Published in FEBS Lett on February 11, 2000
De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination. Proc Natl Acad Sci U S A (2003) 1.43
Overlapping activation-induced cytidine deaminase hotspot motifs in Ig class-switch recombination. Proc Natl Acad Sci U S A (2011) 1.27
Class-Switch Recombination in the Absence of the IgH 3' Regulatory Region. J Immunol (2016) 0.75
Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J Exp Med (1992) 22.13
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell (2000) 20.83
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med (2000) 19.81
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity (1999) 12.36
PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol (2001) 12.26
Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2). Cell (2000) 9.99
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J (1992) 8.86
Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice. Science (2001) 8.31
Notch signalling controls pancreatic cell differentiation. Nature (1999) 7.18
Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. Int Immunol (1996) 6.79
Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells. J Biol Chem (1999) 6.67
Complete nucleotide sequence of mouse immunoglobulin mu gene and comparison with other immunoglobulin heavy chain genes. Nucleic Acids Res (1980) 5.20
Cloning and complete nucleotide sequence of mouse immunoglobulin gamma 1 chain gene. Cell (1979) 5.04
Identification of proliferating dendritic cell precursors in mouse blood. J Exp Med (1992) 5.03
Molecular cloning of cDNA encoding human interleukin-2 receptor. Nature (1984) 4.95
Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteins. Science (1993) 4.64
Generation of lymphohematopoietic cells from embryonic stem cells in culture. Science (1994) 4.41
Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts. Nat Cell Biol (2000) 4.31
Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses. Int Immunol (1998) 4.14
Organization of immunoglobulin heavy chain genes and allelic deletion model. Proc Natl Acad Sci U S A (1978) 3.95
Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis. J Biol Chem (1968) 3.81
Organization of the constant-region gene family of the mouse immunoglobulin heavy chain. Cell (1982) 3.72
Immunoglobulin genes. Annu Rev Immunol (1983) 3.72
Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch. Proc Natl Acad Sci U S A (1980) 3.70
The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro. J Exp Med (1994) 3.66
Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene. Genomics (1995) 3.60
In situ class switching and differentiation to IgA-producing cells in the gut lamina propria. Nature (2001) 3.58
Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells. J Exp Med (1998) 3.58
Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H). Curr Biol (1995) 3.46
Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives. Development (1997) 3.42
Dendritic cell progenitors phagocytose particulates, including bacillus Calmette-Guerin organisms, and sensitize mice to mycobacterial antigens in vivo. J Exp Med (1993) 3.39
Recognition sequence of a highly conserved DNA binding protein RBP-J kappa. Nucleic Acids Res (1994) 3.36
PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine. Proc Natl Acad Sci U S A (2001) 3.32
Disruption of the mouse RBP-J kappa gene results in early embryonic death. Development (1995) 3.30
Granulocytes, macrophages, and dendritic cells arise from a common major histocompatibility complex class II-negative progenitor in mouse bone marrow. Proc Natl Acad Sci U S A (1993) 3.25
Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome. Nat Genet (1998) 3.18
TCGF (IL 2)-receptor inducing factor(s). I. Regulation of IL 2 receptor on a natural killer-like cell line (YT cells). J Immunol (1985) 3.18
Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase. Nat Genet (1999) 3.17
The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development. Genes Dev (1999) 3.14
Conservation of the Notch signalling pathway in mammalian neurogenesis. Development (1997) 3.13
Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation. Curr Biol (2001) 3.13
Switch region of immunoglobulin Cmu gene is composed of simple tandem repetitive sequences. Nature (1981) 3.10
Multiple DNA fragment polymorphisms associated with immunoglobulin mu chain switch-like regions in man. Proc Natl Acad Sci U S A (1983) 3.07
Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells. Blood (2001) 3.01
Complete nucleotide sequence of immunoglobulin gamma2b chain gene cloned from newborn nouse DNA. Nature (1980) 2.97
Repetitive sequences in class-switch recombination regions of immunoglobulin heavy chain genes. Cell (1981) 2.84
High levels of a major histocompatibility complex II-self peptide complex on dendritic cells from the T cell areas of lymph nodes. J Exp Med (1997) 2.73
The recombination signal sequence-binding protein RBP-2N functions as a transcriptional repressor. Mol Cell Biol (1994) 2.71
PD-1: an inhibitory immunoreceptor involved in peripheral tolerance. Trends Immunol (2001) 2.71
