Published in Mol Cell Biol on April 01, 2004
The E2F family: specific functions and overlapping interests. EMBO J (2004) 3.33
An E2F1-dependent gene expression program that determines the balance between proliferation and cell death. Cancer Cell (2008) 3.07
p53 and E2f: partners in life and death. Nat Rev Cancer (2009) 3.06
Life and death decisions by the E2F transcription factors. Curr Opin Cell Biol (2007) 2.66
Human papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiation. PLoS Pathog (2009) 2.21
Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim. Proc Natl Acad Sci U S A (2005) 2.07
The RB-E2F1 pathway regulates autophagy. Cancer Res (2010) 1.90
Taking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response. DNA Repair (Amst) (2009) 1.89
miR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progression. Oncogene (2008) 1.86
ATM promotes apoptosis and suppresses tumorigenesis in response to Myc. Proc Natl Acad Sci U S A (2006) 1.58
E2F1 is crucial for E2F-dependent apoptosis. EMBO Rep (2005) 1.51
Human papillomaviruses recruit cellular DNA repair and homologous recombination factors to viral replication centers. J Virol (2012) 1.37
Balancing the decision of cell proliferation and cell fate. Cell Cycle (2009) 1.36
Opposing roles of E2Fs in cell proliferation and death. Cancer Biol Ther (2004) 1.33
Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage. Mol Cell (2008) 1.30
E2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone methyltransferases. EMBO J (2009) 1.28
Hepatitis B virus X protein via the p38MAPK pathway induces E2F1 release and ATR kinase activation mediating p53 apoptosis. J Biol Chem (2008) 1.23
ATM-mediated transcriptional and developmental responses to gamma-rays in Arabidopsis. PLoS One (2007) 1.20
Jab1 is a specificity factor for E2F1-induced apoptosis. Genes Dev (2006) 1.17
Human papillomavirus (HPV) E7 induces prolonged G2 following S phase reentry in differentiated human keratinocytes. J Biol Chem (2011) 1.11
DNA damage-induced cell cycle regulation and function of novel Chk2 phosphoresidues. Mol Cell Biol (2006) 1.07
An E2F1-mediated DNA damage response contributes to the replication of human cytomegalovirus. PLoS Pathog (2011) 1.04
Human cytomegalovirus IE1-72 activates ataxia telangiectasia mutated kinase and a p53/p21-mediated growth arrest response. J Virol (2005) 1.04
A combinatorial mechanism for determining the specificity of E2F activation and repression. Oncogene (2009) 0.94
E2F6 inhibits cobalt chloride-mimetic hypoxia-induced apoptosis through E2F1. Mol Biol Cell (2008) 0.92
The DNA damage response in viral-induced cellular transformation. Br J Cancer (2012) 0.92
E2f2 induces cone photoreceptor apoptosis independent of E2f1 and E2f3. Cell Death Differ (2013) 0.92
Molecular evidence of stress-induced acute heart injury in a mouse model simulating posttraumatic stress disorder. Proc Natl Acad Sci U S A (2014) 0.92
Manipulation of cellular DNA damage repair machinery facilitates propagation of human papillomaviruses. Semin Cancer Biol (2014) 0.90
The Role of the DNA Damage Response throughout the Papillomavirus Life Cycle. Viruses (2015) 0.89
Site-specific programming of the host epithelial transcriptome by the gut microbiota. Genome Biol (2015) 0.88
Regulation of the life cycle of HPVs by differentiation and the DNA damage response. Future Microbiol (2013) 0.87
Cataloging and organizing p73 interactions in cell cycle arrest and apoptosis. Nucleic Acids Res (2008) 0.86
Human papillomavirus E7 induces rereplication in response to DNA damage. J Virol (2012) 0.85
A transcriptionally active pRb-E2F1-P/CAF signaling pathway is central to TGFβ-mediated apoptosis. Cell Death Dis (2012) 0.85
Role of Cdk1 in DNA damage-induced G1 checkpoint abrogation by the human papillomavirus E7 oncogene. Cell Cycle (2014) 0.82
The role of the E2F transcription factor family in UV-induced apoptosis. Int J Mol Sci (2011) 0.81
The Rb binding domain of HPV31 E7 is required to maintain high levels of DNA repair factors in infected cells. Virology (2016) 0.79
