Published in Front Physiol on October 06, 2014
The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol (2004) 24.63
Wnt/β-catenin signaling and disease. Cell (2012) 16.05
Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol Cell Biol (2002) 10.95
beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell (2001) 8.41
Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature (1998) 8.02
Secreted antagonists of the Wnt signalling pathway. J Cell Sci (2003) 8.02
WNT signals are required for the initiation of hair follicle development. Dev Cell (2002) 6.63
The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation. Cell (1997) 6.10
Function and biological roles of the Dickkopf family of Wnt modulators. Oncogene (2006) 5.12
Distinct Wnt signaling pathways have opposing roles in appendage regeneration. Development (2006) 4.88
GSK3 inhibitors: development and therapeutic potential. Nat Rev Drug Discov (2004) 3.93
Balancing cell adhesion and Wnt signaling, the key role of beta-catenin. Curr Opin Genet Dev (2005) 3.79
WNT and DKK determine hair follicle spacing through a reaction-diffusion mechanism. Science (2006) 3.36
Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer. Am J Hum Genet (2004) 3.21
Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin. EMBO Rep (2001) 3.02
The Wnt/beta-catenin pathway regulates cardiac valve formation. Nature (2003) 2.89
ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function. Genes Dev (1997) 2.78
DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway. Oncogene (2004) 2.73
Dickkopf genes are co-ordinately expressed in mesodermal lineages. Mech Dev (1999) 2.36
Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis. Dev Biol (2007) 2.26
Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A (2006) 2.25
Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling. Mol Cell Biol (2003) 2.03
GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis. Cell (1998) 2.03
A mutation in the Gsk3-binding domain of zebrafish Masterblind/Axin1 leads to a fate transformation of telencephalon and eyes to diencephalon. Genes Dev (2001) 1.90
Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development. Dev Biol (2009) 1.73
Ectopic Wnt signal determines the eyeless phenotype of zebrafish masterblind mutant. Development (2001) 1.67
Tooth shape formation and tooth renewal: evolving with the same signals. Development (2012) 1.64
Apc inhibition of Wnt signaling regulates supernumerary tooth formation during embryogenesis and throughout adulthood. Development (2009) 1.59
Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning. Development (2010) 1.43
From individual Wnt pathways towards a Wnt signalling network. Philos Trans R Soc Lond B Biol Sci (2008) 1.37
Fgf signaling is required for zebrafish tooth development. Dev Biol (2004) 1.33
The ventral and posterior expression of the zebrafish homeobox gene eve1 is perturbed in dorsalized and mutant embryos. Development (1993) 1.33
Adenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia. EMBO Rep (2006) 1.33
Molecular genetics of supernumerary tooth formation. Genesis (2011) 1.32
Zebrafish Dkk1 functions in forebrain specification and axial mesendoderm formation. Dev Biol (2000) 1.21
Deconstructing the ßcatenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signaling. Mol Biol Cell (2011) 1.21
Tinkering with the inductive mesenchyme: Sostdc1 uncovers the role of dental mesenchyme in limiting tooth induction. Development (2009) 1.18
nemo-like kinase is an essential co-activator of Wnt signaling during early zebrafish development. Development (2004) 1.18
Dynamics of tooth formation and replacement in the zebrafish (Danio rerio) (Teleostei, Cyprinidae). Dev Dyn (2000) 1.16
The WNT signaling pathway from ligand secretion to gene transcription: molecular mechanisms and pharmacological targets. Pharmacol Ther (2013) 1.14
Lef1 is required for progenitor cell identity in the zebrafish lateral line primordium. Development (2011) 1.13
Common developmental pathways link tooth shape to regeneration. Dev Biol (2013) 1.10
