Keratinocyte growth regulation in fibroblast cocultures via a double paracrine mechanism.

PubWeight™: 1.52‹?› | Rank: Top 4%

🔗 View Article (PMID 10341204)

Published in J Cell Sci on June 01, 1999

Authors

N Maas-Szabowski1, A Shimotoyodome, N E Fusenig

Author Affiliations

1: Division of Differentiation and Carcinogenesis, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Articles citing this

Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation. Am J Pathol (2002) 2.23

Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients. J Clin Invest (2007) 1.73

Myofibroblast differentiation is induced in keratinocyte-fibroblast co-cultures and is antagonistically regulated by endogenous transforming growth factor-beta and interleukin-1. Am J Pathol (2004) 1.39

Targeted expression of RALT in mouse skin inhibits epidermal growth factor receptor signalling and generates a Waved-like phenotype. EMBO Rep (2005) 1.11

Novel p63 target genes involved in paracrine signaling and keratinocyte differentiation. Cell Death Dis (2010) 1.08

Interleukin-1 as a phenotypic immunomodulator in keratinizing squamous metaplasia of the ocular surface in Sjögren's syndrome. Am J Pathol (2010) 1.02

Cholesteatoma fibroblasts promote epithelial cell proliferation through overexpression of epiregulin. PLoS One (2013) 0.99

MDI 301, a non-irritating retinoid, induces changes in human skin that underlie repair. Arch Dermatol Res (2006) 0.96

Protective effect of pomegranate-derived products on UVB-mediated damage in human reconstituted skin. Exp Dermatol (2009) 0.95

Agent based modelling helps in understanding the rules by which fibroblasts support keratinocyte colony formation. PLoS One (2008) 0.93

A decisive function of transforming growth factor-β/Smad signaling in tissue morphogenesis and differentiation of human HaCaT keratinocytes. Mol Biol Cell (2011) 0.92

Long-term maintenance of limbal epithelial progenitor cells using rho kinase inhibitor and keratinocyte growth factor. Stem Cells Transl Med (2013) 0.91

Regulation of cell proliferation and migration by TAK1 via transcriptional control of von Hippel-Lindau tumor suppressor. J Biol Chem (2009) 0.89

The Roles of Growth Factors in Keratinocyte Migration. Adv Wound Care (New Rochelle) (2015) 0.88

Naturally Occurring Extracellular Matrix Scaffolds for Dermal Regeneration: Do They Really Need Cells? Biomed Res Int (2015) 0.88

Inactivation of Rb in stromal fibroblasts promotes epithelial cell invasion. EMBO J (2012) 0.86

Keratinocyte stimulation of matrix metalloproteinase-1 production and proliferation in fibroblasts: regulation through mitogen-activated protein kinase signalling events. Br J Cancer (2002) 0.85

Inhibition of proliferation and migration of stricture fibroblasts by epithelial cell-conditioned media. Indian J Urol (2015) 0.85

Skin fragility and impaired desmosomal adhesion in mice lacking all keratins. J Invest Dermatol (2013) 0.84

Dermal fibroblast expression of stromal cell-derived factor-1 (SDF-1) promotes epidermal keratinocyte proliferation in normal and diseased skin. Protein Cell (2015) 0.84

Induction of matrix metalloproteinase-1 (MMP-1) during epidermal invasion of the stroma in human skin organ culture: keratinocyte stimulation of fibroblast MMP-1 production. Br J Cancer (2001) 0.81

Modulation of the keratinocyte-fibroblast paracrine relationship with gelatin-based semi-interpenetrating networks containing bioactive factors for wound repair. J Biomater Sci Polym Ed (2009) 0.81

Efficient keratinocyte differentiation strictly depends on JNK-induced soluble factors in fibroblasts. J Invest Dermatol (2013) 0.81

Combined deletion of p38γ and p38δ reduces skin inflammation and protects from carcinogenesis. Oncotarget (2015) 0.81

The effects of TGF-alpha, IL-1beta and PDGF on fibroblast adhesion to ECM-derived matrix and KGF gene expression. Biomaterials (2009) 0.81

Effects of honeybee (Apis mellifera) venom on keratinocyte migration in vitro. Pharmacogn Mag (2013) 0.81

AKT in stromal fibroblasts controls invasion of epithelial cells. Oncotarget (2013) 0.81

