Published in Genetics on December 01, 1992
Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (1999) 19.25
Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants. Mol Cell Biol (1997) 3.60
hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6. Proc Natl Acad Sci U S A (1996) 3.60
Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae. Genetics (1994) 3.52
Microsatellite instability in yeast: dependence on the length of the microsatellite. Genetics (1997) 3.51
Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae. Mol Cell Biol (1994) 3.34
Mismatch correction acts as a barrier to homeologous recombination in Saccharomyces cerevisiae. Genetics (1995) 3.02
Gene conversions and crossing over during homologous and homeologous ectopic recombination in Saccharomyces cerevisiae. Genetics (1993) 2.83
Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene. Mol Cell Biol (1994) 2.80
Mitotic crossovers between diverged sequences are regulated by mismatch repair proteins in Saccaromyces cerevisiae. Mol Cell Biol (1996) 2.65
A phylogenomic study of the MutS family of proteins. Nucleic Acids Res (1998) 2.54
The mismatch repair system reduces meiotic homeologous recombination and stimulates recombination-dependent chromosome loss. Mol Cell Biol (1996) 2.39
The mismatch repair system contributes to meiotic sterility in an interspecific yeast hybrid. EMBO J (1996) 2.39
Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1995) 2.29
Genetic footprinting: a genomic strategy for determining a gene's function given its sequence. Proc Natl Acad Sci U S A (1995) 2.13
Dominant negative mutator mutations in the mutS gene of Escherichia coli. J Bacteriol (1994) 2.10
Requirement of mismatch repair genes MSH2 and MSH3 in the RAD1-RAD10 pathway of mitotic recombination in Saccharomyces cerevisiae. Genetics (1996) 2.09
The yeast HSM3 gene acts in one of the mismatch repair pathways. Genetics (1998) 2.04
Maintenance and integrity of the mitochondrial genome: a plethora of nuclear genes in the budding yeast. Microbiol Mol Biol Rev (2000) 2.02
Unrepaired heteroduplex DNA in Saccharomyces cerevisiae is decreased in RAD1 RAD52-independent recombination. Genetics (1994) 2.02
Sex and the single cell: meiosis in yeast. Proc Natl Acad Sci U S A (1995) 1.94
DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination. Proc Natl Acad Sci U S A (2002) 1.92
Synthetic lethality of sep1 (xrn1) ski2 and sep1 (xrn1) ski3 mutants of Saccharomyces cerevisiae is independent of killer virus and suggests a general role for these genes in translation control. Mol Cell Biol (1995) 1.88
Frameshift intermediates in homopolymer runs are removed efficiently by yeast mismatch repair proteins. Mol Cell Biol (1997) 1.87
The Saccharomyces cerevisiae Msh2 and Msh6 proteins form a complex that specifically binds to duplex oligonucleotides containing mismatched DNA base pairs. Mol Cell Biol (1996) 1.86
Substoichiometric shifting in the plant mitochondrial genome is influenced by a gene homologous to MutS. Proc Natl Acad Sci U S A (2003) 1.82
Deregulated G1-cyclin expression induces genomic instability by preventing efficient pre-RC formation. Genes Dev (2002) 1.78
Characterization of a mammalian homolog of the Escherichia coli MutY mismatch repair protein. Mol Cell Biol (1995) 1.75
Variation in efficiency of DNA mismatch repair at different sites in the yeast genome. Proc Natl Acad Sci U S A (2005) 1.71
Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology: a study with emphasis on Hürthle cell tumors. Am J Pathol (2002) 1.61
Induction of recombination between homologous and diverged DNAs by double-strand gaps and breaks and role of mismatch repair. Mol Cell Biol (1994) 1.60
The Saccharomyces cerevisiae RAD9, RAD17, RAD24 and MEC3 genes are required for tolerating irreparable, ultraviolet-induced DNA damage. Genetics (1998) 1.59
Mutation accumulation in populations of varying size: the distribution of mutational effects for fitness correlates in Caenorhabditis elegans. Genetics (2004) 1.56
