Published in Semin Cell Dev Biol on October 01, 1999
Exploring the conditional coregulation of yeast gene expression through fuzzy k-means clustering. Genome Biol (2002) 4.24
Protein quality control in the early secretory pathway. EMBO J (2008) 3.59
Control of sleep and wakefulness. Physiol Rev (2012) 3.06
Ablation of the UPR-mediator CHOP restores motor function and reduces demyelination in Charcot-Marie-Tooth 1B mice. Neuron (2008) 2.95
CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism. J Neurochem (2005) 2.08
A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1. J Cell Biol (2004) 2.07
Small-molecule hydrophobic tagging-induced degradation of HaloTag fusion proteins. Nat Chem Biol (2011) 1.98
Endoplasmic reticulum protein quality control and its relationship to environmental stress responses in plants. Plant Cell (2010) 1.96
Caloric restriction and intermittent fasting: two potential diets for successful brain aging. Ageing Res Rev (2006) 1.94
Neuroendocrine secretory protein 7B2: structure, expression and functions. Biochem J (2001) 1.85
A review of the mammalian unfolded protein response. Biotechnol Bioeng (2011) 1.83
Sequential assistance of molecular chaperones and transient formation of covalent complexes during protein degradation from the ER. J Cell Biol (2002) 1.68
Association of elevated GRP78 expression with increased lymph node metastasis and poor prognosis in patients with gastric cancer. Clin Exp Metastasis (2006) 1.64
Stable binding of ATF6 to BiP in the endoplasmic reticulum stress response. Mol Cell Biol (2005) 1.64
Nucleotide exchange factor for the yeast Hsp70 molecular chaperone Ssa1p. Mol Cell Biol (2002) 1.62
GRP78, a coreceptor for coxsackievirus A9, interacts with major histocompatibility complex class I molecules which mediate virus internalization. J Virol (2002) 1.58
Oxidative protein folding in the endoplasmic reticulum: tight links to the mitochondria-associated membrane (MAM). Biochim Biophys Acta (2010) 1.50
Subtilase cytotoxin activates PERK, IRE1 and ATF6 endoplasmic reticulum stress-signalling pathways. Cell Microbiol (2008) 1.49
ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C. Mol Biol Cell (2008) 1.44
Essential roles of receptor-interacting protein and TRAF2 in oxidative stress-induced cell death. Mol Cell Biol (2004) 1.43
Identification of proteins associating with glycosylphosphatidylinositol- anchored T-cadherin on the surface of vascular endothelial cells: role for Grp78/BiP in T-cadherin-dependent cell survival. Mol Cell Biol (2008) 1.42
Golgi-mediated vacuolar sorting of the endoplasmic reticulum chaperone BiP may play an active role in quality control within the secretory pathway. Plant Cell (2005) 1.36
Endoplasmic reticulum stress activates the expression of a sub-group of protein disulfide isomerase genes and AtbZIP60 modulates the response in Arabidopsis thaliana. Mol Genet Genomics (2008) 1.36
Influence of KDEL on the fate of trimeric or assembly-defective phaseolin: selective use of an alternative route to vacuoles. Plant Cell (2001) 1.34
Involvement of ER stress in retinal cell death. Mol Vis (2007) 1.32
A new role for BiP: closing the aqueous translocon pore during protein integration into the ER membrane. J Cell Biol (2002) 1.30
Cellular stress/the unfolded protein response: relevance to sleep and sleep disorders. Sleep Med Rev (2009) 1.27
Expression profiling on soybean leaves reveals integration of ER- and osmotic-stress pathways. BMC Genomics (2007) 1.17
Target gene search for the metal-responsive transcription factor MTF-1. Nucleic Acids Res (2001) 1.16
Alteration of the unfolded protein response modifies neurodegeneration in a mouse model of Marinesco-Sjögren syndrome. Hum Mol Genet (2010) 1.13
In vivo interrogation of the molecular display of atherosclerotic lesion surfaces. Am J Pathol (2003) 1.13
Sls1p stimulates Sec63p-mediated activation of Kar2p in a conformation-dependent manner in the yeast endoplasmic reticulum. Mol Cell Biol (2000) 1.13
Curcumin treatment abrogates endoplasmic reticulum retention and aggregation-induced apoptosis associated with neuropathy-causing myelin protein zero-truncating mutants. Am J Hum Genet (2005) 1.11
Resolution-associated molecular patterns (RAMP): RAMParts defending immunological homeostasis? Clin Exp Immunol (2011) 1.10
