PubRank

M V Norgard

Author PubWeight™ 149.52‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science 1999 8.63
2 Factors affecting the transformation of Escherichia coli strain chi1776 by pBR322 plasmid DNA. Gene 1978 5.15
3 Induction of direct antimicrobial activity through mammalian toll-like receptors. Science 2001 4.46
4 Immunogenic integral membrane proteins of Borrelia burgdorferi are lipoproteins. Infect Immun 1990 4.10
5 Expression of Borrelia burgdorferi OspC and DbpA is controlled by a RpoN-RpoS regulatory pathway. Proc Natl Acad Sci U S A 2001 3.65
6 Identification and localization of integral membrane proteins of virulent Treponema pallidum subsp. pallidum by phase partitioning with the nonionic detergent triton X-114. Infect Immun 1988 3.42
7 A new animal model for studying Lyme disease spirochetes in a mammalian host-adapted state. J Clin Invest 1998 3.41
8 Outer membrane ultrastructure explains the limited antigenicity of virulent Treponema pallidum. Proc Natl Acad Sci U S A 1989 3.17
9 Interdependence of environmental factors influencing reciprocal patterns of gene expression in virulent Borrelia burgdorferi. Mol Microbiol 2000 3.00
10 Evidence for in vivo but not in vitro expression of a Borrelia burgdorferi outer surface protein F (OspF) homologue. Mol Microbiol 1995 2.92
11 Increased amplification of pBR322 plasmid deoxyribonucleic acid in Escherichia coli K-12 strains RR1 and chi1776 grown in the presence of high concentrations of nucleoside. J Bacteriol 1979 2.55
12 Sensitive detection of Treponema pallidum by using the polymerase chain reaction. J Clin Microbiol 1991 2.51
13 Rapid and simple removal of contaminating RNA from plasmid DNA without the use of RNase. Anal Biochem 1981 2.51
14 Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2. J Immunol 2001 2.24
15 Decorin-binding protein of Borrelia burgdorferi is encoded within a two-gene operon and is protective in the murine model of Lyme borreliosis. Infect Immun 1998 2.23
16 Use of polymerase chain reaction and rabbit infectivity testing to detect Treponema pallidum in amniotic fluid, fetal and neonatal sera, and cerebrospinal fluid. J Clin Microbiol 1991 2.20
17 Identification, characterization, and expression of three new members of the Borrelia burgdorferi Mlp (2.9) lipoprotein gene family. Infect Immun 1999 2.18
18 Major integral membrane protein immunogens of Treponema pallidum are proteolipids. Infect Immun 1989 2.15
19 Borrelia burgdorferi supercoiled plasmids encode multicopy tandem open reading frames and a lipoprotein gene family. J Bacteriol 1996 2.14
20 Monoclonal antibody with hemagglutination, immobilization, and neutralization activities defines an immunodominant, 47,000 mol wt, surface-exposed immunogen of Treponema pallidum (Nichols). J Exp Med 1984 2.11
21 Lipoproteins of Borrelia burgdorferi and Treponema pallidum activate cachectin/tumor necrosis factor synthesis. Analysis using a CAT reporter construct. J Immunol 1991 2.09
22 Murine monoclonal antibodies specific for virulent Treponema pallidum (Nichols). Infect Immun 1982 2.08
23 Decorin-binding protein A (DbpA) of Borrelia burgdorferi is not protective when immunized mice are challenged via tick infestation and correlates with the lack of DbpA expression by B. burgdorferi in ticks. Infect Immun 2000 2.00
24 Cloning and expression of Treponema pallidum (Nichols) antigen genes in Escherichia coli. Infect Immun 1983 1.94
25 Limited surface exposure of Borrelia burgdorferi outer surface lipoproteins. Proc Natl Acad Sci U S A 1996 1.90
26 On the cloning of eukaryotic total poly(A)-RNA populations in Escherichia coli. J Biol Chem 1980 1.89
27 Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytes/macrophages. J Immunol 1995 1.86
28 Molecular and evolutionary analysis of Borrelia burgdorferi 297 circular plasmid-encoded lipoproteins with OspE- and OspF-like leader peptides. Infect Immun 1999 1.84
29 Monoclonal antibody analysis of specific antigenic similarities among pathogenic Treponema pallidum subspecies. Infect Immun 1984 1.77
