Published in Proc Natl Acad Sci U S A on October 01, 1976
Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin. Microbiol Rev (1992) 5.15
Membrane receptors for bacterial toxins. Microbiol Rev (1983) 2.41
Rabbit intestinal glycoprotein receptor for Escherichia coli heat-labile enterotoxin lacking affinity for cholera toxin. Infect Immun (1982) 2.08
Effects of thyrotropin on the thyroid cell membrane: hyperpolarization induced by hormone-receptor interaction. Proc Natl Acad Sci U S A (1977) 1.24
Binding of diphtheria toxin to phospholipids in liposomes. Proc Natl Acad Sci U S A (1980) 1.16
Bactericidal activity of fractionated granule contents from human polymorphonuclear leukocytes: role of bacterial membrane lipid. Infect Immun (1981) 0.94
Choleragen (cholera toxin): a bacterial lectin. Proc Natl Acad Sci U S A (1979) 0.94
Interaction of human chorionic gonadotropin with membrane components of rat testes. Proc Natl Acad Sci U S A (1978) 0.93
Reevaluation of the role of gangliosides in the binding and action of thyrotropin. Proc Natl Acad Sci U S A (1981) 0.80
Imperial Cancer Research Fund British Association for Cancer Research. Joint symposium held at the Royal College of Surgeons, Lincolns Inn Fields, London 30 November--1 December 1978. Abstracts of papers. Br J Cancer (1979) 0.75
Efficient trace-labelling of proteins with iodine. Nature (1958) 23.16
Interaction of Vibrio cholerae enterotoxin with cell membranes. Biochemistry (1973) 4.84
The mechanism of action of cholera toxin in pigeon erythrocyte lysates. J Biol Chem (1975) 4.22
Tissue receptor for cholera exotoxin: postulated structure from studies with GM1 ganglioside and related glycolipids. Infect Immun (1973) 4.08
Cholera toxin: interaction of subunits with ganglioside GM1. Science (1974) 3.11
Functional incorporation of ganglioside into intact cells: induction of choleragen responsiveness. Proc Natl Acad Sci U S A (1976) 2.14
Antibody-complement interaction with lipid model membranes. Biochim Biophys Acta (1972) 1.88
Mechanism of activation of adenylate cyclase by cholera toxin. Proc Natl Acad Sci U S A (1975) 1.65
Ganglioside biosynthesis in mouse cells: glycosyltransferase activities in normal and virally-transformed lines. Biochem Biophys Res Commun (1972) 1.19
Cholera toxin activation of adenylate cyclase in cancer cell membrane fragments. Proc Natl Acad Sci U S A (1975) 1.14
Comparative properties of four galactosyl lipids as antigens in liposomes. Immunochemistry (1974) 1.04
Influence of membrane composition on the interaction of a human monoclonal "anti-Forssman" immunoglobulin with liposomes. Biochemistry (1974) 0.99
Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis. Science (1997) 6.66
Replacement therapy for inherited enzyme deficiency--macrophage-targeted glucocerebrosidase for Gaucher's disease. N Engl J Med (1991) 6.09
Isolation of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP ribosylation factor (ARF) 1 and ARF3 that contains a Sec7-like domain. Proc Natl Acad Sci U S A (1996) 5.84
Enzymatic defect in Fabry's disease. Ceramidetrihexosidase deficiency. N Engl J Med (1967) 5.63
Enzyme replacement therapy in Fabry disease: a randomized controlled trial. JAMA (2001) 5.54
Herbal medicines and perioperative care. JAMA (2001) 5.05
Filipin-dependent inhibition of cholera toxin: evidence for toxin internalization and activation through caveolae-like domains. J Cell Biol (1998) 4.94
Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death. Proc Natl Acad Sci U S A (1996) 4.16
D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. Proc Natl Acad Sci U S A (2000) 3.71
Isolation and properties of phagocytic vesicles from polymorphonuclear leukocytes. J Clin Invest (1971) 3.39
Activation of adenylate cyclase by choleragen. Annu Rev Biochem (1979) 3.16
Transduction of nondividing cells using pseudotyped defective high-titer HIV type 1 particles. Proc Natl Acad Sci U S A (1996) 3.07
Hydrolysis of nicotinamide adenine dinucleotide by choleragen and its A protomer: possible role in the activation of adenylate cyclase. Proc Natl Acad Sci U S A (1976) 2.98
Procedure for determination of free and total cholesterol in micro- or nanogram amounts suitable for studies with cultured cells. J Lipid Res (1978) 2.92
Quantitative studies of phagocytosis by polymorphonuclear leukocytes: use of emulsions to measure the initial rate of phagocytosis. J Clin Invest (1972) 2.88
