Published in Circ Res on August 06, 1999
Innovative Strategies For Risk Reduction Following CABG | NCT00462436
Prospective Study of Thoracolumbar Spinal Fusion Graft (BMAC) | NCT02297256
Intramyocardial Delivery of Autologous Bone Marrow | NCT00820586
Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization. Proc Natl Acad Sci U S A (2000) 6.59
Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines. J Clin Invest (2006) 4.51
Unchain my heart: the scientific foundations of cardiac repair. J Clin Invest (2005) 4.25
HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway. J Clin Invest (2001) 4.11
Administration of CD34+ cells after stroke enhances neurogenesis via angiogenesis in a mouse model. J Clin Invest (2004) 4.04
Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo. Nat Med (2001) 3.89
Clonally expanded novel multipotent stem cells from human bone marrow regenerate myocardium after myocardial infarction. J Clin Invest (2005) 3.61
Role of chemokines in tumor growth. Cancer Lett (2007) 3.36
Topical vascular endothelial growth factor accelerates diabetic wound healing through increased angiogenesis and by mobilizing and recruiting bone marrow-derived cells. Am J Pathol (2004) 3.13
Endothelial progenitor cells: identity defined? J Cell Mol Med (2009) 2.96
The role of prolactin in mammary carcinoma. Endocr Rev (2003) 2.95
Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells. Blood (2004) 2.95
Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer. Proc Natl Acad Sci U S A (2001) 2.81
Contribution of bone marrow-derived cells to skin: collagen deposition and wound repair. Stem Cells (2004) 2.70
In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion. J Clin Invest (2003) 2.63
Blood-derived angioblasts accelerate blood-flow restoration in diabetic mice. J Clin Invest (2000) 2.61
Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling. Proc Natl Acad Sci U S A (2010) 2.49
Glomeruloid microvascular proliferation follows adenoviral vascular permeability factor/vascular endothelial growth factor-164 gene delivery. Am J Pathol (2001) 2.38
Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow-derived cells. J Clin Invest (2003) 2.22
HMG-CoA reductase inhibitor mobilizes bone marrow--derived endothelial progenitor cells. J Clin Invest (2001) 2.20
Corneal angiogenic privilege: angiogenic and antiangiogenic factors in corneal avascularity, vasculogenesis, and wound healing (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc (2006) 2.12
Arteriogenesis versus angiogenesis: similarities and differences. J Cell Mol Med (2006) 2.05
Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction. Circ Res (2005) 2.04
Angiomyeloproliferative lesions following autologous stem cell therapy. J Am Soc Nephrol (2010) 2.04
Role of beta2-integrins for homing and neovascularization capacity of endothelial progenitor cells. J Exp Med (2004) 2.04
In vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrow. Diabetes (2004) 2.01
Ischemic vascular damage can be repaired by healthy, but not diabetic, endothelial progenitor cells. Diabetes (2007) 2.01
Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells. Mol Cell Biol (2001) 1.98
Exosome/microvesicle-mediated epigenetic reprogramming of cells. Am J Cancer Res (2010) 1.96
Human peripheral blood-derived CD31+ cells have robust angiogenic and vasculogenic properties and are effective for treating ischemic vascular disease. J Am Coll Cardiol (2010) 1.92
Genous endothelial progenitor cell capturing stent vs. the Taxus Liberte stent in patients with de novo coronary lesions with a high-risk of coronary restenosis: a randomized, single-centre, pilot study. Eur Heart J (2009) 1.90
Contribution of endothelial progenitors and proangiogenic hematopoietic cells to vascularization of tumor and ischemic tissue. Curr Opin Hematol (2006) 1.86
Origins of the tumor microenvironment: quantitative assessment of adipose-derived and bone marrow-derived stroma. PLoS One (2012) 1.82
Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis. J Clin Invest (2014) 1.82
