Published in Regul Pept on January 29, 2000
A genetically clamped renin transgene for the induction of hypertension. Proc Natl Acad Sci U S A (2002) 1.15
Antibiotic resistance mutations in 16S and 23S ribosomal RNA genes of Escherichia coli. Nucleic Acids Res (1984) 3.94
Antibiotic resistance mutations in ribosomal RNA genes of Escherichia coli. Methods Enzymol (1988) 3.60
Nonsense codons in human beta-globin mRNA result in the production of mRNA degradation products. Mol Cell Biol (1992) 2.51
Differential expression of angiotensin receptor 1A and 1B in mouse. Am J Physiol (1994) 1.91
RAS blockade decreases blood pressure and proteinuria in transgenic mice overexpressing rat angiotensinogen gene in the kidney. Kidney Int (2006) 1.88
The kidney androgen-regulated protein promoter confers renal proximal tubule cell-specific and highly androgen-responsive expression on the human angiotensinogen gene in transgenic mice. J Biol Chem (1997) 1.78
Erythromycin resistance due to a mutation in a ribosomal RNA operon of Escherichia coli. Proc Natl Acad Sci U S A (1982) 1.73
The brain renin-angiotensin system contributes to the hypertension in mice containing both the human renin and human angiotensinogen transgenes. Circ Res (1998) 1.73
Critical roles of a cyclic AMP responsive element and an E-box in regulation of mouse renin gene expression. J Biol Chem (2001) 1.72
Novel mechanism of hypertension revealed by cell-specific targeting of human angiotensinogen in transgenic mice. Physiol Genomics (1999) 1.60
Divergent functions of angiotensin II receptor isoforms in the brain. J Clin Invest (2000) 1.59
Chronic hypertension and altered baroreflex responses in transgenic mice containing the human renin and human angiotensinogen genes. J Clin Invest (1996) 1.59
Responses of carotid artery in mice deficient in expression of the gene for endothelial NO synthase. Am J Physiol (1998) 1.57
Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice. Circ Res (2001) 1.50
Contrasting blood pressure effects of obesity in leptin-deficient ob/ob mice and agouti yellow obese mice. J Hypertens (1999) 1.42
Differential requirement for SLP-76 domains in T cell development and function. Immunity (2001) 1.36
Complementation of reduced survival, hypotension, and renal abnormalities in angiotensinogen-deficient mice by the human renin and human angiotensinogen genes. J Clin Invest (1997) 1.29
Efficient liver-specific deletion of a floxed human angiotensinogen transgene by adenoviral delivery of Cre recombinase in vivo. J Biol Chem (1999) 1.28
Retinoic acid-mediated activation of the mouse renin enhancer. J Biol Chem (2000) 1.25
Role of proximal promoter elements in regulation of renin gene transcription. J Biol Chem (1996) 1.22
Elevated blood pressure in transgenic mice with brain-specific expression of human angiotensinogen driven by the glial fibrillary acidic protein promoter. Circ Res (2001) 1.22
Functional expression of the human angiotensinogen gene in transgenic mice. J Biol Chem (1994) 1.22
Androgen-dependent regulation of human angiotensinogen expression in KAP-hAGT transgenic mice. Am J Physiol Renal Physiol (2001) 1.19
Gene transfer of endothelial nitric oxide synthase (eNOS) in eNOS-deficient mice. Am J Physiol (1999) 1.12
Spectinomycin resistance due to a mutation in an rRNA operon of Escherichia coli. J Bacteriol (1983) 1.11
Identification of three human renin mRNA isoforms from alternative tissue-specific transcriptional initiation. Physiol Genomics (2000) 1.11
Highly regulated cell type-restricted expression of human renin in mice containing 140- or 160-kilobase pair P1 phage artificial chromosome transgenes. J Biol Chem (1999) 1.09
Identification of cis elements in the cardiac troponin T gene conferring specific expression in cardiac muscle of transgenic mice. Circ Res (2000) 1.08
Appropriate tissue- and cell-specific expression of a single copy human angiotensinogen transgene specifically targeted upstream of the HPRT locus by homologous recombination. J Biol Chem (2000) 1.05
Munc18c regulates insulin-stimulated glut4 translocation to the transverse tubules in skeletal muscle. J Biol Chem (2000) 1.04
Transgenic mice expressing an intracellular fluorescent fusion of angiotensin II demonstrate renal thrombotic microangiopathy and elevated blood pressure. Am J Physiol Heart Circ Physiol (2010) 1.01
Transactivation of the human renin promoter by the cyclic AMP/protein kinase A pathway is mediated by both cAMP-responsive element binding protein-1 (CREB)-dependent and CREB-independent mechanisms in Calu-6 cells. J Biol Chem (1997) 0.99
