Published in Bone on November 01, 1999
Receptor activator of nuclear factor kappaB ligand and osteoprotegerin regulation of bone remodeling in health and disease. Endocr Rev (2007) 2.82
Osteocytes: master orchestrators of bone. Calcif Tissue Int (2013) 2.48
Osteoprotegerin inhibits vascular calcification without affecting atherosclerosis in ldlr(-/-) mice. Circulation (2008) 2.44
Osteoimmunology: interactions of the bone and immune system. Endocr Rev (2008) 2.32
Giant cell tumour of bone: morphological, biological and histogenetical aspects. Int Orthop (2006) 1.88
The osteocyte: an endocrine cell ... and more. Endocr Rev (2013) 1.84
Coupling the activities of bone formation and resorption: a multitude of signals within the basic multicellular unit. Bonekey Rep (2014) 1.57
Murine and chicken chondrocytes regulate osteoclastogenesis by producing RANKL in response to BMP2. J Bone Miner Res (2008) 1.53
Control of RANKL gene expression. Bone (2009) 1.47
Central control of fever and female body temperature by RANKL/RANK. Nature (2009) 1.42
Receptor activator of nuclear factor kappaB ligand (RANKL)/osteoprotegerin (OPG) ratio is increased in severe osteolysis. Am J Pathol (2003) 1.38
Osteoprotegerin reduces osteoclast numbers and prevents bone erosion in collagen-induced arthritis. Am J Pathol (2002) 1.38
Osteocyte control of osteoclastogenesis. Bone (2012) 1.36
Role of RANKL and RANK in bone loss and arthritis. Ann Rheum Dis (2002) 1.35
Biology of the RANKL-RANK-OPG System in Immunity, Bone, and Beyond. Front Immunol (2014) 1.29
Osteocyte RANKL: new insights into the control of bone remodeling. J Bone Miner Res (2012) 1.29
Molecular profiling of giant cell tumor of bone and the osteoclastic localization of ligand for receptor activator of nuclear factor kappaB. Am J Pathol (2005) 1.26
Detection of osteoprotegerin (OPG) and its ligand (RANKL) mRNA and protein in femur and tibia of the rat. J Mol Histol (2005) 1.25
Bone cell interactions through Eph/ephrin: bone modeling, remodeling and associated diseases. Cell Adh Migr (2012) 1.18
Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice. J Clin Invest (2010) 1.18
Receptor activator of NF-kappaB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit. Proc Natl Acad Sci U S A (2011) 1.13
Commitment to the osteoblast lineage is not required for RANKL gene expression. J Biol Chem (2009) 1.05
C-type natriuretic peptide regulates endochondral bone growth through p38 MAP kinase-dependent and -independent pathways. BMC Dev Biol (2007) 1.03
Usefulness of a quick decalcification of bone sections embedded in methyl methacrylate[corrected]: an improved method for immunohistochemistry. J Bone Miner Metab (2008) 1.01
Bisphosphonates regulate cell growth and gene expression in the UMR 106-01 clonal rat osteosarcoma cell line. Br J Cancer (2001) 1.00
A comprehensive manually curated reaction map of RANKL/RANK-signaling pathway. Database (Oxford) (2011) 0.99
Targeting RANKL in metastasis. Bonekey Rep (2014) 0.95
Osteocyte apoptosis is required for production of osteoclastogenic signals following bone fatigue in vivo. Bone (2014) 0.94
Involvement of integrins alpha(3)beta(1) and alpha(5)beta(1) and glycoprotein IIb in megakaryocyte-induced osteoblast proliferation. J Cell Biochem (2010) 0.93
Osteocyte-derived RANKL is a critical mediator of the increased bone resorption caused by dietary calcium deficiency. Bone (2014) 0.92
Bone vascularization in normal and disease conditions. Front Endocrinol (Lausanne) (2013) 0.91
OPG/RANKL/RANK axis is a critical inflammatory signaling system in ischemic brain in mice. Proc Natl Acad Sci U S A (2014) 0.89
The tumor necrosis factor superfamily of cytokines in the inflammatory myopathies: potential targets for therapy. Clin Dev Immunol (2011) 0.88
Giant cell tumour of bone: new treatments in development. Clin Transl Oncol (2015) 0.87
Immunohistological identification of receptor activator of NF-kappaB ligand (RANKL) in human, ovine and bovine bone tissues. J Mater Sci Mater Med (2004) 0.87
Regulation of neurite growth by tumour necrosis superfamily member RANKL. Open Biol (2013) 0.86
Circulating RANKL is inversely related to RANKL mRNA levels in bone in osteoarthritic males. Arthritis Res Ther (2008) 0.84
RANKL is a mediator of bone resorption in idiopathic hypercalciuria. Clin J Am Soc Nephrol (2008) 0.83