Characterisation of Arabidopsis calnexin 1 and calnexin 2 in the endoplasmic reticulum and at plasmodesmata. Protoplasma (2015) 1.09
The structural and functional diversity of Hsp70 proteins from Plasmodium falciparum. Protein Sci (2007) 1.09
Major SNP (Q141K) variant of human ABC transporter ABCG2 undergoes lysosomal and proteasomal degradations. Pharm Res (2008) 1.09
Ero1alpha requires oxidizing and normoxic conditions to localize to the mitochondria-associated membrane (MAM). Cell Stress Chaperones (2010) 1.07
Immunolocalization of UDP-glucose:glycoprotein glucosyltransferase indicates involvement of pre-Golgi intermediates in protein quality control. Proc Natl Acad Sci U S A (2001) 1.06
Both thermal and non-thermal stress protect against caerulein induced pancreatitis and prevent trypsinogen activation in the pancreas. Gut (2002) 1.05
Renal response to metabolic acidosis: role of mRNA stabilization. Kidney Int (2007) 1.02
Endoplasmic reticulum chaperones stabilize nicotinic receptor subunits and regulate receptor assembly. J Biol Chem (2007) 1.01
p16INK4a-induced senescence is disabled by melanoma-associated mutations. Aging Cell (2008) 1.01
Protein carbonylation in a murine model for early alcoholic liver disease. Chem Res Toxicol (2012) 1.00
A murine model of autosomal dominant neurohypophyseal diabetes insipidus reveals progressive loss of vasopressin-producing neurons. J Clin Invest (2003) 1.00
Binding immunoglobulin protein-treated peripheral blood monocyte-derived dendritic cells are refractory to maturation and induce regulatory T-cell development. Immunology (2009) 0.99
Hsp70 and antifibrillogenic peptides promote degradation and inhibit intracellular aggregation of amyloidogenic light chains. J Cell Biol (2001) 0.97
Unfolded protein response-regulated Drosophila Fic (dFic) protein reversibly AMPylates BiP chaperone during endoplasmic reticulum homeostasis. J Biol Chem (2014) 0.96
Calnexin overexpression increases manganese peroxidase production in Aspergillus niger. Appl Environ Microbiol (2002) 0.96
Escherichia coli Subtilase Cytotoxin. Toxins (Basel) (2010) 0.96
Intrinsically disordered regions of p53 family are highly diversified in evolution. Biochim Biophys Acta (2013) 0.96
BiP availability distinguishes states of homeostasis and stress in the endoplasmic reticulum of living cells. Mol Biol Cell (2010) 0.95
Endoplasmic reticulum quality control regulates the fate of transthyretin variants in the cell. EMBO J (2007) 0.95
Role of endoplasmic reticulum stress in atherosclerosis and diabetic macrovascular complications. Biomed Res Int (2014) 0.94
An inducer of VGF protects cells against ER stress-induced cell death and prolongs survival in the mutant SOD1 animal models of familial ALS. PLoS One (2010) 0.94
The synovial proteome: analysis of fibroblast-like synoviocytes. Arthritis Res Ther (2004) 0.94
Uncoating ATPase Hsc70 is recruited by invariant chain and controls the size of endocytic compartments. Proc Natl Acad Sci U S A (2002) 0.94
Mouse RIC-3, an endoplasmic reticulum chaperone, promotes assembly of the alpha7 acetylcholine receptor through a cytoplasmic coiled-coil domain. J Neurosci (2009) 0.94
Subtilase cytotoxin cleaves newly synthesized BiP and blocks antibody secretion in B lymphocytes. J Exp Med (2009) 0.94
Escherichia coli subtilase cytotoxin induces apoptosis regulated by host Bcl-2 family proteins Bax/Bak. Infect Immun (2010) 0.93
Subcellular localization and rearrangement of endoplasmic reticulum by Brome mosaic virus capsid protein. J Virol (2011) 0.93
The binding protein BiP attenuates stress-induced cell death in soybean via modulation of the N-rich protein-mediated signaling pathway. Plant Physiol (2011) 0.93
A phaseolin domain involved directly in trimer assembly is a determinant for binding by the chaperone BiP. Plant Cell (2003) 0.93
Down-regulation of GRP78 is associated with the sensitivity of chemotherapy to VP-16 in small cell lung cancer NCI-H446 cells. BMC Cancer (2008) 0.92
The secreted plant N-glycoproteome and associated secretory pathways. Front Plant Sci (2012) 0.92
Chaperones and foldases in endoplasmic reticulum stress signaling in plants. Plant Signal Behav (2011) 0.89
Hyperoxia augments ER-stress-induced cell death independent of BiP loss. Free Radic Biol Med (2009) 0.88