The angiotensinogen gene is expressed in both astrocytes and neurons in murine central nervous system. Brain Res (1999) 0.98
NF-Y antagonizes renin enhancer function by blocking stimulatory transcription factors. Hypertension (2001) 0.97
Expression of murine renin genes during fetal development. Mol Endocrinol (1990) 0.97
Vectors for high-level expression of cDNAs controlled by tissue-specific promoters in transgenic mice. Biotechniques (2001) 0.96
Macrophage-specific expression of human lipoprotein lipase accelerates atherosclerosis in transgenic apolipoprotein e knockout mice but not in C57BL/6 mice. Arterioscler Thromb Vasc Biol (2001) 0.95
Species-specific differences in positive and negative regulatory elements in the renin gene enhancer. Circ Res (1999) 0.94
Impaired endothelial function in transgenic mice expressing both human renin and human angiotensinogen. Stroke (2000) 0.93
Conserved enhancer elements in human and mouse renin genes have different transcriptional effects in As4.1 cells. Circ Res (1997) 0.92
Allele-specific expression of the murine Ren-1 genes. J Biol Chem (1989) 0.91
Endogenous human renin expression and promoter activity in CALU-6, a pulmonary carcinoma cell line. Hypertension (1995) 0.91
Vascular biology in genetically altered mice : smaller vessels, bigger insight. Circ Res (2000) 0.89
Genetic evidence that lethality in angiotensinogen-deficient mice is due to loss of systemic but not renal angiotensinogen. J Biol Chem (2000) 0.89
Expression of the DBA/2J Ren-2 gene in the adrenal gland of transgenic mice. EMBO J (1989) 0.88
Biosynthesis of renin in mouse kidney tumor As4.1 cells. Eur J Biochem (1997) 0.87
JG cell expression and partial regulation of a human renin genomic transgene driven by a minimal renin promoter. Am J Physiol (1999) 0.87
Transcriptional and posttranscriptional mechanisms regulate human renin gene expression in Calu-6 cells. Am J Physiol (1996) 0.85
Understanding hypertension through genetic manipulation in mice. Kidney Int (2000) 0.83
Regulation of human renin mRNA expression and protein release in transgenic mice. Hypertension (1996) 0.83
Modifiable gene expression in mice: kidney-specific deletion of a target gene via the cre-loxP system. Exp Nephrol (1999) 0.82
Kidney is the only source of human plasma renin in 45-kb human renin transgenic mice. Circ Res (1999) 0.82
Human renin mRNA stability is increased in response to cAMP in Calu-6 cells. Hypertension (1999) 0.82
Transgenic mice for studies of the renin-angiotensin system in hypertension. Acta Physiol Scand (2004) 0.81
Tissue-specific expression of novel messenger ribonucleic acids cloned from a renin-expressing kidney tumor cell line (As4.1). Endocrinology (1995) 0.80
Regulatory elements required for human angiotensinogen expression in HepG2 cells are dispensable in transgenic mice. Hypertension (1998) 0.80
Transgenic and knockout mice to study the renin-angiotensin system and other interacting vasoactive pathways. Curr Hypertens Rep (2000) 0.79
Studies on the regulation of renin genes using transgenic mice. Clin Exp Hypertens A (1988) 0.78
Developmental expression of human angiotensinogen in transgenic mice. Am J Physiol (1998) 0.78
Renin promoter SV40 T-antigen transgenic mouse. A model of primary renal vascular hyperplasia. Hypertension (1991) 0.78
Downregulation of renin gene expression by interleukin-1. Hypertension (1997) 0.76
Chromosome 8 alterations accompany tumorigenesis in renin-SV40 T antigen transgenic mice. Cancer Res (1994) 0.76
Paradoxical regulation of short promoter human renin transgene by angiotensin ii. Hypertension (2001) 0.76
Use of transgenic and gene-targeted mice to model the genetic basis of hypertensive disorders. Proc Assoc Am Physicians (1997) 0.75
Inappropriate splicing of a chimeric gene containing a large internal exon results in exon skipping in transgenic mice. Nucleic Acids Res (1996) 0.75
Physiological insights from genetic manipulation of the renin-angiotensin system. News Physiol Sci (2001) 0.75
Transgenic animals in the study of blood pressure regulation and hypertension. Am J Physiol (1995) 0.75
Transgenesis and gene targeting in the mouse; tools for studying genetic determinants of hypertension. Trends Cardiovasc Med (1998) 0.75
Transgenic animal models as tools for studying renal developmental physiology. Pediatr Nephrol (1996) 0.75
Human renin 5'-flanking DNA to nucleotide-2750. DNA Seq (1995) 0.75
Transgenic animals as tools in hypertension research. Proc Soc Exp Biol Med (1994) 0.75