Immunohistochemical Expression of PCNA in Epithelial Linings of Selected Odontogenic Lesions. J Clin Diagn Res (2013) 0.80

Recessive epidermolysis bullosa simplex phenotype reproduced in vitro: ablation of keratin 14 is partially compensated by keratin 17. Am J Pathol (2003) 0.80

Immunomodulation of skin cytokine secretion by house dust mite extracts. Int Arch Allergy Immunol (2011) 0.80

Regulation of epithelial differentiation and proliferation by the stroma: a role for the retinoblastoma protein. J Invest Dermatol (2012) 0.79

TNFα modulates Fibroblast Growth Factor Receptor 2 gene expression through the pRB/E2F1 pathway: identification of a non-canonical E2F binding motif. PLoS One (2013) 0.79

Micropatterned dermal-epidermal regeneration matrices create functional niches that enhance epidermal morphogenesis. Acta Biomater (2013) 0.77

Mechanical Stretch on Human Skin Equivalents Increases the Epidermal Thickness and Develops the Basement Membrane. PLoS One (2015) 0.77

Concentration of fibrin and presence of plasminogen affect proliferation, fibrinolytic activity, and morphology of human fibroblasts and keratinocytes in 3D fibrin constructs. Tissue Eng Part A (2014) 0.75

Characterization of A Three-Dimensional Organotypic Co-Culture Skin Model for Epidermal Differentiation of Rat Adipose-Derived Stem Cells. Cell J (2016) 0.75

Inducing re-epithelialization in skin wound through cultured oral mucosal keratinocytes. J Korean Assoc Oral Maxillofac Surg (2013) 0.75

Cultured Human Epidermis Combined With Meshed Skin Autografts Accelerates Epithelialization and Granulation Tissue Formation in a Rat Model. Ann Plast Surg (2017) 0.75

Generation of a three-dimensional full thickness skin equivalent and automated wounding. J Vis Exp (2015) 0.75

Human skin organ culture for assessment of chemically induced skin damage. Expert Rev Dermatol (2012) 0.75

Articles by these authors

(truncated to the top 100)

Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol (1988) 16.82

Molecular and cytogenetic analysis of immortalized human primary keratinocytes obtained after transfection with human papillomavirus type 16 DNA. Oncogene (1987) 4.02

Halting angiogenesis suppresses carcinoma cell invasion. Nat Med (1997) 2.61

Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization. Nat Med (1998) 2.54

c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin. Cell (2000) 2.35

The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategies. J Cell Biol (2001) 1.94

Tumorigenic conversion of immortal human keratinocytes through stromal cell activation. Proc Natl Acad Sci U S A (1998) 1.82

Simultaneous expression of two different types of intermediate sized filaments in mouse keratinocytes proliferating in vitro. Differentiation (1979) 1.68

Mutual induction of growth factor gene expression by epidermal-dermal cell interaction. J Cell Biol (1993) 1.60

c-Ha-ras oncogene expression in immortalized human keratinocytes (HaCaT) alters growth potential in vivo but lacks correlation with malignancy. Cancer Res (1990) 1.59

Epidermal organization and differentiation of HaCaT keratinocytes in organotypic coculture with human dermal fibroblasts. J Invest Dermatol (1999) 1.51

Expression of collagenase-3 (MMP-13) and collagenase-1 (MMP-1) by transformed keratinocytes is dependent on the activity of p38 mitogen-activated protein kinase. J Cell Sci (2000) 1.50

Phenotypic and genotypic characteristics of a cell line from a squamous cell carcinoma of human skin. J Natl Cancer Inst (1982) 1.49

Reformation of organized epidermal structure by transplantation of suspensions and cultures of epidermal and dermal cells. Cell Tissue Res (1982) 1.45

Keratinocyte growth regulation in defined organotypic cultures through IL-1-induced keratinocyte growth factor expression in resting fibroblasts. J Invest Dermatol (2000) 1.43

Preservation of morphological, functional, and karyotypic traits during long-term culture and in vivo passage of two human skin squamous cell carcinomas. Cancer Res (1983) 1.42

Environmental modulation of the expression of differentiation and malignancy in six human squamous cell carcinoma cell lines. Cancer Res (1985) 1.40

Epithelial-mesenchymal interactions control basement membrane production and differentiation in cultured and transplanted mouse keratinocytes. Cell Tissue Res (1986) 1.39