Expression of Dlx genes during the development of the zebrafish pharyngeal dentition: evolutionary implications. Evol Dev (2006) 1.10
Reptilian tooth development. Genesis (2011) 1.08
Identification of putative dental epithelial stem cells in a lizard with life-long tooth replacement. Development (2010) 1.08
A network of Wnt, hedgehog and BMP signaling pathways regulates tooth replacement in snakes. Dev Biol (2010) 1.07
Looking beyond the Wnt pathway for the deep nature of β-catenin. EMBO Rep (2013) 1.06
Molecular patterning of the mammalian dentition. Semin Cell Dev Biol (2013) 1.05
Continuous tooth replacement: the possible involvement of epithelial stem cells. Bioessays (2004) 1.01
Regulation of Wnt/β-catenin signaling by posttranslational modifications. Cell Biosci (2014) 1.00
Dynamic expression of Wnt signaling-related Dickkopf1, -2, and -3 mRNAs in the developing mouse tooth. Dev Dyn (2005) 0.99
Evolution of patterns and processes in teeth and tooth-related tissues in non-mammalian vertebrates. Eur J Oral Sci (1998) 0.99
Evolution and developmental diversity of tooth regeneration. Semin Cell Dev Biol (2014) 0.98
Secreted frizzled-related proteins are required for Wnt/β-catenin signalling activation in the vertebrate optic cup. Development (2011) 0.96
Formation of a successional dental lamina in the zebrafish (Danio rerio): support for a local control of replacement tooth initiation. Int J Dev Biol (2006) 0.96
Specialized stem cell niche enables repetitive renewal of alligator teeth. Proc Natl Acad Sci U S A (2013) 0.95
Intra-epithelial requirement of canonical Wnt signaling for tooth morphogenesis. J Biol Chem (2013) 0.94
The structural basis of DKK-mediated inhibition of Wnt/LRP signaling. Sci Signal (2012) 0.94
Wnt/Dkk negative feedback regulates sensory organ size in zebrafish. Curr Biol (2013) 0.91
Inhibition of Wnt signaling by exogenous Mfrzb1 protein affects molar tooth size. J Dent Res (2000) 0.89
Organized emergence of multiple-generations of teeth in snakes is dysregulated by activation of Wnt/beta-catenin signalling. PLoS One (2013) 0.88
Frat is dispensable for canonical Wnt signaling in mammals. Genes Dev (2005) 0.87
Wnt signalling underlies the evolution of new phenotypes and craniofacial variability in Lake Malawi cichlids. Nat Commun (2014) 0.86
Fgf signaling controls pharyngeal taste bud formation through miR-200 and Delta-Notch activity. Development (2011) 0.86
Whole mount immunohistochemistry and in situ hybridization of larval and adult zebrafish dental tissues. Methods Mol Biol (2012) 0.85
New insights into the regulation of Axin function in canonical Wnt signaling pathway. Protein Cell (2014) 0.85
Development of cartilage and bone tissues of the anterior part of the mandible in cichlid fish: a light and TEM study. Anat Rec (1992) 0.85
The dental phenotype in familial adenomatous polyposis: diagnostic application of a weighted scoring system for changes on dental panoramic radiographs. J Med Genet (1995) 0.84
A quantitative analysis of pharyngeal tooth shape in the zebrafish (Danio rerio, Teleostei, Cyprinidae). Arch Oral Biol (2001) 0.83
Manipulation of Fgf and Bmp signaling in teleost fishes suggests potential pathways for the evolutionary origin of multicuspid teeth. Evol Dev (2014) 0.81
Distinct expression patterns of dickkopf genes during late embryonic development of Danio rerio. Gene Expr Patterns (2011) 0.81
Targeting the Wnt pathway in zebrafish as a screening method to identify novel therapeutic compounds. Exp Biol Med (Maywood) (2014) 0.80
Wnt signaling in the murine diastema. Eur J Orthod (2011) 0.80
Tooth development in vitro in two teleost fish, the cichlid Hemichromis bimaculatus and the cyprinid Danio rerio. Cell Tissue Res (2005) 0.78
Inhibition of caudal fin regeneration in Corydoras aeneus by lithium chloride. Micron (2013) 0.76
Molecular characterization of dental development in a toothed archosaur, the American alligator Alligator mississippiensis. Evol Dev (2013) 0.76