Published in Genes Dev on October 01, 1998
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Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices. J Cell Biol (2007) 2.17
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MDM2 promotes p21waf1/cip1 proteasomal turnover independently of ubiquitylation. EMBO J (2003) 2.13
Nucleophosmin is required for DNA integrity and p19Arf protein stability. Mol Cell Biol (2005) 2.10
Hypoxia links ATR and p53 through replication arrest. Mol Cell Biol (2002) 2.03
Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21(Waf1/Cip1). Mol Cell Biol (2006) 2.02
DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53. Proc Natl Acad Sci U S A (2001) 2.00
p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling. J Cell Biol (2005) 1.86
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A role for p53 in base excision repair. EMBO J (2001) 1.56
p53 accumulates but is functionally impaired when DNA synthesis is blocked. Proc Natl Acad Sci U S A (2001) 1.55
Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress. Mol Cell Biol (2001) 1.54
p53 regulates FAK expression in human tumor cells. Mol Carcinog (2008) 1.52
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ZBP-89 promotes growth arrest through stabilization of p53. Mol Cell Biol (2001) 1.43
Sensing of intermediates in V(D)J recombination by ATM. Genes Dev (2002) 1.42
Cell cycle inhibition by the anti-angiogenic agent TNP-470 is mediated by p53 and p21WAF1/CIP1. Proc Natl Acad Sci U S A (2000) 1.39
ARF function does not require p53 stabilization or Mdm2 relocalization. Mol Cell Biol (2002) 1.39
Identification of nucleolin and nucleophosmin as genotoxic stress-responsive RNA-binding proteins. Nucleic Acids Res (2002) 1.37
Rapid activation of G2/M checkpoint after hypertonic stress in renal inner medullary epithelial (IME) cells is protective and requires p38 kinase. Proc Natl Acad Sci U S A (2001) 1.36
Caveolin-1 regulates the antagonistic pleiotropic properties of cellular senescence through a novel Mdm2/p53-mediated pathway. Cancer Res (2009) 1.36
FAK overexpression and p53 mutations are highly correlated in human breast cancer. Int J Cancer (2009) 1.35
Atm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous system. Proc Natl Acad Sci U S A (2000) 1.35
Double-stranded-RNA-activated protein kinase PKR enhances transcriptional activation by tumor suppressor p53. Mol Cell Biol (1999) 1.34
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Caveolin 1-mediated regulation of receptor tyrosine kinase-associated phosphatidylinositol 3-kinase activity by ceramide. Mol Cell Biol (2000) 1.27
Targeting p53 for Novel Anticancer Therapy. Transl Oncol (2010) 1.26
Inactivation of p53 by human T-cell lymphotropic virus type 1 Tax requires activation of the NF-kappaB pathway and is dependent on p53 phosphorylation. Mol Cell Biol (2000) 1.26
Suppression of the STK15 oncogenic activity requires a transactivation-independent p53 function. EMBO J (2002) 1.25
Functional analysis of p53 binding under differential stresses. Mol Cell Biol (2006) 1.25
Zerumbone induced apoptosis in liver cancer cells via modulation of Bax/Bcl-2 ratio. Cancer Cell Int (2007) 1.25
Hepatitis B virus X protein via the p38MAPK pathway induces E2F1 release and ATR kinase activation mediating p53 apoptosis. J Biol Chem (2008) 1.23
hADA3 is required for p53 activity. EMBO J (2001) 1.22
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