Published in Trends Biochem Sci on April 01, 2000
The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks. Mol Cell Biol (2004) 3.94
Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstrand cross-links in mammalian cells. Mol Cell Biol (2000) 3.57
Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase. Genes Dev (2005) 2.91
Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells. Mol Cell Biol (2002) 2.73
Transcriptional response of Saccharomyces cerevisiae to DNA-damaging agents does not identify the genes that protect against these agents. Proc Natl Acad Sci U S A (2002) 2.72
Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage. EMBO J (2002) 2.45
DNA replication meets genetic exchange: chromosomal damage and its repair by homologous recombination. Proc Natl Acad Sci U S A (2001) 2.11
RAD18 and RAD54 cooperatively contribute to maintenance of genomic stability in vertebrate cells. EMBO J (2002) 2.06
Epigenetic regulation of heterochromatic DNA stability. Curr Opin Genet Dev (2008) 1.80
The karyopherin Kap142p/Msn5p mediates nuclear import and nuclear export of different cargo proteins. J Cell Biol (2001) 1.78
Links between replication and recombination in Saccharomyces cerevisiae: a hypersensitive requirement for homologous recombination in the absence of Rad27 activity. Proc Natl Acad Sci U S A (2001) 1.54
Homologous DNA recombination in vertebrate cells. Proc Natl Acad Sci U S A (2001) 1.52
Replication fork collapse at replication terminator sequences. EMBO J (2002) 1.48
Endogenous DNA abasic sites cause cell death in the absence of Apn1, Apn2 and Rad1/Rad10 in Saccharomyces cerevisiae. EMBO J (2002) 1.38
Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I. J Cell Biol (2005) 1.38
A targeted RNAi screen for genes involved in chromosome morphogenesis and nuclear organization in the Caenorhabditis elegans germline. Genetics (2002) 1.35
Telomere resolution in the Lyme disease spirochete. EMBO J (2001) 1.28
Involvement of mouse Rev3 in tolerance of endogenous and exogenous DNA damage. Mol Cell Biol (2002) 1.28
A time-invariant principle of genome evolution. Proc Natl Acad Sci U S A (2010) 1.24
Reverse genetic studies of homologous DNA recombination using the chicken B-lymphocyte line, DT40. Philos Trans R Soc Lond B Biol Sci (2001) 1.20
Discovery of a novel function for human Rad51: maintenance of the mitochondrial genome. J Biol Chem (2010) 1.08
The stacked-X DNA Holliday junction and protein recognition. J Mol Recognit (2006) 1.08
Interplay between DNA replication, recombination and repair based on the structure of RecG helicase. Philos Trans R Soc Lond B Biol Sci (2004) 1.07
Repair of topoisomerase-mediated DNA damage in bacteriophage T4. Genetics (2001) 1.06
A saccharomyces cerevisiae RNase H2 interaction network functions to suppress genome instability. Mol Cell Biol (2014) 1.00
SIR functions are required for the toleration of an unrepaired double-strand break in a dispensable yeast chromosome. Mol Cell Biol (2001) 0.95
Strand exchange activity of human recombination protein Rad52. Proc Natl Acad Sci U S A (2004) 0.95
Reducing MCM levels in human primary T cells during the G(0)-->G(1) transition causes genomic instability during the first cell cycle. Oncogene (2010) 0.94
Functional interactions of meiotic recombination factors Rdh54 and Dmc1. DNA Repair (Amst) (2008) 0.88
OsRAD51C is essential for double-strand break repair in rice meiosis. Front Plant Sci (2014) 0.87
Rad51 presynaptic filament stabilization function of the mouse Swi5-Sfr1 heterodimeric complex. Nucleic Acids Res (2012) 0.85
DNA repair pathway selection caused by defects in TEL1, SAE2, and de novo telomere addition generates specific chromosomal rearrangement signatures. PLoS Genet (2014) 0.84
Gain- and loss-of-function of Rhp51, a Rad51 homolog in fission yeast, reveals dissimilarities in chromosome integrity. Nucleic Acids Res (2001) 0.83
Human Rad51 promotes mitochondrial DNA synthesis under conditions of increased replication stress. Mitochondrion (2013) 0.83
