Published in Biochemistry on July 21, 1998
Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active mechanism. EMBO J (2000) 2.27
A nonuniform stepping mechanism for E. coli UvrD monomer translocation along single-stranded DNA. Mol Cell (2007) 2.00
The efficiency of contraction in rabbit skeletal muscle fibres, determined from the rate of release of inorganic phosphate. J Physiol (1999) 1.48
ATP consumption and efficiency of human single muscle fibers with different myosin isoform composition. Biophys J (2000) 1.45
Defining the roles of individual residues in the single-stranded DNA binding site of PcrA helicase. Proc Natl Acad Sci U S A (2001) 1.35
Active site opening and closure control translocation of multisubunit RNA polymerase. Nucleic Acids Res (2012) 1.27
Duplex unwinding and ATPase activities of the DEAD-box helicase eIF4A are coupled by eIF4G and eIF4B. J Mol Biol (2011) 1.25
The effects of nucleotides on MutS-DNA binding kinetics clarify the role of MutS ATPase activity in mismatch repair. J Mol Biol (2006) 1.25
Asymmetric ATP binding and hydrolysis activity of the Thermus aquaticus MutS dimer is key to modulation of its interactions with mismatched DNA. Biochemistry (2004) 1.24
PcrA helicase tightly couples ATP hydrolysis to unwinding double-stranded DNA, modulated by the initiator protein for plasmid replication, RepD. Biochemistry (2009) 1.17
Fluorescent single-stranded DNA binding protein as a probe for sensitive, real-time assays of helicase activity. Biophys J (2008) 1.11
Setting the chaperonin timer: the effects of K+ and substrate protein on ATP hydrolysis. Proc Natl Acad Sci U S A (2008) 1.11
Glu257 in GroEL is a sensor involved in coupling polypeptide substrate binding to stimulation of ATP hydrolysis. Protein Sci (2006) 1.10
Fluorescent coumarin-labeled nucleotides to measure ADP release from actomyosin. Biophys J (2001) 1.08
The protease domain increases the translocation stepping efficiency of the hepatitis C virus NS3-4A helicase. J Biol Chem (2010) 1.06
Kinetic analysis of correct nucleotide insertion by a Y-family DNA polymerase reveals conformational changes both prior to and following phosphodiester bond formation as detected by tryptophan fluorescence. J Biol Chem (2008) 1.06
Mechanism of ATP-driven PCNA clamp loading by S. cerevisiae RFC. J Mol Biol (2009) 1.04
Analysis of allosteric signal transduction mechanisms in an engineered fluorescent maltose biosensor. Protein Sci (2005) 0.99
A biosensor for fluorescent determination of ADP with high time resolution. J Biol Chem (2009) 0.98
Analysis of ligand binding to a ribose biosensor using site-directed mutagenesis and fluorescence spectroscopy. Protein Sci (2007) 0.98
A continuous enzyme-coupled assay for triphosphohydrolase activity of HIV-1 restriction factor SAMHD1. Antimicrob Agents Chemother (2014) 0.97
Real-time measurement of pyrophosphate release kinetics. Anal Biochem (2007) 0.96
Substrate protein switches GroE chaperonins from asymmetric to symmetric cycling by catalyzing nucleotide exchange. Proc Natl Acad Sci U S A (2013) 0.95
Mechanisms of protein-ligand association and its modulation by protein mutations. Biophys J (2011) 0.94
Effect of strain on actomyosin kinetics in isometric muscle fibers. Biophys J (2006) 0.93
Impact of individual proliferating cell nuclear antigen-DNA contacts on clamp loading and function on DNA. J Biol Chem (2012) 0.92
Strand and nucleotide-dependent ATPase activity of gp16 of bacterial virus phi29 DNA packaging motor. Virology (2008) 0.92
A rotor-stator cross-link in the F1-ATPase blocks the rate-limiting step of rotational catalysis. J Biol Chem (2008) 0.92
Role of a conserved glutamate residue in the Escherichia coli SecA ATPase mechanism. J Biol Chem (2005) 0.92
Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction. PLoS Pathog (2015) 0.91
Crystal structure of a GroEL-ADP complex in the relaxed allosteric state at 2.7 Å resolution. Proc Natl Acad Sci U S A (2013) 0.90
A fluorescent, reagentless biosensor for ADP based on tetramethylrhodamine-labeled ParM. ACS Chem Biol (2010) 0.88
