Published in Neuron on June 01, 1998
Regulation of cadherin adhesive activity. J Cell Biol (2000) 5.63
A new crystal structure, Ca2+ dependence and mutational analysis reveal molecular details of E-cadherin homoassociation. EMBO J (1999) 3.20
Single molecule imaging of green fluorescent proteins in living cells: E-cadherin forms oligomers on the free cell surface. Biophys J (2001) 3.06
Structure and biochemistry of cadherins and catenins. Cold Spring Harb Perspect Biol (2009) 2.37
Multiple cadherin extracellular repeats mediate homophilic binding and adhesion. J Cell Biol (2001) 2.09
Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation. Physiol Rev (2011) 2.06
Extracellular Ca2+ depletion contributes to fast activity-dependent modulation of synaptic transmission in the brain. Neuron (2003) 2.01
Specificity of cell-cell adhesion by classical cadherins: Critical role for low-affinity dimerization through beta-strand swapping. Proc Natl Acad Sci U S A (2005) 1.99
Cadherin-mediated cell sorting not determined by binding or adhesion specificity. J Cell Biol (2002) 1.98
Characterizing the initial encounter complex in cadherin adhesion. Structure (2009) 1.90
Two cell adhesion molecules, nectin and cadherin, interact through their cytoplasmic domain-associated proteins. J Cell Biol (2000) 1.89
Resolving cadherin interactions and binding cooperativity at the single-molecule level. Proc Natl Acad Sci U S A (2008) 1.81
Bacillus thuringiensis: a genomics and proteomics perspective. Bioeng Bugs (2011) 1.77
X-ray structure of junctional adhesion molecule: structural basis for homophilic adhesion via a novel dimerization motif. EMBO J (2001) 1.75
Proteolytic E-cadherin activation followed by solution NMR and X-ray crystallography. EMBO J (2004) 1.69
Two-step adhesive binding by classical cadherins. Nat Struct Mol Biol (2010) 1.67
N-Cadherin extracellular repeat 4 mediates epithelial to mesenchymal transition and increased motility. J Cell Biol (2000) 1.65
Direct molecular force measurements of multiple adhesive interactions between cadherin ectodomains. Proc Natl Acad Sci U S A (1999) 1.64
Molecular mechanisms of blister formation in bullous impetigo and staphylococcal scalded skin syndrome. J Clin Invest (2002) 1.64
Direct measurements of multiple adhesive alignments and unbinding trajectories between cadherin extracellular domains. Biophys J (2001) 1.58
Functional cis-heterodimers of N- and R-cadherins. J Cell Biol (2000) 1.57
Trans-bonded pairs of E-cadherin exhibit a remarkable hierarchy of mechanical strengths. Proc Natl Acad Sci U S A (2004) 1.53
Requirement of interaction of nectin-1alpha/HveC with afadin for efficient cell-cell spread of herpes simplex virus type 1. J Virol (2001) 1.46
Cadherin activity is required for activity-induced spine remodeling. J Cell Biol (2004) 1.43
Molecular interactions between desmosomal cadherins. Biochem J (2002) 1.42
The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis. Proc Natl Acad Sci U S A (2004) 1.41
Adhesive and lateral E-cadherin dimers are mediated by the same interface. Mol Cell Biol (2003) 1.37
T-cadherin structures reveal a novel adhesive binding mechanism. Nat Struct Mol Biol (2010) 1.37
Similarities between heterophilic and homophilic cadherin adhesion. Proc Natl Acad Sci U S A (2006) 1.34
The crystal structure of human E-cadherin domains 1 and 2, and comparison with other cadherins in the context of adhesion mechanism. J Mol Biol (2007) 1.32
Fast dissociation kinetics between individual E-cadherin fragments revealed by flow chamber analysis. EMBO J (2002) 1.32
Sequence and structural determinants of strand swapping in cadherin domains: do all cadherins bind through the same adhesive interface? J Mol Biol (2008) 1.31
Functional analysis of the structural basis of homophilic cadherin adhesion. Biophys J (2003) 1.31
