Published in J Cell Biol on May 15, 2000
Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation. J Cell Biol (2001) 5.03
Assembly of centrosomal proteins and microtubule organization depends on PCM-1. J Cell Biol (2002) 3.86
TPX2, A novel xenopus MAP involved in spindle pole organization. J Cell Biol (2000) 3.01
Centrosomes enhance the fidelity of cytokinesis in vertebrates and are required for cell cycle progression. J Cell Biol (2001) 2.98
TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly. Mol Biol Cell (2004) 2.65
Molecular requirements for kinetochore-associated microtubule formation in mammalian cells. Curr Biol (2006) 2.48
Dynein/dynactin regulate metaphase spindle length by targeting depolymerizing activities to spindle poles. J Cell Biol (2004) 2.46
ZW10 links mitotic checkpoint signaling to the structural kinetochore. J Cell Biol (2005) 2.36
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Integrins and cell-fate determination. J Cell Sci (2009) 1.76
Microtubule organization by the antagonistic mitotic motors kinesin-5 and kinesin-14. J Cell Biol (2010) 1.74
Cortical dynein is critical for proper spindle positioning in human cells. J Cell Biol (2012) 1.69
The drosophila protein asp is involved in microtubule organization during spindle formation and cytokinesis. J Cell Biol (2001) 1.69
Phosphorylation regulates targeting of cytoplasmic dynein to kinetochores during mitosis. J Cell Biol (2008) 1.64
NuMA-related LIN-5, ASPM-1, calmodulin and dynein promote meiotic spindle rotation independently of cortical LIN-5/GPR/Galpha. Nat Cell Biol (2009) 1.60
Spindle pole organization in Drosophila S2 cells by dynein, abnormal spindle protein (Asp), and KLP10A. Mol Biol Cell (2005) 1.57
Part of Ran is associated with AKAP450 at the centrosome: involvement in microtubule-organizing activity. Mol Biol Cell (2003) 1.57
Rae1 interaction with NuMA is required for bipolar spindle formation. Proc Natl Acad Sci U S A (2006) 1.55
A computational model predicts Xenopus meiotic spindle organization. J Cell Biol (2010) 1.53
Asymmetric friction of nonmotor MAPs can lead to their directional motion in active microtubule networks. Cell (2014) 1.51
Requirement for Nudel and dynein for assembly of the lamin B spindle matrix. Nat Cell Biol (2009) 1.49
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NuMA influences higher order chromatin organization in human mammary epithelium. Mol Biol Cell (2006) 1.14
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Cep72 regulates the localization of key centrosomal proteins and proper bipolar spindle formation. EMBO J (2009) 1.13
Force on spindle microtubule minus ends moves chromosomes. J Cell Biol (2014) 1.12
Cytoplasmic dynein nucleates microtubules to organize them into radial arrays in vivo. Mol Biol Cell (2004) 1.11
Nucleoporin translocated promoter region (Tpr) associates with dynein complex, preventing chromosome lagging formation during mitosis. J Biol Chem (2010) 1.10
Tumor antigen acrosin binding protein normalizes mitotic spindle function to promote cancer cell proliferation. Cancer Res (2010) 1.09
Poleward transport of TPX2 in the mammalian mitotic spindle requires dynein, Eg5, and microtubule flux. Mol Biol Cell (2010) 1.08
The N-terminal coiled-coil of Ndel1 is a regulated scaffold that recruits LIS1 to dynein. J Cell Biol (2011) 1.07
Human papillomavirus E7 protein deregulates mitosis via an association with nuclear mitotic apparatus protein 1. J Virol (2008) 1.06
NuMA phosphorylation by CDK1 couples mitotic progression with cortical dynein function. EMBO J (2013) 1.06
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Directly probing the mechanical properties of the spindle and its matrix. J Cell Biol (2010) 1.05
Do nuclear envelope and intranuclear proteins reorganize during mitosis to form an elastic, hydrogel-like spindle matrix? Chromosome Res (2011) 1.03
Live-cell analysis of mitotic spindle formation in taxol-treated cells. Cell Motil Cytoskeleton (2008) 1.03
