Published in Dev Biol on January 01, 2000
Repressor activity of Headless/Tcf3 is essential for vertebrate head formation. Nature (2000) 2.49
Secreted and transmembrane wnt inhibitors and activators. Cold Spring Harb Perspect Biol (2013) 2.01
Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins. Mol Cell Biol (2002) 1.60
Canonical Wnt signaling dynamically controls multiple stem cell fate decisions during vertebrate body formation. Dev Cell (2012) 1.43
Generation and characterization of dickkopf3 mutant mice. Mol Cell Biol (2006) 1.26
The CCN family member Wisp3, mutant in progressive pseudorheumatoid dysplasia, modulates BMP and Wnt signaling. J Clin Invest (2007) 1.19
Building the posterior lateral line system in zebrafish. Dev Neurobiol (2012) 1.18
Combinatorial Fgf and Bmp signalling patterns the gastrula ectoderm into prospective neural and epidermal domains. Development (2004) 1.17
Evolutionary conservation of early mesoderm specification by mechanotransduction in Bilateria. Nat Commun (2013) 1.06
Zebrafish Naked1 and Naked2 antagonize both canonical and non-canonical Wnt signaling. Dev Biol (2007) 1.05
Tfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population. Dev Biol (2011) 1.01
Integration of BMP and Wnt signaling via vertebrate Smad1/5/8 and Drosophila Mad. Cytokine Growth Factor Rev (2009) 1.00
Antagonistic role of vega1 and bozozok/dharma homeobox genes in organizer formation. Proc Natl Acad Sci U S A (2000) 1.00
Completion of the epithelial to mesenchymal transition in zebrafish mesoderm requires Spadetail. Dev Biol (2011) 1.00
Regulated tissue fluidity steers zebrafish body elongation. Development (2013) 0.96
Wnt signaling is regulated by endoplasmic reticulum retention. PLoS One (2009) 0.95
Dopaminergic neuronal cluster size is determined during early forebrain patterning. Development (2008) 0.91
Evolution of axis specification mechanisms in jawed vertebrates: insights from a chondrichthyan. PLoS One (2007) 0.90
Wnt signaling induces differentiation of progenitor cells in organotypic keratinocyte cultures. BMC Dev Biol (2007) 0.90
Crosstalk between Fgf and Wnt signaling in the zebrafish tailbud. Dev Biol (2012) 0.90
Nkd1 functions as a passive antagonist of Wnt signaling. PLoS One (2013) 0.89
Full transcriptome analysis of early dorsoventral patterning in zebrafish. PLoS One (2013) 0.85
Dkk1, -2, and -3 expression in mouse craniofacial development. J Mol Histol (2005) 0.84
Fezf2 regulates telencephalic precursor differentiation from mouse embryonic stem cells. Cereb Cortex (2011) 0.84
Endogenous WNT signaling regulates hPSC-derived neural progenitor cell heterogeneity and specifies their regional identity. Stem Cell Reports (2014) 0.83
Silver nanoparticles induce developmental stage-specific embryonic phenotypes in zebrafish. Nanoscale (2013) 0.81
R-spondin 3 regulates dorsoventral and anteroposterior patterning by antagonizing Wnt/β-catenin signaling in zebrafish embryos. PLoS One (2014) 0.78
Wnt signaling during tooth replacement in zebrafish (Danio rerio): pitfalls and perspectives. Front Physiol (2014) 0.77
The Nogo-C2/Nogo receptor complex regulates the morphogenesis of zebrafish lateral line primordium through modulating the expression of dkk1b, a Wnt signal inhibitor. PLoS One (2014) 0.76
Endocytic Adaptor Protein Tollip Inhibits Canonical Wnt Signaling. PLoS One (2015) 0.75
Ottogi Inhibits Wnt/β-catenin Signaling by Regulating Cell Membrane Trafficking of Frizzled8. Sci Rep (2017) 0.75
Derivation of telencephalic oligodendrocyte progenitors from human pluripotent stem cells. Curr Protoc Stem Cell Biol (2017) 0.75
The transcriptional landscape of the mammalian genome. Science (2005) 37.63
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol (1995) 29.42
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature (2002) 28.79
Functional annotation of a full-length mouse cDNA collection. Nature (2001) 23.61
JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell (1994) 16.30
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun (1999) 14.25
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med (2002) 14.15
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int Immunol (1998) 11.26