Design strategies of fluorescent biosensors based on biological macromolecular receptors. Sensors (Basel) (2010) 0.88
Efficient coupling of ATP hydrolysis to translocation by RecQ helicase. Proc Natl Acad Sci U S A (2012) 0.88
Time course and strain dependence of ADP release during contraction of permeabilized skeletal muscle fibers. Biophys J (2009) 0.88
ATP binding and hydrolysis-driven rate-determining events in the RFC-catalyzed PCNA clamp loading reaction. J Mol Biol (2011) 0.87
A central swivel point in the RFC clamp loader controls PCNA opening and loading on DNA. J Mol Biol (2011) 0.87
The β sliding clamp closes around DNA prior to release by the Escherichia coli clamp loader γ complex. J Biol Chem (2012) 0.85
Fluorescent labeling and modification of proteins. J Chem Biol (2013) 0.85
Mechanism of cadmium-mediated inhibition of Msh2-Msh6 function in DNA mismatch repair. Biochemistry (2009) 0.85
The primary and secondary translocase activities within E. coli RecBC helicase are tightly coupled to ATP hydrolysis by the RecB motor. J Mol Biol (2012) 0.85
Elucidation of kinetic mechanisms of human translesion DNA polymerase κ using tryptophan mutants. FEBS J (2014) 0.85
Recombination hotspots attenuate the coupled ATPase and translocase activities of an AddAB-type helicase-nuclease. Nucleic Acids Res (2014) 0.84
Influence of ionic strength on the time course of force development and phosphate release by dogfish muscle fibres. J Physiol (2005) 0.84
Conserved residues in the delta subunit help the E. coli clamp loader, gamma complex, target primer-template DNA for clamp assembly. Nucleic Acids Res (2008) 0.84
Monomeric PcrA helicase processively unwinds plasmid lengths of DNA in the presence of the initiator protein RepD. Nucleic Acids Res (2013) 0.83
The MitCHAP-60 disease is due to entropic destabilization of the human mitochondrial Hsp60 oligomer. J Biol Chem (2009) 0.83
DNA polymerase V activity is autoregulated by a novel intrinsic DNA-dependent ATPase. Elife (2014) 0.82
ATPase cycle and DNA unwinding kinetics of RecG helicase. PLoS One (2012) 0.82
Design, total chemical synthesis, and binding properties of a [Leu-91-N1-methyl-7-azaTrp]Ras-binding domain of c-Raf-1. Proc Natl Acad Sci U S A (1999) 0.82
Time-resolved measurements of phosphate release by cycling cross-bridges in portal vein smooth muscle. Biophys J (1998) 0.82
Real-time fluorescence assays to monitor duplex unwinding and ATPase activities of helicases. Nat Protoc (2014) 0.82
ATPase mechanism of the 5'-3' DNA helicase, RecD2: evidence for a pre-hydrolysis conformation change. J Biol Chem (2013) 0.81
The rapid and direct determination of ATPase activity by ion exchange chromatography and the application to the activity of heat shock protein-90. J Pharm Biomed Anal (2012) 0.81
A continuous fluorescence assay for the characterization of Nudix hydrolases. Anal Biochem (2013) 0.77
Pi Release Limits the Intrinsic and RNA-Stimulated ATPase Cycles of DEAD-Box Protein 5 (Dbp5). J Mol Biol (2015) 0.77
ADP but not P(i) dissociation contributes to rate limitation for Escherichia coli Rho. J Biol Chem (2009) 0.76
Development of a Reagentless Biosensor for Inorganic Phosphate, Applicable over a Wide Concentration Range. Biochemistry (2015) 0.76
Immobilization of NTPDase-1 from Trypanosoma cruzi and Development of an Online Label-Free Assay. J Anal Methods Chem (2016) 0.75
A continuous spectrophotometric enzyme-coupled assay for deoxynucleoside triphosphate triphosphohydrolases. Anal Biochem (2015) 0.75
Rad51 Nucleoprotein Filament Disassembly Captured Using Fluorescent Plasmodium falciparum SSB as a Reporter for Single-Stranded DNA. PLoS One (2016) 0.75
Application of stopped-flow kinetics methods to investigate the mechanism of action of a DNA repair protein. J Vis Exp (2010) 0.75
Substrate specificity characterization for eight putative nudix hydrolases. Evaluation of criteria for substrate identification within the Nudix family. Proteins (2016) 0.75
Linchpin DNA-binding residues serve as go/no-go controls in the replication factor C-catalyzed clamp loading mechanism. J Biol Chem (2017) 0.75
