Detection of scrapie-associated fibril (SAF) proteins using anti-SAF antibody in non-purified tissue preparations.

PubWeight™: 1.67‹?› | Rank: Top 3%

🔗 View Article (PMID 2420924)

Published in J Gen Virol on April 01, 1986

Authors

R Rubenstein, R J Kascsak, P A Merz, M C Papini, R I Carp, N K Robakis, H M Wisniewski

Articles citing this

Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins. J Virol (1987) 7.05

Species specificity in the cell-free conversion of prion protein to protease-resistant forms: a model for the scrapie species barrier. Proc Natl Acad Sci U S A (1995) 2.58

Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes. J Virol (1991) 2.47

Immunohistochemical detection of prion protein in lymphoid tissues of sheep with natural scrapie. J Clin Microbiol (1996) 2.26

The major polypeptide of scrapie-associated fibrils (SAF) has the same size, charge distribution and N-terminal protein sequence as predicted for the normal brain protein (PrP). EMBO J (1986) 2.19

Prion protein biosynthesis in scrapie-infected and uninfected neuroblastoma cells. J Virol (1989) 2.08

Immunological comparison of scrapie-associated fibrils isolated from animals infected with four different scrapie strains. J Virol (1986) 1.95

Analyses of frequency of infection, specific infectivity, and prion protein biosynthesis in scrapie-infected neuroblastoma cell clones. J Virol (1988) 1.92

Abnormal isoform of prion protein accumulates in follicular dendritic cells in mice with Creutzfeldt-Jakob disease. J Virol (1991) 1.90

Isolation of a cDNA clone encoding the leader peptide of prion protein and expression of the homologous gene in various tissues. Proc Natl Acad Sci U S A (1986) 1.75

The sequential development of abnormal prion protein accumulation in mice with Creutzfeldt-Jakob disease. Am J Pathol (1992) 1.66

Antisera to scrapie-associated fibril protein and prion protein decorate scrapie-associated fibrils. J Virol (1987) 1.35

Normal and scrapie-associated forms of prion protein differ in their sensitivities to phospholipase and proteases in intact neuroblastoma cells. J Virol (1990) 1.24

Prion liposomes. Biochem J (1990) 1.23

In vitro expression in eukaryotic cells of a prion protein gene cloned from scrapie-infected mouse brain. Proc Natl Acad Sci U S A (1988) 1.04

Opposite effects of dextran sulfate 500, the polyene antibiotic MS-8209, and Congo red on accumulation of the protease-resistant isoform of PrP in the spleens of mice inoculated intraperitoneally with the scrapie agent. J Virol (2000) 0.97

Antiserum to scrapie-associated fibril protein cross-reacts with Spiroplasma mirum fibril proteins. J Clin Microbiol (1987) 0.92

Immunological analysis of host and agent effects on Creutzfeldt-Jakob disease and scrapie prion proteins. J Virol (1988) 0.88

Preparation and characterization of antibodies against mouse prion protein (PrP) peptides. Clin Diagn Lab Immunol (1995) 0.86

Dissociation between transmissible spongiform encephalopathy (TSE) infectivity and proteinase K-resistant PrP(Sc) levels in peripheral tissue from a murine transgenic model of TSE disease. J Virol (2013) 0.84

Pathogenic mutations within the hydrophobic domain of the prion protein lead to the formation of protease-sensitive prion species with increased lethality. J Virol (2013) 0.78

Articles by these authors

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. Proc Natl Acad Sci U S A (1986) 10.13

Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins. J Virol (1987) 7.05

Microtubule-associated protein tau. A component of Alzheimer paired helical filaments. J Biol Chem (1986) 6.91

Abnormal fibrils from scrapie-infected brain. Acta Neuropathol (1981) 5.35

Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides. Proc Natl Acad Sci U S A (1987) 3.97

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome. Ann Neurol (1985) 3.83

The histological validation of post mortem magnetic resonance imaging-determined hippocampal volume in Alzheimer's disease. Neuroscience (2000) 3.40

Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease. Brain Res (1989) 3.10

Mutations in familial Creutzfeldt-Jakob disease and Gerstmann-Sträussler-Scheinker's syndrome. Exp Neurol (1989) 3.00

Alzheimer paired helical filaments: bulk isolation, solubility, and protein composition. Acta Neuropathol (1984) 2.97

Molecular assessment of the potential transmissibilities of BSE and scrapie to humans. Nature (1997) 2.80

Alzheimer paired helical filaments: immunochemical identification of polypeptides. Acta Neuropathol (1984) 2.70

Frequency of hippocampal formation atrophy in normal aging and Alzheimer's disease. Neurobiol Aging (1997) 2.68

Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease. Arch Neurol (2000) 2.66

Alzheimer neurofibrillary tangles: monoclonal antibodies to inherent antigen(s). Acta Neuropathol (1984) 2.58

Further studies of blood infectivity in an experimental model of transmissible spongiform encephalopathy, with an explanation of why blood components do not transmit Creutzfeldt-Jakob disease in humans. Transfusion (2000) 2.52

Alzheimer neurofibrillary tangles in diseases other than senile and presenile dementia. Ann Neurol (1979) 2.50

Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes. J Virol (1991) 2.47

Chromosome 21q21 sublocalisation of gene encoding beta-amyloid peptide in cerebral vessels and neuritic (senile) plaques of people with Alzheimer disease and Down syndrome. Lancet (1987) 2.44

Infection-specific particle from the unconventional slow virus diseases. Science (1984) 2.34

Ultrastructural morphology of amyloid fibrils from neuritic and amyloid plaques. Acta Neuropathol (1983) 2.23

Evidence that Alzheimer neurofibrillary tangles originate from neurotubules. Lancet (1979) 2.22

A comparison of the replication cycles of simian virus 40 in human diploid and African green monkey kidney cells. Virology (1966) 2.13

Scrapie-associated fibrils in Creutzfeldt-Jakob disease. Nature (1984) 2.11

Growth of murine cytomegalovirus in various cell lines. J Virol (1971) 2.06

Cellular isoform of the scrapie agent protein participates in lymphocyte activation. Cell (1990) 2.06

Nearly ubiquitous tissue distribution of the scrapie agent precursor protein. Neurology (1992) 2.00

Plasma amyloid beta-peptide 1-42 and incipient Alzheimer's disease. Ann Neurol (1999) 1.96

Immunological comparison of scrapie-associated fibrils isolated from animals infected with four different scrapie strains. J Virol (1986) 1.95

The inactivation of simian virus 40 infectivity and antigen-inducing capacity by ultraviolet light. Virology (1965) 1.93

Molecular location of a species-specific epitope on the hamster scrapie agent protein. J Virol (1991) 1.89

Defective brain microtubule assembly in Alzheimer's disease. Lancet (1986) 1.89

MRI of entorhinal cortex in mild Alzheimer's disease. Lancet (1999) 1.86

Ultrastructure of paired helical filaments of Alzheimer's neurofibrillary tangle. J Neuropathol Exp Neurol (1984) 1.86

In vitro replication of scrapie agent in a neuronal model: infection of PC12 cells. J Gen Virol (1984) 1.80

Adult fragile X syndrome. Clinico-neuropathologic findings. Acta Neuropathol (1985) 1.80

The effect of actinomycin D on the transcription and replication of simian virus 40 deoxyribonucleic acid. Virology (1969) 1.78

The distribution of Ia antigen in the lesions of rat acute experimental allergic encephalomyelitis. Acta Neuropathol (1986) 1.77

Alzheimer's disease in Down's syndrome: clinicopathologic studies. Neurology (1985) 1.75

Biochemical differences among scrapie-associated fibrils support the biological diversity of scrapie agents. J Gen Virol (1985) 1.75

Isolation of a cDNA clone encoding the leader peptide of prion protein and expression of the homologous gene in various tissues. Proc Natl Acad Sci U S A (1986) 1.75

Antiviral activity of arildone on deoxyribonucleic acid and ribonucleic acid viruses. Antimicrob Agents Chemother (1980) 1.75

