Published in FASEB J on January 01, 1999
Choline availability during embryonic development alters progenitor cell mitosis in developing mouse hippocampus. J Nutr (2003) 1.73
Choline availability modulates human neuroblastoma cell proliferation and alters the methylation of the promoter region of the cyclin-dependent kinase inhibitor 3 gene. J Neurochem (2004) 1.40
Peroxisomal lipid synthesis regulates inflammation by sustaining neutrophil membrane phospholipid composition and viability. Cell Metab (2015) 1.29
Choline deficiency increases lymphocyte apoptosis and DNA damage in humans. Am J Clin Nutr (2006) 1.18
The xipotl mutant of Arabidopsis reveals a critical role for phospholipid metabolism in root system development and epidermal cell integrity. Plant Cell (2004) 1.14
Maternal dietary choline availability alters the balance of netrin-1 and DCC neuronal migration proteins in fetal mouse brain hippocampus. Brain Res Dev Brain Res (2005) 1.06
Regulation of choline deficiency apoptosis by epidermal growth factor in CWSV-1 rat hepatocytes. Cell Physiol Biochem (2005) 1.05
Multifunctional actions of approved and candidate stroke drugs. Neurotherapeutics (2009) 1.03
Homocysteine as a risk factor for atherosclerosis: is its conversion to s-adenosyl-L-homocysteine the key to deregulated lipid metabolism? J Lipids (2011) 0.92
Effects of hypoxia, glucose deprivation and acidosis on phosphatidylcholine synthesis in HL-1 cardiomyocytes. CTP:phosphocholine cytidylyltransferase activity correlates with sarcolemmal disruption. Biochem J (2006) 0.88
Dietary choline reverses some, but not all, effects of folate deficiency on neurogenesis and apoptosis in fetal mouse brain. J Nutr (2010) 0.87
Effect of tricyclodecan-9-yl potassium xanthate (D609) on phospholipid metabolism and cell death during oxygen-glucose deprivation in PC12 cells. Neuroscience (2007) 0.86
Asthma, allergy, and responses to methyl donor supplements and nutrients. J Allergy Clin Immunol (2013) 0.85
Proton magnetic resonance spectroscopy ((1)H-MRS) reveals geniculocalcarine and striate area degeneration in primary glaucoma. PLoS One (2013) 0.84
Induction of apoptosis by lipophilic activators of CTP:phosphocholine cytidylyltransferase alpha (CCTalpha). Biochem J (2005) 0.83
NMR spectroscopy of human eye tissues: a new insight into ocular biochemistry. ScientificWorldJournal (2014) 0.81
Increased levels of choline metabolites are an early marker of docetaxel treatment response in BRCA1-mutated mouse mammary tumors: an assessment by ex vivo proton magnetic resonance spectroscopy. J Transl Med (2015) 0.79
Interactions of ethanol and folate deficiency in development of alcoholic liver disease in the micropig. Trans Am Clin Climatol Assoc (2002) 0.79
Differential modification of the phospholipid profile by transient ischemia in rat hippocampal CA1 and CA3 regions. Prostaglandins Leukot Essent Fatty Acids (2013) 0.77
Targeting Phospholipid Metabolism in Cancer. Front Oncol (2016) 0.77
Pathology of bursae of Fabricius in methionine-deficient broiler chickens. Nutrients (2013) 0.76
Nutritional deficiencies and phospholipid metabolism. Int J Mol Sci (2011) 0.76
Preclinical study of treatment response in HCT-116 cells and xenografts with (1) H-decoupled (31) P MRS. NMR Biomed (2011) 0.76
The E2F2 transcription factor sustains hepatic glycerophospholipid homeostasis in mice. PLoS One (2014) 0.75
Randomized, double-blind, placebo-controlled clinical trial of choline supplementation in school-aged children with fetal alcohol spectrum disorders. Am J Clin Nutr (2016) 0.75
Current knowledge on the neuroprotective and neuroregenerative properties of citicoline in acute ischemic stroke. J Exp Pharmacol (2015) 0.75
Ceramide-1-phosphate protection of cochlear hair cells against cisplatin ototoxicity. Toxicol Rep (2016) 0.75
Choline availability alters embryonic development of the hippocampus and septum in the rat. Brain Res Dev Brain Res (1999) 1.90
Getting nutrition education into medical schools: a computer-based approach. Am J Clin Nutr (2000) 1.73
Maternal dietary choline availability alters mitosis, apoptosis and the localization of TOAD-64 protein in the developing fetal rat septum. Brain Res Dev Brain Res (1999) 1.65
Formation of methylamines from ingested choline and lecithin. J Pharmacol Exp Ther (1983) 1.51
Pregnancy and lactation are associated with diminished concentrations of choline and its metabolites in rat liver. J Nutr (1995) 1.49
Severe folate deficiency causes secondary depletion of choline and phosphocholine in rat liver. J Nutr (1994) 1.42
