Published in Nucleic Acids Res on March 25, 1981
A catalogue of splice junction sequences. Nucleic Acids Res (1982) 39.41
Intron splicing: a conserved internal signal in introns of animal pre-mRNAs. Proc Natl Acad Sci U S A (1984) 4.71
The nucleotide sequence of a human immunoglobulin C gamma1 gene. Nucleic Acids Res (1982) 2.20
Molecular cloning of Ly-1, a membrane glycoprotein of mouse T lymphocytes and a subset of B cells: molecular homology to its human counterpart Leu-1/T1 (CD5). Proc Natl Acad Sci U S A (1987) 2.13
Linkage and sequence homology of two human immunoglobulin gamma heavy chain constant region genes. Proc Natl Acad Sci U S A (1982) 1.93
Nucleotide sequences of gene segments encoding membrane domains of immunoglobulin gamma chains. Proc Natl Acad Sci U S A (1982) 1.91
The 5' splice site: phylogenetic evolution and variable geometry of association with U1RNA. Nucleic Acids Res (1989) 1.60
The nucleotide sequence of the mouse immunoglobulin epsilon gene: comparison with the human epsilon gene sequence. EMBO J (1982) 1.55
Sequence of a human immunoglobulin gamma 3 heavy chain constant region gene: comparison with the other human C gamma genes. Nucleic Acids Res (1986) 1.45
Long terminal repeat-like elements flank a human immunoglobulin epsilon pseudogene that lacks introns. EMBO J (1982) 1.39
Cloning of human immunoglobulin epsilon chain genes: evidence for multiple C epsilon genes. Proc Natl Acad Sci U S A (1982) 1.30
Structural analysis of the murine IgG3 constant region gene. EMBO J (1984) 1.30
gamma Heavy chain disease in man: cDNA sequence supports partial gene deletion model. Proc Natl Acad Sci U S A (1982) 1.27
Point mutations cause the somatic diversification of IgM and IgG2a antiphosphorylcholine antibodies. J Exp Med (1988) 1.23
Unequal sister chromatid exchange. A mechanism affecting Ig gene arrangement and expression. J Exp Med (1985) 1.18
Further evidence that BALB/c and C57BL/6 gamma 2a genes originate from two distinct isotypes. EMBO J (1989) 1.14
Structure of the human immunoglobulin C epsilon 2 gene, a truncated pseudogene: implications for its evolutionary origin. Proc Natl Acad Sci U S A (1983) 1.06
The IgA heavy-chain gene family in rabbit: cloning and sequence analysis of 13 C alpha genes. EMBO J (1989) 1.02
Concordant evolution of coding and noncoding regions of DNA made possible by the universal rule of TA/CG deficiency-TG/CT excess. Proc Natl Acad Sci U S A (1989) 1.02
Concerted evolution of the mouse immunoglobulin gamma chain genes. EMBO J (1984) 0.92
The structure of the mouse immunoglobulin in gamma 3 membrane gene segment. Nucleic Acids Res (1983) 0.90
Three-dimensional structure of the Fab fragment of a neutralizing antibody to human rhinovirus serotype 2. Protein Sci (1992) 0.83
Hybrid gamma 2b-gamma 2a genes expressed in myeloma variants: evidence for homologous recombination. Proc Natl Acad Sci U S A (1983) 0.81
Expression and characterization of an enantioselective antigen-binding fragment directed against α-amino acids. Protein Expr Purif (2013) 0.75
Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol (1975) 503.08
Human fetal G gamma- and A gamma-globin genes: complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genes. Cell (1980) 14.88
The chromosomal arrangement of human alpha-like globin genes: sequence homology and alpha-globin gene deletions. Cell (1980) 9.13
The evolution and sequence comparison of two recently diverged mouse chromosomal beta--globin genes. Cell (1979) 8.11
The covalent structure of an entire gammaG immunoglobulin molecule. Proc Natl Acad Sci U S A (1969) 5.90
Domains and the hinge region of an immunoglobulin heavy chain are encoded in separate DNA segments. Nature (1979) 5.35
Complete nucleotide sequence of mouse immunoglobulin mu gene and comparison with other immunoglobulin heavy chain genes. Nucleic Acids Res (1980) 5.20
Cloning and complete nucleotide sequence of mouse immunoglobulin gamma 1 chain gene. Cell (1979) 5.04
The structure of one of the eight or more distinct chromosomal genes for human interferon-alpha. Nature (1980) 4.82
Mapping of heavy chain genes for mouse immunoglobulins M and D. Science (1980) 3.61