Genetic and biochemical analysis of Msh2p-Msh6p: role of ATP hydrolysis and Msh2p-Msh6p subunit interactions in mismatch base pair recognition. Mol Cell Biol (1997) 1.53
Rapid kinetics of mismatch repair of heteroduplex DNA that is formed during recombination in yeast. Proc Natl Acad Sci U S A (1993) 1.53
No variation and low synonymous substitution rates in coral mtDNA despite high nuclear variation. BMC Evol Biol (2006) 1.52
Negative epistasis between natural variants of the Saccharomyces cerevisiae MLH1 and PMS1 genes results in a defect in mismatch repair. Proc Natl Acad Sci U S A (2006) 1.50
Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol (2009) 1.49
The prevention of repeat-associated deletions in Saccharomyces cerevisiae by mismatch repair depends on size and origin of deletions. Genetics (1996) 1.48
Removal of frameshift intermediates by mismatch repair proteins in Saccharomyces cerevisiae. Mol Cell Biol (1999) 1.47
Systematic mutagenesis of the Saccharomyces cerevisiae MLH1 gene reveals distinct roles for Mlh1p in meiotic crossing over and in vegetative and meiotic mismatch repair. Mol Cell Biol (2003) 1.42
Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairs. Mol Cell Biol (2007) 1.40
Multiple heterologies increase mitotic double-strand break-induced allelic gene conversion tract lengths in yeast. Genetics (1999) 1.39
The conversion gradient at HIS4 of Saccharomyces cerevisiae. I. Heteroduplex rejection and restoration of Mendelian segregation. Genetics (1999) 1.38
Mitochondrial DNA of the coral Sarcophyton glaucum contains a gene for a homologue of bacterial MutS: a possible case of gene transfer from the nucleus to the mitochondrion. J Mol Evol (1998) 1.36
Yeast as a model for human mtDNA replication. Am J Hum Genet (1999) 1.35
Saccharomyces cerevisiae Msh2p and Msh6p ATPase activities are both required during mismatch repair. Mol Cell Biol (1998) 1.33
MPH1, a yeast gene encoding a DEAH protein, plays a role in protection of the genome from spontaneous and chemically induced damage. Genetics (2000) 1.32
Repair of mtDNA in vertebrates. Am J Hum Genet (1999) 1.32
Arabidopsis MutS homologs-AtMSH2, AtMSH3, AtMSH6, and a novel AtMSH7-form three distinct protein heterodimers with different specificities for mismatched DNA. Plant Cell (2000) 1.32
Distinct roles for the Saccharomyces cerevisiae mismatch repair proteins in heteroduplex rejection, mismatch repair and nonhomologous tail removal. Genetics (2004) 1.30
The sep1 mutant of Saccharomyces cerevisiae arrests in pachytene and is deficient in meiotic recombination. Genetics (1995) 1.30
Interactions of human hMSH2 with hMSH3 and hMSH2 with hMSH6: examination of mutations found in hereditary nonpolyposis colorectal cancer. Mol Cell Biol (1998) 1.25
Evolutionary origin, diversification and specialization of eukaryotic MutS homolog mismatch repair proteins. Nucleic Acids Res (2000) 1.25
Physical interaction between components of DNA mismatch repair and nucleotide excision repair. Proc Natl Acad Sci U S A (1998) 1.24
EXO1 and MSH6 are high-copy suppressors of conditional mutations in the MSH2 mismatch repair gene of Saccharomyces cerevisiae. Genetics (2000) 1.23
Analysis of damage tolerance pathways in Saccharomyces cerevisiae: a requirement for Rev3 DNA polymerase in translesion synthesis. Mol Cell Biol (1998) 1.20
Mitochondrial DNA repair and association with aging--an update. Exp Gerontol (2010) 1.19
Genetic factors affecting the impact of DNA polymerase delta proofreading activity on mutation avoidance in yeast. Genetics (1999) 1.19
Identification of rad27 mutations that confer differential defects in mutation avoidance, repeat tract instability, and flap cleavage. Mol Cell Biol (2001) 1.19
Novel DNA mismatch-repair activity involving YB-1 in human mitochondria. DNA Repair (Amst) (2009) 1.18
DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiae. Genetics (2013) 1.17
Functional characterization of pathogenic human MSH2 missense mutations in Saccharomyces cerevisiae. Genetics (2007) 1.17