Focused genetic recombination of bacteriophage t4 initiated by double-strand breaks. Genetics (2002) 0.82
The trans-autostimulatory activity of Rad27 suppresses dna2 defects in Okazaki fragment processing. J Biol Chem (2012) 0.78
Nascent DNA synthesis during homologous recombination is synergistically promoted by the rad51 recombinase and DNA homology. Genetics (2014) 0.78
Non-canonical uracil processing in DNA gives rise to double-strand breaks and deletions: relevance to class switch recombination. Nucleic Acids Res (2016) 0.77
Pathways and Mechanisms that Prevent Genome Instability in Saccharomyces cerevisiae. Genetics (2017) 0.75
The double-strand-break repair model for recombination. Cell (1983) 31.21
Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (1999) 19.25
Recombinational repair of DNA damage in Escherichia coli and bacteriophage lambda. Microbiol Mol Biol Rev (1999) 6.92
Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes. Cell (1980) 5.48
Unequal crossing over in the ribosomal DNA of Saccharomyces cerevisiae. Nature (1980) 5.12
RuvAB acts at arrested replication forks. Cell (1998) 5.08
Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitro. Nature (1994) 4.96
DNA end-joining: from yeast to man. Trends Biochem Sci (1998) 4.94
Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A. Nature (1998) 4.93
Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase. Genes Dev (1997) 4.57
Function of yeast Rad52 protein as a mediator between replication protein A and the Rad51 recombinase. J Biol Chem (1997) 4.53
Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication. Proc Natl Acad Sci U S A (1996) 4.49
DNA strand annealing is promoted by the yeast Rad52 protein. Proc Natl Acad Sci U S A (1996) 4.42
Replication factors required for SV40 DNA replication in vitro. I. DNA structure-specific recognition of a primer-template junction by eukaryotic DNA polymerases and their accessory proteins. J Biol Chem (1991) 4.32
Stimulation by Rad52 of yeast Rad51-mediated recombination. Nature (1998) 4.31
DNA double-strand breaks caused by replication arrest. EMBO J (1997) 4.18
Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants. Nat Genet (1999) 4.18
Mating-type gene switching in Saccharomyces cerevisiae. Annu Rev Genet (1998) 4.08
Stable DNA replication: interplay between DNA replication, homologous recombination, and transcription. Microbiol Mol Biol Rev (1997) 3.90
Role of DNA polymerase alpha and DNA primase in simian virus 40 DNA replication in vitro. Proc Natl Acad Sci U S A (1986) 3.85
Complex formation in yeast double-strand break repair: participation of Rad51, Rad52, Rad55, and Rad57 proteins. Proc Natl Acad Sci U S A (1995) 3.79
Catalysis of homologous DNA pairing by yeast Rad51 and Rad54 proteins. Nature (1998) 3.75
DNA recombination: the replication connection. Trends Biochem Sci (1999) 3.32
Homologous recombination and the roles of double-strand breaks. Trends Biochem Sci (1995) 3.10
DNA damage and checkpoint pathways: molecular anatomy and interactions with repair. Cell (1998) 3.04
Double-strand break repair in yeast requires both leading and lagging strand DNA polymerases. Cell (1999) 2.89
"Break copy" duplication: a model for chromosome fragment formation in Saccharomyces cerevisiae. Genetics (1997) 2.76
Studies on the activator 1 protein complex, an accessory factor for proliferating cell nuclear antigen-dependent DNA polymerase delta. J Biol Chem (1991) 2.70
The in vitro replication of DNA containing the SV40 origin. J Biol Chem (1990) 2.68
Rad52 forms ring structures and co-operates with RPA in single-strand DNA annealing. Genes Cells (1998) 2.66
Chromosome break-induced DNA replication leads to nonreciprocal translocations and telomere capture. Genetics (1998) 2.55
Replication factors required for SV40 DNA replication in vitro. II. Switching of DNA polymerase alpha and delta during initiation of leading and lagging strand synthesis. J Biol Chem (1991) 2.51
Mechanism of elongation of primed DNA by DNA polymerase delta, proliferating cell nuclear antigen, and activator 1. Proc Natl Acad Sci U S A (1990) 2.49
Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repair. Mol Cell (1998) 2.49
A novel allele of Saccharomyces cerevisiae RFA1 that is deficient in recombination and repair and suppressible by RAD52. Mol Cell Biol (1995) 2.21
Two alternative mechanisms for initiation of DNA replication forks in bacteriophage T4: priming by RNA polymerase and by recombination. Proc Natl Acad Sci U S A (1982) 2.11
Purification and characterization of the T4 bacteriophage uvsX protein. J Biol Chem (1986) 1.92
The essential role of recombination in phage T4 growth. Annu Rev Genet (1987) 1.89
Studies of the interaction between Rad52 protein and the yeast single-stranded DNA binding protein RPA. Mol Cell Biol (1998) 1.74
Gene conversion tracts stimulated by HOT1-promoted transcription are long and continuous. Genetics (1990) 1.66
A chromosome containing HOT1 preferentially receives information during mitotic interchromosomal gene conversion. Genetics (1990) 1.55
Double-strand break-induced recombination in eukaryotes. Prog Nucleic Acid Res Mol Biol (1998) 1.28
The role of homologous recombination processes in the repair of severe forms of DNA damage in mammalian cells. Biochimie (1999) 1.21
Mutations in conserved yeast DNA primase domains impair DNA replication in vivo. Proc Natl Acad Sci U S A (1991) 1.12
A new view of V(D)J recombination. Genes Cells (1996) 0.94
Damage to DNA and chromatin structure from ionizing radiations, and the radiation sensitivities of mammalian cells. Prog Nucleic Acid Res Mol Biol (1990) 0.88
Meiosis: Avoiding inappropriate relationships. Curr Biol (1998) 0.81
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci U S A (1998) 9.66
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet (2001) 9.34
Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell (1998) 8.31
A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair. Cell (1997) 5.49
Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae. Cell (2001) 4.96
Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants. Nat Genet (1999) 4.18
Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions. Genetics (1992) 3.97
Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae. Nature (2001) 3.77
Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2. Proc Natl Acad Sci U S A (1997) 3.66
Identification and purification of a single-stranded-DNA-specific exonuclease encoded by the recJ gene of Escherichia coli. Proc Natl Acad Sci U S A (1989) 3.65
SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination. Nat Genet (2001) 3.60
Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae. Genetics (1994) 3.52
MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast. Science (1994) 3.19
Meiotic pachytene arrest in MLH1-deficient mice. Cell (1996) 3.18
Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families. Nat Med (1996) 3.07
The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations. Proc Natl Acad Sci U S A (1998) 2.77
Biochemical interaction of the Escherichia coli RecF, RecO, and RecR proteins with RecA protein and single-stranded DNA binding protein. Proc Natl Acad Sci U S A (1993) 2.77
Exonuclease I of Saccharomyces cerevisiae functions in mitotic recombination in vivo and in vitro. Mol Cell Biol (1997) 2.73
Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins. Genetics (1992) 2.50
Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repair. Mol Cell (1998) 2.49
MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice. Genes Dev (2000) 2.49
The genetic dependence of recombination in recD mutants of Escherichia coli. Genetics (1988) 2.49
The role of heteroduplex correction in gene conversion in Saccharomyces cerevisiae. Nature (1987) 2.38
Identification of mismatch repair genes and their role in the development of cancer. Curr Opin Genet Dev (1995) 2.37
Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism. Genetics (1998) 2.37
Characterization of hereditary nonpolyposis colorectal cancer families from a population-based series of cases. J Natl Cancer Inst (2000) 2.37
Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines. Cancer Res (1995) 2.35
