Published in Exp Cell Res on July 01, 1994
Contribution of matrilysin (MMP-7) to the metastatic pathway of human colorectal cancers. Gut (1999) 1.63
Expression of c-ets-1 mRNA is associated with an invasive, EMT-derived phenotype in breast carcinoma cell lines. Clin Exp Metastasis (1997) 1.03
Expression of c-ets-1, collagenase 1, and urokinase-type plasminogen activator genes in lung carcinomas. Am J Pathol (1995) 0.99
Regulation of matrilysin expression in cells of squamous cell carcinoma by E-cadherin-mediated cell-cell contact. J Cancer Res Clin Oncol (1997) 0.79
Differential expression of matrix metalloproteinases in activated c-ras-Ha-transfected immortalized human keratinocytes. Br J Cancer (1998) 0.79
Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol (1988) 16.82
Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas. Nature (1984) 4.28
Molecular and cytogenetic analysis of immortalized human primary keratinocytes obtained after transfection with human papillomavirus type 16 DNA. Oncogene (1987) 4.02
Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40. Science (2000) 3.20
Halting angiogenesis suppresses carcinoma cell invasion. Nat Med (1997) 2.61
Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization. Nat Med (1998) 2.54
c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin. Cell (2000) 2.35
The mRNA coding for the secreted protease transin is expressed more abundantly in malignant than in benign tumors. Proc Natl Acad Sci U S A (1986) 2.28
The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategies. J Cell Biol (2001) 1.94
Tumorigenic conversion of immortal human keratinocytes through stromal cell activation. Proc Natl Acad Sci U S A (1998) 1.82
Simultaneous expression of two different types of intermediate sized filaments in mouse keratinocytes proliferating in vitro. Differentiation (1979) 1.68
Epidermal growth factor. Ability of tumor promoter to alter its degradation, receptor affinity and receptor number. J Biol Chem (1980) 1.65
Mutual induction of growth factor gene expression by epidermal-dermal cell interaction. J Cell Biol (1993) 1.60
c-Ha-ras oncogene expression in immortalized human keratinocytes (HaCaT) alters growth potential in vivo but lacks correlation with malignancy. Cancer Res (1990) 1.59
Describing individual incidents of sexual abuse: a review of research on the effects of multiple sources of information on children's reports. Child Abuse Negl (2001) 1.55
Protein-antigen specific Ia-restricted cytolytic T cells: analysis of frequency, target cell susceptibility, and mechanism of cytolysis. J Immunol (1985) 1.53
Keratinocyte growth regulation in fibroblast cocultures via a double paracrine mechanism. J Cell Sci (1999) 1.52
Epidermal organization and differentiation of HaCaT keratinocytes in organotypic coculture with human dermal fibroblasts. J Invest Dermatol (1999) 1.51
Expression of collagenase-3 (MMP-13) and collagenase-1 (MMP-1) by transformed keratinocytes is dependent on the activity of p38 mitogen-activated protein kinase. J Cell Sci (2000) 1.50
Phenotypic and genotypic characteristics of a cell line from a squamous cell carcinoma of human skin. J Natl Cancer Inst (1982) 1.49
Multiple discrete encephalitogenic epitopes of the autoantigen myelin basic protein include a determinant for I-E class II-restricted T cells. J Exp Med (1988) 1.48
Reformation of organized epidermal structure by transplantation of suspensions and cultures of epidermal and dermal cells. Cell Tissue Res (1982) 1.45
Expression of the metalloproteinase matrilysin in DU-145 cells increases their invasive potential in severe combined immunodeficient mice. Cancer Res (1993) 1.45
Keratinocyte growth regulation in defined organotypic cultures through IL-1-induced keratinocyte growth factor expression in resting fibroblasts. J Invest Dermatol (2000) 1.43
Preservation of morphological, functional, and karyotypic traits during long-term culture and in vivo passage of two human skin squamous cell carcinomas. Cancer Res (1983) 1.42
Ultraviolet B regulation of transcription factor families: roles of nuclear factor-kappa B (NF-kappaB) and activator protein-1 (AP-1) in UVB-induced skin carcinogenesis. Curr Cancer Drug Targets (2007) 1.41
Environmental modulation of the expression of differentiation and malignancy in six human squamous cell carcinoma cell lines. Cancer Res (1985) 1.40
Epithelial-mesenchymal interactions control basement membrane production and differentiation in cultured and transplanted mouse keratinocytes. Cell Tissue Res (1986) 1.39
Differentiation specific functions in cultured and transplanted mouse keratinocytes: environmental influences on ultrastructure and keratin expression. Differentiation (1984) 1.39
Mouse epidermal cell cultures. II. Isolation, characterization and cultivation of epidermal cells from perinatal mouse skin. Exp Cell Res (1975) 1.39