RANK (TNFRSF11A) is epigenetically inactivated and induces apoptosis in gliomas. Neoplasia (2012) 0.83
Blood biomarkers of osteoporosis in mild cognitive impairment and Alzheimer's disease. J Neural Transm (Vienna) (2009) 0.82
Receptor activator of NF-kappaB and podocytes: towards a function of a novel receptor-ligand pair in the survival response of podocyte injury. PLoS One (2012) 0.82
Estrogens antagonize RUNX2-mediated osteoblast-driven osteoclastogenesis through regulating RANKL membrane association. Bone (2015) 0.81
Chondrocytes-Specific Expression of Osteoprotegerin Modulates Osteoclast Formation in Metaphyseal Bone. Sci Rep (2015) 0.81
RANKL cytokine: from pioneer of the osteoimmunology era to cure for a rare disease. Clin Dev Immunol (2013) 0.80
Is RANKL inhibition both anti-resorptive and anabolic in rheumatoid arthritis? Arthritis Res Ther (2015) 0.79
Effects of the administration of corticosterone, parathyroid hormone, or both, and of their withdrawal, on rat bone and cartilage histomorphometric parameters, and on osteoprotegerin and RANKL mRNA expression and proteins. J Mol Histol (2007) 0.78
TNFα signaling regulates cystic epithelial cell proliferation through Akt/mTOR and ERK/MAPK/Cdk2 mediated Id2 signaling. PLoS One (2015) 0.78
Impact of hepatitis C virus infection on bone mineral density in renal transplant recipients. PLoS One (2013) 0.78
Regulation of vacuolar H(+)-ATPase in microglia by RANKL. Biochem Biophys Res Commun (2009) 0.78
Tartrate-resistant acid phosphatase (TRAP) co-localizes with receptor activator of NF-KB ligand (RANKL) and osteoprotegerin (OPG) in lysosomal-associated membrane protein 1 (LAMP1)-positive vesicles in rat osteoblasts and osteocytes. Histochem Cell Biol (2014) 0.78
Paradoxical response to mechanical unloading in bone loss, microarchitecture, and bone turnover markers. Int J Med Sci (2015) 0.78
Immunoregulation of bone remodelling. Int J Crit Illn Inj Sci (2012) 0.77
Importance of antiresorptive therapies for patients with bone metastases from solid tumors. Cancer Manag Res (2012) 0.76
Age-related effects on osteoclastic activities after orthodontic tooth movement. Bone Joint Res (2016) 0.75
Amlodipine and atorvastatin improved hypertensive cardiac hypertrophy through regulation of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin system in spontaneous hypertension rats. Exp Biol Med (Maywood) (2016) 0.75
Rhabdomyolysis-induced acute kidney injury in a cancer patient exposed to denosumab and abiraterone: a case report. BMC Nephrol (2015) 0.75
RANK-RANKL signalling in cancer. Biosci Rep (2016) 0.75
The Modulatory Effects of Mesenchymal Stem Cells on Osteoclastogenesis. Stem Cells Int (2015) 0.75
Acceleration of osteoblast differentiation by a novel osteogenic compound, DMP-PYT, through activation of both the BMP and Wnt pathways. Sci Rep (2017) 0.75
Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr Rev (1999) 7.69
IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest (1999) 7.66
Essential role for oncogenic Ras in tumour maintenance. Nature (1999) 6.51
Quantitative profiling of differentiation-induced microsomal proteins using isotope-coded affinity tags and mass spectrometry. Nat Biotechnol (2001) 5.69
Therapeutic approaches to bone diseases. Science (2000) 5.60
Angiopoietin-1 protects the adult vasculature against plasma leakage. Nat Med (2000) 5.58
A tool for analyzing and annotating genomic sequences. Genomics (1997) 5.33
Accuracy of body mass index in diagnosing obesity in the adult general population. Int J Obes (Lond) (2008) 5.03
Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction. J Exp Med (2000) 5.02
The phosphatidylinositol 3'-kinase p85alpha gene is an oncogene in human ovarian and colon tumors. Cancer Res (2001) 4.63
Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells. Proc Natl Acad Sci U S A (1990) 4.40
Osteoblastic cells are involved in osteoclast formation. Endocrinology (1988) 4.37
Modulation of osteoclast differentiation. Endocr Rev (1992) 4.27
Association between maternal serum concentration of the DDT metabolite DDE and preterm and small-for-gestational-age babies at birth. Lancet (2001) 4.19
Induction of a dominant negative CREB transgene specifically blocks long-term memory in Drosophila. Cell (1994) 4.15