Dietary choline: biochemistry, physiology, and pharmacology. Annu Rev Nutr (1981) 1.33
Choline and choline esters in human and rat milk and in infant formulas. Am J Clin Nutr (1996) 1.27
Inhibitors of choline uptake and metabolism cause developmental abnormalities in neurulating mouse embryos. Teratology (2001) 1.21
Effects of choline deficiency and methotrexate treatment upon liver folate content and distribution. Cancer Res (1991) 1.20
Failure to thrive. Pediatr Clin North Am (1988) 1.18
Maternal choline availability alters the localization of p15Ink4B and p27Kip1 cyclin-dependent kinase inhibitors in the developing fetal rat brain hippocampus. Dev Neurosci (2001) 1.15
Diet and carcinogenesis. Carcinogenesis (1993) 1.15
Synthesis of lecithin (phosphatidylcholine) from phosphatidylethanolamine in bovine brain. Brain Res (1979) 1.14
Choline deficiency induces apoptosis in SV40-immortalized CWSV-1 rat hepatocytes in culture. FASEB J (1996) 1.11
Choline, phosphatidylcholine and sphingomyelin in human and bovine milk and infant formulas. J Nutr (1986) 1.08
Developmental changes in rat blood choline concentration. Biochem J (1981) 1.07
The measurement of dimethylamine, trimethylamine, and trimethylamine N-oxide using capillary gas chromatography-mass spectrometry. Anal Biochem (1990) 1.07
Effects of choline deficiency and methotrexate treatment upon rat liver. J Nutr Biochem (1990) 1.05
Elevated choline concentration in neonatal plasma. Life Sci (1980) 1.04
S-Adenosylhomocysteine hydrolase deficiency: a second patient, the younger brother of the index patient, and outcomes during therapy. J Inherit Metab Dis (2005) 1.03
S-adenosylhomocysteine hydrolase deficiency in a 26-year-old man. J Inherit Metab Dis (2006) 1.03
Exercise intensity-related responses of beta-endorphin and catecholamines. Med Sci Sports Exerc (1987) 1.03
Choline deficiency induces apoptosis in primary cultures of fetal neurons. FASEB J (2001) 1.02
Developmental changes in the activity of phosphatidylethanolamine N-methyltransferases in rat brain. Biochem J (1985) 1.00
Measurement of choline and choline metabolite concentrations using high-pressure liquid chromatography and gas chromatography-mass spectrometry. Anal Biochem (1989) 0.99
Choline availability modulates the expression of TGFbeta1 and cytoskeletal proteins in the hippocampus of developing rat brain. Neurochem Res (1998) 0.99
Lecithin and choline in human health and disease. Nutr Rev (1994) 0.98
Metabolomics in the opening decade of the 21st century: building the roads to individualized health. J Nutr (2004) 0.98
Uptake of choline by rat mammary-gland epithelial cells. Biochem J (1988) 0.97
Prolonged fasting in humans results in diminished plasma choline concentrations but does not cause liver dysfunction. Am J Clin Nutr (1997) 0.96
Opposing regulation of choline deficiency-induced apoptosis by p53 and nuclear factor kappaB. J Biol Chem (2001) 0.95
Effects of ingesting soy or egg lecithins on serum choline, brain choline and brain acetylcholine. J Nutr (1981) 0.94
Apoptosis is induced by choline deficiency in fetal brain and in PC12 cells. Brain Res Dev Brain Res (1997) 0.93
Diet and sleep patterns in newborn infants. N Engl J Med (1983) 0.93
Choline distribution and metabolism in pregnant rats and fetuses are influenced by the choline content of the maternal diet. J Nutr (1995) 0.92
Rat and human mammary tissue can synthesize choline moiety via the methylation of phosphatidylethanolamine. Biochem J (1988) 0.92
Normal plasma choline responses to ingested lecithin. Neurology (1980) 0.91
The effects of choline supplementation on physical performance. Int J Sport Nutr Exerc Metab (2000) 0.91
Choline deficiency selects for resistance to p53-independent apoptosis and causes tumorigenic transformation of rat hepatocytes. Carcinogenesis (1997) 0.91
Accumulation of 1,2-sn-diradylglycerol with increased membrane-associated protein kinase C may be the mechanism for spontaneous hepatocarcinogenesis in choline-deficient rats. J Biol Chem (1993) 0.90
Quantitative analysis of the principle soy isoflavones genistein, daidzein and glycitein, and their primary conjugated metabolites in human plasma and urine using reversed-phase high-performance liquid chromatography with ultraviolet detection. J Chromatogr B Biomed Sci Appl (2001) 0.90
Uptake of free choline by isolated perfused rat liver. Proc Natl Acad Sci U S A (1980) 0.89
Increase in human exposure to methylamine precursors of N-nitrosamines after eating fish. Cancer Res (1986) 0.89
Potential mechanisms of tumorigenic action of diethanolamine in mice. Toxicol Lett (2000) 0.89