Dynamic interplay between adhesive and lateral E-cadherin dimers. Mol Cell Biol (2002) 1.23
Molecular design principles underlying β-strand swapping in the adhesive dimerization of cadherins. Nat Struct Mol Biol (2011) 1.14
Lifetime measurements reveal kinetic differences between homophilic cadherin bonds. Biophys J (2005) 1.14
Cadherin exits the junction by switching its adhesive bond. J Cell Biol (2011) 1.12
Biophysical properties of cadherin bonds do not predict cell sorting. J Biol Chem (2008) 1.09
Wnt/frizzled-2 signaling induces aggregation and adhesion among cardiac myocytes by increased cadherin-beta-catenin complex. J Cell Biol (2000) 1.05
N-cadherin regulates ingrowth and laminar targeting of thalamocortical axons. J Neurosci (2003) 1.04
N-cadherin is an in vivo substrate for protein tyrosine phosphatase sigma (PTPsigma) and participates in PTPsigma-mediated inhibition of axon growth. Mol Cell Biol (2006) 1.01
Chromosomal protein HMGN1 modulates the expression of N-cadherin. FEBS J (2005) 1.01
Membrane-impermeable cross-linking provides evidence for homophilic, isoform-specific binding of desmosomal cadherins in epithelial cells. J Biol Chem (2010) 0.99
Calcium-dependent dynamics of cadherin interactions at cell-cell junctions. Proc Natl Acad Sci U S A (2011) 0.98
Structure of the N terminus of cadherin 23 reveals a new adhesion mechanism for a subset of cadherin superfamily members. Proc Natl Acad Sci U S A (2010) 0.98
Intercellular adhesion molecule-5 induces dendritic outgrowth by homophilic adhesion. J Cell Biol (2000) 0.98
Structural plasticity in Ig superfamily domain 4 of ICAM-1 mediates cell surface dimerization. Proc Natl Acad Sci U S A (2007) 0.96
Cross talk between focal adhesion kinase and cadherins: role in regulating endothelial barrier function. Microvasc Res (2011) 0.96
Enhancement of drug absorption through the blood-brain barrier and inhibition of intercellular tight junction resealing by E-cadherin peptides. Mol Pharm (2010) 0.95
Cadherin-mediated adhesion regulates posterior body formation. BMC Dev Biol (2007) 0.95
Molecular basis for leukocyte integrin alpha(E)beta(7) adhesion to epithelial (E)-cadherin. J Exp Med (2000) 0.94
The receptor for advanced glycation end-products (RAGE) is only present in mammals, and belongs to a family of cell adhesion molecules (CAMs). PLoS One (2014) 0.93
Dynamics and stability of E-cadherin dimers. Biophys J (2006) 0.92
Allosteric cross talk between cadherin extracellular domains. Biophys J (2010) 0.89
Nodal signaling is required for closure of the anterior neural tube in zebrafish. BMC Dev Biol (2007) 0.87
Structural and energetic determinants of adhesive binding specificity in type I cadherins. Proc Natl Acad Sci U S A (2014) 0.85
N-cadherin modulates voltage activated calcium influx via RhoA, p120-catenin, and myosin-actin interaction. Mol Cell Neurosci (2008) 0.85
N-cadherin prodomain cleavage regulates synapse formation in vivo. Dev Neurobiol (2009) 0.85
Cadherin point mutations alter cell sorting and modulate GTPase signaling. J Cell Sci (2012) 0.85
Role of N-cadherin cis and trans interfaces in the dynamics of adherens junctions in living cells. PLoS One (2013) 0.83
Differential expression of photoreceptor-specific genes in the retina of a zebrafish cadherin2 mutant glass onion and zebrafish cadherin4 morphants. Exp Eye Res (2006) 0.83
Synaptic loss and retention of different classic cadherins with LTP-associated synaptic structural remodeling in vivo. Hippocampus (2010) 0.81
Lateral assembly of N-cadherin drives tissue integrity by stabilizing adherens junctions. J R Soc Interface (2015) 0.79
N-cadherin is regulated by gonadal steroids in the adult hippocampus. Proc Natl Acad Sci U S A (2001) 0.79
