Published in J Biol Chem on November 25, 1970
Isolation and properties of phagocytic vesicles from polymorphonuclear leukocytes. J Clin Invest (1971) 3.39
Quantitative studies of phagocytosis by polymorphonuclear leukocytes: use of emulsions to measure the initial rate of phagocytosis. J Clin Invest (1972) 2.88
Energy metabolism of human neutrophils during phagocytosis. J Clin Invest (1982) 2.37
Functional changes in human leukemic cell line HL-60. A model for myeloid differentiation. J Cell Biol (1979) 2.28
Effects of cholera enterotoxin on adenosine 3',5'-monophosphate and neutrophil function. Comparison with other compounds which stimulate leukocyte adenyl cyclase. J Clin Invest (1973) 2.16
Lipids of alveolar macrophages, polymorphonuclear leukocytes, and their phagocytic vesicles. J Clin Invest (1972) 1.84
Isolation of variants in phagocytosis of a macrophage-like continuous cell line. J Exp Med (1977) 1.54
Endocytosis of cholera toxin in GERL-like structures of murine neuroblastoma cells pretreated with GM1 ganglioside. Cholera toxin internalization into Neuroblastoma GERL. J Cell Biol (1979) 1.51
The effect of polystyrene beads on cyclic 3',5'-adenosine monophosphate concentration in leukocytes. J Clin Invest (1971) 1.49
Peripheral hyaline blebs (podosomes) of macrophages. J Cell Biol (1977) 1.35
The depression of phagocytosis by exogenous cyclic nucleotides, prostaglandins, and theophylline. J Cell Biol (1973) 1.29
Dissociation of opsonized particle phagocytosis and respiratory burst activity in an Epstein-Barr virus-infected myeloid cell line. J Cell Biol (1980) 1.19
G6PC3 mutations are associated with a major defect of glycosylation: a novel mechanism for neutrophil dysfunction. Glycobiology (2011) 1.08
Effects of anti-human neutrophil antibodies in vitro. Quantitative studies. J Clin Invest (1974) 1.02
Enhancement of hexose uptake in human polymorphonuclear leukocytes by activated complement component C5a. Proc Natl Acad Sci U S A (1979) 1.00
Cyclic adenosine monophosphate in phagocytizing granulocytes and alveolar macrophages. J Cell Biol (1973) 0.88
Synthesis of dipalmitoyl lecithin by alveolar macrophages. J Clin Invest (1972) 0.88
Impaired metabolic function and signaling defects in phagocytic cells in glycogen storage disease type 1b. J Clin Invest (1990) 0.86
Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP. Circ Res (1983) 6.42
Isolation of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP ribosylation factor (ARF) 1 and ARF3 that contains a Sec7-like domain. Proc Natl Acad Sci U S A (1996) 5.84
Control of cytoplasmic actin gel-sol transformation by gelsolin, a calcium-dependent regulatory protein. Nature (1979) 5.48
Nonmuscle actin-binding proteins. Annu Rev Cell Biol (1985) 5.46
Nitric oxide activates guanylate cyclase and increases guanosine 3':5'-cyclic monophosphate levels in various tissue preparations. Proc Natl Acad Sci U S A (1977) 4.90
Cyclic GMP synthesis and function. Pharmacol Rev (1987) 4.89
Actin-binding protein requirement for cortical stability and efficient locomotion. Science (1992) 4.66
Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. Proc Natl Acad Sci U S A (1991) 4.50
Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets. Cell (1995) 4.39
Modulation of gelsolin function by phosphatidylinositol 4,5-bisphosphate. Nature (1987) 3.99
Interactions of actin, myosin, and a new actin-binding protein of rabbit pulmonary macrophages. II. Role in cytoplasmic movement and phagocytosis. J Cell Biol (1976) 3.84
Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring. J Cell Biol (1990) 3.76
Stimulation of guanylate cyclase by sodium nitroprusside, nitroglycerin and nitric oxide in various tissue preparations and comparison to the effects of sodium azide and hydroxylamine. J Cyclic Nucleotide Res (1977) 3.70
Phagocytosis: recognition and ingestion. Semin Hematol (1975) 3.63
Role of cyclic GMP in the action of heat-stable enterotoxin of Escherichia coli. Nature (1978) 3.60
Cyclic guanosine monophosphate as a mediator of vasodilation. J Clin Invest (1986) 3.59
Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain. Nature (1986) 3.50
Isolation and properties of actin, myosin, and a new actinbinding protein in rabbit alveolar macrophages. J Biol Chem (1975) 3.41
Isolation and properties of phagocytic vesicles from polymorphonuclear leukocytes. J Clin Invest (1971) 3.39
Activation of adenylate cyclase by choleragen. Annu Rev Biochem (1979) 3.16