Concise review: bone marrow-derived stem/progenitor cells in cutaneous repair and regeneration. Stem Cells (2010) 1.78
Tumour vascularization: sprouting angiogenesis and beyond. Cancer Metastasis Rev (2007) 1.76
Therapeutic potential of vasculogenesis and osteogenesis promoted by peripheral blood CD34-positive cells for functional bone healing. Am J Pathol (2006) 1.75
Chemokines as mediators of neovascularization. Arterioscler Thromb Vasc Biol (2008) 1.71
Endothelial progenitor cells in neovascularization of infarcted myocardium. J Mol Cell Cardiol (2008) 1.69
Hematopoietic myelomonocytic cells are the major source of hepatocyte fusion partners. J Clin Invest (2004) 1.67
Cell cycle regulator E2F1 modulates angiogenesis via p53-dependent transcriptional control of VEGF. Proc Natl Acad Sci U S A (2006) 1.66
G-CSF and AMD3100 mobilize monocytes into the blood that stimulate angiogenesis in vivo through a paracrine mechanism. Blood (2006) 1.66
Phase 1-2 study of docetaxel plus aflibercept in patients with recurrent ovarian, primary peritoneal, or fallopian tube cancer. Lancet Oncol (2011) 1.65
CXCR4 blockade augments bone marrow progenitor cell recruitment to the neovasculature and reduces mortality after myocardial infarction. Proc Natl Acad Sci U S A (2010) 1.61
Diabetes irreversibly depletes bone marrow-derived mesenchymal progenitor cell subpopulations. Diabetes (2014) 1.61
The great migration of bone marrow-derived stem cells toward the ischemic brain: therapeutic implications for stroke and other neurological disorders. Prog Neurobiol (2011) 1.61
Circulating endothelial cells and angiogenic serum factors during neoadjuvant chemotherapy of primary breast cancer. Br J Cancer (2006) 1.59
Multistep nature of microvascular recruitment of ex vivo-expanded embryonic endothelial progenitor cells during tumor angiogenesis. J Exp Med (2003) 1.58
Development of bioactive peptide amphiphiles for therapeutic cell delivery. Acta Biomater (2009) 1.57
CD133 positive endothelial progenitor cells contribute to the tumour vasculature in non-small cell lung cancer. J Clin Pathol (2004) 1.57
Invited review: activity-induced angiogenesis. Pflugers Arch (2008) 1.56
Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cells. J Exp Med (2005) 1.56
Circulating CD34+ progenitor cells and risk of mortality in a population with coronary artery disease. Circ Res (2014) 1.54
CXC-chemokine receptor 4 antagonist AMD3100 promotes cardiac functional recovery after ischemia/reperfusion injury via endothelial nitric oxide synthase-dependent mechanism. Circulation (2012) 1.53
Concise review: bone marrow mononuclear cells for the treatment of ischemic syndromes: medicinal product or cell transplantation? Stem Cells Transl Med (2012) 1.52
Diesel exhaust exposure induces angiogenesis. Toxicol Lett (2009) 1.48
Residential Proximity to Major Roadways Is Associated With Increased Levels of AC133+ Circulating Angiogenic Cells. Arterioscler Thromb Vasc Biol (2015) 1.48
Collagen matrix physical properties modulate endothelial colony forming cell-derived vessels in vivo. Microvasc Res (2010) 1.45
Mortality risk of darbepoetin alfa versus epoetin alfa in patients with CKD: systematic review and meta-analysis. Am J Kidney Dis (2015) 1.43
Heme-Mediated Induction of CXCL10 and Depletion of CD34+ Progenitor Cells Is Toll-Like Receptor 4 Dependent. PLoS One (2015) 1.43
Adenoviral transfer of HIF-1alpha enhances vascular responses to critical limb ischemia in diabetic mice. Proc Natl Acad Sci U S A (2009) 1.41
Circulating endothelial cells, endothelial progenitor cells, and endothelial microparticles in cancer. Neoplasia (2006) 1.41
Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity. Blood (2009) 1.40
Period2 deficiency blunts hypoxia-induced mobilization and function of endothelial progenitor cells. PLoS One (2014) 1.39
Endothelial progenitor cells for cardiovascular regeneration. Trends Cardiovasc Med (2008) 1.38
CD133+ renal progenitor cells contribute to tumor angiogenesis. Am J Pathol (2006) 1.36
