Women's Health Study (WHS): A Randomized Trial of Low-dose Aspirin and Vitamin E in the Primary Prevention of Cardiovascular Disease and Cancer (WHS)

Clinical Trial ID NCT00000479

PubWeight™ 275.13‹?›

🔗 Visit the ClinicalTrials.gov page for NCT00000479

Top papers

Rank Title Journal Year PubWeight™‹?›
1 C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 2000 18.04
2 A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women. N Engl J Med 2005 17.32
3 Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med 2002 16.23
4 C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA 2001 15.85
5 Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study: a randomized controlled trial. JAMA 2005 12.09
6 Low-dose aspirin in the primary prevention of cancer: the Women's Health Study: a randomized controlled trial. JAMA 2005 9.03
7 C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: an 8-year follow-up of 14 719 initially healthy American women. Circulation 2003 6.99
8 C-reactive protein and the risk of developing hypertension. JAMA 2003 5.75
9 Non-HDL cholesterol, apolipoproteins A-I and B100, standard lipid measures, lipid ratios, and CRP as risk factors for cardiovascular disease in women. JAMA 2005 5.74
10 Baseline characteristics of participants in the Women's Health Study. J Womens Health Gend Based Med 2000 4.84
11 Prevalence of dry eye syndrome among US women. Am J Ophthalmol 2003 4.46
12 Fruit and vegetable intake and risk of cardiovascular disease: the Women's Health Study. Am J Clin Nutr 2000 3.99
13 Lipoprotein particle profiles by nuclear magnetic resonance compared with standard lipids and apolipoproteins in predicting incident cardiovascular disease in women. Circulation 2009 3.93
14 Physical activity and coronary heart disease in women: is "no pain, no gain" passé? JAMA 2001 3.65
15 Relationship of physical activity vs body mass index with type 2 diabetes in women. JAMA 2004 3.31
16 Relation between a diet with a high glycemic load and plasma concentrations of high-sensitivity C-reactive protein in middle-aged women. Am J Clin Nutr 2002 3.00
17 The long- and short-term impact of elevated body mass index on the risk of new atrial fibrillation the WHS (women's health study). J Am Coll Cardiol 2010 2.96
18 Interrelationships among circulating interleukin-6, C-reactive protein, and traditional cardiovascular risk factors in women. Arterioscler Thromb Vasc Biol 2002 2.79
19 C-reactive protein levels are not associated with increased risk for colorectal cancer in women. Ann Intern Med 2005 2.79
20 Prospective study of body mass index and risk of stroke in apparently healthy women. Circulation 2005 2.73
21 A prospective study of red meat consumption and type 2 diabetes in middle-aged and elderly women: the women's health study. Diabetes Care 2004 2.57
22 Migraine, vascular risk, and cardiovascular events in women: prospective cohort study. BMJ 2008 2.48
23 Hormone replacement therapy and dry eye syndrome. JAMA 2001 2.46
24 Migraine and coronary heart disease in women and men. Headache 2002 2.44
25 Low-density lipoprotein particle concentration and size as determined by nuclear magnetic resonance spectroscopy as predictors of cardiovascular disease in women. Circulation 2002 2.36
26 Alternate-day, low-dose aspirin and cancer risk: long-term observational follow-up of a randomized trial. Ann Intern Med 2013 2.33
27 Comparison of LDL cholesterol concentrations by Friedewald calculation and direct measurement in relation to cardiovascular events in 27,331 women. Clin Chem 2009 2.31
28 Birth weight is a significant risk factor for incident atrial fibrillation. Circulation 2010 2.30
29 Influence of systolic and diastolic blood pressure on the risk of incident atrial fibrillation in women. Circulation 2009 2.26
30 Dietary omega-3 fatty acids and fish consumption and risk of type 2 diabetes. Am J Clin Nutr 2010 2.25
31 Clinical usefulness of very high and very low levels of C-reactive protein across the full range of Framingham Risk Scores. Circulation 2004 2.16
32 A prospective study of dietary fiber intake and risk of cardiovascular disease among women. J Am Coll Cardiol 2002 2.10
