Published in Biochem Biophys Res Commun on May 10, 1999
Formation of native prions from minimal components in vitro. Proc Natl Acad Sci U S A (2007) 5.94
Selective incorporation of polyanionic molecules into hamster prions. J Biol Chem (2007) 1.71
Efficient in vitro amplification of chronic wasting disease PrPRES. J Virol (2007) 1.42
Prion hypothesis: the end of the controversy? Trends Biochem Sci (2010) 1.40
Perturbation of endoplasmic reticulum homeostasis facilitates prion replication. J Biol Chem (2007) 1.13
The intriguing prion disorders. Cell Mol Life Sci (2006) 1.09
Cellular factors implicated in prion replication. FEBS Lett (2010) 1.07
Proteasomal dysfunction and endoplasmic reticulum stress enhance trafficking of prion protein aggregates through the secretory pathway and increase accumulation of pathologic prion protein. J Biol Chem (2011) 0.94
In vitro amplification of misfolded prion protein using lysate of cultured cells. PLoS One (2011) 0.91
Enhanced virulence of sheep-passaged bovine spongiform encephalopathy agent is revealed by decreased polymorphism barriers in prion protein conversion studies. J Virol (2013) 0.82
Prion propagation in vitro: are we there yet? Int J Med Sci (2008) 0.82
Prion propagation and toxicity occur in vitro with two-phase kinetics specific to strain and neuronal type. J Virol (2012) 0.80
Glycoform-independent prion conversion by highly efficient, cell-based, protein misfolding cyclic amplification. Sci Rep (2016) 0.78
Phosphatidylethanolamine as a prion cofactor: potential implications for disease pathogenesis. Prion (2012) 0.76
In vitro amplification of scrapie and chronic wasting disease PrP(res) using baculovirus-expressed recombinant PrP as substrate. Prion (2014) 0.75
Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. Nature (2001) 6.20
Production of the Alzheimer amyloid beta protein by normal proteolytic processing. Science (1992) 5.22
Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. J Clin Invest (2000) 5.07
Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type. Science (1990) 4.71
Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid. Neurosci Lett (1992) 4.29
Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy. Nat Med (1998) 4.17
The amino acid sequence of a major nonimmunoglobulin component of some amyloid fibrils. J Clin Invest (1972) 3.96
An Actinophage for Streptomyces griseus. J Bacteriol (1947) 3.95
Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer. J Clin Oncol (1998) 3.79
Mutations in familial Creutzfeldt-Jakob disease and Gerstmann-Sträussler-Scheinker's syndrome. Exp Neurol (1989) 3.00
Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers. Proc Natl Acad Sci U S A (1996) 2.79
Down patients: extracellular preamyloid deposits precede neuritic degeneration and senile plaques. Neurosci Lett (1989) 2.69
Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro. Am J Pathol (1994) 2.66
The cerebrospinal-fluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex. Biochem J (1993) 2.66
Structural studies of immunoglobulin G. Nature (1969) 2.63
Defective gamma interferon production in leprosy. Reversal with antigen and interleukin 2. J Exp Med (1983) 2.61
Alzheimer neurofibrillary tangles: monoclonal antibodies to inherent antigen(s). Acta Neuropathol (1984) 2.58
The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein. Mol Cell Biol (1996) 2.57
Variations in the S-S bridges of immunoglobins G: interchain disulfide bridges of gamma G3 myeloma proteins. J Mol Biol (1968) 2.57
Localization of the X inactivation centre on the human X chromosome in Xq13. Nature (1991) 2.48
Copper stimulates endocytosis of the prion protein. J Biol Chem (1998) 2.47
Glycolipid-anchored proteins in neuroblastoma cells form detergent-resistant complexes without caveolin. J Cell Biol (1995) 2.46
A stop-codon mutation in the BRI gene associated with familial British dementia. Nature (1999) 2.46
Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis. Nat Med (2000) 2.44
Human amyloidosis, Alzheimer disease and related disorders. Lab Invest (1988) 2.44