Calmodulin-dependent endothelium-derived relaxing factor/nitric oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial cells. Proc Natl Acad Sci U S A (1991) 3.15
Quantitative studies of phagocytosis. Kinetic effects of cations and heat-labile opsonin. J Cell Biol (1973) 3.14
Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin. Cell (1995) 3.08
Hydrolysis of nicotinamide adenine dinucleotide by choleragen and its A protomer: possible role in the activation of adenylate cyclase. Proc Natl Acad Sci U S A (1976) 2.98
Procedure for determination of free and total cholesterol in micro- or nanogram amounts suitable for studies with cultured cells. J Lipid Res (1978) 2.92
Interactions between actin, myosin, and an actin-binding protein from rabbit alveolar macrophages. Alveolar macrophage myosin Mg-2+-adenosine triphosphatase requires a cofactor for activation by actin. J Biol Chem (1975) 2.88
Quantitative studies of phagocytosis by polymorphonuclear leukocytes: use of emulsions to measure the initial rate of phagocytosis. J Clin Invest (1972) 2.88
The small GTPase RalA targets filamin to induce filopodia. Proc Natl Acad Sci U S A (1999) 2.87
Cytochalasin B and the structure of actin gels. J Mol Biol (1979) 2.81
Prestressed F-actin networks cross-linked by hinged filamins replicate mechanical properties of cells. Proc Natl Acad Sci U S A (2006) 2.80
Endothelium-dependent relaxation in rat aorta may be mediated through cyclic GMP-dependent protein phosphorylation. Nature (1984) 2.77
Mechanism of action of choleragen. Evidence for ADP-ribosyltransferase activity with arginine as an acceptor. J Biol Chem (1977) 2.76
Endocytic protein intersectin-l regulates actin assembly via Cdc42 and N-WASP. Nat Cell Biol (2001) 2.75
Ca2+ control of actin gelation. Interaction of gelsolin with actin filaments and regulation of actin gelation. J Biol Chem (1980) 2.73
Simple liquid-liquid partition system for isolation of labeled oleic acid from mixtures with glycerides. J Lipid Res (1969) 2.73
Molecules in the ARF orbit. J Biol Chem (1998) 2.66
Pertussis toxin-catalyzed ADP-ribosylation of transducin. Cysteine 347 is the ADP-ribose acceptor site. J Biol Chem (1985) 2.64
Isolation of disaturated phosphatidylcholine with osmium tetroxide. J Lipid Res (1976) 2.63
Purification of a soluble isoform of guanylyl cyclase-activating-factor synthase. Proc Natl Acad Sci U S A (1991) 2.58
Resemblance of actin-binding protein/actin gels to covalently crosslinked networks. Nature (1990) 2.58
Myosin in polymorphonuclear leukocytes. J Biol Chem (1973) 2.55
Contractile proteins in leukocyte function. Semin Hematol (1983) 2.55
Activation of intestinal guanylate cyclase by heat-stable enterotoxin of Escherichia coli: studies of tissue specificity, potential receptors, and intermediates. J Infect Dis (1980) 2.52
Signaling pathways and cell mechanics involved in wound closure by epithelial cell sheets. Curr Biol (2000) 2.52
The opsonic fragment of the third component of human complement (C3). J Exp Med (1975) 2.51
Distribution of actin-binding protein and myosin in macrophages during spreading and phagocytosis. J Cell Biol (1980) 2.45
Nobel laureates' letter to President Bush. Washington Post (2001) 2.43
Guanylate cyclase: activation by azide, nitro compounds, nitric oxide, and hydroxyl radical and inhibition by hemoglobin and myoglobin. Adv Cyclic Nucleotide Res (1978) 2.43
Interactions of actin, myosin, and an actin-binding protein of rabbit pulmonary macrophages. III. Effects of cytochalasin B. J Cell Biol (1976) 2.42
Phagocytosis (third of three parts). N Engl J Med (1974) 2.41
N omega-nitro-L-arginine: a potent inhibitor of endothelium-derived relaxing factor formation. Eur J Pharmacol (1990) 2.40
Neutrophil action dysfunction and abnormal neutrophil behavior. N Engl J Med (1974) 2.35
Stimulation of glycerol production in fat cells by cholera toxin. Nature (1970) 2.34
Isoforms of nitric oxide synthase. Characterization and purification from different cell types. Biochem Pharmacol (1991) 2.34
Endothelium-dependent and nitrovasodilator-induced relaxation of vascular smooth muscle: role of cyclic GMP. J Cyclic Nucleotide Protein Phosphor Res (1983) 2.34
An inherited abnormality of neutrophil adhesion. Its genetic transmission and its association with a missing protein. N Engl J Med (1980) 2.32
Filamin A, the Arp2/3 complex, and the morphology and function of cortical actin filaments in human melanoma cells. J Cell Biol (2001) 2.29
Myeloperoxidase-mediated iodination by granulocytes. Intracellular site of operation and some regulating factors. J Clin Invest (1974) 2.28