33 C-reactive protein levels among women of various ethnic groups living in the United States (from the Women's Health Study). Am J Cardiol 2004 2.08
34 Low-dose aspirin for migraine prophylaxis in women. Cephalalgia 2001 2.07
35 Homocysteine, 5,10-methylenetetrahydrofolate reductase 677C>T polymorphism, nutrient intake, and incident cardiovascular disease in 24,968 initially healthy women. Clin Chem 2007 2.05
36 HbA1c measured in stored erythrocytes and mortality rate among middle-aged and older women. Diabetologia 2007 2.03
37 Lipoprotein(a) and risk of type 2 diabetes. Clin Chem 2010 2.01
38 Migraine, headache, and the risk of stroke in women: a prospective study. Neurology 2005 2.01
39 Relationship of total and abdominal adiposity with CRP and IL-6 in women. Ann Epidemiol 2003 1.98
40 Development of predictive models for long-term cardiovascular risk associated with systolic and diastolic blood pressure. Hypertension 2002 1.86
41 Maternal and paternal history of myocardial infarction and risk of cardiovascular disease in men and women. Circulation 2001 1.86
42 Dietary magnesium intake in relation to plasma insulin levels and risk of type 2 diabetes in women. Diabetes Care 2004 1.86
43 Interobserver agreement in the classification of stroke in the Women's Health Study. Stroke 2003 1.81
44 Plasma sex steroid hormones and risk of developing type 2 diabetes in women: a prospective study. Diabetologia 2007 1.80
45 Flavonoid intake and the risk of cardiovascular disease in women. Am J Clin Nutr 2003 1.79
46 Hemoglobin A1c level and future cardiovascular events among women. Arch Intern Med 2004 1.76
47 Relation between markers of systemic vascular inflammation and smoking in women. Am J Cardiol 2002 1.73
48 Sex hormone levels and risk of cardiovascular events in postmenopausal women. Circulation 2003 1.71
49 Soluble P-selectin and the risk of future cardiovascular events. Circulation 2001 1.69
50 Lipoprotein(a), hormone replacement therapy, and risk of future cardiovascular events. J Am Coll Cardiol 2008 1.69
51 Smoking and risk of hemorrhagic stroke in women. Stroke 2003 1.63
52 A prospective study of fruit and vegetable intake and the risk of type 2 diabetes in women. Diabetes Care 2004 1.63
53 Insulin, proinsulin, proinsulin:insulin ratio, and the risk of developing type 2 diabetes mellitus in women. Am J Med 2003 1.62
54 Associations of dietary flavonoids with risk of type 2 diabetes, and markers of insulin resistance and systemic inflammation in women: a prospective study and cross-sectional analysis. J Am Coll Nutr 2005 1.57
55 Blood pressure, C-reactive protein, and risk of future cardiovascular events. Circulation 2003 1.56
56 Is C-reactive protein specific for vascular disease in women? Ann Intern Med 2002 1.54
57 Soluble CD40L and cardiovascular risk in women. Circulation 2001 1.52
58 Lipoprotein particle size and concentration by nuclear magnetic resonance and incident type 2 diabetes in women. Diabetes 2010 1.52
59 Concentration in plasma of macrophage inhibitory cytokine-1 and risk of cardiovascular events in women: a nested case-control study. Lancet 2002 1.46
60 Individualised prediction of alternate-day aspirin treatment effects on the combined risk of cancer, cardiovascular disease and gastrointestinal bleeding in healthy women. Heart 2014 1.45
61 Randomised aspirin assignment and risk of adult-onset asthma in the Women's Health Study. Thorax 2008 1.45
62 C-reactive protein is independently associated with fasting insulin in nondiabetic women. Arterioscler Thromb Vasc Biol 2003 1.43
63 Measuring selection in contemporary human populations. Nat Rev Genet 2010 1.43
64 Magnesium intake, C-reactive protein, and the prevalence of metabolic syndrome in middle-aged and older U.S. women. Diabetes Care 2005 1.42
65 Risk of cardiovascular events among women with high normal blood pressure or blood pressure progression: prospective cohort study. BMJ 2007 1.40
66 The relative strength of C-reactive protein and lipid levels as determinants of ischemic stroke compared with coronary heart disease in women. J Am Coll Cardiol 2006 1.36