Role of osteoblasts in hormonal control of bone resorption--a hypothesis. Calcif Tissue Int (1981) 3.77
Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation. Nature (1997) 3.74
Increased vascularization in mice overexpressing angiopoietin-1. Science (1998) 3.67
A case-management system for coronary risk factor modification after acute myocardial infarction. Ann Intern Med (1994) 3.61
Exosomes from human saliva as a source of microRNA biomarkers. Oral Dis (2009) 3.11
A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines. Oncogene (1997) 3.08
CREB as a memory modulator: induced expression of a dCREB2 activator isoform enhances long-term memory in Drosophila. Cell (1995) 3.00
A novel orthotopic model of breast cancer metastasis to bone. Clin Exp Metastasis (1999) 2.93
The bone marrow-derived stromal cell lines MC3T3-G2/PA6 and ST2 support osteoclast-like cell differentiation in cocultures with mouse spleen cells. Endocrinology (1989) 2.83
Onset and rate of striatal atrophy in preclinical Huntington disease. Neurology (2004) 2.81
Interim report and recommendations of the World Health Organization Task-Force for Osteoporosis. Osteoporos Int (1999) 2.70
Effects of daily treatment with parathyroid hormone on bone microarchitecture and turnover in patients with osteoporosis: a paired biopsy study. J Bone Miner Res (2001) 2.65
Longitudinal studies of Aedes aegypti (Diptera: Culicidae) in Thailand and Puerto Rico: population dynamics. J Med Entomol (2000) 2.58
Incidence and time course of thromboembolic outcomes following total hip or knee arthroplasty. Arch Intern Med (1998) 2.58
Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons. Proc Natl Acad Sci U S A (1999) 2.41
Involvement of receptor activator of NFkappaB ligand and tumor necrosis factor-alpha in bone destruction in rheumatoid arthritis. Bone (2002) 2.40
The hypercalcemia of cancer. Clinical implications and pathogenic mechanisms. N Engl J Med (1984) 2.33
Malignant glaucoma after laser iridotomy. Ophthalmology (1992) 2.28
Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide. Mol Cell Biol (1998) 2.28
Activated T lymphocytes support osteoclast formation in vitro. Biochem Biophys Res Commun (1999) 2.28
The beneficial effect of delayed compressive loading on tissue-engineered cartilage constructs cultured with TGF-beta3. Osteoarthritis Cartilage (2007) 2.26
Continued breast cancer risk reduction in postmenopausal women treated with raloxifene: 4-year results from the MORE trial. Multiple outcomes of raloxifene evaluation. Breast Cancer Res Treat (2001) 2.26
Localization of parathyroid hormone-related protein in breast cancer metastases: increased incidence in bone compared with other sites. Cancer Res (1991) 2.26
Major bleeding after hospitalization for deep-venous thrombosis. Am J Med (1999) 2.25
Seven novel methylation guide small nucleolar RNAs are processed from a common polycistronic transcript by Rat1p and RNase III in yeast. Mol Cell Biol (1999) 2.20
The use of Medpor coated tear drainage tube in conjunctivodacryocystorhinostomy. Eye (Lond) (2007) 2.13
Genetic ablation of parathyroid glands reveals another source of parathyroid hormone. Nature (2000) 2.13
A suppressor of TBP mutations encodes an RNA polymerase III transcription factor with homology to TFIIB. Cell (1992) 2.12
Breast cancer cells interact with osteoblasts to support osteoclast formation. Endocrinology (1999) 2.11
Neonatal maternal separation alters stress-induced responses to viscerosomatic nociceptive stimuli in rat. Am J Physiol Gastrointest Liver Physiol (2002) 2.10
Transcriptional activation by Gcn4p involves independent interactions with the SWI/SNF complex and the SRB/mediator. Mol Cell (1999) 2.09
Context sequences of translation initiation codon in plants. Plant Mol Biol (1997) 2.05
Maturation and maintenance of the neuromuscular synapse: genetic evidence for roles of the dystrophin--glycoprotein complex. Neuron (2000) 2.04
Chronic severe hemolytic anemia related to surreptitious phenazopyridine abuse. Ann Intern Med (1994) 2.03
Influence of Nitrate and Ammonia on Photosynthetic Characteristics and Leaf Anatomy of Moricandia arvensis. Plant Physiol (1982) 2.02
The hypercalcemia of malignancy: pathogenesis and management. Metabolism (1982) 2.01