Mitochondrial genome dynamics in plants and animals: convergent gene fusions of a MutS homologue. J Mol Evol (2006) 1.15
MLH1 mutations differentially affect meiotic functions in Saccharomyces cerevisiae. Genetics (2003) 1.15
Reduction of stability of arabidopsis genomic and transgenic DNA-repeat sequences (microsatellites) by inactivation of AtMSH2 mismatch-repair function. Plant Physiol (2003) 1.11
Evolution of mutational robustness in the yeast genome: a link to essential genes and meiotic recombination hotspots. PLoS Genet (2009) 1.11
The origins and early evolution of DNA mismatch repair genes--multiple horizontal gene transfers and co-evolution. Nucleic Acids Res (2007) 1.10
Separation-of-function mutations in Saccharomyces cerevisiae MSH2 that confer mismatch repair defects but do not affect nonhomologous-tail removal during recombination. Mol Cell Biol (1999) 1.08
Recognition of DNA alterations by the mismatch repair system. Biochem J (1999) 1.08
Caenorhabditis elegans DNA mismatch repair gene msh-2 is required for microsatellite stability and maintenance of genome integrity. Proc Natl Acad Sci U S A (2002) 1.08
Mitochondrial genome maintenance in health and disease. DNA Repair (Amst) (2014) 1.08
The msh2 gene of Schizosaccharomyces pombe is involved in mismatch repair, mating-type switching, and meiotic chromosome organization. Mol Cell Biol (1999) 1.07
Mutator suppression and escape from replication error-induced extinction in yeast. PLoS Genet (2011) 1.05
Analysis of conditional mutations in the Saccharomyces cerevisiae MLH1 gene in mismatch repair and in meiotic crossing over. Genetics (2002) 1.05
Isolation and characterization of point mutations in mismatch repair genes that destabilize microsatellites in yeast. Mol Cell Biol (2001) 1.04
The REC1 gene of Ustilago maydis, which encodes a 3'-->5' exonuclease, couples DNA repair and completion of DNA synthesis to a mitotic checkpoint. Genetics (1996) 1.04
Role of DNA mismatch repair and double-strand break repair in genome stability and antifungal drug resistance in Candida albicans. Eukaryot Cell (2007) 1.03
Somatic mitochondrial mutation in gastric cancer. Am J Pathol (1995) 1.02
CYS3, a hotspot of meiotic recombination in Saccharomyces cerevisiae. Effects of heterozygosity and mismatch repair functions on gene conversion and recombination intermediates. Genetics (1999) 1.02
Analysis of microsatellite mutations in the mitochondrial DNA of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2000) 1.02
MSH2 is essential for the preservation of genome integrity and prevents homeologous recombination in the moss Physcomitrella patens. Nucleic Acids Res (2006) 1.01
A mutation of the yeast gene encoding PCNA destabilizes both microsatellite and minisatellite DNA sequences. Genetics (1999) 1.01
Characterization of the ptr6(+) gene in fission yeast: a possible involvement of a transcriptional coactivator TAF in nucleocytoplasmic transport of mRNA. Genetics (1999) 1.00
Genotype to phenotype: analyzing the effects of inherited mutations in colorectal cancer families. Mutat Res (2009) 1.00
Mismatch repair-dependent mutagenesis in nondividing cells. Proc Natl Acad Sci U S A (2012) 0.98
Microsatellite instability in Drosophila spellchecker1 (MutS homolog) mutants. Proc Natl Acad Sci U S A (1999) 0.98
Mutation avoidance and DNA repair proficiency in Ustilago maydis are differentially lost with progressive truncation of the REC1 gene product. Mol Cell Biol (1995) 0.98
Repair of heteroduplex DNA in Xenopus laevis oocytes. Genetics (1994) 0.97
The chromosome bias of misincorporations during double-strand break repair is not altered in mismatch repair-defective strains of Saccharomyces cerevisiae. Genetics (1998) 0.96
Subtle alterations in PCNA-partner interactions severely impair DNA replication and repair. PLoS Biol (2010) 0.96
A unique horizontal gene transfer event has provided the octocoral mitochondrial genome with an active mismatch repair gene that has potential for an unusual self-contained function. BMC Evol Biol (2011) 0.96