Occludin: a novel integral membrane protein localizing at tight junctions. J Cell Biol (1993) 10.65
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol (2000) 9.85
Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin. Nature (1986) 9.63
Multifunctional strands in tight junctions. Nat Rev Mol Cell Biol (2001) 9.62
A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family. EMBO J (1990) 9.17
Engineered GFP as a vital reporter in plants. Curr Biol (1996) 9.03
Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev (2001) 7.60
A genetic screen for mutations affecting embryogenesis in zebrafish. Development (1996) 7.12
Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation (2000) 6.96
Delineating developmental and metabolic pathways in vivo by expression profiling using the RIKEN set of 18,816 full-length enriched mouse cDNA arrays. Proc Natl Acad Sci U S A (2001) 6.07
Identification of Xenopus SMC protein complexes required for sister chromatid cohesion. Genes Dev (1998) 5.78
Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130. Cell (1989) 5.72
Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas. Nature (1988) 5.60
Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors. Oncogene (2000) 5.39
Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway. Circulation (2000) 5.36
Biology of multifunctional cytokines: IL 6 and related molecules (IL 1 and TNF). FASEB J (1990) 5.16
A 300 kilobase interval genetic map of rice including 883 expressed sequences. Nat Genet (1994) 5.08
Molecular cloning and expression of an IL-6 signal transducer, gp130. Cell (1990) 5.06
Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. J Cell Biol (1994) 5.01
Thermostabilization and thermoactivation of thermolabile enzymes by trehalose and its application for the synthesis of full length cDNA. Proc Natl Acad Sci U S A (1998) 4.95
Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor. Science (1988) 4.93
Spatio-temporal images of growth-factor-induced activation of Ras and Rap1. Nature (2001) 4.83
Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation (2001) 4.82
Clinical Studies on Behçet's Syndrome. Ann Rheum Dis (1963) 4.61
High-efficiency full-length cDNA cloning by biotinylated CAP trapper. Genomics (1996) 4.41
JNK is involved in signal integration during costimulation of T lymphocytes. Cell (1994) 4.36
Endovascular stent-graft placement for the treatment of acute aortic dissection. N Engl J Med (1999) 4.33
The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells. J Exp Med (1988) 4.31
A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis. Nature (1997) 4.27
Abdominal fat: standardized technique for measurement at CT. Radiology (1999) 4.25
IgG1 plasmacytosis in interleukin 6 transgenic mice. Proc Natl Acad Sci U S A (1989) 4.03
ATP-dependent positive supercoiling of DNA by 13S condensin: a biochemical implication for chromosome condensation. Cell (1997) 3.95
Phosphorylation and activation of 13S condensin by Cdc2 in vitro. Science (1998) 3.89
Infection with HIV is associated with elevated IL-6 levels and production. J Immunol (1990) 3.89
Behçet disease (Behçet syndrome). Semin Arthritis Rheum (1979) 3.88
Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib. J Bone Miner Res (2000) 3.86
CD36 deficiency associated with insulin resistance. Lancet (2001) 3.82
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Genome Res (2000) 3.78
Molecular regulation of B lymphocyte response. Annu Rev Immunol (1988) 3.68
Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis. Immunity (1996) 3.66
Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene. EMBO J (1987) 3.64
Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development (1996) 3.63
Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions. J Cell Biol (1998) 3.62
Studies on protein binding of cefazolin and other antibiotics. Jpn J Antibiot (1974) 3.59
Chromospheric alfvenic waves strong enough to power the solar wind. Science (2007) 3.58
c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions. Cell (1996) 3.54
Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2). Proc Natl Acad Sci U S A (1985) 3.46
A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells. EMBO J (1996) 3.40