Presenilin-1 forms complexes with the cadherin/catenin cell-cell adhesion system and is recruited to intercellular and synaptic contacts. Mol Cell (1999) 1.74

Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils. Acta Neuropathol (1992) 1.71

Spongiform encephalopathy in free-ranging mule deer (Odocoileus hemionus), white-tailed deer (Odocoileus virginianus) and Rocky Mountain elk (Cervus elaphus nelsoni) in northcentral Colorado. J Wildl Dis (1997) 1.69

Relationships between regional neuronal loss and neurofibrillary changes in the hippocampal formation and duration and severity of Alzheimer disease. J Neuropathol Exp Neurol (1997) 1.67

Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex. Proc Natl Acad Sci U S A (2001) 1.67

Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie. J Clin Invest (2001) 1.66

Morphology and distribution of Alzheimer neuritic (senile) and amyloid plaques in striatum and diencephalon. Acta Neuropathol (1984) 1.60

Primary demyelination as a nonspecific consequence of a cell-mediated immune reaction. J Exp Med (1975) 1.57

Evidence for induction of localized amyloid deposits and neuritic plaques by an infectious agent. Ann Neurol (1981) 1.56

Analysis of structural polypeptides of purified human cytomegalovirus. J Virol (1976) 1.55

Reversion of prion protein conformational changes by synthetic beta-sheet breaker peptides. Lancet (2000) 1.54

Microtubule-associated polypeptides tau are altered in Alzheimer paired helical filaments. Brain Res (1988) 1.51

An antigenic profile of Lewy bodies: immunocytochemical indication for protein phosphorylation and ubiquitination. J Neuropathol Exp Neurol (1989) 1.51

Iatrogenic Creutzfeldt-Jakob disease: an example of the interplay between ancient genes and modern medicine. Neurology (1994) 1.50

Pall leukotrap affinity prion-reduction filter removes exogenous infectious prions and endogenous infectivity from red cell concentrates. Vox Sang (2006) 1.50

A direct relationship between the partitioning of the pathogenic prion protein and transmissible spongiform encephalopathy infectivity during the purification of plasma proteins. Transfusion (2001) 1.49

A comparative study of histological and immunohistochemical methods for neurofibrillary tangles and senile plaques in Alzheimer's disease. Acta Neuropathol (1992) 1.49

Decreased percentage of polymorphonuclear neutrophils in mouse peripheral blood after inoculation with material from multiple sclerosis patients. J Exp Med (1972) 1.49

Substructures of paired helical filaments from Alzheimer's disease neurofibrillary tangles. Acta Neuropathol (1985) 1.48

Creutzfeldt-Jacob disease associated with the PRNP codon 200Lys mutation: an analysis of 45 families. Eur J Epidemiol (1991) 1.48

Scrapie-associated prion protein accumulates in astrocytes during scrapie infection. Proc Natl Acad Sci U S A (1991) 1.45

Abortive infection of human diploid cells by murine cytomegalovirus. Infect Immun (1972) 1.43

Amyloid protein and neurofibrillary tangles coexist in the same neuron in Alzheimer disease. Proc Natl Acad Sci U S A (1989) 1.40

Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ. Acta Neuropathol (1995) 1.40

Alzheimer disease (AD): aspirin prophylaxis and therapy. Alzheimer Dis Assoc Disord (1992) 1.39

Alzheimer neurofibrillary tangles: antiserum and immunohistological staining. Ann Neurol (1979) 1.39

Genetic and molecular aspects of Alzheimer's disease shed light on new mechanisms of transcriptional regulation. Genes Brain Behav (2005) 1.36

Alzheimer paired helical filaments: cross-reacting polypeptide/s normally present in brain. Acta Neuropathol (1985) 1.36

Neurofibrillary tangles in Alzheimer's disease and progressive supranuclear palsy: antigenic similarities and differences. Microtubule-associated protein tau antigenicity is prominent in all types of tangles. Acta Neuropathol (1987) 1.35

Antisera to scrapie-associated fibril protein and prion protein decorate scrapie-associated fibrils. J Virol (1987) 1.35