Specificity of mismatch repair following transformation of Saccharomyces cerevisiae with heteroduplex plasmid DNA. Proc Natl Acad Sci U S A (1989) 2.33
An essential Saccharomyces cerevisiae single-stranded DNA binding protein is homologous to the large subunit of human RP-A. EMBO J (1990) 2.28
Strand exchange protein 1 from Saccharomyces cerevisiae. A novel multifunctional protein that contains DNA strand exchange and exonuclease activities. J Biol Chem (1991) 2.26
Protein interactions in genetic recombination in Escherichia coli. Interactions involving RecO and RecR overcome the inhibition of RecA by single-stranded DNA-binding protein. J Biol Chem (1994) 2.26
Genetic and physical analysis of plasmid recombination in recB recC sbcB and recB recC sbcA Escherichia coli K-12 mutants. Genetics (1989) 2.22
Characterization of DNA-binding and strand-exchange stimulation properties of y-RPA, a yeast single-strand-DNA-binding protein. J Mol Biol (1992) 2.19
Interpretation of genetic test results for hereditary nonpolyposis colorectal cancer: implications for clinical predisposition testing. JAMA (1999) 2.14
Sensitivity and specificity of clinical criteria for hereditary non-polyposis colorectal cancer associated mutations in MSH2 and MLH1. J Med Genet (2000) 2.05
Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex. Nat Genet (2000) 2.05
Repair of heteroduplex plasmid DNA after transformation into Saccharomyces cerevisiae. Mol Cell Biol (1986) 1.98
Correction of hypermutability, N-methyl-N'-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6. Cancer Res (1997) 1.96
Chloroplast DNA from higher plants replicates by both the Cairns and the rolling circle mechanism. Nature (1975) 1.94
Molecular and genetic analysis of the gene encoding the Saccharomyces cerevisiae strand exchange protein Sep1. Mol Cell Biol (1991) 1.92
Synthetic lethality of sep1 (xrn1) ski2 and sep1 (xrn1) ski3 mutants of Saccharomyces cerevisiae is independent of killer virus and suggests a general role for these genes in translation control. Mol Cell Biol (1995) 1.88
Biochemical characterization of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 complex and mispaired bases in DNA. J Biol Chem (1999) 1.84
exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair. Mol Cell Biol (2001) 1.79
Targeting of nonexpressed genes in embryonic stem cells via homologous recombination. Science (1989) 1.75
Regulation and intracellular localization of Saccharomyces cerevisiae strand exchange protein 1 (Sep1/Xrn1/Kem1), a multifunctional exonuclease. Mol Cell Biol (1995) 1.74
Saccharomyces cerevisiae MSH2, a mispaired base recognition protein, also recognizes Holliday junctions in DNA. J Mol Biol (1997) 1.71
Denaturation mapping studies on the circular chloroplast deoxyribonucleic acid from pea leaves. J Biol Chem (1975) 1.70
Purification and preliminary characterization of the Escherichia coli K-12 recF protein. J Bacteriol (1990) 1.70
MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in S. cerevisiae. Mol Cell (1999) 1.69
The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression. Cancer Res (2000) 1.68
Identification and characterization of the Escherichia coli RecT protein, a protein encoded by the recE region that promotes renaturation of homologous single-stranded DNA. J Bacteriol (1993) 1.63
Identification of a human gene encoding a homologue of Saccharomyces cerevisiae EXO1, an exonuclease implicated in mismatch repair and recombination. Cancer Res (1998) 1.59
Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas. Hum Mol Genet (1995) 1.57
Intron splice acceptor site sequence variation in the hereditary non-polyposis colorectal cancer gene hMSH2. Eur J Cancer (1994) 1.54
Saccharomyces cerevisiae pol30 (proliferating cell nuclear antigen) mutations impair replication fidelity and mismatch repair. Mol Cell Biol (1999) 1.54
Checkpoint-dependent activation of mutagenic repair in Saccharomyces cerevisiae pol3-01 mutants. Mol Cell (2000) 1.53
Mapping of Escherichia coli chromosomal Tn5 and F insertions by pulsed field gel electrophoresis. Genetics (1988) 1.53
