Published in J Virol on September 01, 1986
Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins. J Virol (1987) 7.05
Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy. J Virol (1994) 5.12
Biochemical and physical properties of the prion protein from two strains of the transmissible mink encephalopathy agent. J Virol (1992) 4.02
Strain-specified relative conformational stability of the scrapie prion protein. Protein Sci (2001) 2.60
Analyses of frequency of infection, specific infectivity, and prion protein biosynthesis in scrapie-infected neuroblastoma cell clones. J Virol (1988) 1.92
Molecular location of a species-specific epitope on the hamster scrapie agent protein. J Virol (1991) 1.89
The strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of disease. PLoS Pathog (2011) 1.49
Cellular biology of prion diseases. Clin Microbiol Rev (1999) 1.48
Characterization of truncated forms of abnormal prion protein in Creutzfeldt-Jakob disease. J Biol Chem (2008) 1.40
The prion strain phenomenon: molecular basis and unprecedented features. Biochim Biophys Acta (2006) 1.39
Antisera to scrapie-associated fibril protein and prion protein decorate scrapie-associated fibrils. J Virol (1987) 1.35
Incidence and spectrum of sporadic Creutzfeldt-Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification. Acta Neuropathol (2009) 1.32
Comparison of abnormal prion protein glycoform patterns from transmissible spongiform encephalopathy agent-infected deer, elk, sheep, and cattle. J Virol (2002) 1.30
Molecular analysis of the abnormal prion protein during coinfection of mice by bovine spongiform encephalopathy and a scrapie agent. J Virol (2001) 1.28
Clearance and prevention of prion infection in cell culture by anti-PrP antibodies. Eur J Neurosci (2006) 1.22
Molecular analysis of the protease-resistant prion protein in scrapie and bovine spongiform encephalopathy transmitted to ovine transgenic and wild-type mice. J Virol (2004) 1.20
Anti-PrP Mab 6D11 suppresses PrP(Sc) replication in prion infected myeloid precursor line FDC-P1/22L and in the lymphoreticular system in vivo. Neurobiol Dis (2009) 1.00
Prion strain targeting independent of strain-specific neuronal tropism. J Virol (2008) 0.97
Biochemical fingerprints of prion infection: accumulations of aberrant full-length and N-terminally truncated PrP species are common features in mouse prion disease. J Virol (2005) 0.95
Glycan-controlled epitopes of prion protein include a major determinant of susceptibility to sheep scrapie. J Virol (2004) 0.92
Antiserum to scrapie-associated fibril protein cross-reacts with Spiroplasma mirum fibril proteins. J Clin Microbiol (1987) 0.92
Immunological analysis of host and agent effects on Creutzfeldt-Jakob disease and scrapie prion proteins. J Virol (1988) 0.88
Preparation and characterization of antibodies against mouse prion protein (PrP) peptides. Clin Diagn Lab Immunol (1995) 0.86
Identification and characterization of proteinase K-resistant proteins in members of the class Mollicutes. Infect Immun (1991) 0.86
Rapid typing of transmissible spongiform encephalopathy strains with differential ELISA. Emerg Infect Dis (2008) 0.85
The comparative immunoreactivities of brain amyloids in Alzheimer's disease and scrapie. Acta Neuropathol (1987) 0.84
Prion protein misfolding, strains, and neurotoxicity: an update from studies on Mammalian prions. Int J Cell Biol (2013) 0.82
T-Tau and P-Tau in Brain and Blood from Natural and Experimental Prion Diseases. PLoS One (2015) 0.81
PrP antibody binding-induced epitope modulation evokes immunocooperativity. J Neuroimmunol (2008) 0.80
Breaking an absolute species barrier: transgenic mice expressing the mink PrP gene are susceptible to transmissible mink encephalopathy. J Virol (2005) 0.80
A comparative study of modified confirmatory techniques and additional immuno-based methods for non-conclusive autolytic bovine spongiform encephalopathy cases. BMC Vet Res (2013) 0.78
Transgenic over-expression of mammalian heparanase delays prion disease onset and progression. Biochem Biophys Res Commun (2015) 0.76
PrPSc-Specific Antibody Reveals C-Terminal Conformational Differences between Prion Strains. J Virol (2016) 0.75