Nucleotide sequence divergence of mouse immunoglobulin gamma 1 and gamma 2b chain genes and the hypothesis of intervening sequence-mediated domain transfer. Proc Natl Acad Sci U S A (1980) 2.68
Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesis. J Biol Chem (1999) 2.65
T-Independent immune response: new aspects of B cell biology. Science (2000) 2.63
The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus. J Exp Med (1998) 2.56
Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice. Nature (1992) 2.52
Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5. J Biol Chem (2000) 2.38
The nucleotide sequences of rearranged and germline immunoglobulin VH genes of a mouse myeloma MC101 and evolution of VH genes in mouse. J Biol Chem (1982) 2.37
Structure of human immunoglobulin gamma genes: implications for evolution of a gene family. Cell (1982) 2.32
Synthesis and antitumor activity of benzimidazolyl-1,3,5-triazine and benzimidazolylpyrimidine derivatives. Chem Pharm Bull (Tokyo) (2000) 2.30
A protein binding to the J kappa recombination sequence of immunoglobulin genes contains a sequence related to the integrase motif. Nature (1990) 2.29
Ordering of mouse immunoglobulin heavy chain genes by molecular cloning. Nature (1981) 2.28
A novel family of variable region genes of the human immunoglobulin heavy chain. J Mol Biol (1987) 2.27
27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells. J Biol Chem (2001) 2.27
The complete nucleotide sequence of mouse immunoglobin gamma 2a gene and evolution of heavy chain genes: further evidence for intervening sequence-mediated domain transfer. Nucleic Acids Res (1981) 2.26
Adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis by diphtheria toxin. J Biol Chem (1971) 2.23
Circular DNA is excised by immunoglobulin class switch recombination. Cell (1990) 2.22
Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region. Nucleic Acids Res (1998) 2.20
Organization and evolution of variable region genes of the human immunoglobulin heavy chain. J Mol Biol (1986) 2.17
B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40. Nature (1993) 2.14
Antroduodenal motility and transpyloric fluid movement in patients with diabetes studied using duplex sonography. Gastroenterology (1994) 2.12
Characterization of primary cultures of chondrocytes from type II collagen/beta-galactosidase transgenic mice. Matrix Biol (1994) 2.12
Characteristics of the clinical findings in patients with idiopathic thrombocytopenic purpura who are positive for anti-phospholipid antibodies. Intern Med (1997) 2.07
Notch1 and Notch3 instructively restrict bFGF-responsive multipotent neural progenitor cells to an astroglial fate. Neuron (2001) 2.06
Oxidative stress inhibits the repair of photodamage to the photosynthetic machinery. EMBO J (2001) 2.06
Isolation of a novel mouse gene MA-3 that is induced upon programmed cell death. Gene (1995) 2.05
A hallmark of active class switch recombination: transcripts directed by I promoters on looped-out circular DNAs. Proc Natl Acad Sci U S A (2001) 2.03
Differential regulation of human blood dendritic cell subsets by IFNs. J Immunol (2001) 2.02
Nucleotide sequences of switch regions of immunoglobulin C epsilon and C gamma genes and their comparison. J Biol Chem (1982) 2.01
Ionic and osmotic effects of NaCl-induced inactivation of photosystems I and II in Synechococcus sp. Plant Physiol (2000) 2.01
Organization of immunoglobulin genes: reiteration frequency of the mouse kappa chain constant region gene. Proc Natl Acad Sci U S A (1974) 2.00
Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis. J Biol Chem (1997) 1.98
High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells. Int Immunol (1996) 1.97
Purification of a peptidoglycan recognition protein from hemolymph of the silkworm, Bombyx mori. J Biol Chem (1996) 1.97
Interleukin 4 as an essential factor for in vitro clonal growth of murine connective tissue-type mast cells. J Exp Med (1987) 1.96
Structure and chromosomal localization of the human PD-1 gene (PDCD1). Genomics (1994) 1.96
LIM protein KyoT2 negatively regulates transcription by association with the RBP-J DNA-binding protein. Mol Cell Biol (1998) 1.96
The Drosophila homolog of the immunoglobulin recombination signal-binding protein regulates peripheral nervous system development. Cell (1992) 1.96
p93dis1, which is required for sister chromatid separation, is a novel microtubule and spindle pole body-associating protein phosphorylated at the Cdc2 target sites. Genes Dev (1995) 1.96
Immunoglobulin class switching. Cell (1984) 1.95
Active efflux of daunorubicin and adriamycin in sensitive and resistant sublines of P388 leukemia. Cancer Res (1979) 1.93
Nucleotide sequences of gene segments encoding membrane domains of immunoglobulin gamma chains. Proc Natl Acad Sci U S A (1982) 1.91
Structure of a rearranged gamma 1 chain gene and its implication to immunoglobulin class-switch mechanism. Proc Natl Acad Sci U S A (1981) 1.91
Field test of quantum key distribution in the Tokyo QKD Network. Opt Express (2011) 1.89
RBP-L, a transcription factor related to RBP-Jkappa. Mol Cell Biol (1997) 1.89
A transgenic model of autoimmune hemolytic anemia. J Exp Med (1992) 1.87