Published in Brain Res Dev Brain Res on October 06, 2005
Diethanolamine alters neurogenesis and induces apoptosis in fetal mouse hippocampus. FASEB J (2006) 1.47
Phosphatidylethanolamine N-methyltransferase (PEMT) gene expression is induced by estrogen in human and mouse primary hepatocytes. FASEB J (2007) 1.42
Prenatal choline supplementation mitigates the adverse effects of prenatal alcohol exposure on development in rats. Neurotoxicol Teratol (2009) 1.30
Choline deficiency alters global histone methylation and epigenetic marking at the Re1 site of the calbindin 1 gene. FASEB J (2009) 1.21
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Maternal dietary choline deficiency alters angiogenesis in fetal mouse hippocampus. Proc Natl Acad Sci U S A (2010) 1.09
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The supply of choline is important for fetal progenitor cells. Semin Cell Dev Biol (2011) 0.87
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The versatile roles of "axon guidance" cues in tissue morphogenesis. Dev Cell (2004) 1.55
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Maternal choline availability alters the localization of p15Ink4B and p27Kip1 cyclin-dependent kinase inhibitors in the developing fetal rat brain hippocampus. Dev Neurosci (2001) 1.15
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Choline availability during embryonic development alters the localization of calretinin in developing and aging mouse hippocampus. Nutr Neurosci (2003) 1.10
Regulation of choline deficiency apoptosis by epidermal growth factor in CWSV-1 rat hepatocytes. Cell Physiol Biochem (2005) 1.05
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Localization of immunoreactivity for deleted in colorectal cancer (DCC), the receptor for the guidance factor netrin-1, in ventral tier dopamine projection pathways in adult rodents. Neuroscience (2005) 0.94
Apoptosis is induced by choline deficiency in fetal brain and in PC12 cells. Brain Res Dev Brain Res (1997) 0.93
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Concentrations of choline-containing compounds and betaine in common foods. J Nutr (2003) 4.12
Quantitation of choline and its metabolites in tissues and foods by liquid chromatography/electrospray ionization-isotope dilution mass spectrometry. Anal Chem (2002) 2.35
Polymorphism of the PEMT gene and susceptibility to nonalcoholic fatty liver disease (NAFLD). FASEB J (2005) 2.34
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Association between composition of the human gastrointestinal microbiome and development of fatty liver with choline deficiency. Gastroenterology (2010) 2.30
Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains. FASEB J (2006) 2.07
Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst (2007) 2.07
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women. Am J Clin Nutr (2013) 1.88
Common genetic polymorphisms affect the human requirement for the nutrient choline. FASEB J (2006) 1.88
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Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans. Proc Natl Acad Sci U S A (2005) 1.73
Choline availability during embryonic development alters progenitor cell mitosis in developing mouse hippocampus. J Nutr (2003) 1.73
Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study. Am J Clin Nutr (2006) 1.71
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Choline deficiency in mice and humans is associated with increased plasma homocysteine concentration after a methionine load. Am J Clin Nutr (2005) 1.66
Clinical characteristics and pharmacokinetics of purified soy isoflavones: single-dose administration to healthy men. Am J Clin Nutr (2002) 1.60
Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency. FASEB J (2003) 1.59
Diethanolamine induces hepatic choline deficiency in mice. Toxicol Sci (2002) 1.57
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Choline metabolism and risk of breast cancer in a population-based study. FASEB J (2008) 1.51
Diethanolamine alters neurogenesis and induces apoptosis in fetal mouse hippocampus. FASEB J (2006) 1.47
Usual choline and betaine dietary intake and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study. BMC Cardiovasc Disord (2007) 1.47
Elevated serum creatine phosphokinase in choline-deficient humans: mechanistic studies in C2C12 mouse myoblasts. Am J Clin Nutr (2004) 1.46
Nutrition education in U.S. medical schools: latest update of a national survey. Acad Med (2010) 1.42
Phosphatidylethanolamine N-methyltransferase (PEMT) gene expression is induced by estrogen in human and mouse primary hepatocytes. FASEB J (2007) 1.42
Perturbations in choline metabolism cause neural tube defects in mouse embryos in vitro. FASEB J (2002) 1.41
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Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas. J Biol Chem (2011) 1.40
Choline availability modulates human neuroblastoma cell proliferation and alters the methylation of the promoter region of the cyclin-dependent kinase inhibitor 3 gene. J Neurochem (2004) 1.40
Phosphatidylethanolamine-N-methyltransferase activity and dietary choline regulate liver-plasma lipid flux and essential fatty acid metabolism in mice. J Nutr (2003) 1.36