Substrate specificity and energetics of antiseptic and disinfectant resistance in Staphylococcus aureus. FEMS Microbiol Lett (1992) 1.99
Catabolic effects of continuous human PTH (1--38) in vivo is associated with sustained stimulation of RANKL and inhibition of osteoprotegerin and gene-associated bone formation. Endocrinology (2001) 1.98
Recombinant respiratory syncytial viruses with deletions in the NS1, NS2, SH, and M2-2 genes are attenuated in vitro and in vivo. Virology (2000) 1.98
The human osteoclast precursor circulates in the monocyte fraction. Endocrinology (1996) 1.89
A conserved cytoplasmic region of ROMK modulates pH sensitivity, conductance, and gating. Am J Physiol (1997) 1.88
Mechanical properties and cell cultural response of polycaprolactone scaffolds designed and fabricated via fused deposition modeling. J Biomed Mater Res (2001) 1.87
Are myogenin and myoD1 expression specific for rhabdomyosarcoma? A study of 150 cases, with emphasis on spindle cell mimics. Am J Surg Pathol (2001) 1.86
Incidence of idiopathic deep venous thrombosis and secondary thromboembolism among ethnic groups in California. Ann Intern Med (1998) 1.86
Angiopoietins 3 and 4: diverging gene counterparts in mice and humans. Proc Natl Acad Sci U S A (1999) 1.84
Simvastatin improves sepsis-induced mortality and acute kidney injury via renal vascular effects. Kidney Int (2006) 1.83
Nosocomial pneumonia caused by carbapenem-resistant Raoultella planticola: a case report and literature review. Infection (2015) 1.82
Her4 mediates ligand-dependent antiproliferative and differentiation responses in human breast cancer cells. Mol Cell Biol (2001) 1.80
Parathyroid hormone-related protein in hypercalcaemia associated with haematological malignancy. Br J Haematol (1996) 1.79
Prevalence of human respiratory viruses in adults with acute respiratory tract infections in Beijing, 2005-2007. Clin Microbiol Infect (2009) 1.76
RYR1 mutations are a common cause of congenital myopathies with central nuclei. Ann Neurol (2010) 1.75
Osteotropic agents regulate the expression of osteoclast differentiation factor and osteoprotegerin in osteoblastic stromal cells. Endocrinology (1998) 1.75
Functional domains of transcription factor TFIIB. Proc Natl Acad Sci U S A (1993) 1.75
A combination of osteoclast differentiation factor and macrophage-colony stimulating factor is sufficient for both human and mouse osteoclast formation in vitro. Endocrinology (1998) 1.75
Intercommunity differences in acid aerosol (H+)/sulfate (SO4(2-) ratios. J Expo Anal Environ Epidemiol (1996) 1.74
Apoptosis and regeneration of hepatocytes during recovery from transient hepadnavirus infections. J Virol (2000) 1.73
Abundant calcitonin receptors in isolated rat osteoclasts. Biochemical and autoradiographic characterization. J Clin Invest (1986) 1.73
Molecular analysis of a gentamicin resistance transposonlike element on plasmids isolated from North American Staphylococcus aureus strains. Antimicrob Agents Chemother (1990) 1.71
Effects of parathyroid hormone on Wnt signaling pathway in bone. J Cell Biochem (2005) 1.71
Epidemiology of alveolar echinococcosis with particular reference to China and Europe. Parasitology (2003) 1.69
Age- and gender-specific rate of fractures in Australia: a population-based study. Osteoporos Int (1999) 1.69
Downregulation of transcription factor SOX2 in cancer stem cells suppresses growth and metastasis of lung cancer. Br J Cancer (2011) 1.69
Insulin receptor expression in primary and cultured osteoclast-like cells. Bone (1998) 1.68
Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle. J Biol Chem (2001) 1.68
Clinical trials on CIK cells: first report of the international registry on CIK cells (IRCC). J Cancer Res Clin Oncol (2010) 1.67
Radiological factors influencing femoral and acetabular failure in cemented Charnley total hip arthroplasties. J Bone Joint Surg Br (1999) 1.67
High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha1-antitrypsin with negligible toxicity. Hum Gene Ther (1998) 1.67
Bone morphogenetic protein 2 stimulates osteoclast differentiation and survival supported by receptor activator of nuclear factor-kappaB ligand. Endocrinology (2001) 1.66
The exclusion of high trauma fractures may underestimate the prevalence of bone fragility fractures in the community: the Geelong Osteoporosis Study. J Bone Miner Res (1998) 1.65