Purification and characterization of MSH1, a yeast mitochondrial protein that binds to DNA mismatches. J Biol Chem (1994) 1.52
Initial description of the human NLRP3 promoter. Genes Immun (2008) 1.52
Identification of a locus on chromosome 1q44 for familial cold urticaria. Am J Hum Genet (2000) 1.51
Nucleotide sequence of the Escherichia coli recJ chromosomal region and construction of recJ-overexpression plasmids. J Bacteriol (1991) 1.49
Homologous pairing and strand exchange promoted by the Escherichia coli RecT protein. Proc Natl Acad Sci U S A (1994) 1.43
DNA strand invasion promoted by Escherichia coli RecT protein. J Biol Chem (1998) 1.42
Functional analysis of human MLH1 mutations in Saccharomyces cerevisiae. Nat Genet (1998) 1.33
The sep1 mutant of Saccharomyces cerevisiae arrests in pachytene and is deficient in meiotic recombination. Genetics (1995) 1.30
Physical interaction between components of DNA mismatch repair and nucleotide excision repair. Proc Natl Acad Sci U S A (1998) 1.24
Mononucleotide microsatellite instability and germline MSH6 mutation analysis in early onset colorectal cancer. J Med Genet (1999) 1.23
Novel dominant mutations in Saccharomyces cerevisiae MSH6. Nat Genet (2000) 1.22
The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis. Cancer Res (2001) 1.21
Mutational analysis of exoribonuclease I from Saccharomyces cerevisiae. Nucleic Acids Res (1998) 1.20
Multiple functions of MutS- and MutL-related heterocomplexes. Proc Natl Acad Sci U S A (1999) 1.19
Purification and characterization of a protein from Saccharomyces cerevisiae that binds tightly to single-stranded DNA and stimulates a cognate strand exchange protein. Biochemistry (1989) 1.18
'Saccharomyces cerevisiae MSH2/6 complex interacts with Holliday junctions and facilitates their cleavage by phage resolution enzymes. J Biol Chem (1999) 1.15
Renaturation of DNA by a Saccharomyces cerevisiae protein that catalyzes homologous pairing and strand exchange. J Biol Chem (1988) 1.11
Analysis of the recE locus of Escherichia coli K-12 by use of polyclonal antibodies to exonuclease VIII. J Bacteriol (1988) 1.11
The yeast HSM3 gene is not involved in DNA mismatch repair in rapidly dividing cells. Genetics (2000) 1.09
Cloning and characterization of the human and Caenorhabditis elegans homologs of the Saccharomyces cerevisiae MSH5 gene. Genomics (1998) 1.03
The effect of DNA mismatches on the ATPase activity of MSH1, a protein in yeast mitochondria that recognizes DNA mismatches. J Biol Chem (1994) 1.02
The activity of the Saccharomyces cerevisiae strand exchange protein 1 intrinsic exonuclease during joint molecule formation. J Biol Chem (1994) 0.94
The MER3 helicase involved in meiotic crossing over is stimulated by single-stranded DNA-binding proteins and unwinds DNA in the 3' to 5' direction. J Biol Chem (2001) 0.93
Effect of terminal non-homology on intramolecular recombination of linear plasmid substrates in Escherichia coli. J Mol Biol (1992) 0.91
Accurate, high-throughput "snapshot" detection of hMLH1 mutations by two-dimensional DNA electrophoresis. Genet Test (1998) 0.84
Origin, transmission, and segregation of mitochondrial DNA dimers in mouse hybrid and cybrid cell lines. Somat Cell Mol Genet (1984) 0.81
Regulation of the reverse transcriptase of human immunodeficiency virus type 1 by dNTPs. Proc Natl Acad Sci U S A (1992) 0.79
Characterization of the interaction of Saccharomyces cerevisiae strand exchange protein 1 with DNA. J Biol Chem (1994) 0.79
Low frequency of hMSH2 mutations in Swedish HNPCC families. Int J Cancer (1997) 0.78
Guarding against mutation. Nature (2000) 0.77
Saccharomyces cerevisiae proteins involved in hybrid DNA formation in vitro. Biochimie (1991) 0.75
Keystone Symposia on Molecular and Cellular Biology: 'The molecular basis of cancer'. Organizers: Carol L. Prives and George F. Vande Woude, Taos, NM, 15-21 March 1999. Biochim Biophys Acta (2000) 0.75
Enzymology of homologous recombination in Saccharomyces cerevisiae. Prog Nucleic Acid Res Mol Biol (1993) 0.75