Genomic Instability and Cancer. J Carcinog Mutagen (2014) 0.76
Targeting the retinoblastoma protein by MC007L, gene product of the molluscum contagiosum virus: detection of a novel virus-cell interaction by a member of the poxviruses. J Virol (2008) 0.76
Selective tumor killing based on specific DNA-damage response deficiencies. Cancer Biol Ther (2012) 0.76
Cell cycle regulatory protein expression profiles by adenovirus p53 infection in human papilloma virus-associated cervical cancer cells. Cancer Res Treat (2006) 0.75
A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci U S A (1998) 24.58
Mdm2 promotes the rapid degradation of p53. Nature (1997) 21.26
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature (2003) 20.13
Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev (2001) 12.46
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF. Cell (1997) 12.41
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science (1998) 11.90
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett (1997) 11.19
Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science (1998) 10.89
E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints. Genes Dev (2002) 10.06
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science (1998) 8.74
Signaling to p53: breaking the MDM2-p53 circuit. Cell (1998) 8.63
DNA damage-induced activation of p53 by the checkpoint kinase Chk2. Science (2000) 7.85
The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev (1998) 7.46
ATR disruption leads to chromosomal fragmentation and early embryonic lethality. Genes Dev (2000) 7.28
Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature (1993) 6.84
Substrate specificities and identification of putative substrates of ATM kinase family members. J Biol Chem (1999) 6.14
E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis. Genes Dev (2001) 6.13
Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. Genes Dev (1993) 6.02
The Rb/E2F pathway: expanding roles and emerging paradigms. Genes Dev (2000) 5.93
Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53. Genes Dev (2000) 5.90
Distinct roles for E2F proteins in cell growth control and apoptosis. Proc Natl Acad Sci U S A (1997) 5.83
DNA damage induces phosphorylation of the amino terminus of p53. Genes Dev (1997) 5.76
The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev (2000) 5.72
Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro. Proc Natl Acad Sci U S A (2000) 5.64
Use of chromatin immunoprecipitation to clone novel E2F target promoters. Mol Cell Biol (2001) 5.61
ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway. Nature (2000) 5.55
p53 and E2F-1 cooperate to mediate apoptosis. Proc Natl Acad Sci U S A (1994) 5.49
The many substrates and functions of ATM. Nat Rev Mol Cell Biol (2000) 5.46
Post-translational modifications and activation of p53 by genotoxic stresses. Eur J Biochem (2001) 5.43
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc Natl Acad Sci U S A (1994) 5.11
Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. Mol Cell Biol (2001) 5.03
p14ARF links the tumour suppressors RB and p53. Nature (1998) 4.78
p53: death star. Cell (2000) 4.77
Mediation of c-Myc-induced apoptosis by p53. Science (1994) 4.45
Toward an understanding of the functional complexity of the E2F and retinoblastoma families. Cell Growth Differ (1998) 4.38
ATM and ATR: networking cellular responses to DNA damage. Curr Opin Genet Dev (2001) 4.05
Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6. Mol Cell Biol (1998) 3.99
Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products. Nature (2000) 3.96
Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts. Genes Dev (2000) 3.96
E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. J Virol (1995) 3.55
Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription. EMBO J (2002) 3.45
Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation. Genes Dev (2001) 3.41
Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice. Curr Biol (2000) 3.34
Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway. Oncogene (1999) 3.23
The p53 network. J Biol Chem (1998) 3.19
Chk2 activates E2F-1 in response to DNA damage. Nat Cell Biol (2003) 3.12
Direct coupling of the cell cycle and cell death machinery by E2F. Nat Cell Biol (2002) 3.00
Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system. Science (1998) 2.88
ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation. Proc Natl Acad Sci U S A (2001) 2.75
Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1. Nat Cell Biol (2000) 2.66
Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system. EMBO J (1996) 2.63
The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53. Mol Cell Biol (1998) 2.53
A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage. Proc Natl Acad Sci U S A (1999) 2.51
The p53 functional circuit. J Cell Sci (2001) 2.46
The E2F transcription factors: key regulators of cell proliferation. Biochim Biophys Acta (2000) 2.34
ATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK. Oncogene (1999) 2.30
Myc requires distinct E2F activities to induce S phase and apoptosis. Mol Cell (2001) 2.29
Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint. Curr Biol (2001) 2.20
The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability. Cancer Res (2002) 2.16
DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis. Mutat Res (2002) 2.13
Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors. Mol Cell (1998) 2.02
E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2. Cell Growth Differ (1998) 1.96
Mdm2 association with p53 targets its ubiquitination. Oncogene (1998) 1.94
Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53. Mol Cell Biol (1999) 1.94
Chk2 activation dependence on Nbs1 after DNA damage. Mol Cell Biol (2001) 1.85
Expression of the E2F1 transcription factor overcomes type beta transforming growth factor-mediated growth suppression. Proc Natl Acad Sci U S A (1995) 1.81
Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways. Nat Genet (1997) 1.76
Plk3 functionally links DNA damage to cell cycle arrest and apoptosis at least in part via the p53 pathway. J Biol Chem (2001) 1.66
Induction of ARF tumor suppressor gene expression and cell cycle arrest by transcription factor DMP1. Proc Natl Acad Sci U S A (1999) 1.65
Role of human cytomegalovirus immediate-early proteins in cell growth control. J Virol (2000) 1.48
Expression analysis using DNA microarrays demonstrates that E2F-1 up-regulates expression of DNA replication genes including replication protein A2. Oncogene (2001) 1.48
Gene expression changes in response to E2F1 activation. Nucleic Acids Res (2002) 1.44
The ataxia-telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53. Oncogene (1999) 1.41
Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53. Proc Natl Acad Sci U S A (1998) 1.38
ARF is not required for apoptosis in Rb mutant mouse embryos. Curr Biol (2002) 1.30
E2F1 induces phosphorylation of p53 that is coincident with p53 accumulation and apoptosis. Mol Cell Biol (2002) 1.30
Chk2 is dispensable for p53-mediated G1 arrest but is required for a latent p53-mediated apoptotic response. Proc Natl Acad Sci U S A (2002) 1.28
Regulation of the Chk2 protein kinase by oligomerization-mediated cis- and trans-phosphorylation. Mol Cancer Res (2003) 1.28
Identification of novel E2F1-regulated genes by microarray. Arch Biochem Biophys (2002) 1.23
E2F-1 induced apoptosis. Apoptosis (2001) 1.22
Atm is dispensable for p53 apoptosis and tumor suppression triggered by cell cycle dysfunction. Mol Cell Biol (1999) 1.19
Increased levels of E2F-1-dependent DNA binding activity after UV- or gamma-irradiation. Nucleic Acids Res (1999) 1.18
p19(ARF) is dispensable for oncogenic stress-induced p53-mediated apoptosis and tumor suppression in vivo. Mol Cell Biol (2002) 1.12
Stress signals induce transcriptionally inactive E2F-1 independently of p53 and Rb. Oncogene (2000) 1.11
p53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin. Int J Oncol (1999) 1.07