Differentiation specific functions in cultured and transplanted mouse keratinocytes: environmental influences on ultrastructure and keratin expression. Differentiation (1984) 1.39

Mouse epidermal cell cultures. II. Isolation, characterization and cultivation of epidermal cells from perinatal mouse skin. Exp Cell Res (1975) 1.39

Effect of growth environment on spatial expression of involucrin by human epidermal keratinocytes. Arch Dermatol Res (1987) 1.36

Growth and differentiation characteristics of transformed keratinocytes from mouse and human skin in vitro and in vivo. J Invest Dermatol (1983) 1.36

Dynamics of basement membrane formation by keratinocyte-fibroblast interactions in organotypic skin culture. Exp Cell Res (1998) 1.33

Sustained nontumorigenic phenotype correlates with a largely stable chromosome content during long-term culture of the human keratinocyte line HaCaT. Genes Chromosomes Cancer (1997) 1.32

Organotypic keratinocyte cocultures in defined medium with regular epidermal morphogenesis and differentiation. J Invest Dermatol (1999) 1.32

Allele-specific methylation of the human c-Ha-ras-1 gene. Cell (1987) 1.31

Density-dependent modulation of synthesis of keratins 1 and 10 in the human keratinocyte line HACAT and in ras-transfected tumorigenic clones. Differentiation (1989) 1.30

Proteolytic modification of acidic and basic keratins during terminal differentiation of mouse and human epidermis. Eur J Biochem (1984) 1.28

Tumor progression of skin carcinoma cells in vivo promoted by clonal selection, mutagenesis, and autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor. Am J Pathol (2001) 1.23

Epidermal differentiation and basement membrane formation by HaCaT cells in surface transplants. Eur J Cell Biol (1998) 1.20

Organotypic cocultures with genetically modified mouse fibroblasts as a tool to dissect molecular mechanisms regulating keratinocyte growth and differentiation. J Invest Dermatol (2001) 1.19

Phenotypic and cytogenetic characteristics of different stages during spontaneous transformation of mouse keratinocytes in vitro. Carcinog Compr Surv (1985) 1.17

Autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte macrophage colony-stimulating factor in human gliomas with tumor progression. Am J Pathol (1999) 1.16

Differential modulation of epidermal keratinization in immortalized (HaCaT) and tumorigenic human skin keratinocytes (HaCaT-ras) by retinoic acid and extracellular Ca2+. Differentiation (1993) 1.14

Environmental induction of differentiation-specific keratins in malignant mouse keratinocyte lines. Eur J Cell Biol (1986) 1.14

Keratins of the human hair follicle: "hyperproliferative" keratins consistently expressed in outer root sheath cells in vivo and in vitro. Differentiation (1987) 1.12

Formation of epidermis after reimplantation of pure primary epidermal cell cultures from perinatal mouse skin. J Natl Cancer Inst (1974) 1.11

Tumor suppression in human skin carcinoma cells by chromosome 15 transfer or thrombospondin-1 overexpression through halted tumor vascularization. Proc Natl Acad Sci U S A (1999) 1.11

Expression and functional significance of vascular endothelial growth factor receptors in human tumor cells. Lab Invest (1999) 1.11

Normal keratinocytes suppress early stages of neoplastic progression in stratified epithelium. Cancer Res (1998) 1.06

Suppression in vivo of human papillomavirus type 18 E6-E7 gene expression in nontumorigenic HeLa X fibroblast hybrid cells. J Virol (1990) 1.01

Histomorphological and biochemical differentiation capacity in organotypic co-cultures of primary gingival cells. J Periodontal Res (1997) 1.00

Arachidonic acid and prostaglandin E2 release and enhanced cell proliferation induced by the phorbol ester TPA in a murine epidermal cell line. Cancer Lett (1981) 0.99

Epidermal morphogenesis and keratin expression in c-Ha-ras-transfected tumorigenic clones of the human HaCaT cell line. Cancer Res (1991) 0.97

Progressive stages of "transdifferentiation" from epidermal to mesenchymal phenotype induced by MyoD1 transfection, 5-aza-2'-deoxycytidine treatment, and selection for reduced cell attachment in the human keratinocyte line HaCaT. J Cell Biol (1992) 0.97