Analysis of the proteins involved in the in vivo repair of base-base mismatches and four-base loops formed during meiotic recombination in the yeast Saccharomyces cerevisiae. Genetics (2006) 0.94
Mutator dynamics in sexual and asexual experimental populations of yeast. BMC Evol Biol (2011) 0.94
Recognition of DNA insertion/deletion mismatches by an activity in Saccharomyces cerevisiae. Nucleic Acids Res (1996) 0.94
Spontaneous mutation at the mtr locus in neurospora: the molecular spectrum in wild-type and a mutator strain. Genetics (1994) 0.92
Functional studies and homology modeling of Msh2-Msh3 predict that mispair recognition involves DNA bending and strand separation. Mol Cell Biol (2010) 0.90
Preferential strand transfer and hybrid DNA formation at the recombination hotspot ade6-M26 of Schizosaccharomyces pombe. EMBO J (1994) 0.89
Rad52 function prevents chromosome loss and truncation in Candida albicans. Mol Microbiol (2011) 0.89
Transformation of intact yeast cells treated with alkali cations. J Bacteriol (1983) 100.26
The double-strand-break repair model for recombination. Cell (1983) 31.21
Transformation in yeast: development of a hybrid cloning vector and isolation of the CAN1 gene. Gene (1979) 16.95
Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast. Methods Enzymol (1991) 16.88
Escherichia coli mutator mutants deficient in methylation-instructed DNA mismatch correction. Proc Natl Acad Sci U S A (1980) 10.16
A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae. Cell (1990) 9.24
The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants. Nature (1989) 8.15
Homologous pairing and strand exchange in genetic recombination. Annu Rev Genet (1982) 6.18
Bacterial mutator genes and the control of spontaneous mutation. Annu Rev Genet (1976) 5.53
DNA mismatch correction. Annu Rev Biochem (1987) 5.33
Mutants of Diplococcus pneumoniae that lack deoxyribonucleases and other activities possibly pertinent to genetic transformation. J Bacteriol (1970) 5.04
Meiotic gene conversion mutants in Saccharomyces cerevisiae. I. Isolation and characterization of pms1-1 and pms1-2. Genetics (1985) 3.71
Induced mutagenesis in dam- mutants of Escherichia coli: a role for 6-methyladenine residues in mutation avoidance. Mol Gen Genet (1978) 3.56
Cloning and nucleotide sequence of DNA mismatch repair gene PMS1 from Saccharomyces cerevisiae: homology of PMS1 to procaryotic MutL and HexB. J Bacteriol (1989) 3.36
Heteroduplex DNA correction in Saccharomyces cerevisiae is mismatch specific and requires functional PMS genes. Mol Cell Biol (1989) 3.28
Identification of base mismatches recognized by the heteroduplex-DNA-repair system of Streptococcus pneumoniae. Cell (1982) 3.06
RADH, a gene of Saccharomyces cerevisiae encoding a putative DNA helicase involved in DNA repair. Characteristics of radH mutants and sequence of the gene. Nucleic Acids Res (1989) 2.88
Dual bidirectional promoters at the mouse dhfr locus: cloning and characterization of two mRNA classes of the divergently transcribed Rep-1 gene. Mol Cell Biol (1989) 2.66
Analysis of a gene conversion gradient at the HIS4 locus in Saccharomyces cerevisiae. Genetics (1992) 2.60
Decreasing gradients of gene conversion on both sides of the initiation site for meiotic recombination at the ARG4 locus in yeast. Genetics (1990) 2.39
The role of heteroduplex correction in gene conversion in Saccharomyces cerevisiae. Nature (1987) 2.38
Specificity of mismatch repair following transformation of Saccharomyces cerevisiae with heteroduplex plasmid DNA. Proc Natl Acad Sci U S A (1989) 2.33
Detection of heteroduplex DNA molecules among the products of Saccharomyces cerevisiae meiosis. Proc Natl Acad Sci U S A (1990) 2.26
Control of large chromosomal duplications in Escherichia coli by the mismatch repair system. Genetics (1991) 2.25
Nucleotide sequence of the Dpn II DNA methylase gene of Streptococcus pneumoniae and its relationship to the dam gene of Escherichia coli. Proc Natl Acad Sci U S A (1985) 2.19