Autophosphorylation of checkpoint kinase 2 at serine 516 is required for radiation-induced apoptosis. J Biol Chem (2003) 1.07
ARF differentially modulates apoptosis induced by E2F1 and Myc. Mol Cell Biol (2002) 1.07
Checkpoint kinase 2 (Chk2) monomers or dimers phosphorylate Cdc25C after DNA damage regardless of threonine 68 phosphorylation. J Biol Chem (2002) 1.04
Human papillomavirus type 16 E7 regulates E2F and contributes to mitogenic signalling. Oncogene (1993) 1.03
Role for E2F in DNA damage-induced entry of cells into S phase. Cancer Res (1997) 1.00
p53 mutant mice that display early ageing-associated phenotypes. Nature (2002) 10.05
PTC124 targets genetic disorders caused by nonsense mutations. Nature (2007) 6.67
Superior survival with capecitabine plus docetaxel combination therapy in anthracycline-pretreated patients with advanced breast cancer: phase III trial results. J Clin Oncol (2002) 4.47
Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study. Lancet (2008) 3.21
Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. J Med Chem (2005) 2.77
Pathogenic Leptospira species express surface-exposed proteins belonging to the bacterial immunoglobulin superfamily. Mol Microbiol (2003) 2.53
Deregulated Ras signaling compromises DNA damage checkpoint recovery in S. cerevisiae. Cell Cycle (2010) 2.05
Surfaceome of Leptospira spp. Infect Immun (2005) 1.90
Chk1 in the DNA damage response: conserved roles from yeasts to mammals. DNA Repair (Amst) (2004) 1.85
Regulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on Ser-345. J Biol Chem (2003) 1.82
von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination. Proc Natl Acad Sci U S A (2003) 1.78
Homozygous mutation in SAMHD1 gene causes cerebral vasculopathy and early onset stroke. Proc Natl Acad Sci U S A (2011) 1.62
Phase III multicenter trial of doxorubicin plus cyclophosphamide followed by paclitaxel compared with doxorubicin plus paclitaxel followed by weekly paclitaxel as adjuvant therapy for women with high-risk breast cancer. J Clin Oncol (2010) 1.56
Human cytomegalovirus immediate early proteins and cell growth control. Gene (2002) 1.54
Osmolarity, a key environmental signal controlling expression of leptospiral proteins LigA and LigB and the extracellular release of LigA. Infect Immun (2005) 1.52
Extensive genome-wide variability of human cytomegalovirus in congenitally infected infants. PLoS Pathog (2011) 1.45
Mammalian Polo-like kinase 3 (Plk3) is a multifunctional protein involved in stress response pathways. Oncogene (2002) 1.40
Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling. J Biol Chem (2001) 1.37
Inhibition of the ATM/p53 signal transduction pathway by Kaposi's sarcoma-associated herpesvirus interferon regulatory factor 1. J Virol (2006) 1.33
Viral Bcl-2-mediated evasion of autophagy aids chronic infection of gammaherpesvirus 68. PLoS Pathog (2009) 1.31
E2F1 induces phosphorylation of p53 that is coincident with p53 accumulation and apoptosis. Mol Cell Biol (2002) 1.30
The DNA damage checkpoint and PKA pathways converge on APC substrates and Cdc20 to regulate mitotic progression. Nat Cell Biol (2004) 1.28
Cesarean scar endometriosis. A report of two cases. J Reprod Med (2002) 1.20
Genetic analysis of cytomegalovirus in malignant gliomas. J Virol (2012) 1.19
Clinical outcomes after insulin initiation in patients with type 2 diabetes: 6-month data from the INSTIGATE observational study in five European countries. Curr Med Res Opin (2011) 1.12
Activated checkpoint kinase 2 provides a survival signal for tumor cells. Cancer Res (2006) 1.12
Prostate cancer stem cells: do they have a basal or luminal phenotype? Horm Cancer (2011) 1.12
Interferon-gamma release assay (modified QuantiFERON) as a potential marker of infection for Leishmania donovani, a proof of concept study. PLoS Negl Trop Dis (2011) 1.11
Osmotic regulation of expression of two extracellular matrix-binding proteins and a haemolysin of Leptospira interrogans: differential effects on LigA and Sph2 extracellular release. Microbiology (2007) 1.10