67 Plasma lycopene, other carotenoids, and retinol and the risk of cardiovascular disease in women. Am J Clin Nutr 2004 1.30
68 Dietary lycopene, tomato-based food products and cardiovascular disease in women. J Nutr 2003 1.30
69 Dietary fat and fatty acids and risk of colorectal cancer in women. Am J Epidemiol 2004 1.28
70 Lipid levels and the risk of ischemic stroke in women. Neurology 2007 1.23
71 Dietary glycemic load and risk of colorectal cancer in the Women's Health Study. J Natl Cancer Inst 2004 1.19
72 Dietary intakes of fruit, vegetables, and fiber, and risk of colorectal cancer in a prospective cohort of women (United States). Cancer Causes Control 2005 1.18
73 Job strain, job insecurity, and incident cardiovascular disease in the Women's Health Study: results from a 10-year prospective study. PLoS One 2012 1.17
74 Low-dose aspirin and breast cancer risk: results by tumour characteristics from a randomised trial. Br J Cancer 2008 1.14
75 Effect of low-dose aspirin on the occurrence of venous thromboembolism: a randomized trial. Ann Intern Med 2007 1.14
76 A novel protein glycan biomarker and future cardiovascular disease events. J Am Heart Assoc 2014 1.13
77 A randomized trial of low-dose aspirin in the prevention of clinical type 2 diabetes in women. Diabetes Care 2008 1.13
78 Past physical activity, current physical activity, and risk of coronary heart disease. Med Sci Sports Exerc 2005 1.13
79 Discordance of low-density lipoprotein (LDL) cholesterol with alternative LDL-related measures and future coronary events. Circulation 2013 1.10
80 Physical activity and breast cancer risk: the Women's Health Study (United States). Cancer Causes Control 2001 1.08
81 A prospective study of plasma lipid levels and hypertension in women. Arch Intern Med 2005 1.08
82 Additive value of immunoassay-measured fibrinogen and high-sensitivity C-reactive protein levels for predicting incident cardiovascular events. Circulation 2006 1.07
83 Coffee and caffeine consumption in relation to sex hormone-binding globulin and risk of type 2 diabetes in postmenopausal women. Diabetes 2010 1.01
84 Aspirin for primary prevention of vascular events in women: individualized prediction of treatment effects. Eur Heart J 2011 1.00
85 A prospective study of sugar intake and risk of type 2 diabetes in women. Diabetes Care 2003 1.00
86 Novel protein glycan side-chain biomarker and risk of incident type 2 diabetes mellitus. Arterioscler Thromb Vasc Biol 2015 0.97
87 Demographic predictors of eye care utilization among women. Med Care 2000 0.97
88 Age-related cataract in a randomized trial of beta-carotene in women. Ophthalmic Epidemiol 2004 0.96
89 Estrogen-progestin replacement therapy and breast cancer risk: the Women's Health Study (United States). Cancer Causes Control 2002 0.96
90 Active and passive smoking and risk of colds in women. Ann Epidemiol 2001 0.95
91 High-density lipoprotein particle subclass heterogeneity and incident coronary heart disease. Circ Cardiovasc Qual Outcomes 2013 0.95
92 Fruit and vegetable intake and the risk of cataract in women. Am J Clin Nutr 2005 0.93
93 Caffeine consumption and incident atrial fibrillation in women. Am J Clin Nutr 2010 0.92
94 Sex hormone-binding globulin and serum testosterone are inversely associated with C-reactive protein levels in postmenopausal women at high risk for cardiovascular disease. Ann Epidemiol 2005 0.92
95 Vitamin E in the primary prevention of rheumatoid arthritis: the Women's Health Study. Arthritis Rheum 2008 0.91
96 Dietary and plasma lycopene and the risk of breast cancer. Cancer Epidemiol Biomarkers Prev 2005 0.90
97 Dietary glycemic load and breast cancer risk in the Women's Health Study. Cancer Epidemiol Biomarkers Prev 2004 0.88
98 Circulating Vitamin D Levels and Risk of Colorectal Cancer in Women. Cancer Prev Res (Phila) 2015 0.88
99 Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. Am J Clin Nutr 2014 0.88
100 Interleukin-18 and the risk of future cardiovascular disease among initially healthy women. Atherosclerosis 2008 0.87
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