Nucleotide sequence of the hexA gene for DNA mismatch repair in Streptococcus pneumoniae and homology of hexA to mutS of Escherichia coli and Salmonella typhimurium. J Bacteriol (1988) 2.05
Nucleotide sequence of the Salmonella typhimurium mutS gene required for mismatch repair: homology of MutS and HexA of Streptococcus pneumoniae. J Bacteriol (1988) 2.03
PIF1: a DNA helicase in yeast mitochondria. EMBO J (1991) 1.99
Cloning and sequencing of the PIF gene involved in repair and recombination of yeast mitochondrial DNA. EMBO J (1987) 1.97
Measurement of restoration and conversion: its meaning for the mismatch repair hypothesis of conversion. Cold Spring Harb Symp Quant Biol (1984) 1.93
Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase gene. J Biol Chem (1989) 1.83
Nucleotide sequence of the Streptococcus pneumoniae hexB mismatch repair gene: homology of HexB to MutL of Salmonella typhimurium and to PMS1 of Saccharomyces cerevisiae. J Bacteriol (1989) 1.67
Genetic recombination of homologous plasmids catalyzed by cell-free extracts of Saccharomyces cerevisiae. Cell (1983) 1.56
A PIF-dependent recombinogenic signal in the mitochondrial DNA of yeast. EMBO J (1985) 1.34
Integration efficiency in DNA-induced transformation of Pneumococcus. II. Genetic studies of mutant integrating all the markers with a high efficiency. Genetics (1973) 1.25
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci U S A (1998) 9.66
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet (2001) 9.34
Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell (1998) 8.31
A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair. Cell (1997) 5.49
Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae. Cell (2001) 4.96
Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants. Nat Genet (1999) 4.18
Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae. Nature (2001) 3.77
Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2. Proc Natl Acad Sci U S A (1997) 3.66
Identification and purification of a single-stranded-DNA-specific exonuclease encoded by the recJ gene of Escherichia coli. Proc Natl Acad Sci U S A (1989) 3.65
SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination. Nat Genet (2001) 3.60
Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae. Genetics (1994) 3.52
MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast. Science (1994) 3.19
Meiotic pachytene arrest in MLH1-deficient mice. Cell (1996) 3.18
Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families. Nat Med (1996) 3.07
The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations. Proc Natl Acad Sci U S A (1998) 2.77
Biochemical interaction of the Escherichia coli RecF, RecO, and RecR proteins with RecA protein and single-stranded DNA binding protein. Proc Natl Acad Sci U S A (1993) 2.77
Exonuclease I of Saccharomyces cerevisiae functions in mitotic recombination in vivo and in vitro. Mol Cell Biol (1997) 2.73
Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins. Genetics (1992) 2.50
Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repair. Mol Cell (1998) 2.49
MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice. Genes Dev (2000) 2.49
The genetic dependence of recombination in recD mutants of Escherichia coli. Genetics (1988) 2.49
The role of heteroduplex correction in gene conversion in Saccharomyces cerevisiae. Nature (1987) 2.38
Identification of mismatch repair genes and their role in the development of cancer. Curr Opin Genet Dev (1995) 2.37
Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism. Genetics (1998) 2.37
Characterization of hereditary nonpolyposis colorectal cancer families from a population-based series of cases. J Natl Cancer Inst (2000) 2.37
Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines. Cancer Res (1995) 2.35
Specificity of mismatch repair following transformation of Saccharomyces cerevisiae with heteroduplex plasmid DNA. Proc Natl Acad Sci U S A (1989) 2.33