Mesenchyme-mediated and endogenous regulation of growth and differentiation of human skin keratinocytes derived from different body sites. Differentiation (1990) 0.96

Modifications of cell cycle controlling nuclear proteins by transforming growth factor beta in the HaCaT keratinocyte cell line. Oncogene (1992) 0.94

Expression of 5-lipoxygenase in differentiating human skin keratinocytes. Proc Natl Acad Sci U S A (1995) 0.94

TGF-beta isoforms are differentially expressed in increasing malignant grades of HaCaT keratinocytes, suggesting separate roles in skin carcinogenesis. J Pathol (2000) 0.94

Interleukin-1-induced growth factor expression in postmitotic and resting fibroblasts. J Invest Dermatol (1996) 0.93

Regeneration of organized epithelial structure. J Invest Dermatol (1983) 0.92

Growth and differentiation of postembryonic mouse epidermal cells in explant cultures. J Invest Dermatol (1979) 0.92

Mouse epidermal cell cultures. I. Isolation and cultivation of epidermal cells from adult mouse skin. J Invest Dermatol (1974) 0.92

Constitutive expression of G-CSF and GM-CSF in human skin carcinoma cells with functional consequence for tumor progression. Int J Cancer (1999) 0.91

Characteristics of chemically transformed mouse epidermal cells in vitro and in vivo. Bull Cancer (1978) 0.91

Tumorigenic conversion of immortal human skin keratinocytes (HaCaT) by elevated temperature. Oncogene (1999) 0.91

Sensitization of human keratinocytes to killing by parvovirus H-1 takes place during their malignant transformation but does not require them to be tumorigenic. Carcinogenesis (1989) 0.90

5-Lipoxygenase expression in Langerhans cells of normal human epidermis. Proc Natl Acad Sci U S A (1998) 0.90

Cell interactions control the fate of malignant keratinocytes in an organotypic model of early neoplasia. J Invest Dermatol (1999) 0.90

Differential stromal regulation of MMP-1 expression in benign and malignant keratinocytes. J Invest Dermatol (2001) 0.90

Step-wise progression in human skin carcinogenesis in vitro involves mutational inactivation of p53, rasH oncogene activation and additional chromosome loss. Oncogene (1995) 0.90

Plasminogen activator in differentiating mouse keratinocytes. J Invest Dermatol (1983) 0.90

Progressive abrogation of TGF-beta 1 and EGF growth control is associated with tumour progression in ras-transfected human keratinocytes. Int J Cancer (1992) 0.90

Angiogenic switch occurs late in squamous cell carcinomas of human skin. Br J Cancer (2000) 0.88

Migration of a human keratinocyte cell line (HACAT) to interstitial collagen type I is mediated by the alpha 2 beta 1-integrin receptor. J Invest Dermatol (1992) 0.88

12-O-tetradecanoylphorbol-13-acetate induces clonal expansion of potentially malignant keratinocytes in a tissue model of early neoplastic progression. Cancer Res (1999) 0.88

Expression and function of connexin in normal and transformed human keratinocytes in culture. Carcinogenesis (1994) 0.87

Establishment of oral mucosa phenotype in vitro in correlation to epithelial anchorage. Cell Tissue Res (1998) 0.87

DNA excision repair in ultraviolet-irradiated normal and malignantly transformed mouse epidermal cell cultures. Cancer Res (1977) 0.86

Binding of epidermal growth factor to primary and permanent cultures of mouse epidermal cells: inhibition by tumor-promoting phorbol esters. Cancer Lett (1979) 0.86

Tumor induction in initiated mouse skin by phorbol esters and methyl methanesulfonate: correlation between chromosomal damage and conversion ('stage I of tumor promotion') in vivo. Carcinogenesis (1989) 0.86

Expression and modification of keratins during terminal differentiation of mammalian epidermis. Curr Top Dev Biol (1987) 0.86

Correlation of prekaratin peptides and ultrastructure in epithelial cells of human skin tumors in vivo and in vitro. Anticancer Res (1981) 0.85

Inhibition of collagenase-3 (MMP-13) expression in transformed human keratinocytes by interferon-gamma is associated with activation of extracellular signal-regulated kinase-1,2 and STAT1. Oncogene (2000) 0.85

Functional evidence for tumor-suppressor activity on chromosome 15 in human skin carcinoma cells and thrombospondin-1 as the potential suppressor. J Cell Physiol (1997) 0.85