The importance of the endothelium in atherothrombosis and coronary stenting. Nat Rev Cardiol (2012) 1.35
Circulating endothelial cells, microparticles and progenitors: key players towards the definition of vascular competence. J Cell Mol Med (2009) 1.35
Adenosine A(2A) receptor activation promotes wound neovascularization by stimulating angiogenesis and vasculogenesis. Am J Pathol (2004) 1.33
Role of endothelial progenitors and other bone marrow-derived cells in the development of the tumor vasculature. Angiogenesis (2009) 1.31
Bone marrow stem cell mobilization in stroke: a 'bonehead' may be good after all! Leukemia (2011) 1.31
Impairment in ischemia-induced neovascularization in diabetes: bone marrow mononuclear cell dysfunction and therapeutic potential of placenta growth factor treatment. Am J Pathol (2004) 1.31
Human fetal aorta contains vascular progenitor cells capable of inducing vasculogenesis, angiogenesis, and myogenesis in vitro and in a murine model of peripheral ischemia. Am J Pathol (2007) 1.31
Donor myocardial infarction impairs the therapeutic potential of bone marrow cells by an interleukin-1-mediated inflammatory response. Sci Transl Med (2011) 1.31
Myogenic stem cells for the therapy of primary myopathies: wishful thinking or therapeutic perspective? J Clin Invest (2000) 1.31
Pivotal role of the CCL5/CCR5 interaction for recruitment of endothelial progenitor cells in mouse wound healing. J Clin Invest (2012) 1.29
Endothelial progenitor cell biology in disease and tissue regeneration. J Hematol Oncol (2011) 1.29
Origin of neointimal endothelium and alpha-actin-positive smooth muscle cells in transplant arteriosclerosis. J Clin Invest (2001) 1.28
Stromal cell-derived factor-1alpha activation of tissue-engineered endothelial progenitor cell matrix enhances ventricular function after myocardial infarction by inducing neovasculogenesis. Circulation (2010) 1.28
The initial fetal human retinal vasculature develops by vasculogenesis. Dev Dyn (2006) 1.28
Bone-marrow-derived cells contribute to glomerular endothelial repair in experimental glomerulonephritis. Am J Pathol (2003) 1.28
Decreased circulating progenitor cell number and failed mechanisms of stromal cell-derived factor-1alpha mediated bone marrow mobilization impair diabetic tissue repair. Diabetes (2010) 1.28
CD36 in the periphery and brain synergizes in stroke injury in hyperlipidemia. Ann Neurol (2012) 1.27
Endothelial colony-forming cell role in neoangiogenesis and tissue repair. Curr Opin Organ Transplant (2010) 1.27
Allogeneic endometrial regenerative cells: an "Off the shelf solution" for critical limb ischemia? J Transl Med (2008) 1.27
Biomaterials approach to expand and direct differentiation of stem cells. Mol Ther (2007) 1.24
Vascular endothelial growth factor and substrate mechanics regulate in vitro tubulogenesis of endothelial progenitor cells. J Cell Mol Med (2010) 1.24
Dopamine regulates endothelial progenitor cell mobilization from mouse bone marrow in tumor vascularization. J Clin Invest (2008) 1.24
Effect of erythropoietin on level of circulating endothelial progenitor cells and outcome in patients after acute ischemic stroke. Crit Care (2011) 1.22
Breast tumour angiogenesis. Breast Cancer Res (2007) 1.22
IFATS collection: The role of human adipose-derived stromal cells in inflammatory microvascular remodeling and evidence of a perivascular phenotype. Stem Cells (2008) 1.22
Biologic properties of endothelial progenitor cells and their potential for cell therapy. Prog Cardiovasc Dis (2007) 1.22
Critical role of the nitric oxide/reactive oxygen species balance in endothelial progenitor dysfunction. Antioxid Redox Signal (2010) 1.22
S-nitrosoglutathione reductase (GSNOR) enhances vasculogenesis by mesenchymal stem cells. Proc Natl Acad Sci U S A (2013) 1.20
Combined delivery approach of bone marrow mononuclear stem cells early and late after myocardial infarction: the MYSTAR prospective, randomized study. Nat Clin Pract Cardiovasc Med (2008) 1.20
The neural stem/progenitor cell marker nestin is expressed in proliferative endothelial cells, but not in mature vasculature. J Histochem Cytochem (2010) 1.19