Choline deficiency causes increased localization of transforming growth factor-beta1 signaling proteins and apoptosis in the rat liver. Pathobiology (1997) 0.89
Diet-hormone interrelationships in the rat. J Nutr (1978) 0.88
Formation of unesterified choline by rat brain. Biochim Biophys Acta (1985) 0.88
Effects of prolonged (1 year) choline deficiency and subsequent re-feeding of choline on 1,2-sn-diradylglycerol, fatty acids and protein kinase C in rat liver. Carcinogenesis (1995) 0.87
Plasma choline concentration in humans fed parenterally. Am J Clin Nutr (1986) 0.86
Methyl-group donors cannot prevent apoptotic death of rat hepatocytes induced by choline-deficiency. J Cell Biochem (1997) 0.86
One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels. J Inherit Metab Dis (1998) 0.86
Measurement of the formation of betaine aldehyde and betaine in rat liver mitochondria by a high pressure liquid chromatography-radioenzymatic assay. Biochim Biophys Acta (1992) 0.85
Hepatic protein kinase C is not activated despite high intracellular 1,2-sn-diacylglycerol in obese Zucker rats. Biochim Biophys Acta (1997) 0.85
Introducing cancer nutrition to medical students: effectiveness of computer-based instruction. Am J Clin Nutr (2000) 0.83
Effectiveness of orthotopic liver transplantation on the restoration of cholesterol metabolism in patients with end-stage liver disease. Gastroenterology (1987) 0.83
An in vitro study of choline uptake by intestine from neonatal and adult rats. Pediatr Res (1986) 0.82
Influence of caffeine on exercise performance in habitual caffeine users. Int J Sports Med (1986) 0.82
Estrogens reduce bone loss in the ovariectomized, lactating rat model. Bone Miner (1991) 0.82
Endogenous formation of dimethylamine. Biochem J (1985) 0.81
Procarbazine carcinogenicity in methotrexate-treated or lipotrope-deficient male rats. Carcinogenesis (1990) 0.81
Tyrosine for depression: a double-blind trial. J Affect Disord (1990) 0.81
Betaine in wine: answer to the French paradox? Med Hypotheses (1999) 0.81
Abnormal liver function in malnourished patients receiving total parenteral nutrition: a prospective randomized study. J Am Coll Nutr (1990) 0.80
Formation of trimethylamine from dietary choline by Streptococcus sanguis I, which colonizes the mouth. J Nutr Biochem (1990) 0.80
Dietary antioxidant depletion: enhancement of tumor apoptosis and inhibition of brain tumor growth in transgenic mice. Carcinogenesis (2000) 0.80
Evaluation of the potential of triethanolamine to alter hepatic choline levels in female B6C3F1 mice. Toxicol Sci (2004) 0.80
Glycerophosphocholine and phosphocholine are the major choline metabolites in rat milk. J Nutr (1993) 0.79
The ovariectomized, lactating rat as an experimental model for osteopenia: calcium metabolism and bone changes. Bone Miner (1990) 0.79
Decreased loss of liver adenosine triphosphate during hypothermic preservation in rats pretreated with glucose: implications for organ donor management. Gastroenterology (1988) 0.79
Diet, apoptosis, and carcinogenesis. Adv Exp Med Biol (1997) 0.78
Diets enriched with N-3 fatty acids ameliorate lactic acidosis by improving endotoxin-induced tissue hypoperfusion in guinea pigs. Ann Surg (1991) 0.77
Neuroendocrine responses of type A individuals to exercise. Behav Med (1989) 0.77
Choline: an essential dietary nutrient? Nutrition (1992) 0.77
Choline content of mothers' milk in Ecuador and Boston. N Engl J Med (1982) 0.77
Lipid synthesis and secretion by primary cultures of rat mammary epithelial cells. J Cell Physiol (1993) 0.77
1,2-sn-diacylglycerol accumulates in choline-deficient liver. A possible mechanism of hepatic carcinogenesis via alteration in protein kinase C activity? FEBS Lett (1989) 0.76
Short-term TPN containing n-3 fatty acids ameliorate lactic acidosis induced by endotoxin in guinea pigs. Am J Clin Nutr (1990) 0.76
Maternal methionine adenosyltransferase I/III deficiency: reproductive outcomes in a woman with four pregnancies. J Inherit Metab Dis (2003) 0.76
Amniotic-fluid total cholinesterase and neural-tube defects. Lancet (1979) 0.75
Radioactive choline metabolism in guinea pig gallbladder. Is there measurable acetylcholine release? Dig Dis Sci (1995) 0.75
Prenatal diagnosis of neural tube defects. V. The value of amniotic fluid cholinesterase studies. Am J Obstet Gynecol (1980) 0.75
Use of choline and lecithin in the treatment of tardive dyskinesia. Adv Biochem Psychopharmacol (1980) 0.75
Nutrients, neurotransmitters and infant behavior. Am J Clin Nutr (1985) 0.75
Developmental changes in brain indoles, serum tryptophan and other serum neutral amino acids in the rat. Brain Res (1981) 0.75