The amido black assay: a simple and quantitative multipurpose test of adhesion, proliferation, and cytotoxicity in microplate cultures of keratinocytes (HaCaT) and other cell types growing adherently or in suspension. J Immunol Methods (1994) 0.84

Reduction of diet-induced obesity by a combination of tea-catechin intake and regular swimming. Int J Obes (Lond) (2006) 0.84

Paracrine factor and cell-cell contact-mediated induction of protease and c-ets gene expression in malignant keratinocyte/dermal fibroblast cocultures. Exp Cell Res (1994) 0.84

A rapid procedure for flow cytometric DNA analysis in cultures of normal and transformed epidermal cells. J Invest Dermatol (1988) 0.83

Basement membrane formation by malignant mouse keratinocyte cell lines in organotypic culture and transplants: correlation with degree of morphologic differentiation. J Cancer Res Clin Oncol (1987) 0.83

Defects of basement membrane and hemidesmosome structure correlate with malignant phenotype and stromal interactions in HaCaT-Ras xenografts. Differentiation (1999) 0.83

Magnetic resonance imaging of nude mice with heterotransplanted high-grade squamous cell carcinomas: use of a low-loaded, covalently bound Gd-Hsa conjugate as contrast agent with high tumor affinity. Invest Radiol (2002) 0.83

Restoration of the epidermal phenotype by follicular outer root sheath cells in recombinant culture with dermal fibroblasts. Exp Cell Res (1991) 0.82

Organotypic and epidermal-dermal co-cultures of normal human keratinocytes and dermal cells: Regulation of transforming growth factor alpha, beta1 and beta2 mRNA levels. Toxicol In Vitro (1994) 0.82

Fibroblast-directed expression and localization of 92-kDa type IV collagenase along the tumor-stroma interface in an in vitro three-dimensional model of human squamous cell carcinoma. Mol Carcinog (1997) 0.82

Tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate enhances sister chromatid exchanges and numerical and structural chromosome aberrations in primary mouse epidermal cell cultures. Cancer Lett (1982) 0.82

[The effect of vincaleukoblastine (Velbe) on the glycolysis of tumor cells]. Eur J Cancer (1966) 0.82

Matrix metalloproteinases-2,-3,-7,-9 and-10, but not MMP-11, are differentially expressed in normal, benign tumorigenic and malignant human keratinocyte cell lines. Biol Chem (2000) 0.81

Isolation and cultivation of epidermal cells from embryonic mouse skin. Naturwissenschaften (1971) 0.81

Outer root sheath (ORS) cells organize into epidermoid cyst-like spheroids when cultured inside Matrigel: a light-microscopic and immunohistological comparison between human ORS cells and interfollicular keratinocytes. Cell Tissue Res (1994) 0.81

In vitro transformation and tumor progression. Recent Results Cancer Res (1993) 0.81

"Trans-differentiation" from epidermal to mesenchymal/myogenic phenotype is associated with a drastic change in cell-cell and cell-matrix adhesion molecules. J Cell Biol (1993) 0.80

5-lipoxygenase expression in cultured human keratinocytes. Adv Prostaglandin Thromboxane Leukot Res (1995) 0.80

Phenotypic modulation of human hair matrix cells (trichocytes) by environmental influence in vitro and in vivo. Epithelial Cell Biol (1993) 0.80

Experimental modulation of the differentiated phenotype of keratinocytes from epidermis and hair follicle outer root sheath and matrix cells. Ann N Y Acad Sci (1991) 0.79

Postreplication repair of DNA in ultraviolet light-irradiated normal and malignancy transformed mouse epidermal cell cultures. Cancer Res (1978) 0.79

Integrin and basement membrane normalization in mouse grafts of human keratinocytes--implications for epidermal homeostasis. Differentiation (1997) 0.79

Differential expression of matrix metalloproteinases in activated c-ras-Ha-transfected immortalized human keratinocytes. Br J Cancer (1998) 0.79

Association of deficient DNA repair during G2 phase with progression from benign to malignant state in a line of human skin keratinocytes transfected with ras oncogene. Carcinogenesis (1994) 0.79

Differentiation ability and oncogenic potential of HPV-33- and HPV-33 + ras-transfected keratinocytes. Int J Cancer (1994) 0.79