Rapid intrahost evolution of human cytomegalovirus is shaped by demography and positive selection. PLoS Genet (2013) 1.09
Cross-terminology mapping challenges: a demonstration using medication terminological systems. J Biomed Inform (2012) 1.06
An E2F1-mediated DNA damage response contributes to the replication of human cytomegalovirus. PLoS Pathog (2011) 1.04
Human cytomegalovirus IE1-72 activates ataxia telangiectasia mutated kinase and a p53/p21-mediated growth arrest response. J Virol (2005) 1.04
Petrous temporal bone cholesteatoma: a new classification and long-term surgical outcomes. Skull Base (2008) 1.04
Deregulation of DNA damage signal transduction by herpesvirus latency-associated M2. J Virol (2006) 1.04
Regulatory interactions between the checkpoint kinase Chk1 and the proteins of the DNA-dependent protein kinase complex. J Biol Chem (2003) 1.04
Gene silencing in the endocrine pancreas mediated by short-interfering RNA. Pancreas (2005) 1.02
Evolution of the influenza A virus genome during development of oseltamivir resistance in vitro. J Virol (2013) 1.01
A role for Saccharomyces cerevisiae Chk1p in the response to replication blocks. Mol Biol Cell (2004) 0.98
A single chromosome addition from Thinopyrum elongatum confers a polycarpic, perennial habit to annual wheat. J Exp Bot (2004) 0.97
Mutualism promotes diversity and stability in a simple artificial ecosystem. Artif Life (2002) 0.97
HCMV infection: modulating the cell cycle and cell death. Int Rev Immunol (2003) 0.96
Female sexual dysfunction after radical cystectomy: a new outcome measure. Urology (2004) 0.95
Treatment of advanced hormone-sensitive breast cancer in postmenopausal women with exemestane alone or in combination with celecoxib. J Clin Oncol (2008) 0.95
Docetaxel-containing adjuvant chemotherapy in patients with early stage breast cancer. Consistency of effect independent of nodal and biomarker status: a meta-analysis of 14 randomized clinical trials. Breast Cancer Res Treat (2012) 0.93
Life, death and E2F: linking proliferation control and DNA damage signaling via E2F1. Cell Cycle (2004) 0.93
ATRMec1 phosphorylation-independent activation of Chk1 in vivo. J Biol Chem (2008) 0.93
Long-term potency after early use of a vacuum erection device following radical prostatectomy. BJU Int (2010) 0.92
Stereotactic placement of depth electrodes in medically intractable epilepsy. J Neurosurg (2014) 0.92
The Rho1p exchange factor Rgf1p signals upstream from the Pmk1 mitogen-activated protein kinase pathway in fission yeast. Mol Biol Cell (2008) 0.91
U2OS cells lacking Chk1 undergo aberrant mitosis and fail to activate the spindle checkpoint. J Cell Mol Med (2009) 0.91
Xenografts in zebrafish embryos as a rapid functional assay for breast cancer stem-like cell identification. Cell Cycle (2011) 0.89
Was it something she ate? Case report and discussion of scombroid poisoning. CMAJ (2003) 0.89
Professional fighters brain health study: rationale and methods. Am J Epidemiol (2013) 0.89
Active RB elicits late G1/S inhibition. Exp Cell Res (2002) 0.89
The prevalence and onset of gaze modulation of tinnitus and increased sensitivity to noise after translabyrinthine vestibular schwannoma excision. Otol Neurotol (2006) 0.87
Regulation of the stem cell marker CD133 is independent of promoter hypermethylation in human epithelial differentiation and cancer. Mol Cancer (2011) 0.85
Radiation Sensitivity and Tumor Susceptibility in ATM Phospho-Mutant ATF2 Mice. Genes Cancer (2010) 0.85
Erythropoietin mimics the acute phase response in critical illness. Crit Care (2003) 0.85
The inhibitory effect of intravenous lidocaine infusion on tinnitus after translabyrinthine removal of vestibular schwannoma: a double-blind, placebo-controlled, crossover study. Otol Neurotol (2005) 0.84
Effectiveness and neural mechanisms associated with tDCS delivered to premotor cortex in stroke rehabilitation: study protocol for a randomized controlled trial. Trials (2013) 0.84
Vacuum erection devices revisited: its emerging role in the treatment of erectile dysfunction and early penile rehabilitation following prostate cancer therapy. J Sex Med (2010) 0.83