Radial Glial Cell-Neuron Interaction Directs Axon Formation at the Opposite Side of the Neuron from the Contact Site. J Neurosci (2015) 0.79
Inter-cellular exchange of cellular components via VE-cadherin-dependent trans-endocytosis. PLoS One (2014) 0.78
Tuning the kinetics of cadherin adhesion. J Invest Dermatol (2013) 0.78
ADAM13 cleavage of cadherin-11 promotes CNC migration independently of the homophilic binding site. Dev Biol (2015) 0.77
Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability. Circ Res (2017) 0.76
Cadherin adhesion: mechanisms and molecular interactions. Handb Exp Pharmacol (2004) 0.76
Cadherin 2/4 signaling via PTP1B and catenins is crucial for nucleokinesis during radial neuronal migration in the neocortex. Development (2016) 0.75
Tools for studying the role of N-cadherin mediated extracellular interaction in neuronal development and function. Cell Adh Migr (2011) 0.75
IP3 receptor signaling and endothelial barrier function. Cell Mol Life Sci (2017) 0.75
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature (1998) 24.69
The antigenic structure of the HIV gp120 envelope glycoprotein. Nature (1998) 12.44
Polar location of the chemoreceptor complex in the Escherichia coli cell. Science (1993) 8.50
A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding. Science (1998) 8.36
Structural basis of cell-cell adhesion by cadherins. Nature (1995) 6.56
Crystal structure of the tyrosine kinase domain of the human insulin receptor. Nature (1995) 6.16
Structural analysis of substrate binding by the molecular chaperone DnaK. Science (1996) 6.13
Complete genome sequence of Caulobacter crescentus. Proc Natl Acad Sci U S A (2001) 5.58
In situ immunoassays for gene translation products in phage plaques and bacterial colonies. Gene (1976) 5.58
Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates. Structure (2000) 5.57
Cell cycle control by an essential bacterial two-component signal transduction protein. Cell (1996) 5.56
Checkpoints that couple gene expression to morphogenesis. Science (1993) 5.31
Stereochemically restrained refinement of macromolecular structures. Methods Enzymol (1985) 4.93
Cell type-specific phosphorylation and proteolysis of a transcriptional regulator controls the G1-to-S transition in a bacterial cell cycle. Cell (1997) 4.78
Global analysis of the genetic network controlling a bacterial cell cycle. Science (2000) 4.77
Energetics of the HIV gp120-CD4 binding reaction. Proc Natl Acad Sci U S A (2000) 4.44
The reactivity of anti-peptide antibodies is a function of the atomic mobility of sites in a protein. Nature (1984) 4.05
Studies on reovirus RNA. I. Characterization of reovirus genome RNA. J Mol Biol (1967) 3.88
Negative control of bacterial DNA replication by a cell cycle regulatory protein that binds at the chromosome origin. Proc Natl Acad Sci U S A (1998) 3.85
tmRNAs that encode proteolysis-inducing tags are found in all known bacterial genomes: A two-piece tmRNA functions in Caulobacter. Proc Natl Acad Sci U S A (2000) 3.83
Structure of ribonuclease H phased at 2 A resolution by MAD analysis of the selenomethionyl protein. Science (1990) 3.77
Circuit simulation of genetic networks. Science (1995) 3.71
The presynaptic particle web: ultrastructure, composition, dissolution, and reconstitution. Neuron (2001) 3.68
Structure of a fibronectin type III domain from tenascin phased by MAD analysis of the selenomethionyl protein. Science (1992) 3.66
Bacterial differentiation. Science (1971) 3.65
G-protein signaling through tubby proteins. Science (2001) 3.59
Cell cycle-dependent polar localization of an essential bacterial histidine kinase that controls DNA replication and cell division. Cell (1999) 3.58
Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus. J Virol (2000) 3.52