Role of p38 MAP kinases and ERK in mediating ultraviolet-B induced cyclooxygenase-2 gene expression in human keratinocytes. Oncogene (2001) 1.36
Effect of growth environment on spatial expression of involucrin by human epidermal keratinocytes. Arch Dermatol Res (1987) 1.36
Growth and differentiation characteristics of transformed keratinocytes from mouse and human skin in vitro and in vivo. J Invest Dermatol (1983) 1.36
Different bile acids exhibit distinct biological effects: the tumor promoter deoxycholic acid induces apoptosis and the chemopreventive agent ursodeoxycholic acid inhibits cell proliferation. Nutr Cancer (1998) 1.34
Dynamics of basement membrane formation by keratinocyte-fibroblast interactions in organotypic skin culture. Exp Cell Res (1998) 1.33
Sustained nontumorigenic phenotype correlates with a largely stable chromosome content during long-term culture of the human keratinocyte line HaCaT. Genes Chromosomes Cancer (1997) 1.32
Organotypic keratinocyte cocultures in defined medium with regular epidermal morphogenesis and differentiation. J Invest Dermatol (1999) 1.32
Allele-specific methylation of the human c-Ha-ras-1 gene. Cell (1987) 1.31
Expression of metalloproteinase genes in human prostate cancer. J Cancer Res Clin Oncol (1991) 1.31
Increased ROS levels contribute to elevated transcription factor and MAP kinase activities in malignantly progressed mouse keratinocyte cell lines. Carcinogenesis (1999) 1.31
Density-dependent modulation of synthesis of keratins 1 and 10 in the human keratinocyte line HACAT and in ras-transfected tumorigenic clones. Differentiation (1989) 1.30
Proteolytic modification of acidic and basic keratins during terminal differentiation of mouse and human epidermis. Eur J Biochem (1984) 1.28
Comparison of two-stage epidermal carcinogenesis initiated by 7,12-dimethylbenz(a)anthracene or N-methyl-N'-nitro-N-nitrosoguanidine in newborn and adult SENCAR and BALB/c mice. Cancer Res (1981) 1.26
Expression pattern of a gene for a secreted metalloproteinase during late stages of tumor progression. Mol Carcinog (1988) 1.24
A set of cassette cloning vectors for rapid and versatile adaptation of restriction fragments. Biotechniques (1991) 1.21
Epidermal differentiation and basement membrane formation by HaCaT cells in surface transplants. Eur J Cell Biol (1998) 1.20
Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors. Proc Natl Acad Sci U S A (1992) 1.20
The differential inhibitory effect of lymphotoxin and immune interferon on normal and malignant lymphoid cells. Lymphokine Res (1985) 1.19
Organotypic cocultures with genetically modified mouse fibroblasts as a tool to dissect molecular mechanisms regulating keratinocyte growth and differentiation. J Invest Dermatol (2001) 1.19
Secreted phosphoprotein mRNA is induced during multi-stage carcinogenesis in mouse skin and correlates with the metastatic potential of murine fibroblasts. Int J Cancer (1990) 1.18
Phenotypic and cytogenetic characteristics of different stages during spontaneous transformation of mouse keratinocytes in vitro. Carcinog Compr Surv (1985) 1.17
Stromelysin/transin and tumor progression. Semin Cancer Biol (1990) 1.17
Autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte macrophage colony-stimulating factor in human gliomas with tumor progression. Am J Pathol (1999) 1.16
APC-dependent changes in expression of genes influencing polyamine metabolism, and consequences for gastrointestinal carcinogenesis, in the Min mouse. Carcinogenesis (1999) 1.15
Differential modulation of epidermal keratinization in immortalized (HaCaT) and tumorigenic human skin keratinocytes (HaCaT-ras) by retinoic acid and extracellular Ca2+. Differentiation (1993) 1.14
Environmental induction of differentiation-specific keratins in malignant mouse keratinocyte lines. Eur J Cell Biol (1986) 1.14
UVB irradiation-induced activator protein-1 activation correlates with increased c-fos gene expression in a human keratinocyte cell line. J Biol Chem (1998) 1.13
Keratins of the human hair follicle: "hyperproliferative" keratins consistently expressed in outer root sheath cells in vivo and in vitro. Differentiation (1987) 1.12
Adhesion molecules, extracellular matrix, and proteases in prostate carcinoma. J Cell Biochem Suppl (1994) 1.12
Stable expression of a c-JUN deletion mutant in two malignant mouse epidermal cell lines blocks tumor formation in nude mice. Cell Growth Differ (1994) 1.12
Tumor suppression in human skin carcinoma cells by chromosome 15 transfer or thrombospondin-1 overexpression through halted tumor vascularization. Proc Natl Acad Sci U S A (1999) 1.11
Formation of epidermis after reimplantation of pure primary epidermal cell cultures from perinatal mouse skin. J Natl Cancer Inst (1974) 1.11