The role IL-1 in tumor-mediated angiogenesis. Front Physiol (2014) 1.19
Clinical and therapeutical implications of EPC biology in atherosclerosis. J Cell Mol Med (2006) 1.18
Retracted Circulating endothelial progenitor cells in cerebrovascular disease. J Clin Neurol (2008) 1.18
Isolation of putative progenitor endothelial cells for angiogenesis. Science (1997) 30.27
Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization. Nat Med (1999) 10.16
Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell (1993) 9.06
Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J Immunol (1999) 8.98
Ordered metal nanohole arrays made by a two-step replication of honeycomb structures of anodic alumina. Science (1995) 8.78
Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev (2001) 7.60
Expression of T-cell differentiation antigens on effector cells in cell-mediated cytotoxicity in vitro. Evidence for functional heterogeneity related to the surface phenotype of T cells. J Exp Med (1975) 7.20
A thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system. Pflugers Arch (1989) 6.98
Cell surface antigens of human malignant melanoma: mixed hemadsorption assays for humoral immunity to cultured autologous melanoma cells. Proc Natl Acad Sci U S A (1976) 6.82
VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO J (1999) 6.62
Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization. Proc Natl Acad Sci U S A (2000) 6.59
Patch clamp measurements on Xenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels. Pflugers Arch (1986) 6.15
Nitric oxide synthase modulates angiogenesis in response to tissue ischemia. J Clin Invest (1998) 5.95
ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis. EMBO Rep (2001) 5.32
Cardiomyocytes can be generated from marrow stromal cells in vitro. J Clin Invest (1999) 5.30
Surface alloantigens of plasma cells. J Exp Med (1970) 5.19
Cell surface antigens of human malignant melanoma. II. Serological typing with immune adherence assays and definition of two new surface antigens. J Exp Med (1976) 5.05
Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase. Nature (2000) 4.66
Molecular distinction between fetal and adult forms of muscle acetylcholine receptor. Nature (1986) 4.30
Mouse model of angiogenesis. Am J Pathol (1998) 4.28
Ore leaching by bacteria. Annu Rev Microbiol (1980) 4.28
Therapeutic potential of ex vivo expanded endothelial progenitor cells for myocardial ischemia. Circulation (2001) 4.17
Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia. Circulation (1998) 4.10
Serological analysis of cell surface antigens of malignant human brain tumors. Proc Natl Acad Sci U S A (1978) 3.99
The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors. Nat Med (2001) 3.85
Mortality of sea lions along the central California coast linked to a toxic diatom bloom. Nature (2000) 3.82
Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization. Circ Res (1998) 3.79
Loss of aquaporin 4 in lesions of neuromyelitis optica: distinction from multiple sclerosis. Brain (2007) 3.64
Immunoglobulin and other surface antigens of cells of the immune system. J Exp Med (1971) 3.50
Age-dependent impairment of angiogenesis. Circulation (1999) 3.47
Cell surface antigens of human renal cancer defined by autologous typing. J Exp Med (1979) 3.43
Cell surface antigens of human malignant melanoma. III. Recognition of autoantibodies with unusual characteristics. J Exp Med (1977) 3.42
Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas. Cancer Res (1998) 3.20
Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92. Oncogene (2007) 3.11
Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model. J Clin Invest (1994) 3.11
CBP as a transcriptional coactivator of c-Myb. Genes Dev (1996) 3.09
Numbers, time and neocortical neuronogenesis: a general developmental and evolutionary model. Trends Neurosci (1995) 3.08
Safe right subclavian vein puncture: the importance of pressing the skin with the left thumb. Am J Emerg Med (1993) 3.07
Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation. J Biol Chem (1999) 2.99
Mutations in the p53 gene are frequent in primary, resected non-small cell lung cancer. Lung Cancer Study Group. Oncogene (1990) 2.97
Expression of functional sodium channels from cloned cDNA. Nature (1986) 2.95
Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia. Circulation (1999) 2.92
Expression of the functional soluble form of human fas ligand in activated lymphocytes. EMBO J (1995) 2.87
Rescue of diabetes-related impairment of angiogenesis by intramuscular gene therapy with adeno-VEGF. Am J Pathol (1999) 2.83
Early-onset ataxia with ocular motor apraxia and hypoalbuminemia is caused by mutations in a new HIT superfamily gene. Nat Genet (2001) 2.79
Direct intramuscular gene transfer of naked DNA encoding vascular endothelial growth factor augments collateral development and tissue perfusion. Circulation (1996) 2.79
Observational contrains on the global atmospheric co2 budget. Science (1990) 2.76
Reciprocal relation between VEGF and NO in the regulation of endothelial integrity. Nat Med (1997) 2.73
Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti. Mol Cell (2000) 2.70
Developmental defects of lymphoid cells in Jak3 kinase-deficient mice. Immunity (1995) 2.70
Cellular hypertrophy and hyperplasia of airway smooth muscles underlying bronchial asthma. A 3-D morphometric study. Am Rev Respir Dis (1993) 2.69
Characterization of a cis-diamminedichloroplatinum(II)-resistant human ovarian cancer cell line and its use in evaluation of platinum analogues. Cancer Res (1987) 2.67
NF-kappa B RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses. J Exp Med (1997) 2.66
Distal myopathy with rimmed vacuoles is allelic to hereditary inclusion body myopathy. Neurology (2002) 2.66
Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice. Neuron (1996) 2.62
Detection of antibody to autologous human leukemia cells by immune adherence assays. Proc Natl Acad Sci U S A (1977) 2.59
Inactivation of presynaptic calcium current contributes to synaptic depression at a fast central synapse. Neuron (1998) 2.56
Molecular characterization of the stretch-induced adaptation of cultured cardiac cells. An in vitro model of load-induced cardiac hypertrophy. J Biol Chem (1992) 2.55
Microsatellite instability in acute myelocytic leukaemia developed from A-bomb survivors. Int J Radiat Biol (2001) 2.54
Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality. Proc Natl Acad Sci U S A (1999) 2.53
Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis. J Exp Med (1982) 2.52
Plasma fibronectin enhances phagocytosis of opsonized particles by human peripheral blood monocytes. J Exp Med (1983) 2.49
Expression of functional acetylcholine receptor from cloned cDNAs. Nature (1984) 2.41
Rat brain serotonin receptors in Xenopus oocytes are coupled by intracellular calcium to endogenous channels. Proc Natl Acad Sci U S A (1987) 2.41
Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer. Br J Cancer (2009) 2.39
Differences in sialic acid-galactose linkages in the chicken egg amnion and allantois influence human influenza virus receptor specificity and variant selection. J Virol (1997) 2.38
Restoration of TGF-beta signalling reduces tumorigenicity in human lung cancer cells. Br J Cancer (2005) 2.37
Non-NMDA glutamate receptor occupancy and open probability at a rat cerebellar synapse with single and multiple release sites. J Physiol (1996) 2.34
Secretion of a chromaffin granule protein, chromogranin, from the adrenal gland after splanchnic stimulation. Nature (1967) 2.29
Thiobacillus acidophilus sp. nov.; isolation and some physiological characteristics. Can J Microbiol (1975) 2.28
Vascular endothelial growth factor/vascular permeability factor enhances vascular permeability via nitric oxide and prostacyclin. Circulation (1998) 2.25
Astrocytic damage is far more severe than demyelination in NMO: a clinical CSF biomarker study. Neurology (2010) 2.24
Naturally anergic and suppressive CD25(+)CD4(+) T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation. Int Immunol (2000) 2.24