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5. Nature (1996) 20.59
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell (1996) 17.81
Changes in the conformation of influenza virus hemagglutinin at the pH optimum of virus-mediated membrane fusion. Proc Natl Acad Sci U S A (1982) 7.34
Direct, real-time measurement of rapid inorganic phosphate release using a novel fluorescent probe and its application to actomyosin subfragment 1 ATPase. Biochemistry (1994) 4.97
Customized growth curves for identification of large-for-gestational age neonates in pre-eclamptic women. Ultrasound Obstet Gynecol (2014) 4.86
Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposure. Nat Med (1996) 4.57
Pathway of processive ATP hydrolysis by kinesin. Nature (1995) 3.46
Tilting of the light-chain region of myosin during step length changes and active force generation in skeletal muscle. Nature (1995) 3.34
Demonstration of unidirectional single-stranded DNA translocation by PcrA helicase: measurement of step size and translocation speed. Biochemistry (2000) 2.82
Real time imaging of single fluorophores on moving actin with an epifluorescence microscope. Biophys J (1995) 2.57
Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes. EMBO J (2001) 2.34
Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active mechanism. EMBO J (2000) 2.27
Kinetics of nucleoside triphosphate cleavage and phosphate release steps by associated rabbit skeletal actomyosin, measured using a novel fluorescent probe for phosphate. Biochemistry (1997) 2.23
Studies on the structure of the influenza virus haemagglutinin at the pH of membrane fusion. J Gen Virol (1988) 2.21
Nonaccidental poisoning in childhood. Arch Dis Child (1979) 2.15
Conformational changes in the hemagglutinin of influenza virus which accompany heat-induced fusion of virus with liposomes. Virology (1986) 2.13
Evidence for a repeating cross-beta sheet structure in the adenovirus fibre. EMBO J (1983) 2.09
Rapid urea hydrolysis by gastric Campylobacters. Lancet (1985) 2.06
Photochemical and pharmacological evaluation of 7-nitroindolinyl-and 4-methoxy-7-nitroindolinyl-amino acids as novel, fast caged neurotransmitters. J Neurosci Methods (2001) 2.02
Accuracy of decrease in blood flow in predicting hemodialysis graft thrombosis. Am J Kidney Dis (2000) 1.93
Xanthophyll cycle-dependent quenching of photosystem II chlorophyll a fluorescence: formation of a quenching complex with a short fluorescence lifetime. Proc Natl Acad Sci U S A (1995) 1.93
Oxygen exchange between Pi in the medium and water during ATP hydrolysis mediated by skinned fibers from rabbit skeletal muscle. Evidence for Pi binding to a force-generating state. J Biol Chem (1986) 1.89
ATPase kinetics on activation of rabbit and frog permeabilized isometric muscle fibres: a real time phosphate assay. J Physiol (1997) 1.88
Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Nature (2000) 1.85
Microtubule dynamic instability: numerical simulation of microtubule transition properties using a Lateral Cap model. J Cell Sci (1990) 1.84
Kinetics of relaxation from rigor of permeabilized fast-twitch skeletal fibers from the rabbit using a novel caged ATP and apyrase. Biophys J (1994) 1.78
Fluorescence polarization transients from rhodamine isomers on the myosin regulatory light chain in skeletal muscle fibers. Biophys J (1998) 1.75
Target recognition by calmodulin: dissecting the kinetics and affinity of interaction using short peptide sequences. Protein Sci (1996) 1.73
Membrane fusion by peptide analogues of influenza virus haemagglutinin. J Gen Virol (1988) 1.69
The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue. Nat Struct Biol (1997) 1.58
Experimental autoimmune renal disease in rats. Ann N Y Acad Sci (1965) 1.57
Activation of NADPH oxidase involves the dissociation of p21rac from its inhibitory GDP/GTP exchange protein (rhoGDI) followed by its translocation to the plasma membrane. Biochem J (1994) 1.55
Alpha-helix in the carboxy-terminal domains of histones H1 and H5. EMBO J (1988) 1.55