Mechanism of action of choleragen. Evidence for ADP-ribosyltransferase activity with arginine as an acceptor. J Biol Chem (1977) 2.76
Simple liquid-liquid partition system for isolation of labeled oleic acid from mixtures with glycerides. J Lipid Res (1969) 2.73
Molecules in the ARF orbit. J Biol Chem (1998) 2.66
Comprehensive evaluation of 35 patients with lymphangioleiomyomatosis. Chest (1999) 2.65
Pertussis toxin-catalyzed ADP-ribosylation of transducin. Cysteine 347 is the ADP-ribose acceptor site. J Biol Chem (1985) 2.64
Biosynthesis and function of gangliosides. Science (1976) 2.51
Niemann-Pick disease group C: clinical variability and diagnosis based on defective cholesterol esterification. A collaborative study on 70 patients. Clin Genet (1988) 2.50
High-titer human immunodeficiency virus type 1-based vector systems for gene delivery into nondividing cells. J Virol (1998) 2.47
The biotin-dependent enzymes. Adv Enzymol Relat Areas Mol Biol (1971) 2.45
The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargo. J Biol Chem (1999) 2.45
alpha-Galactosidase A deficient mice: a model of Fabry disease. Proc Natl Acad Sci U S A (1997) 2.43
Enzyme therapy in type 1 Gaucher disease: comparative efficacy of mannose-terminated glucocerebrosidase from natural and recombinant sources. Ann Intern Med (1995) 2.39
A defect in cholesterol esterification in Niemann-Pick disease (type C) patients. Proc Natl Acad Sci U S A (1985) 2.38
Mesenchymal precursor cells in the blood of normal individuals. Arthritis Res (2000) 2.37
Stimulation of glycerol production in fat cells by cholera toxin. Nature (1970) 2.34
The metabolism of sphingomyelin. II. Evidence of an enzymatic deficiency in Niemann-Pick diseae. Proc Natl Acad Sci U S A (1966) 2.32
ADP-ribosylation of guanyl nucleotide-binding regulatory proteins by bacterial toxins. Adv Enzymol Relat Areas Mol Biol (1988) 2.27
Purification of serine racemase: biosynthesis of the neuromodulator D-serine. Proc Natl Acad Sci U S A (1999) 2.27
Ganglioside inhibition of fibronectin-mediated cell adhesion to collagen. Proc Natl Acad Sci U S A (1979) 2.24
Intracellular processing of endothelial nitric oxide synthase isoforms associated with differences in severity of cardiopulmonary diseases: cleavage of proteins with aspartate vs. glutamate at position 298. Proc Natl Acad Sci U S A (2000) 2.21
Structure and function of ARF proteins: activators of cholera toxin and critical components of intracellular vesicular transport processes. J Biol Chem (1995) 2.18
Functional incorporation of ganglioside into intact cells: induction of choleragen responsiveness. Proc Natl Acad Sci U S A (1976) 2.14
The sphingolipidoses. N Engl J Med (1966) 2.13
A standardized psychiatric assessment scale for rating chronic psychotic patients. Acta Psychiatr Scand (1977) 2.13
Rapid, reliable ligation-independent cloning of PCR products using modified plasmid vectors. Biotechniques (1992) 2.09
beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein. Proc Natl Acad Sci U S A (1998) 2.08
Idiopathic nonspecific interstitial pneumonia: prognostic significance of cellular and fibrosing patterns: survival comparison with usual interstitial pneumonia and desquamative interstitial pneumonia. Am J Surg Pathol (2000) 2.07
Activation of adenylate cyclase by heat-labile Escherichia coli enterotoxin. Evidence for ADP-ribosyltransferase activity similar to that of choleragen. J Clin Invest (1978) 2.07
Demonstration of a deficiency of glucocerebroside-cleaving enzyme in Gaucher's disease. J Clin Invest (1966) 2.01
Infusion of alpha-galactosidase A reduces tissue globotriaosylceramide storage in patients with Fabry disease. Proc Natl Acad Sci U S A (2000) 2.00
Molecular identification of ADP-ribosylation factor mRNAs and their expression in mammalian cells. J Biol Chem (1991) 1.99
Acetyl coenzyme A carboxylase system of Escherichia coli. Purification and properties of the biotin carboxylase, carboxyltransferase, and carboxyl carrier protein components. J Biol Chem (1974) 1.99
Type C Niemann-Pick disease. Lysosomal accumulation and defective intracellular mobilization of low density lipoprotein cholesterol. J Biol Chem (1988) 1.98
Mortality variation across Australia: descriptive data for states and territories, and statistical divisions. Aust N Z J Public Health (2000) 1.98