Molecular evolution of mRNA: a method for estimating evolutionary rates of synonymous and amino acid substitutions from homologous nucleotide sequences and its application. J Mol Evol (1980) 3.61
Implications of RNA-RNA splicing in evolution of eukaryotic cells. Science (1978) 3.39
Sequence of the cloned gene for the constant region of murine gamma 2b immunoglobulin heavy chain. Science (1979) 3.21
Immunoglobulin heavy chain gene organization in mice: analysis of a myeloma genomic clone containing variable and alpha constant regions. Proc Natl Acad Sci U S A (1979) 3.19
Complete nucleotide sequence of immunoglobulin gamma2b chain gene cloned from newborn nouse DNA. Nature (1980) 2.97
Nucleotide sequence divergence of mouse immunoglobulin gamma 1 and gamma 2b chain genes and the hypothesis of intervening sequence-mediated domain transfer. Proc Natl Acad Sci U S A (1980) 2.68
Mouse Cmu heavy chain immunoglobulin gene segment contains three intervening sequences separating domains. Nature (1980) 2.52
An immunoglobulin deletion mutant with implications for the heavy-chain switch and RNA splicing. Nature (1980) 2.41
Structure of the constant and 3' untranslated regions of the murine Balb/c gamma 2a heavy chain messenger RNA. Nucleic Acids Res (1980) 2.37
The ovalbumin gene region: common features in the organisation of three genes expressed in chicken oviduct under hormonal control. Nature (1979) 2.35
Structure of a family of rat amylase genes. Nature (1980) 2.19
Human immunoglobulin subclasses. Partial amino acid sequence of the constant region of a gamma 4 chain. Biochem J (1970) 2.11
Comparative analysis of the structural organization of two closely related vitellogenin genes in X. laevis. Cell (1980) 1.84
The complete sequence of the murine monoclonal immunoglobulin MOPC 173 (IgG2a): genetic implications. Ann Immunol (Paris) (1977) 1.82
Cloning immunoglobulin gamma 2b chain gene of mouse: characterization and partial sequence determination. Proc Natl Acad Sci U S A (1979) 1.80
Intervening sequences divide the gene for the constant region of mouse immunoglobulin mu chains into segments, each encoding a domain. Proc Natl Acad Sci U S A (1980) 1.73
Cloned pairs of variable region genes for immunoglobulin heavy chains isolated from a clone library of the entire mouse genome. Proc Natl Acad Sci U S A (1979) 1.71
Mutual homology of mouse immunoglobulin gamma-chain gene sequences. Biochemistry (1979) 1.55
Evolution of immunoglobulin subclasses. Primary structure of a murine myeloma gamma1 chain. J Biol Chem (1978) 1.43
An IgG2a-producing variant of an IgG2b-producing mouse myeloma cell line. Structural studies on the Fc region of parent and variant heavy chains. Biochemistry (1978) 1.33
Immunoglobulin gamma 1 heavy chain gene: structural gene sequences cloned in a bacterial plasmid. Gene (1980) 1.23
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell (2000) 20.83
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med (2000) 19.81
Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6-year study. Diabetes Res Clin Pract (1995) 12.51
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity (1999) 12.36
PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol (2001) 12.26
Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2). Cell (2000) 9.99
Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-beta gene regulatory elements. Cell (1988) 9.04
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J (1992) 8.86
Evolutionary relationship of archaebacteria, eubacteria, and eukaryotes inferred from phylogenetic trees of duplicated genes. Proc Natl Acad Sci U S A (1989) 8.45
Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice. Science (2001) 8.31
Notch signalling controls pancreatic cell differentiation. Nature (1999) 7.18
Sequence homology between retroviral reverse transcriptase and putative polymerases of hepatitis B virus and cauliflower mosaic virus. Nature (1983) 6.96
Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. Int Immunol (1996) 6.79
Total enteroscopy with a nonsurgical steerable double-balloon method. Gastrointest Endosc (2001) 6.76
Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells. J Biol Chem (1999) 6.67
Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes. Cell (1989) 6.11
Complete nucleotide sequence of mouse immunoglobulin mu gene and comparison with other immunoglobulin heavy chain genes. Nucleic Acids Res (1980) 5.20
Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's. Science (1989) 5.08
Cloning and complete nucleotide sequence of mouse immunoglobulin gamma 1 chain gene. Cell (1979) 5.04
Molecular cloning of cDNA encoding human interleukin-2 receptor. Nature (1984) 4.95
Nucleotide sequence divergence and functional constraint in mRNA evolution. Proc Natl Acad Sci U S A (1980) 4.71
Structural homology of Torpedo californica acetylcholine receptor subunits. Nature (1983) 4.70
Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteins. Science (1993) 4.64
Generation of lymphohematopoietic cells from embryonic stem cells in culture. Science (1994) 4.41
A giant nucleopore protein that binds Ran/TC4. Nature (1995) 4.36
Two types of amino acid substitutions in protein evolution. J Mol Evol (1979) 4.34
Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses. Int Immunol (1998) 4.14
Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria. Cell (1993) 4.04
Organization of immunoglobulin heavy chain genes and allelic deletion model. Proc Natl Acad Sci U S A (1978) 3.95
Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis. J Biol Chem (1968) 3.81
Organization of the constant-region gene family of the mouse immunoglobulin heavy chain. Cell (1982) 3.72
Immunoglobulin genes. Annu Rev Immunol (1983) 3.72
Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch. Proc Natl Acad Sci U S A (1980) 3.70
Primary structure of alpha-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence. Nature (1982) 3.69
Molecular evolution of mRNA: a method for estimating evolutionary rates of synonymous and amino acid substitutions from homologous nucleotide sequences and its application. J Mol Evol (1980) 3.61
Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene. Genomics (1995) 3.60
In situ class switching and differentiation to IgA-producing cells in the gut lamina propria. Nature (2001) 3.58
Nucleotide sequence of human endogenous retrovirus genome related to the mouse mammary tumor virus genome. J Virol (1986) 3.52
Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H). Curr Biol (1995) 3.46
Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives. Development (1997) 3.42
Recognition sequence of a highly conserved DNA binding protein RBP-J kappa. Nucleic Acids Res (1994) 3.36
PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine. Proc Natl Acad Sci U S A (2001) 3.32
Disruption of the mouse RBP-J kappa gene results in early embryonic death. Development (1995) 3.30
TCGF (IL 2)-receptor inducing factor(s). I. Regulation of IL 2 receptor on a natural killer-like cell line (YT cells). J Immunol (1985) 3.18
Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase. Nat Genet (1999) 3.17
Conservation of the Notch signalling pathway in mammalian neurogenesis. Development (1997) 3.13
Switch region of immunoglobulin Cmu gene is composed of simple tandem repetitive sequences. Nature (1981) 3.10
Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptors. J Exp Med (1999) 3.07
Multiple DNA fragment polymorphisms associated with immunoglobulin mu chain switch-like regions in man. Proc Natl Acad Sci U S A (1983) 3.07
Close structural resemblance between putative polymerase of a Drosophila transposable genetic element 17.6 and pol gene product of Moloney murine leukaemia virus. EMBO J (1985) 3.02
Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells. Blood (2001) 3.01
Complete nucleotide sequence of immunoglobulin gamma2b chain gene cloned from newborn nouse DNA. Nature (1980) 2.97
Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation. Genes Dev (1987) 2.86
Repetitive sequences in class-switch recombination regions of immunoglobulin heavy chain genes. Cell (1981) 2.84
The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons. Neuron (1995) 2.82
The recombination signal sequence-binding protein RBP-2N functions as a transcriptional repressor. Mol Cell Biol (1994) 2.71