An essential Saccharomyces cerevisiae single-stranded DNA binding protein is homologous to the large subunit of human RP-A. EMBO J (1990) 2.28
Strand exchange protein 1 from Saccharomyces cerevisiae. A novel multifunctional protein that contains DNA strand exchange and exonuclease activities. J Biol Chem (1991) 2.26
Protein interactions in genetic recombination in Escherichia coli. Interactions involving RecO and RecR overcome the inhibition of RecA by single-stranded DNA-binding protein. J Biol Chem (1994) 2.26
Genetic and physical analysis of plasmid recombination in recB recC sbcB and recB recC sbcA Escherichia coli K-12 mutants. Genetics (1989) 2.22
Characterization of DNA-binding and strand-exchange stimulation properties of y-RPA, a yeast single-strand-DNA-binding protein. J Mol Biol (1992) 2.19
Interpretation of genetic test results for hereditary nonpolyposis colorectal cancer: implications for clinical predisposition testing. JAMA (1999) 2.14
Sensitivity and specificity of clinical criteria for hereditary non-polyposis colorectal cancer associated mutations in MSH2 and MLH1. J Med Genet (2000) 2.05
Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex. Nat Genet (2000) 2.05
Repair of heteroduplex plasmid DNA after transformation into Saccharomyces cerevisiae. Mol Cell Biol (1986) 1.98
Correction of hypermutability, N-methyl-N'-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6. Cancer Res (1997) 1.96
Chloroplast DNA from higher plants replicates by both the Cairns and the rolling circle mechanism. Nature (1975) 1.94
Molecular and genetic analysis of the gene encoding the Saccharomyces cerevisiae strand exchange protein Sep1. Mol Cell Biol (1991) 1.92
Synthetic lethality of sep1 (xrn1) ski2 and sep1 (xrn1) ski3 mutants of Saccharomyces cerevisiae is independent of killer virus and suggests a general role for these genes in translation control. Mol Cell Biol (1995) 1.88
Biochemical characterization of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 complex and mispaired bases in DNA. J Biol Chem (1999) 1.84
exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair. Mol Cell Biol (2001) 1.79
Targeting of nonexpressed genes in embryonic stem cells via homologous recombination. Science (1989) 1.75
Regulation and intracellular localization of Saccharomyces cerevisiae strand exchange protein 1 (Sep1/Xrn1/Kem1), a multifunctional exonuclease. Mol Cell Biol (1995) 1.74
Saccharomyces cerevisiae MSH2, a mispaired base recognition protein, also recognizes Holliday junctions in DNA. J Mol Biol (1997) 1.71
Denaturation mapping studies on the circular chloroplast deoxyribonucleic acid from pea leaves. J Biol Chem (1975) 1.70
Purification and preliminary characterization of the Escherichia coli K-12 recF protein. J Bacteriol (1990) 1.70
MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in S. cerevisiae. Mol Cell (1999) 1.69
The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression. Cancer Res (2000) 1.68
Links between replication, recombination and genome instability in eukaryotes. Trends Biochem Sci (2000) 1.64
Identification and characterization of the Escherichia coli RecT protein, a protein encoded by the recE region that promotes renaturation of homologous single-stranded DNA. J Bacteriol (1993) 1.63
Identification of a human gene encoding a homologue of Saccharomyces cerevisiae EXO1, an exonuclease implicated in mismatch repair and recombination. Cancer Res (1998) 1.59
Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas. Hum Mol Genet (1995) 1.57
Intron splice acceptor site sequence variation in the hereditary non-polyposis colorectal cancer gene hMSH2. Eur J Cancer (1994) 1.54
Saccharomyces cerevisiae pol30 (proliferating cell nuclear antigen) mutations impair replication fidelity and mismatch repair. Mol Cell Biol (1999) 1.54
Checkpoint-dependent activation of mutagenic repair in Saccharomyces cerevisiae pol3-01 mutants. Mol Cell (2000) 1.53
Mapping of Escherichia coli chromosomal Tn5 and F insertions by pulsed field gel electrophoresis. Genetics (1988) 1.53