An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease. Nature (1997) 2.42
Neurological illness in transgenic mice expressing a prion protein with an insertional mutation. Neuron (1998) 2.40
Infection-specific particle from the unconventional slow virus diseases. Science (1984) 2.34
The disulphide bonds of the heavy chain of rabbit immunoglobulin G. Biochem J (1970) 2.32
Alpha chain disease. Ann N Y Acad Sci (1971) 2.31
Preamyloid deposits in the cerebral cortex of patients with Alzheimer's disease and nondemented individuals. Neurosci Lett (1988) 2.26
Insulin resistance syndrome in a representative sample of children and adolescents from Quebec, Canada. Int J Obes Relat Metab Disord (2004) 2.26
Differences between vascular and plaque core amyloid in Alzheimer's disease. J Neurochem (1988) 2.24
Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein. J Virol (2000) 2.18
Bioaccumulation and toxicity of gold nanoparticles after repeated administration in mice. Biochem Biophys Res Commun (2010) 2.18
In vitro formation of amyloid fibrils from two synthetic peptides of different lengths homologous to Alzheimer's disease beta-protein. Biochem Biophys Res Commun (1986) 2.16
Systematic review and meta-analysis of intraoperative peritoneal lavage for colorectal cancer staging. Br J Surg (2013) 2.12
A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred. Proc Natl Acad Sci U S A (2000) 2.11
Cellular isoform of the scrapie agent protein participates in lymphocyte activation. Cell (1990) 2.06
Isolation and partial characterization of SAA-an amyloid-related protein from human serum. J Immunol (1976) 2.05
Apolipoprotein J (clusterin) and Alzheimer's disease. Microsc Res Tech (2000) 2.00
Nearly ubiquitous tissue distribution of the scrapie agent precursor protein. Neurology (1992) 2.00
The interactions of coupling ATPases with nucleotides. Biochim Biophys Acta (1978) 1.99
Fate of cerebrospinal fluid-borne amyloid beta-peptide: rapid clearance into blood and appreciable accumulation by cerebral arteries. J Neurochem (1996) 1.96
Boundary lubrication by lubricin is mediated by O-linked beta(1-3)Gal-GalNAc oligosaccharides. Glycoconj J (2001) 1.95
Immunological comparison of scrapie-associated fibrils isolated from animals infected with four different scrapie strains. J Virol (1986) 1.95
Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP. Proc Natl Acad Sci U S A (1996) 1.94
Reappraisal of hepatic arterial infusion in the treatment of nonresectable liver metastases from colorectal cancer. J Natl Cancer Inst (1996) 1.93
NEOMYCIN-PRODUCTION AND ANTIBIOTIC PROPERTIES. J Clin Invest (1949) 1.90
Molecular location of a species-specific epitope on the hamster scrapie agent protein. J Virol (1991) 1.89
Preferential association of kappa IIIb light chains with monoclonal human IgM kappa autoantibodies. J Immunol (1983) 1.87
A 25-kDa NH2-terminal fragment carries all the antibacterial activities of the human neutrophil 60-kDa bactericidal/permeability-increasing protein. J Biol Chem (1987) 1.86
Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme. Neuron (1996) 1.84
Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides. Biochem J (2000) 1.84
Primary structure of the "hinge" region of human IgG3. Probable quadruplication of a 15-amino acid residue basic unit. J Biol Chem (1977) 1.83
Apolipoprotein E: binding to soluble Alzheimer's beta-amyloid. Biochem Biophys Res Commun (1993) 1.80
Amyloid fibrils in hereditary cerebral hemorrhage with amyloidosis of Icelandic type is a variant of gamma-trace basic protein (cystatin C). Proc Natl Acad Sci U S A (1986) 1.78
Biochemical differences among scrapie-associated fibrils support the biological diversity of scrapie agents. J Gen Virol (1985) 1.75
A glycolipid-anchored prion protein is endocytosed via clathrin-coated pits. J Cell Biol (1994) 1.74
Amyloid protein of Gerstmann-Sträussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58. EMBO J (1991) 1.74
Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation. Biochem Biophys Res Commun (1996) 1.73