PD-1: an inhibitory immunoreceptor involved in peripheral tolerance. Trends Immunol (2001) 2.71
Mouse-Musashi-1, a neural RNA-binding protein highly enriched in the mammalian CNS stem cell. Dev Biol (1996) 2.68
Nucleotide sequence divergence of mouse immunoglobulin gamma 1 and gamma 2b chain genes and the hypothesis of intervening sequence-mediated domain transfer. Proc Natl Acad Sci U S A (1980) 2.68
Successful en-bloc resection of large superficial tumors in the stomach and colon using sodium hyaluronate and small-caliber-tip transparent hood. Endoscopy (2003) 2.67
Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesis. J Biol Chem (1999) 2.65
T-Independent immune response: new aspects of B cell biology. Science (2000) 2.63
A role for Cajal-Retzius cells and reelin in the development of hippocampal connections. Nature (1997) 2.61
Molecular clock of silent substitution: at least six-fold preponderance of silent changes in mitochondrial genes over those in nuclear genes. J Mol Evol (1982) 2.58
The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus. J Exp Med (1998) 2.56
Primary structures of beta- and delta-subunit precursors of Torpedo californica acetylcholine receptor deduced from cDNA sequences. Nature (1983) 2.55
Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice. Nature (1992) 2.52
Nestin-EGFP transgenic mice: visualization of the self-renewal and multipotency of CNS stem cells. Mol Cell Neurosci (2001) 2.47
Cloning and sequence analysis of cDNA for the luminescent protein aequorin. Proc Natl Acad Sci U S A (1985) 2.42
Protein-bound acrolein: potential markers for oxidative stress. Proc Natl Acad Sci U S A (1998) 2.42
Extraordinarily high evolutionary rate of pseudogenes: evidence for the presence of selective pressure against changes between synonymous codons. Proc Natl Acad Sci U S A (1981) 2.42
Evolution of RNA polymerases and branching patterns of the three major groups of Archaebacteria. J Mol Evol (1991) 2.38
Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5. J Biol Chem (2000) 2.38
The nucleotide sequences of rearranged and germline immunoglobulin VH genes of a mouse myeloma MC101 and evolution of VH genes in mouse. J Biol Chem (1982) 2.37
Musashi1: an evolutionally conserved marker for CNS progenitor cells including neural stem cells. Dev Neurosci (2000) 2.36
Structure of human immunoglobulin gamma genes: implications for evolution of a gene family. Cell (1982) 2.32
A protein binding to the J kappa recombination sequence of immunoglobulin genes contains a sequence related to the integrase motif. Nature (1990) 2.29
Ordering of mouse immunoglobulin heavy chain genes by molecular cloning. Nature (1981) 2.28
A novel family of variable region genes of the human immunoglobulin heavy chain. J Mol Biol (1987) 2.27
Adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis by diphtheria toxin. J Biol Chem (1971) 2.23
Circular DNA is excised by immunoglobulin class switch recombination. Cell (1990) 2.22
Unusual evolutionary conservation and frequent DNA segment exchange in class I genes of the major histocompatibility complex. Proc Natl Acad Sci U S A (1983) 2.21
Nucleotide sequence of the staphylocoagulase gene: its unique COOH-terminal 8 tandem repeats. J Biochem (1987) 2.21
Nonmuscle and muscle tropomyosin isoforms are expressed from a single gene by alternative RNA splicing and polyadenylation. Mol Cell Biol (1986) 2.20
Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region. Nucleic Acids Res (1998) 2.20
Nucleotide sequence of the Syrian hamster intracisternal A-particle gene: close evolutionary relationship of type A particle gene to types B and D oncovirus genes. J Virol (1985) 2.20
Organization and evolution of variable region genes of the human immunoglobulin heavy chain. J Mol Biol (1986) 2.17
Reelin is a secreted glycoprotein recognized by the CR-50 monoclonal antibody. J Neurosci (1997) 2.17
Nucleotide sequence of the structural gene for colicin E1 and predicted structure of the protein. Proc Natl Acad Sci U S A (1982) 2.15
B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40. Nature (1993) 2.14