Role of CD40 in prion disease and the immune response to recombinant PrP. J Neuroimmunol (2013) 0.75
Altered lymphocyte proliferation and innate immune function in scrapie 139A- and ME7-infected mice. Viral Immunol (2013) 0.75
Immune electron microscopic characterization of monoclonal antibodies to Alzheimer neurofibrillary tangles. Am J Pathol (1992) 0.75
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A (1979) 365.71
Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc Natl Acad Sci U S A (1985) 16.10
Rapid and sensitive colorimetric method for visualizing biotin-labeled DNA probes hybridized to DNA or RNA immobilized on nitrocellulose: Bio-blots. Proc Natl Acad Sci U S A (1983) 12.81
Affinity purification of antibodies from diazotized paper blots of heterogeneous protein samples. J Biol Chem (1981) 9.11
A cellular gene encodes scrapie PrP 27-30 protein. Cell (1985) 8.86
Scrapie prions aggregate to form amyloid-like birefringent rods. Cell (1983) 7.92
Identification of a protein that purifies with the scrapie prion. Science (1982) 7.00
A protease-resistant protein is a structural component of the scrapie prion. Cell (1983) 6.72
Purification and structural studies of a major scrapie prion protein. Cell (1984) 5.98
Abnormal fibrils from scrapie-infected brain. Acta Neuropathol (1981) 5.35
Separation and properties of cellular and scrapie prion proteins. Proc Natl Acad Sci U S A (1986) 4.38
Further purification and characterization of scrapie prions. Biochemistry (1982) 4.01
Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain. Nature (1985) 3.38
Scrapie infectivity, fibrils and low molecular weight protein. Nature (1984) 3.18
Antibodies to a scrapie prion protein. Nature (1984) 3.09
Identification of prion amyloid filaments in scrapie-infected brain. Cell (1985) 3.04
Alzheimer paired helical filaments: immunochemical identification of polypeptides. Acta Neuropathol (1984) 2.70
Scrapie PrP 27-30 is a sialoglycoprotein. J Virol (1985) 2.40
Infection-specific particle from the unconventional slow virus diseases. Science (1984) 2.34
Ultrastructural morphology of amyloid fibrils from neuritic and amyloid plaques. Acta Neuropathol (1983) 2.23
Scrapie-associated fibrils in Creutzfeldt-Jakob disease. Nature (1984) 2.11
Clinical and pathological features and laboratory confirmation of Creutzfeldt-Jakob disease in a recipient of pituitary-derived human growth hormone. N Engl J Med (1985) 2.09
Creutzfeldt-Jakob disease prion proteins in human brains. N Engl J Med (1985) 2.04
Specific proteins associated with Creutzfeldt-Jakob disease and scrapie share antigenic and carbohydrate determinants. Proc Natl Acad Sci U S A (1985) 1.99
A rapid and efficient method to enrich SAF-protein from scrapie brains of hamsters. Biosci Rep (1984) 1.94
The protein component of scrapie-associated fibrils is a glycosylated low molecular weight protein. EMBO J (1985) 1.76
Biochemical differences among scrapie-associated fibrils support the biological diversity of scrapie agents. J Gen Virol (1985) 1.75
Detection of scrapie-associated fibril (SAF) proteins using anti-SAF antibody in non-purified tissue preparations. J Gen Virol (1986) 1.67
Molecular characteristics of the major scrapie prion protein. Biochemistry (1984) 1.64
Antibodies to the scrapie protein decorate prion rods. J Immunol (1985) 1.46
Use of lectins for detection of electrophoretically separated glycoproteins transferred onto nitrocellulose sheets. Anal Biochem (1981) 1.45
Characterization of antisera against scrapie-associated fibrils (SAF) from affected hamster and cross-reactivity with SAF from scrapie-affected mice and from patients with Creutzfeldt-Jakob disease. J Gen Virol (1985) 1.38
Some speculations about prions, amyloid, and Alzheimer's disease. N Engl J Med (1984) 1.35
Genetical control of the concentration of ME7 scrapie agent in the brain of mice. J Comp Pathol (1969) 1.28
Partial copurification of scrapie-associated fibrils and scrapie infectivity. Intervirology (1986) 1.10
Influenza virus transcription. J Gen Virol (1978) 1.09
In vitro interaction of scrapie agent and mouse peritoneal macrophages. Intervirology (1981) 1.01
Paired helical filaments associated with Alzheimer disease are readily soluble structures. Brain Res (1986) 1.00