Expression and functional significance of vascular endothelial growth factor receptors in human tumor cells. Lab Invest (1999) 1.11
Chemoprevention of human actinic keratoses by topical 2-(difluoromethyl)-dl-ornithine. Cancer Epidemiol Biomarkers Prev (2000) 1.09
Dose-response studies on the ability of 7,12-dimethylbenz(alpha)anthracene and benz(alpha)anthracene to initiate skin tumors. J Natl Cancer Inst (1974) 1.08
Inhibition of ultraviolet B-induced activator protein-1 (AP-1) activity by aspirin in AP-1-luciferase transgenic mice. J Biol Chem (1997) 1.08
Mitogen- and stress-activated protein kinase 1 mediates activation of Akt by ultraviolet B irradiation. J Biol Chem (2001) 1.08
Activation of p38 MAP kinase and ERK are required for ultraviolet-B induced c-fos gene expression in human keratinocytes. Oncogene (1999) 1.07
Comparison of ras activation during epidermal carcinogenesis in vitro and in vivo. Carcinogenesis (1991) 1.07
Normal keratinocytes suppress early stages of neoplastic progression in stratified epithelium. Cancer Res (1998) 1.06
Roles of Akt and glycogen synthase kinase 3beta in the ultraviolet B induction of cyclooxygenase-2 transcription in human keratinocytes. Cancer Res (2001) 1.05
Role of cyclic AMP responsive element in the UVB induction of cyclooxygenase-2 transcription in human keratinocytes. Oncogene (2001) 1.04
Cleavage of beta 4 integrin by matrilysin. Exp Cell Res (1997) 1.04
Ultraviolet B-induced activated protein-1 activation does not require epidermal growth factor receptor but is blocked by a dominant negative PKClambda/iota. J Biol Chem (1996) 1.03
p53 Phosphorylation: biochemical and functional consequences. Life Sci (1997) 1.03
Hyperpigmentation and melanocytic hyperplasia in transgenic mice expressing the human T24 Ha-ras gene regulated by a mouse tyrosinase promoter. Mol Carcinog (1995) 1.03
Effects of acute and subchronic exposure of topically applied fullerene extracts on the mouse skin. Toxicol Ind Health (1994) 1.03
Extracellular signal-regulated kinase 1/2-mediated phosphorylation of JunD and FosB is required for okadaic acid-induced activator protein 1 activation. J Biol Chem (1999) 1.02
Immunopathology of naturally occurring otodectic otoacariasis in the domestic cat. J Am Vet Med Assoc (1974) 1.02
A switch from stromal to tumor cell expression of stromelysin-1 mRNA associated with the conversion of squamous to spindle carcinomas during mouse skin tumor progression. Mol Carcinog (1994) 1.01
Attenuation of catalase activity in the malignant phenotype plays a functional role in an in vitro model for tumor progression. Cancer Lett (2001) 1.01
Suppression in vivo of human papillomavirus type 18 E6-E7 gene expression in nontumorigenic HeLa X fibroblast hybrid cells. J Virol (1990) 1.01
Histomorphological and biochemical differentiation capacity in organotypic co-cultures of primary gingival cells. J Periodontal Res (1997) 1.00
Arachidonic acid and prostaglandin E2 release and enhanced cell proliferation induced by the phorbol ester TPA in a murine epidermal cell line. Cancer Lett (1981) 0.99
Overexpression of three ubiquitin genes in mouse epidermal tumors is associated with enhanced cellular proliferation and stress. Cell Growth Differ (1992) 0.98
Epidermal morphogenesis and keratin expression in c-Ha-ras-transfected tumorigenic clones of the human HaCaT cell line. Cancer Res (1991) 0.97
Inhibitory effects of perillyl alcohol on UVB-induced murine skin cancer and AP-1 transactivation. Cancer Res (1998) 0.97
Mesenchyme-mediated and endogenous regulation of growth and differentiation of human skin keratinocytes derived from different body sites. Differentiation (1990) 0.96
Activation of gelatinase-tissue-inhibitors-of-metalloproteinase complexes by matrilysin. Biochem J (1998) 0.96
Inhibition of ultraviolet B--induced c-fos gene expression and p38 mitogen-activated protein kinase activation by (-)-epigallocatechin gallate in a human keratinocyte cell line. Mol Carcinog (1999) 0.96
Reaginic hypersensitivity in Otodectes cynotis infestation of cats and mode of mite feeding. Am J Vet Res (1980) 0.95
Synthetic peptides inhibit adhesion of human tumor cells to extracellular matrix proteins. Cancer Res (2001) 0.95
Induction of melanoma in TPras transgenic mice. Carcinogenesis (1999) 0.95
The relationship of interparental conflict and global marital adjustment to aggression, anxiety, and immaturity in aggressive and nonclinic children. J Abnorm Child Psychol (1991) 0.95
Lymphotoxin, a biologically relevant model lymphokine. Lymphokine Res (1983) 0.95
Modifications of cell cycle controlling nuclear proteins by transforming growth factor beta in the HaCaT keratinocyte cell line. Oncogene (1992) 0.94
Matrilysin expression in human prostate carcinoma. Mol Carcinog (1996) 0.94