Neurovascular preservation in orthotopic cystectomy: impact on female sexual function. Urology (2006) 0.83
Orchestration of the S-phase and DNA damage checkpoint pathways by replication forks from early origins. J Cell Biol (2008) 0.83
Realization of quantitative-grade fieldable snapshot imaging spectropolarimeter. Opt Express (2004) 0.82
Differential cytotoxic activity of a novel palladium-based compound on prostate cell lines, primary prostate epithelial cells and prostate stem cells. PLoS One (2013) 0.82
Proteins in the nutrient-sensing and DNA damage checkpoint pathways cooperate to restrain mitotic progression following DNA damage. PLoS Genet (2011) 0.82
Reported toxicity in 1486 liquid detergent capsule exposures to the UK National Poisons Information Service 2009-2012, including their ophthalmic and CNS effects. Clin Toxicol (Phila) (2013) 0.81
Conserved ATRMec1 phosphorylation-independent activation of Chk1 by single amino acid substitution in the GD domain. Cell Cycle (2009) 0.81
An internal polyadenylation signal substantially increases expression levels of lentivirus-delivered transgenes but has the potential to reduce viral titer in a promoter-dependent manner. Hum Gene Ther (2008) 0.81
Epstein-Barr virus latent membrane protein 1 genetic variability in peripheral blood B cells and oropharyngeal fluids. J Virol (2014) 0.80
RNA interference-mediated targeting of human cytomegalovirus immediate-early or early gene products inhibits viral replication with differential effects on cellular functions. J Virol (2012) 0.80
The fission yeast cell wall stress sensor-like proteins Mtl2 and Wsc1 act by turning on the GTPase Rho1p but act independently of the cell wall integrity pathway. Microbiologyopen (2013) 0.78
Discovery of a small molecule targeting IRA2 deletion in budding yeast and neurofibromin loss in malignant peripheral nerve sheath tumor cells. Mol Cancer Ther (2011) 0.78
Stopped for repairs: a new role for nutrient sensing pathways? Cell Cycle (2004) 0.77
Capecitabine plus docetaxel combination therapy. Cancer (2005) 0.77
Effect of bauxite mineralized soil on residual metal levels in some post harvest food crops in Jamaica. Bull Environ Contam Toxicol (2012) 0.77
A novel DDB2-ATM feedback loop regulates human cytomegalovirus replication. J Virol (2013) 0.77
Polymorphic nuclear gene sequences indicate a novel genome donor in the polyploid genus Thinopyrum. Hereditas (2011) 0.76
A new technique using fibrin glue in the management of auricular hematoma. Clin J Sport Med (2014) 0.76
Preventing baker's asthma. Occup Med (Lond) (2004) 0.75
Evaluation of citrus fibers as a tablet excipient. AAPS PharmSciTech (2013) 0.75
Phase II Trial of a Novel Paclitaxel Schedule As Single-Agent, First-Line Therapy for HER-2/neu-Negative Metastatic Breast Cancer: A Community-Based Study. J Oncol Pract (2006) 0.75
Is distal screw entry point associated with subtrochanteric fracture after intracapsular hip fracture fixation? ANZ J Surg (2014) 0.75
Should decision models drive the decision for prostate biopsy? Urol Oncol (2011) 0.75
Dental Sedation Teachers Group Annual Symposium. Royal College of Surgeons, Glasgow, 26 April 2005. SAAD Dig (2006) 0.75
Analytical approaches for quantification of a Nrf2 pathway activator: overcoming bioanalytical challenges to support a toxicity study. Analyst (2014) 0.75
Impact of disease burden on cryoablation prostate-specific antigen outcomes. Urology (2009) 0.75
Molecular Basis for Differential Patterns of Drug Resistance in Influenza N1 and N2 Neuraminidase. J Chem Theory Comput (2016) 0.75
MELANOCYTOMA OR JUXTAPAPILLARY MELANOMA? Retin Cases Brief Rep (2017) 0.75
The "enhanced N35" somatosensory evoked potential: its associations and potential utility in the clinical evaluation of dystonia and myoclonus. J Neurol (2007) 0.75
Structure-activity relationships in aminosterol antibiotics: the effect of stereochemistry at the 7-OH group. Bioorg Med Chem Lett (2013) 0.75