Folic acid deficiency during late gestation decreases progenitor cell proliferation and increases apoptosis in fetal mouse brain. J Nutr (2004) 1.35
Second trimester folate status and preterm birth. Am J Obstet Gynecol (2004) 1.32
Choline deficiency alters global histone methylation and epigenetic marking at the Re1 site of the calbindin 1 gene. FASEB J (2009) 1.21
Safety and pharmacokinetics of purified soy isoflavones: single-dose administration to postmenopausal women. Am J Clin Nutr (2002) 1.19
Metabolomic profiling can predict which humans will develop liver dysfunction when deprived of dietary choline. FASEB J (2010) 1.18
Choline deficiency increases lymphocyte apoptosis and DNA damage in humans. Am J Clin Nutr (2006) 1.18
Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. Curr Opin Gastroenterol (2012) 1.17
BRCA1 promoter methylation is associated with increased mortality among women with breast cancer. Breast Cancer Res Treat (2008) 1.16
The association between betaine and choline intakes and the plasma concentrations of homocysteine in women. Am J Clin Nutr (2007) 1.16
Repeatability and measurement error in the assessment of choline and betaine dietary intake: the Atherosclerosis Risk in Communities (ARIC) study. Nutr J (2009) 1.16
Nutrition in medicine: nutrition education for medical students and residents. Nutr Clin Pract (2010) 1.14
Choline availability during embryonic development alters the localization of calretinin in developing and aging mouse hippocampus. Nutr Neurosci (2003) 1.10
Ad libitum choline intake in healthy individuals meets or exceeds the proposed adequate intake level. J Nutr (2005) 1.10
Maternal dietary choline deficiency alters angiogenesis in fetal mouse hippocampus. Proc Natl Acad Sci U S A (2010) 1.09
The role of dietary supplements during cancer therapy. J Nutr (2003) 1.09
Clinical characteristics and pharmacokinetics of purified soy isoflavones: multiple-dose administration to men with prostate neoplasia. Nutr Cancer (2004) 1.06
Regulation of choline deficiency apoptosis by epidermal growth factor in CWSV-1 rat hepatocytes. Cell Physiol Biochem (2005) 1.05
Dietary isoflavones differentially induce gene expression changes in lymphocytes from postmenopausal women who form equol as compared with those who do not. J Nutr Biochem (2006) 1.04
Gene expression profiling of choline-deprived neural precursor cells isolated from mouse brain. Brain Res Mol Brain Res (2004) 1.04
Aberrant estrogen regulation of PEMT results in choline deficiency-associated liver dysfunction. J Biol Chem (2010) 1.04
GSTM1, GSTT1, GSTP1, and GSTA1 polymorphisms and urinary isothiocyanate metabolites following broccoli consumption in humans. J Nutr (2007) 1.03
Adverse event associated with methionine loading test: a case report. Arterioscler Thromb Vasc Biol (2002) 1.01
Alteration of bile acid metabolism in the rat induced by chronic ethanol consumption. FASEB J (2013) 1.00
Deletion of murine choline dehydrogenase results in diminished sperm motility. FASEB J (2010) 0.99
Choline intake and genetic polymorphisms influence choline metabolite concentrations in human breast milk and plasma. Am J Clin Nutr (2010) 0.99
Mitochondrial and microsomal derived reactive oxygen species mediate apoptosis induced by transforming growth factor-beta1 in immortalized rat hepatocytes. J Cell Biochem (2003) 0.99
High intakes of choline and betaine reduce breast cancer mortality in a population-based study. FASEB J (2009) 0.99
Computer-assisted teaching of nutritional anemias and diabetes to first-year medical students. Am J Clin Nutr (2002) 0.98
Lack of significant genotoxicity of purified soy isoflavones (genistein, daidzein, and glycitein) in 20 patients with prostate cancer. Am J Clin Nutr (2003) 0.98
Perinatal manipulation of α-linolenic acid intake induces epigenetic changes in maternal and offspring livers. FASEB J (2012) 0.98
Homocysteine metabolism in ZDF (type 2) diabetic rats. Diabetes (2005) 0.96
Understanding the role of nutrition in the brain and behavioral development of toddlers and preschool children: identifying and addressing methodological barriers. Nutr Neurosci (2009) 0.95
The evolution of Nutrition in Medicine, a computer-assisted nutrition curriculum. Am J Clin Nutr (2006) 0.95
Deficiency in methionine, tryptophan, isoleucine, or choline induces apoptosis in cultured cells. J Nutr (2002) 0.95
Deletion of the Pemt gene increases progenitor cell mitosis, DNA and protein methylation and decreases calretinin expression in embryonic day 17 mouse hippocampus. Brain Res Dev Brain Res (2004) 0.94
Adiponectin lowers glucose production by increasing SOGA. Am J Pathol (2010) 0.94
Dietary choline requirements of women: effects of estrogen and genetic variation. Am J Clin Nutr (2010) 0.92
Mouse betaine-homocysteine S-methyltransferase deficiency reduces body fat via increasing energy expenditure and impairing lipid synthesis and enhancing glucose oxidation in white adipose tissue. J Biol Chem (2012) 0.92
Inadequate intake of nutrients essential for neurodevelopment in children with fetal alcohol spectrum disorders (FASD). Neurotoxicol Teratol (2013) 0.92