A 54-kDa normal cellular protein may be the precursor of the scrapie agent protease-resistant protein. Proc Natl Acad Sci U S A (1986) 0.91
Comparison of RNA from healthy and scrapie-infected hamster brain. J Gen Virol (1985) 0.85
Ultrastructural links between scrapie and Alzheimer's disease. Lancet (1985) 0.83
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. Proc Natl Acad Sci U S A (1986) 10.13
Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins. J Virol (1987) 7.05
Microtubule-associated protein tau. A component of Alzheimer paired helical filaments. J Biol Chem (1986) 6.91
Abnormal fibrils from scrapie-infected brain. Acta Neuropathol (1981) 5.35
Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides. Proc Natl Acad Sci U S A (1987) 3.97
Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome. Ann Neurol (1985) 3.83
The histological validation of post mortem magnetic resonance imaging-determined hippocampal volume in Alzheimer's disease. Neuroscience (2000) 3.40
Scrapie infectivity, fibrils and low molecular weight protein. Nature (1984) 3.18
Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease. Brain Res (1989) 3.10
Mutations in familial Creutzfeldt-Jakob disease and Gerstmann-Sträussler-Scheinker's syndrome. Exp Neurol (1989) 3.00
Alzheimer paired helical filaments: bulk isolation, solubility, and protein composition. Acta Neuropathol (1984) 2.97
Molecular assessment of the potential transmissibilities of BSE and scrapie to humans. Nature (1997) 2.80
Alzheimer paired helical filaments: immunochemical identification of polypeptides. Acta Neuropathol (1984) 2.70
Frequency of hippocampal formation atrophy in normal aging and Alzheimer's disease. Neurobiol Aging (1997) 2.68
Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease. Arch Neurol (2000) 2.66
Alzheimer neurofibrillary tangles: monoclonal antibodies to inherent antigen(s). Acta Neuropathol (1984) 2.58
Further studies of blood infectivity in an experimental model of transmissible spongiform encephalopathy, with an explanation of why blood components do not transmit Creutzfeldt-Jakob disease in humans. Transfusion (2000) 2.52
Alzheimer neurofibrillary tangles in diseases other than senile and presenile dementia. Ann Neurol (1979) 2.50
Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes. J Virol (1991) 2.47
Infection-specific particle from the unconventional slow virus diseases. Science (1984) 2.34
Ultrastructural morphology of amyloid fibrils from neuritic and amyloid plaques. Acta Neuropathol (1983) 2.23
Evidence that Alzheimer neurofibrillary tangles originate from neurotubules. Lancet (1979) 2.22
A comparison of the replication cycles of simian virus 40 in human diploid and African green monkey kidney cells. Virology (1966) 2.13
Scrapie-associated fibrils in Creutzfeldt-Jakob disease. Nature (1984) 2.11
Growth of murine cytomegalovirus in various cell lines. J Virol (1971) 2.06
Cellular isoform of the scrapie agent protein participates in lymphocyte activation. Cell (1990) 2.06
Nearly ubiquitous tissue distribution of the scrapie agent precursor protein. Neurology (1992) 2.00
Plasma amyloid beta-peptide 1-42 and incipient Alzheimer's disease. Ann Neurol (1999) 1.96
A rapid and efficient method to enrich SAF-protein from scrapie brains of hamsters. Biosci Rep (1984) 1.94
The inactivation of simian virus 40 infectivity and antigen-inducing capacity by ultraviolet light. Virology (1965) 1.93
Molecular location of a species-specific epitope on the hamster scrapie agent protein. J Virol (1991) 1.89
Defective brain microtubule assembly in Alzheimer's disease. Lancet (1986) 1.89
Dextran sulphate 500 delays and prevents mouse scrapie by impairment of agent replication in spleen. J Gen Virol (1984) 1.87
MRI of entorhinal cortex in mild Alzheimer's disease. Lancet (1999) 1.86
Ultrastructure of paired helical filaments of Alzheimer's neurofibrillary tangle. J Neuropathol Exp Neurol (1984) 1.86
Tissue handling in suspected Creutzfeldt-Jakob disease (CJD) and other human spongiform encephalopathies (prion diseases) Brain Pathol (1995) 1.86
In vitro replication of scrapie agent in a neuronal model: infection of PC12 cells. J Gen Virol (1984) 1.80
Adult fragile X syndrome. Clinico-neuropathologic findings. Acta Neuropathol (1985) 1.80