30 Activation of toll-like receptor 2 on human dendritic cells triggers induction of IL-12, but not IL-10. J Immunol 2000 1.77
31 Plasmid DNA in Treponema pallidum (Nichols): potential for antibiotic resistance by syphilis bacteria. Science 1981 1.67
32 Characterization of outer membranes isolated from Borrelia burgdorferi, the Lyme disease spirochete. Infect Immun 1995 1.66
33 Analysis of Borrelia burgdorferi membrane architecture by freeze-fracture electron microscopy. J Bacteriol 1994 1.61
34 A hemoglobin-binding outer membrane protein is involved in virulence expression by Haemophilus ducreyi in an animal model. Infect Immun 1996 1.60
35 Evaluation of molecular methodologies and rabbit infectivity testing for the diagnosis of congenital syphilis and neonatal central nervous system invasion by Treponema pallidum. J Infect Dis 1993 1.60
36 Treponema pallidum TroA is a periplasmic zinc-binding protein with a helical backbone. Nat Struct Biol 1999 1.60
37 Molecular characterization of a 6.6-kilodalton Borrelia burgdorferi outer membrane-associated lipoprotein (lp6.6) which appears to be downregulated during mammalian infection. Infect Immun 1997 1.57
38 Treponema pallidum in gel microdroplets: a novel strategy for investigation of treponemal molecular architecture. Mol Microbiol 1995 1.54
39 Acylation of the 47-kilodalton major membrane immunogen of Treponema pallidum determines its hydrophobicity. Infect Immun 1989 1.53
40 Cloning and expression of the major 47-kilodalton surface immunogen of Treponema pallidum in Escherichia coli. Infect Immun 1986 1.50
41 Characterization of outer membranes isolated from Treponema pallidum, the syphilis spirochete. Infect Immun 1995 1.48
42 Fatty acids of Treponema pallidum and Borrelia burgdorferi lipoproteins. J Bacteriol 1994 1.48
43 Lipid modification of the 17-kilodalton membrane immunogen of Treponema pallidum determines macrophage activation as well as amphiphilicity. Infect Immun 1993 1.47
44 Monoclonal antibody selection and analysis of a recombinant DNA-derived surface immunogen of Treponema pallidum expressed in Escherichia coli. Infect Immun 1986 1.47
45 Localization of outer surface proteins A and B in both the outer membrane and intracellular compartments of Borrelia burgdorferi. J Bacteriol 1991 1.46
46 Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytic cells via a CD14-dependent pathway distinct from that used by lipopolysaccharide. J Immunol 1998 1.45
47 The 34-kilodalton membrane immunogen of Treponema pallidum is a lipoprotein. Infect Immun 1990 1.42
48 Molecular and evolutionary characterization of the cp32/18 family of supercoiled plasmids in Borrelia burgdorferi 297. Infect Immun 2000 1.38
49 Molecular characterization of the pathogen-specific, 34-kilodalton membrane immunogen of Treponema pallidum. Infect Immun 1989 1.37
50 Cloning and expression in Escherichia coli of the gene encoding the heat-modifiable major outer membrane protein of Haemophilus influenzae type b. Infect Immun 1987 1.37
51 Molecular cloning and DNA sequence analysis of the 37-kilodalton endoflagellar sheath protein gene of Treponema pallidum. Infect Immun 1989 1.37
52 Virulent Treponema pallidum activates human vascular endothelial cells. J Infect Dis 1992 1.33
53 Sequence analysis of the 47-kilodalton major integral membrane immunogen of Treponema pallidum. Infect Immun 1989 1.33
54 Pathogen specificity of Treponema pallidum subsp. pallidum integral membrane proteins identified by phase partitioning with Triton X-114. Infect Immun 1988 1.31
55 Cloning of the gene encoding the major outer membrane protein of Haemophilus influenzae type b. Infect Immun 1988 1.27
56 Genetic and physicochemical characterization of the recombinant DNA-derived 47-kilodalton surface immunogen of Treponema pallidum subsp. pallidum. Infect Immun 1988 1.26
57 Analysis of the N-terminal region of the 47-kilodalton integral membrane lipoprotein of Treponema pallidum. Infect Immun 1992 1.26
