of the beta3-adrenoceptor in human adipose tissue, atrium and skeletal muscle. Int J Obes Relat Metab Disord (1999) 1.08
M2 mitochondrial antibodies and urinary rough mutant bacteria in patients with primary biliary cirrhosis and in patients with recurrent bacteriuria. J Hepatol (1993) 1.07
Y-chromosome haplotype distribution in Han Chinese populations and modern human origin in East Asians. Sci China C Life Sci (2001) 1.07