Loving openness as a meta-world hypothesis: expanding our vision of mind and medicine. Adv Mind Body Med (1999) 3.31
Synthesis and structure of Caulobacter crescentus flagella. J Bacteriol (1973) 3.28
Structure of a C-type mannose-binding protein complexed with an oligosaccharide. Nature (1992) 3.19
Requirement of the carboxyl terminus of a bacterial chemoreceptor for its targeted proteolysis. Science (1993) 2.98
Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation. Nature (1996) 2.94
Differentiation in the Caulobacter cell cycle. Annu Rev Microbiol (1976) 2.91
Differential localization of two histidine kinases controlling bacterial cell differentiation. Mol Cell (1999) 2.88
Probability analysis of variational crystallization and its application to gp120, the exterior envelope glycoprotein of type 1 human immunodeficiency virus (HIV-1). J Biol Chem (1999) 2.85
Structure of myohemerythrin in the azidomet state at 1.7/1.3 A resolution. J Mol Biol (1987) 2.79
The Caulobacter crescentus smc gene is required for cell cycle progression and chromosome segregation. Proc Natl Acad Sci U S A (1999) 2.76
Effect of dibutyryladenosine 3':5'-cyclic monophosphate on growth and differentiation in Caulobacter crescentus. Proc Natl Acad Sci U S A (1972) 2.73
Sensitivity to triazolam in the elderly. N Engl J Med (1991) 2.73
A structural superfamily of growth factors containing a cystine knot motif. Cell (1993) 2.71
Identification and cell cycle control of a novel pilus system in Caulobacter crescentus. EMBO J (2000) 2.66
A developmentally regulated Caulobacter flagellar promoter is activated by 3' enhancer and IHF binding elements. Mol Biol Cell (1992) 2.61
Structures of an MHC class II molecule with covalently bound single peptides. Science (1996) 2.58
Conferring RNA polymerase activity to a DNA polymerase: a single residue in reverse transcriptase controls substrate selection. Proc Natl Acad Sci U S A (1997) 2.54
A cell cycle-regulated bacterial DNA methyltransferase is essential for viability. Proc Natl Acad Sci U S A (1996) 2.52
Isolation and characterization of a xylose-dependent promoter from Caulobacter crescentus. J Bacteriol (1997) 2.48
The expression of asymmetry during Caulobacter cell differentiation. Annu Rev Biochem (1994) 2.46
Structure of the calcium-dependent lectin domain from a rat mannose-binding protein determined by MAD phasing. Science (1991) 2.44
Polar localization of a bacterial chemoreceptor. Genes Dev (1992) 2.39
Dimeric association and segmental variability in the structure of human CD4. Nature (1997) 2.35
Generation of a Tn5 promoter probe and its use in the study of gene expression in Caulobacter crescentus. Proc Natl Acad Sci U S A (1984) 2.34
Synthesis and incorporation of myelin polypeptides into CNS myelin. J Cell Biol (1982) 2.29
Structure-based analysis of catalysis and substrate definition in the HIT protein family. Science (1997) 2.27
Bioengineered cardiac grafts: A new approach to repair the infarcted myocardium? Circulation (2000) 2.25
Crystal structure of the extracellular domain from P0, the major structural protein of peripheral nerve myelin. Neuron (1996) 2.25
An oligodendrocyte cell adhesion molecule at the site of assembly of the paranodal axo-glial junction. J Cell Biol (2000) 2.24
A Caulobacter DNA methyltransferase that functions only in the predivisional cell. J Mol Biol (1994) 2.20
Mechanistic implications from the structure of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase. Structure (1995) 2.20
A model for central synaptic junctional complex formation based on the differential adhesive specificities of the cadherins. Neuron (1996) 2.20
Bacterial differentiation and phage infection. Virology (1971) 2.17
A temporally controlled sigma-factor is required for polar morphogenesis and normal cell division in Caulobacter. Genes Dev (1992) 2.13