Transcutaneous immunization: a human vaccine delivery strategy using a patch. Nat Med (2000) 1.98
Regulation of glycogen metabolism in polymorphonuclear leukocytes. J Biol Chem (1970) 1.98
Role of membrane gangliosides in the binding and action of bacterial toxins. J Membr Biol (1982) 1.97
Phagocytosis in chronic granulomatous disease and the Chediak-Higashi syndrome. N Engl J Med (1972) 1.96
Brefeldin A blocks the response of cultured cells to cholera toxin. Implications for intracellular trafficking in toxin action. J Biol Chem (1993) 1.95
Replacement therapy for inherited enzyme deficiency. Use of purified ceramidetrihexosidase in Fabry's disease. N Engl J Med (1973) 1.94
Acetyl coenzyme A carboxylase. Curr Top Cell Regul (1974) 1.94
D-serine as a neuromodulator: regional and developmental localizations in rat brain glia resemble NMDA receptors. J Neurosci (1997) 1.93
Extrapulmonary lymphangioleiomyomatosis (LAM): clinicopathologic features in 22 cases. Hum Pathol (2000) 1.93
Therapeutic response to intravenous infusions of glucocerebrosidase in a patient with Gaucher disease. Proc Natl Acad Sci U S A (1990) 1.88
Interaction of Sindbis virus with liposomal model membranes. J Virol (1975) 1.85
Lipids of alveolar macrophages, polymorphonuclear leukocytes, and their phagocytic vesicles. J Clin Invest (1972) 1.84
Isolation and properties of phagocytic vesicles. II. Alveolar macrophages. J Clin Invest (1972) 1.82
Oxidation of either methionine 351 or methionine 358 in alpha 1-antitrypsin causes loss of anti-neutrophil elastase activity. J Biol Chem (2000) 1.82
Therapy of leishmaniasis: superior efficacies of liposome-encapsulated drugs. Proc Natl Acad Sci U S A (1978) 1.82
Identification of antigens and antibodies specific for Pneumocystis carinii. J Immunol (1988) 1.81
Cytokine-mediated transcriptional induction of the human inducible nitric oxide synthase gene requires both activator protein 1 and nuclear factor kappaB-binding sites. J Biol Chem (1998) 1.81
Climate change and the integrity of science. Science (2010) 1.80
Diagnosis of gaucher's disease and niemann-pick disease with small samples of venous blood. Science (1967) 1.78
Purification and cloning of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors. J Biol Chem (1999) 1.78
Gangliosides in DNA virus-transformed and spontaneously transformed tumorigenic mouse cell lines. Proc Natl Acad Sci U S A (1969) 1.76
Complement-dependent damage to liposomes prepared from pure lipids and Forssman hapten. Biochemistry (1969) 1.75
Adult Gaucher's disease: kindred studies and demonstration of a deficiency of acid beta-glucosidase in cultured fibroblasts. Am J Hum Genet (1972) 1.74
Activation of rat brain phospholipase D by ADP-ribosylation factors 1,5, and 6: separation of ADP-ribosylation factor-dependent and oleate-dependent enzymes. Proc Natl Acad Sci U S A (1994) 1.74
Activation by thiol of the latent NAD glycohydrolase and ADP-ribosyltransferase activities of Bordetella pertussis toxin (islet-activating protein). J Biol Chem (1983) 1.74
Lymphangioleiomyomatosis: what do we know and what are we looking for? Eur Respir Rev (2011) 1.73
Regulation of NMDA receptors by cyclin-dependent kinase-5. Proc Natl Acad Sci U S A (2001) 1.73
Prophylaxis against ampicillin-associated diarrhea with a lactobacillus preparation. Am J Hosp Pharm (1979) 1.72
Lactosylceramide galactosidase: comparison with other sphingolipid hydrolases in developing rat brain. Brain Res (1969) 1.72
Prostaglandin E 1 effects on adenosine 3':5'-cyclic monophosphate concentration and phosphodiesterase activity in fibroblasts (mouse L cells-tissue culture-enzyme kinetics-prostaglandin homologues). Proc Natl Acad Sci U S A (1972) 1.68
Stimulation of choleragen enzymatic activities by GTP and two soluble proteins purified from bovine brain. J Biol Chem (1988) 1.67
Lymphangioleiomyomatosis: CT of diurnal variation of lymphangioleiomyomas. Radiology (2001) 1.67
ADP-ribosylation of adenylate cyclase by pertussis toxin. Effects on inhibitory agonist binding. J Biol Chem (1984) 1.67
Replacement therapy for inherited enzyme deficiency. Use of purified glucocerebrosidase in Gaucher's disease. N Engl J Med (1974) 1.67
Metachromatic leukodystrophy: diagnosis with samples of venous blood. Science (1968) 1.67
Mutations of glucocerebrosidase: discrimination of neurologic and non-neurologic phenotypes of Gaucher disease. Proc Natl Acad Sci U S A (1982) 1.64