Nucleotide sequence of the small double-stranded RNA segment of bacteriophage phi 6: novel mechanism of natural translational control. J Virol (1986) 1.72
Fibrillogenesis in Alzheimer's disease of amyloid beta peptides and apolipoprotein E. Biochem J (1995) 1.72
Substitutions at codon 22 of Alzheimer's abeta peptide induce diverse conformational changes and apoptotic effects in human cerebral endothelial cells. J Biol Chem (2000) 1.71
Isolation and characterization of amyloid P component from Alzheimer's disease and other types of cerebral amyloidosis. Lab Invest (1988) 1.70
Amyloid fibrils in Gerstmann-Sträussler-Scheinker disease (Indiana and Swedish kindreds) express only PrP peptides encoded by the mutant allele. Cell (1994) 1.69
Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice. Am J Pathol (2001) 1.69
Detection of scrapie-associated fibril (SAF) proteins using anti-SAF antibody in non-purified tissue preparations. J Gen Virol (1986) 1.67
Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie. J Clin Invest (2001) 1.66
Insertion of influenza M protein into the viral lipid bilayer and localization of site of insertion. J Virol (1981) 1.65
Partial deletion in the heavy chain disease protein ZUC. Nature (1969) 1.65
Chromosome 14-encoded Alzheimer's disease: genetic and clinicopathological description. Ann Neurol (1994) 1.64
Prion protein amyloidosis. Brain Pathol (1996) 1.64
A prion protein cycles between the cell surface and an endocytic compartment in cultured neuroblastoma cells. J Biol Chem (1993) 1.64
Structural studies of human gamma-G-myeloma proteins of different antigenic subgroups and genetic specificities. J Exp Med (1966) 1.62
Apolipoprotein J and Alzheimer's amyloid beta solubility. Biochem J (1996) 1.61
Brain uptake of circulating apolipoproteins J and E complexed to Alzheimer's amyloid beta. Biochem Biophys Res Commun (1994) 1.60
Nomenclature of amyloid fibril proteins. Report from the meeting of the International Nomenclature Committee on Amyloidosis, August 8-9, 1998. Part 1. Amyloid (1999) 1.59
Hereditary cerebral hemorrhage with amyloidosis in patients of Dutch origin is related to Alzheimer disease. Proc Natl Acad Sci U S A (1987) 1.56
Antiidiotypic activity in the IgM fractions of mixed cryoglobulins. J Immunol (1980) 1.55
Amyloid fibril in hereditary cerebral hemorrhage with amyloidosis (HCHWA) is related to the gastroentero-pancreatic neuroendocrine protein, gamma trace. J Exp Med (1983) 1.55
Beta-2 microglobulin is an amyloidogenic protein in man. J Clin Invest (1985) 1.54
Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3. J Clin Invest (1994) 1.54
Reversion of prion protein conformational changes by synthetic beta-sheet breaker peptides. Lancet (2000) 1.54
Characterization of apolipoprotein J-Alzheimer's A beta interaction. J Biol Chem (1995) 1.53
Clearance of amyloid beta-peptide from brain: transport or metabolism? Nat Med (2000) 1.53
Outcomes in locally advanced rectal cancer with highly selective preoperative chemoradiotherapy. Br J Surg (2014) 1.52
Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1- 40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer. J Clin Invest (1998) 1.51
Peptides homologous to the amyloid protein of Alzheimer's disease containing a glutamine for glutamic acid substitution have accelerated amyloid fibril formation. Biochem Biophys Res Commun (1991) 1.51
Sulfated glycans stimulate endocytosis of the cellular isoform of the prion protein, PrPC, in cultured cells. J Biol Chem (1995) 1.51
Malignant peripheral nerve sheath tumors associated with neurofibromatosis type 1: a clinicopathologic and molecular study of 17 patients. Arch Dermatol (2001) 1.50
Pall leukotrap affinity prion-reduction filter removes exogenous infectious prions and endogenous infectivity from red cell concentrates. Vox Sang (2006) 1.50
Mutation in gelsolin gene in Finnish hereditary amyloidosis. J Exp Med (1990) 1.50
Immunochemical similarities between monoclonal antibacterial Waldenstrom's macroglobulins and monoclonal anti-DNA lupus autoantibodies. J Exp Med (1985) 1.49