The efficiency of contraction in rabbit skeletal muscle fibres, determined from the rate of release of inorganic phosphate. J Physiol (1999) 1.48
Meiotic analysis of a pericentric inversion, inv(7) (p22q32), in the father of a child with a duplication-deletion of chromosome 7. Cytogenet Cell Genet (1978) 1.48
Syndrome of apparent mineralocorticoid excess. A defect in the cortisol-cortisone shuttle. J Clin Invest (1988) 1.44
Ligand binding and thermodynamic stability of a multidomain protein, calmodulin. Protein Sci (2000) 1.42
The kinetics of calcium binding to calmodulin: Quin 2 and ANS stopped-flow fluorescence studies. Biochem Biophys Res Commun (1984) 1.41
Quantitative analysis of the effects of intrathylakoid pH and xanthophyll cycle pigments on chlorophyll a fluorescence lifetime distributions and intensity in thylakoids. Biochemistry (1998) 1.40
In vivo and in vitro characterization of the B1 and B2 zinc-binding domains from the acute promyelocytic leukemia protooncoprotein PML. Proc Natl Acad Sci U S A (1996) 1.39
Substitutional and insertional RNA editing of the cytochrome c oxidase subunit 1 mRNA of Physarum polycephalum. J Biol Chem (1993) 1.38
Rapid differentiation of closely related Candida species and strains by pyrolysis-mass spectrometry and Fourier transform-infrared spectroscopy. J Clin Microbiol (1998) 1.36
Defining the roles of individual residues in the single-stranded DNA binding site of PcrA helicase. Proc Natl Acad Sci U S A (2001) 1.35
Structural basis for oseltamivir resistance of influenza viruses. Vaccine (2009) 1.31
The mechanism of guanosine nucleotide hydrolysis by p21 c-Ha-ras. The stereochemical course of the GTPase reaction. J Biol Chem (1989) 1.30
Conformational flexibility and folding of synthetic peptides representing an interdomain segment of polypeptide chain in the pyruvate dehydrogenase multienzyme complex of Escherichia coli. J Biol Chem (1989) 1.29
Biosynthesis of terpenes and steroids. IX. The sterols of some mutant yeasts and their relationship to the biosynthesis of ergosterol. J Chem Soc Perkin 1 (1974) 1.26
Kinetic analysis of the hydrolysis of GTP by p21N-ras. The basal GTPase mechanism. J Biol Chem (1988) 1.23
Kinetics of calcium dissociation from calmodulin and its tryptic fragments. A stopped-flow fluorescence study using Quin 2 reveals a two-domain structure. Eur J Biochem (1985) 1.23
Hydrolysis of GTP by p21NRAS, the NRAS protooncogene product, is accompanied by a conformational change in the wild-type protein: use of a single fluorescent probe at the catalytic site. Proc Natl Acad Sci U S A (1990) 1.22
Ca2+ coordination to backbone carbonyl oxygen atoms in calmodulin and other EF-hand proteins: 15N chemical shifts as probes for monitoring individual-site Ca2+ coordination. Biochemistry (1998) 1.20
The conductance underlying the parallel fibre slow EPSP in rat cerebellar Purkinje neurones studied with photolytic release of L-glutamate. J Physiol (2001) 1.20
Oxygen exchange between phosphate and water accompanies calcium-regulated ATPase activity of skinned fibers from rabbit skeletal muscle. J Biol Chem (1985) 1.20
Sterol mutants of Saccharomyces cerevisiae: chromatographic analyses. Lipids (1977) 1.20
A simple formulation of microtubule dynamics: quantitative implications of the dynamic instability of microtubule populations in vivo and in vitro. J Cell Sci (1989) 1.20
Novel topology of a zinc-binding domain from a protein involved in regulating early Xenopus development. EMBO J (1995) 1.18
Interaction between chloramphenicol and acetaminophen. Arch Dis Child (1986) 1.17
Comparative single-molecule and ensemble myosin enzymology: sulfoindocyanine ATP and ADP derivatives. Biophys J (2000) 1.17
Changes in the ATPase activity of insect fibrillar flight muscle during calcium and strain activation probed by phosphate-water oxygen exchange. J Biol Chem (1987) 1.17
Fluorescence polarization of skeletal muscle fibers labeled with rhodamine isomers on the myosin heavy chain. Biophys J (1996) 1.17
Steady-state fluorescence polarization studies of the orientation of myosin regulatory light chains in single skeletal muscle fibers using pure isomers of iodoacetamidotetramethylrhodamine. Biophys J (1998) 1.14