Purification and characterization of MSH1, a yeast mitochondrial protein that binds to DNA mismatches. J Biol Chem (1994) 1.52
Initial description of the human NLRP3 promoter. Genes Immun (2008) 1.52
Identification of a locus on chromosome 1q44 for familial cold urticaria. Am J Hum Genet (2000) 1.51
Nucleotide sequence of the Escherichia coli recJ chromosomal region and construction of recJ-overexpression plasmids. J Bacteriol (1991) 1.49
Homologous pairing and strand exchange promoted by the Escherichia coli RecT protein. Proc Natl Acad Sci U S A (1994) 1.43
DNA strand invasion promoted by Escherichia coli RecT protein. J Biol Chem (1998) 1.42
Functional analysis of human MLH1 mutations in Saccharomyces cerevisiae. Nat Genet (1998) 1.33
The sep1 mutant of Saccharomyces cerevisiae arrests in pachytene and is deficient in meiotic recombination. Genetics (1995) 1.30
Physical interaction between components of DNA mismatch repair and nucleotide excision repair. Proc Natl Acad Sci U S A (1998) 1.24
Mononucleotide microsatellite instability and germline MSH6 mutation analysis in early onset colorectal cancer. J Med Genet (1999) 1.23
Novel dominant mutations in Saccharomyces cerevisiae MSH6. Nat Genet (2000) 1.22
The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis. Cancer Res (2001) 1.21
Mutational analysis of exoribonuclease I from Saccharomyces cerevisiae. Nucleic Acids Res (1998) 1.20
Multiple functions of MutS- and MutL-related heterocomplexes. Proc Natl Acad Sci U S A (1999) 1.19
Purification and characterization of a protein from Saccharomyces cerevisiae that binds tightly to single-stranded DNA and stimulates a cognate strand exchange protein. Biochemistry (1989) 1.18
'Saccharomyces cerevisiae MSH2/6 complex interacts with Holliday junctions and facilitates their cleavage by phage resolution enzymes. J Biol Chem (1999) 1.15
Renaturation of DNA by a Saccharomyces cerevisiae protein that catalyzes homologous pairing and strand exchange. J Biol Chem (1988) 1.11
Analysis of the recE locus of Escherichia coli K-12 by use of polyclonal antibodies to exonuclease VIII. J Bacteriol (1988) 1.11
The yeast HSM3 gene is not involved in DNA mismatch repair in rapidly dividing cells. Genetics (2000) 1.09
Cloning and characterization of the human and Caenorhabditis elegans homologs of the Saccharomyces cerevisiae MSH5 gene. Genomics (1998) 1.03
The effect of DNA mismatches on the ATPase activity of MSH1, a protein in yeast mitochondria that recognizes DNA mismatches. J Biol Chem (1994) 1.02
The activity of the Saccharomyces cerevisiae strand exchange protein 1 intrinsic exonuclease during joint molecule formation. J Biol Chem (1994) 0.94
The MER3 helicase involved in meiotic crossing over is stimulated by single-stranded DNA-binding proteins and unwinds DNA in the 3' to 5' direction. J Biol Chem (2001) 0.93
Effect of terminal non-homology on intramolecular recombination of linear plasmid substrates in Escherichia coli. J Mol Biol (1992) 0.91
Accurate, high-throughput "snapshot" detection of hMLH1 mutations by two-dimensional DNA electrophoresis. Genet Test (1998) 0.84
Origin, transmission, and segregation of mitochondrial DNA dimers in mouse hybrid and cybrid cell lines. Somat Cell Mol Genet (1984) 0.81
Regulation of the reverse transcriptase of human immunodeficiency virus type 1 by dNTPs. Proc Natl Acad Sci U S A (1992) 0.79
Characterization of the interaction of Saccharomyces cerevisiae strand exchange protein 1 with DNA. J Biol Chem (1994) 0.79
Low frequency of hMSH2 mutations in Swedish HNPCC families. Int J Cancer (1997) 0.78
Guarding against mutation. Nature (2000) 0.77
Enzymology of homologous recombination in Saccharomyces cerevisiae. Prog Nucleic Acid Res Mol Biol (1993) 0.75
Saccharomyces cerevisiae proteins involved in hybrid DNA formation in vitro. Biochimie (1991) 0.75
Keystone Symposia on Molecular and Cellular Biology: 'The molecular basis of cancer'. Organizers: Carol L. Prives and George F. Vande Woude, Taos, NM, 15-21 March 1999. Biochim Biophys Acta (2000) 0.75