Purification and biochemical characterization of native ERp29 from rat liver. Biochem J (2004) 0.88
Mechanisms of lipase maturation. Clin Lipidol (2010) 0.88
Review: Modulating the unfolded protein response to prevent neurodegeneration and enhance memory. Neuropathol Appl Neurobiol (2015) 0.88
Absence of BiP co-chaperone DNAJC3 causes diabetes mellitus and multisystemic neurodegeneration. Am J Hum Genet (2014) 0.87
Unfolded protein stress in the endoplasmic reticulum and mitochondria: a role in neurodegeneration. Front Aging Neurosci (2012) 0.87
The SANT2 domain of the murine tumor cell DnaJ-like protein 1 human homologue interacts with alpha1-antichymotrypsin and kinetically interferes with its serpin inhibitory activity. J Biol Chem (2003) 0.87
GRP78 promoter polymorphism rs391957 as potential predictor for clinical outcome in gastric and colorectal cancer patients. Ann Oncol (2011) 0.87
Dealing with misfolded proteins: examining the neuroprotective role of molecular chaperones in neurodegeneration. Molecules (2010) 0.86
Misregulation of PPAR Functioning and Its Pathogenic Consequences Associated with Nonalcoholic Fatty Liver Disease in Human Obesity. PPAR Res (2012) 0.86
ERdj3 regulates BiP occupancy in living cells. J Cell Sci (2013) 0.85
Contribution of the HEDJ/ERdj3 cysteine-rich domain to substrate interactions. Arch Biochem Biophys (2007) 0.85
Identification of p58IPK as a novel neuroprotective factor for retinal neurons. Invest Ophthalmol Vis Sci (2015) 0.85
Cell death signalling mechanisms in heart failure. Exp Clin Cardiol (2011) 0.85
N-rich protein (NRP)-mediated cell death signaling: a new branch of the ER stress response with implications for plant biotechnology. Plant Signal Behav (2012) 0.84
Inhibition of protein synthesis by TOR inactivation revealed a conserved regulatory mechanism of the BiP chaperone in Chlamydomonas. Plant Physiol (2011) 0.84
IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation. Nat Cell Biol (2015) 0.84
The immunosuppressive and protective ability of glucose-regulated protein 78 for improvement of alloimmunity in beta cell transplantation. Clin Exp Immunol (2007) 0.84
Endoplasmic reticulum stress in human skeletal muscle: any contribution to sarcopenia? Front Physiol (2013) 0.83
The altered expression of glucose-regulated proteins 78 in different phase of streptozotocin-affected pancreatic beta-cells. Cell Stress Chaperones (2008) 0.83
Role of p58IPK in Endoplasmic Reticulum Stress-associated Apoptosis and Inflammation. J Ophthalmic Vis Res (2014) 0.83
A New-Age for Biologic Therapies: Long-Term Drug-Free Therapy with BiP? Front Immunol (2012) 0.83
Inducible hsp70 in the regulation of cancer cell survival: analysis of chaperone induction, expression and activity. Cancers (Basel) (2011) 0.83
Activation profiles of HSPA5 during the glomerular mesangial cell stress response to chemical injury. Cell Stress Chaperones (2007) 0.82
Molecular mechanisms in multiple myeloma drug resistance. J Clin Pathol (2015) 0.82
Myelin-associated glycoprotein gene mutation causes Pelizaeus-Merzbacher disease-like disorder. Brain (2015) 0.82
Curcumin facilitates a transitory cellular stress response in Trembler-J mice. Hum Mol Genet (2013) 0.80
ATF6 [corrected] and thrombospondin 4: the dynamic duo of the adaptive endoplasmic reticulum stress response. Circ Res (2013) 0.80
Acute ER stress regulates amyloid precursor protein processing through ubiquitin-dependent degradation. Sci Rep (2015) 0.80
The B7-1 cytoplasmic tail enhances intracellular transport and mammalian cell surface display of chimeric proteins in the absence of a linear ER export motif. PLoS One (2013) 0.79
Gene expression in primary cultured astrocytes affected by aluminum: alteration of chaperons involved in protein folding. Environ Health Prev Med (2010) 0.79
Prevention of Doxorubicin cardiopathic changes by a benzyl styryl sulfone in mice. Genes Cancer (2011) 0.79
The degree of folding instability of the envelope protein of a neurovirulent murine retrovirus correlates with the severity of the neurological disease. J Virol (2009) 0.79
Heavy chain deposition disease: an overview. Clin Exp Nephrol (2013) 0.79
Binding sites for Hsp70 molecular chaperones in natural proteins. Cold Spring Harb Symp Quant Biol (1995) 0.90
Molecular chaperones: clasping the prize. Curr Biol (1996) 0.77