ADP-ribosylation of guanyl nucleotide-binding regulatory proteins by bacterial toxins. Adv Enzymol Relat Areas Mol Biol (1988) 2.27
The gelation of actin by actin-binding protein. J Biol Chem (1978) 2.27
Atrial natriuretic factor elicits an endothelium-independent relaxation and activates particulate guanylate cyclase in vascular smooth muscle. Proc Natl Acad Sci U S A (1984) 2.26
Enhanced motility in NIH 3T3 fibroblasts that overexpress gelsolin. Science (1991) 2.26
Serum-dependent phagocytosis of paraffin oil emulsified with bacterial lipopolysaccharide. J Exp Med (1973) 2.25
Evaluation of opsonic and leukocyte function with a spectrophotometric test in patients with infection and with phagocytic disorders. Blood (1973) 2.25
Insulin secretion from pancreatic B cells caused by L-arginine-derived nitrogen oxides. Science (1992) 2.25
Gelsolin is a downstream effector of rac for fibroblast motility. EMBO J (1998) 2.23
The mechanical properties of actin gels. Elastic modulus and filament motions. J Biol Chem (1994) 2.23
Actin-binding protein promotes the bipolar and perpendicular branching of actin filaments. J Cell Biol (1980) 2.22
Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A. Nature (2011) 2.22
Structure and function of ARF proteins: activators of cholera toxin and critical components of intracellular vesicular transport processes. J Biol Chem (1995) 2.18
Interactions of gelsolin and gelsolin-actin complexes with actin. Effects of calcium on actin nucleation, filament severing, and end blocking. Biochemistry (1985) 2.16
Atrial natriuretic factor selectively activates particulate guanylate cyclase and elevates cyclic GMP in rat tissues. J Biol Chem (1984) 2.15
Functional incorporation of ganglioside into intact cells: induction of choleragen responsiveness. Proc Natl Acad Sci U S A (1976) 2.14
Cloned human brain nitric oxide synthase is highly expressed in skeletal muscle. FEBS Lett (1993) 2.14
A standardized psychiatric assessment scale for rating chronic psychotic patients. Acta Psychiatr Scand (1977) 2.13
Polyphosphoinositide micelles and polyphosphoinositide-containing vesicles dissociate endogenous gelsolin-actin complexes and promote actin assembly from the fast-growing end of actin filaments blocked by gelsolin. J Biol Chem (1987) 2.08
beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein. Proc Natl Acad Sci U S A (1998) 2.08
Novel effects of nitric oxide. Annu Rev Pharmacol Toxicol (2001) 2.08
Ca2+ control of actin filament length. Effects of macrophage gelsolin on actin polymerization. J Biol Chem (1981) 2.07
Purification and structural properties of gelsolin, a Ca2+-activated regulatory protein of macrophages. J Biol Chem (1980) 2.06
Structure of macrophage actin-binding protein molecules in solution and interacting with actin filaments. J Mol Biol (1981) 2.04
Distribution of actin-binding protein and myosin in polymorphonuclear leukocytes during locomotion and phagocytosis. Cell (1981) 2.03
Prevention of degradation of human polymorphonuclear leukocyte proteins by diisopropylfluorophosphate. Blood (1980) 2.01
Molecular identification of ADP-ribosylation factor mRNAs and their expression in mammalian cells. J Biol Chem (1991) 1.99
Structure and mobility of actin filaments as measured by quasielastic light scattering, viscometry, and electron microscopy. J Biol Chem (1986) 1.99
Pulmonary alveolar type II epithelial cells synthesize and secrete proteins of the classical and alternative complement pathways. J Clin Invest (1988) 1.99
Regulation of adenosine cyclic 3',5'-monophosphate and guanosine cyclic 3',5'-monophosphate levels and contractility in bovine tracheal smooth muscle. Mol Pharmacol (1977) 1.98
Reversible binding of actin to gelsolin and profilin in human platelet extracts. J Cell Biol (1987) 1.97
Phagocytosis in chronic granulomatous disease and the Chediak-Higashi syndrome. N Engl J Med (1972) 1.96
Nitric oxide synthase in macula densa regulates glomerular capillary pressure. Proc Natl Acad Sci U S A (1992) 1.93
Phagocytes as carcinogens: malignant transformation produced by human neutrophils. Science (1985) 1.90
Surfactant protein A predicts survival in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (1995) 1.85
A neutrophil disorder induced by capnocytophaga, a dental micro-organism. N Engl J Med (1979) 1.84
Lipids of alveolar macrophages, polymorphonuclear leukocytes, and their phagocytic vesicles. J Clin Invest (1972) 1.84