IFNβ-1b may severely exacerbate Japanese optic-spinal MS in neuromyelitis optica spectrum. Neurology (2010) 3.34
Molecular structure of human lymphocyte receptor for immunoglobulin E. Cell (1986) 3.34
Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family. Proc Natl Acad Sci U S A (1991) 3.31
Interleukins and IgA synthesis. Human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cells. J Exp Med (1989) 3.28
Cell-to-cell adherens junction formation and actin filament organization: similarities and differences between non-polarized fibroblasts and polarized epithelial cells. J Cell Sci (1995) 3.27
IL-6 signal transduction and its physiological roles: the signal orchestration model. Rev Physiol Biochem Pharmacol (2003) 3.26
13S condensin actively reconfigures DNA by introducing global positive writhe: implications for chromosome condensation. Cell (1999) 3.24
MHC class II molecules are not required for survival of newly generated CD4+ T cells, but affect their long-term life span. Immunity (1996) 3.20
IL-6 is produced by osteoblasts and induces bone resorption. J Immunol (1990) 3.14
IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase. Science (1993) 3.13
Neurological response to early removal of ovarian teratoma in anti-NMDAR encephalitis. J Neurol Neurosurg Psychiatry (2007) 3.12
Chemical nature of the light emitter of the Aequorea green fluorescent protein. Proc Natl Acad Sci U S A (1996) 3.12
Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function. Development (1998) 3.07
Serum IgG antibody to ganglioside GQ1b is a possible marker of Miller Fisher syndrome. Ann Neurol (1992) 3.04
Molecular cloning and characterization of a surface antigen preferentially overexpressed on multiple myeloma cells. Biochem Biophys Res Commun (1999) 3.03
Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity. Nat Med (1996) 3.02
Bacterial lipopolysaccharide and inflammatory mediators augment IL-6 secretion by human endothelial cells. J Immunol (1989) 3.01
Occludin as a possible determinant of tight junction permeability in endothelial cells. J Cell Sci (1997) 2.97
Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. J Cell Biol (1996) 2.94
Analysis of upstream elements in the HuC promoter leads to the establishment of transgenic zebrafish with fluorescent neurons. Dev Biol (2000) 2.93
Identification and characterization of SA/Scc3p subunits in the Xenopus and human cohesin complexes. J Cell Biol (2000) 2.91
Role of cytosolic phospholipase A2 in allergic response and parturition. Nature (1997) 2.88
Non-invasive quantitative detection and applications of non-toxic, S65T-type green fluorescent protein in living plants. Plant J (1999) 2.88
B cell stimulating factor 2/interleukin 6 is a costimulant for human thymocytes and T lymphocytes. J Exp Med (1988) 2.88
Submembranous junctional plaque proteins include potential tumor suppressor molecules. J Cell Biol (1993) 2.87
Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival. Gastroenterology (1993) 2.86
Afadin: A novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junction. J Cell Biol (1997) 2.82
Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rch1. EMBO J (1997) 2.80
AIDS Kaposi sarcoma-derived cells produce and respond to interleukin 6. Proc Natl Acad Sci U S A (1990) 2.79
Indoleamine 2,3-dioxygenase. Purification and some properties. J Biol Chem (1978) 2.78
Human B-cell differentiation factor defined by an anti-peptide antibody and its possible role in autoantibody production. Proc Natl Acad Sci U S A (1987) 2.76
Mycobacterial and other serious infections in patients receiving anti-tumor necrosis factor and other newly approved biologic therapies: case finding through the Emerging Infections Network. Clin Infect Dis (2008) 2.69
Acute lung injury by sepsis and acid aspiration: a key role for cytosolic phospholipase A2. Nat Immunol (2000) 2.67
HEAT repeats associated with condensins, cohesins, and other complexes involved in chromosome-related functions. Genome Res (2000) 2.66
Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth. Genomics (1995) 2.65
The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension. Dev Cell (2001) 2.64
Transmission of bacteriocinogenicity by conjugation in group D streptococci. Jpn J Microbiol (1973) 2.60