Dissecting Aneurysms. Can Med Assoc J (1943) 2.13
Rapid conduction and the evolution of giant axons and myelinated fibers. Curr Biol (2007) 2.11
Characterization and crystallization of core streptavidin. J Biol Chem (1987) 2.09
Feedback control of a master bacterial cell-cycle regulator. Proc Natl Acad Sci U S A (1999) 2.08
Direct phase determination based on anomalous scattering. Methods Enzymol (1985) 2.02
Molecular modification of N-cadherin in response to synaptic activity. Neuron (2000) 2.02
The diversity of cadherins and implications for a synaptic adhesive code in the CNS. Neuron (1999) 2.00
Overview of interleukin-18: more than an interferon-gamma inducing factor. J Leukoc Biol (1998) 2.00
Genetic analysis of a temporally transcribed chemotaxis gene cluster in Caulobacter crescentus. Genetics (1991) 1.96
Dynamic localization of a cytoplasmic signal transduction response regulator controls morphogenesis during the Caulobacter cell cycle. Proc Natl Acad Sci U S A (2001) 1.95
A moving DNA replication factory in Caulobacter crescentus. EMBO J (2001) 1.94
Linking molecular affinity and cellular specificity in cadherin-mediated adhesion. Proc Natl Acad Sci U S A (2009) 1.93
A pleiotropic mutation affecting expression of polar development events in Caulobacter crescentus. Proc Natl Acad Sci U S A (1974) 1.92
Caulobacter Lon protease has a critical role in cell-cycle control of DNA methylation. Genes Dev (1996) 1.89
Cell cycle-controlled proteolysis of a flagellar motor protein that is asymmetrically distributed in the Caulobacter predivisional cell. EMBO J (1996) 1.89
The CtrA response regulator mediates temporal control of gene expression during the Caulobacter cell cycle. J Bacteriol (1999) 1.88
The lipopolysaccharide-activated toll-like receptor (TLR)-4 induces synthesis of the closely related receptor TLR-2 in adipocytes. J Biol Chem (2000) 1.87
The amino acid sequences of the myelin-associated glycoproteins: homology to the immunoglobulin gene superfamily. J Cell Biol (1987) 1.87
Differential expression and positioning of chemotaxis methylation proteins in Caulobacter. J Mol Biol (1984) 1.87
Structure of human chorionic gonadotropin at 2.6 A resolution from MAD analysis of the selenomethionyl protein. Structure (1994) 1.87
Bacterial DNA methylation: a cell cycle regulator? J Bacteriol (1999) 1.84
Identification of a Caulobacter crescentus operon encoding hrcA, involved in negatively regulating heat-inducible transcription, and the chaperone gene grpE. J Bacteriol (1996) 1.83
Membrane phospholipid composition of Caulobacter crescentus. J Bacteriol (1978) 1.82
Stalked bacteria: properties of deoxriybonucleic acid bacteriophage phiCbK. J Virol (1970) 1.80
A randomized, controlled trial of IL-10 in humans. Inhibition of inflammatory cytokine production and immune responses. J Immunol (1995) 1.76
The CcrM DNA methyltransferase is widespread in the alpha subdivision of proteobacteria, and its essential functions are conserved in Rhizobium meliloti and Caulobacter crescentus. J Bacteriol (1997) 1.76
Interleukin-1 induces interleukin-8 secretion from endothelial cells by a juxtacrine mechanism. Blood (1994) 1.76
Structural interactions of fibroblast growth factor receptor with its ligands. Proc Natl Acad Sci U S A (2000) 1.76
The Brucella abortus CcrM DNA methyltransferase is essential for viability, and its overexpression attenuates intracellular replication in murine macrophages. J Bacteriol (2000) 1.75
Expression of the Caulobacter heat shock gene dnaK is developmentally controlled during growth at normal temperatures. J Bacteriol (1990) 1.74
Cell-cycle control of a cloned chromosomal origin of replication from Caulobacter crescentus. J Mol Biol (1992) 1.73
Crystal structure of a functional unit from Octopus hemocyanin. J Mol Biol (1998) 1.71