The effect of actinomycin D on the transcription and replication of simian virus 40 deoxyribonucleic acid. Virology (1969) 1.78
The distribution of Ia antigen in the lesions of rat acute experimental allergic encephalomyelitis. Acta Neuropathol (1986) 1.77
The protein component of scrapie-associated fibrils is a glycosylated low molecular weight protein. EMBO J (1985) 1.76
Alzheimer's disease in Down's syndrome: clinicopathologic studies. Neurology (1985) 1.75
Biochemical differences among scrapie-associated fibrils support the biological diversity of scrapie agents. J Gen Virol (1985) 1.75
Isolation of a cDNA clone encoding the leader peptide of prion protein and expression of the homologous gene in various tissues. Proc Natl Acad Sci U S A (1986) 1.75
Antiviral activity of arildone on deoxyribonucleic acid and ribonucleic acid viruses. Antimicrob Agents Chemother (1980) 1.75
Presenilin-1 forms complexes with the cadherin/catenin cell-cell adhesion system and is recruited to intercellular and synaptic contacts. Mol Cell (1999) 1.74
Early spread of scrapie from the gastrointestinal tract to the central nervous system involves autonomic fibers of the splanchnic and vagus nerves. J Virol (2001) 1.73
Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils. Acta Neuropathol (1992) 1.71
Spongiform encephalopathy in free-ranging mule deer (Odocoileus hemionus), white-tailed deer (Odocoileus virginianus) and Rocky Mountain elk (Cervus elaphus nelsoni) in northcentral Colorado. J Wildl Dis (1997) 1.69
Relationships between regional neuronal loss and neurofibrillary changes in the hippocampal formation and duration and severity of Alzheimer disease. J Neuropathol Exp Neurol (1997) 1.67
Detection of scrapie-associated fibril (SAF) proteins using anti-SAF antibody in non-purified tissue preparations. J Gen Virol (1986) 1.67
Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex. Proc Natl Acad Sci U S A (2001) 1.67
Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie. J Clin Invest (2001) 1.66
Sequential appearance and accumulation of pathognomonic markers in the central nervous system of hamsters orally infected with scrapie. J Gen Virol (1996) 1.61
Morphology and distribution of Alzheimer neuritic (senile) and amyloid plaques in striatum and diencephalon. Acta Neuropathol (1984) 1.60
Primary demyelination as a nonspecific consequence of a cell-mediated immune reaction. J Exp Med (1975) 1.57
Evidence for induction of localized amyloid deposits and neuritic plaques by an infectious agent. Ann Neurol (1981) 1.56
Analysis of structural polypeptides of purified human cytomegalovirus. J Virol (1976) 1.55
Reversion of prion protein conformational changes by synthetic beta-sheet breaker peptides. Lancet (2000) 1.54
Blood infectivity and the prospects for a diagnostic screening test in Creutzfeldt-Jakob disease. J Lab Clin Med (2001) 1.53
Microtubule-associated polypeptides tau are altered in Alzheimer paired helical filaments. Brain Res (1988) 1.51
An antigenic profile of Lewy bodies: immunocytochemical indication for protein phosphorylation and ubiquitination. J Neuropathol Exp Neurol (1989) 1.51
Iatrogenic Creutzfeldt-Jakob disease: an example of the interplay between ancient genes and modern medicine. Neurology (1994) 1.50
Pall leukotrap affinity prion-reduction filter removes exogenous infectious prions and endogenous infectivity from red cell concentrates. Vox Sang (2006) 1.50
A comparative study of histological and immunohistochemical methods for neurofibrillary tangles and senile plaques in Alzheimer's disease. Acta Neuropathol (1992) 1.49
Decreased percentage of polymorphonuclear neutrophils in mouse peripheral blood after inoculation with material from multiple sclerosis patients. J Exp Med (1972) 1.49
A direct relationship between the partitioning of the pathogenic prion protein and transmissible spongiform encephalopathy infectivity during the purification of plasma proteins. Transfusion (2001) 1.49
Changes in phosphatidylinositol metabolism correlated to growth state of normal and Rous sarcoma virus-transformed Japanese quail cells. Cancer Res (1977) 1.48
Substructures of paired helical filaments from Alzheimer's disease neurofibrillary tangles. Acta Neuropathol (1985) 1.48