Deficient L-ornithine: 2-oxoacid aminotransferase activity in cultured fibroblasts from a patient with gyrate atrophy of the retina. Biochem Biophys Res Commun (1977) 1.14
Expression and structural analysis of 14-3-3 proteins. J Mol Biol (1995) 1.11
Conformational aspects of the acid-induced fusion mechanism of influenza virus hemagglutinin. Circular dichroism and fluorescence studies. J Biol Chem (1988) 1.11
Conformation and assembly characteristics of tubulin and microtubule protein from bovine brain. Biochemistry (1981) 1.10
Kinetic control of the dissociation pathway of calmodulin-peptide complexes. J Biol Chem (1997) 1.10
BRCT domain interactions in the heterodimeric DNA repair protein XRCC1-DNA ligase III. Biochemistry (2001) 1.10
Solution conformation of a deoxynucleotide containing tandem G.A mismatched base pairs and 3'-overhanging ends in d(GTGAACTT)2. Biochemistry (1992) 1.09
X-ray crystal structure analysis of the catalytic domain of the oncogene product p21H-ras complexed with caged GTP and mant dGppNHp. J Mol Biol (1995) 1.09
Gyrate atrophy of the retina: inborn error of L-ornithin:2-oxoacid aminotransferase. Science (1978) 1.08
Fluorescent coumarin-labeled nucleotides to measure ADP release from actomyosin. Biophys J (2001) 1.08
Crystal structure of phosphate binding protein labeled with a coumarin fluorophore, a probe for inorganic phosphate. Biochemistry (1998) 1.08
Elucidation of a PTS-carbohydrate chemotactic signal pathway in Escherichia coli using a time-resolved behavioral assay. Mol Biol Cell (1999) 1.07
The N-terminus of the fragile X mental retardation protein contains a novel domain involved in dimerization and RNA binding. Biochemistry (2003) 1.07
Time resolved measurements show that phosphate release is the rate limiting step on myofibrillar ATPases. FEBS Lett (1995) 1.06
Early assessment of gestation in diabetics. Lancet (1984) 1.06
Phosphate release during microtubule assembly: what stabilizes growing microtubules? Biochemistry (1999) 1.05
Requirements for chromatin modulation and transcription activation by the Pho4 acidic activation domain. Mol Cell Biol (1998) 1.05
A stable alpha-helical element in the carboxy-terminal domain of free and chromatin-bound histone H1 from sea urchin sperm. EMBO J (1989) 1.04
ATPase and shortening rates in frog fast skeletal myofibrils by time-resolved measurements of protein-bound and free Pi. Biophys J (1998) 1.04
Interaction of GTPase activating proteins (GAPs) with p21ras measured by a novel fluorescence anisotropy method. Essential role of Arg-903 of GAP in activation of GTP hydrolysis on p21ras. J Biol Chem (1993) 1.04
Techniques for investigation of an apparent outbreak of infections with Candida glabrata. J Clin Microbiol (1996) 1.02
Structural organization of the N-terminal domain of apolipoprotein A-I: studies of tryptophan mutants. Biochemistry (1999) 1.02
Vibrational study of phosphate modes in GDP and GTP and their interaction with magnesium in aqueous solution. Biospectroscopy (1998) 1.02
Mechanism of GTP hydrolysis by p21N-ras catalyzed by GAP: studies with a fluorescent GTP analogue. Biochemistry (1993) 1.02
A kinetic analysis of the nucleotide-induced allosteric transitions of GroEL. J Mol Biol (1999) 1.02
Circular dichroism studies on calcium binding to two series of Ca2+ binding site mutants of Drosophila melanogaster calmodulin. Biochemistry (1992) 1.00
Restriction fragment length polymorphism analysis of azole-resistant and azole-susceptible Candida albicans strains. J Clin Microbiol (1991) 1.00
On the relationship between nucleotide hydrolysis and microtubule assembly: studies with a GTP-regenerating system. Biochem Biophys Res Commun (1987) 1.00
Regulation of microtubule dynamic instability by tubulin-GDP. Biochemistry (1995) 0.99
The hydrolysis of ATP that accompanies actin polymerization is essentially irreversible. FEBS Lett (1988) 0.99
Malnutrition and carbohydrate malabsorption in children with vertically transmitted human immunodeficiency virus 1 infection. Gastroenterology (1991) 0.99