58 Membrane topology of Borrelia burgdorferi and Treponema pallidum lipoproteins. Infect Immun 1995 1.24
59 Influence of cultivation media on genetic regulatory patterns in Borrelia burgdorferi. Infect Immun 2001 1.20
60 Molecular analysis of the fetal IgM response to Treponema pallidum antigens: implications for improved serodiagnosis of congenital syphilis. J Infect Dis 1989 1.19
61 Virulent Treponema pallidum, lipoprotein, and synthetic lipopeptides induce CCR5 on human monocytes and enhance their susceptibility to infection by human immunodeficiency virus type 1. J Infect Dis 2000 1.13
62 Molecular specificities of monoclonal antibodies directed against virulent Treponema pallidum. Infect Immun 1986 1.13
63 Penicillin-binding proteins and peptidoglycan of Treponema pallidum subsp. pallidum. Infect Immun 1989 1.12
64 Identification of Treponema pallidum in amniotic fluid and fetal blood from pregnancies complicated by congenital syphilis. Obstet Gynecol 1991 1.06
65 The 47-kDa major lipoprotein immunogen of Treponema pallidum is a penicillin-binding protein with carboxypeptidase activity. Proc Natl Acad Sci U S A 1994 1.02
66 Digoxigenin-ampicillin conjugate for detection of penicillin-binding proteins by chemiluminescence. Antimicrob Agents Chemother 1994 1.01
67 Treponema pallidum rare outer membrane proteins: analysis of mobility by freeze-fracture electron microscopy. J Bacteriol 1994 0.99
68 Similarity between the 38-kilodalton lipoprotein of Treponema pallidum and the glucose/galactose-binding (MglB) protein of Escherichia coli. Infect Immun 1994 0.98
69 Physicochemical evidence that Treponema pallidum TroA is a zinc-containing metalloprotein that lacks porin-like structure. J Bacteriol 1999 0.96
70 Molecular cloning and characterization of the 15-kilodalton major immunogen of Treponema pallidum. Infect Immun 1989 0.96
71 Dendritic cells phagocytose and are activated by Treponema pallidum. Infect Immun 2001 0.94
72 Congenital syphilis associated with negative results of maternal serologic tests at delivery. Am J Dis Child 1991 0.92
73 Treponema pallidum, lipoproteins, and synthetic lipoprotein analogues induce human immunodeficiency virus type 1 gene expression in monocytes via NF-kappaB activation. J Infect Dis 1998 0.91
74 Monoclonal antibodies directed against major histocompatibility complex antigens bind to the surface of Treponema pallidum isolated from infected rabbits or humans. Cell Immunol 1986 0.90
75 A mgl-like operon in Treponema pallidum, the syphilis spirochete. Gene 1996 0.89
76 Sensitivity and specificity of monoclonal antibodies directed against antigenic determinants of Treponema pallidum Nichols in the diagnosis of syphilis. J Clin Microbiol 1984 0.88
77 Solid-phase synthesis of biologically active lipopeptides as analogs for spirochetal lipoproteins. Pept Res 1994 0.87
78 Evidence for a methyl-accepting chemotaxis protein gene (mcp1) that encodes a putative sensory transducer in virulent Treponema pallidum. Infect Immun 1997 0.86
79 Examination of amniotic fluid in diagnosing congenital syphilis with fetal death. Obstet Gynecol 1989 0.85
80 Virulent Treponema pallidum promotes adhesion of leukocytes to human vascular endothelial cells. Infect Immun 1994 0.85
81 Physiological factors involved in the transformation of Mycobacterium smegmatis. J Bacteriol 1978 0.83
82 Heterogeneity of deoxyribonucleic acid molecules isolated from Mycobacterium smegmatis. J Bacteriol 1980 0.82
83 IgM antibody to Treponema pallidum in cerebrospinal fluid of infants with congenital syphilis. Am J Dis Child 1992 0.81
84 Molecular assessment of S1 endonuclease-resistant snapback hairpin loops generated by DNA polymerase I during the in-vitro nick translation reaction. Appl Biochem Biotechnol 1985 0.78
85 A computer program for displaying two-dimensional gel electrophoresis data. Anal Biochem 1980 0.78
86 Phenotypic expression of the major 47 kDa surface immunogen of Treponema pallidum in virulent, tissue-cultured treponemes. J Gen Microbiol 1986 0.75