Rab5 GTPase controls chromosome alignment through Lamin disassembly and relocation of the NuMA-like protein Mud to the poles during mitosis. Proc Natl Acad Sci U S A (2011) 1.01
The mammalian centrosome and its functional significance. Histochem Cell Biol (2008) 1.01
Cohesin associates with spindle poles in a mitosis-specific manner and functions in spindle assembly in vertebrate cells. Mol Biol Cell (2008) 1.00
NuMA is required for proper spindle assembly and chromosome alignment in prometaphase. BMC Res Notes (2009) 1.00
Cell cycle-dependent microtubule-based dynamic transport of cytoplasmic dynein in mammalian cells. PLoS One (2009) 1.00
NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane. EMBO J (2014) 0.98
Kaposi's sarcoma-associated herpesvirus-encoded LANA can interact with the nuclear mitotic apparatus protein to regulate genome maintenance and segregation. J Virol (2008) 0.98
The spindle assembly function of Caenorhabditis elegans katanin does not require microtubule-severing activity. Mol Biol Cell (2011) 0.98
Clinical associations and potential novel antigenic targets of autoantibodies directed against rods and rings in chronic hepatitis C infection. BMC Gastroenterol (2013) 0.97
Cyclin B degradation leads to NuMA release from dynein/dynactin and from spindle poles. EMBO Rep (2004) 0.97
Cytoplasmic dynein crosslinks and slides anti-parallel microtubules using its two motor domains. Elife (2013) 0.96
A CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer. Nat Commun (2016) 0.95
ZW10 function in mitotic checkpoint control, dynein targeting and membrane trafficking: is dynein the unifying theme? Cell Cycle (2006) 0.94
Dynein and dynactin leverage their bivalent character to form a high-affinity interaction. PLoS One (2013) 0.94
On the inscrutable role of Inscuteable: structural basis and functional implications for the competitive binding of NuMA and Inscuteable to LGN. Open Biol (2012) 0.94
Cell cycle-regulated membrane binding of NuMA contributes to efficient anaphase chromosome separation. Mol Biol Cell (2013) 0.92
Self-organization of stabilized microtubules by both spindle and midzone mechanisms in Xenopus egg cytosol. Mol Biol Cell (2013) 0.92
Inscuteable and NuMA proteins bind competitively to Leu-Gly-Asn repeat-enriched protein (LGN) during asymmetric cell divisions. Proc Natl Acad Sci U S A (2011) 0.92
Downregulation of protein 4.1R, a mature centriole protein, disrupts centrosomes, alters cell cycle progression, and perturbs mitotic spindles and anaphase. Mol Cell Biol (2008) 0.91
Geminin is partially localized to the centrosome and plays a role in proper centrosome duplication. Biol Cell (2009) 0.89
Mechanisms of plant spindle formation. Chromosome Res (2011) 0.89
Dynein/Dynactin-mediated transport of kinetochore components off kinetochores and onto spindle poles induced by nordihydroguaiaretic acid. PLoS One (2011) 0.89
Delocalization of the microtubule motor Dynein from mitotic spindles by the human papillomavirus E7 oncoprotein is not sufficient for induction of multipolar mitoses. Cancer Res (2008) 0.89
Asymmetric cell divisions in the epidermis. Int Rev Cell Mol Biol (2012) 0.88
A novel patch assembly domain in Num1 mediates dynein anchoring at the cortex during spindle positioning. J Cell Biol (2012) 0.88
NuMA is required for the selective induction of p53 target genes. Mol Cell Biol (2013) 0.88
Cep57, a NEDD1-binding pericentriolar material component, is essential for spindle pole integrity. Cell Res (2012) 0.86
Establishment and mitotic characterization of new Drosophila acentriolar cell lines from DSas-4 mutant. Biol Open (2013) 0.86
NuMA promotes homologous recombination repair by regulating the accumulation of the ISWI ATPase SNF2h at DNA breaks. Nucleic Acids Res (2014) 0.86
Mob4 plays a role in spindle focusing in Drosophila S2 cells. J Cell Sci (2008) 0.85
Function and regulation of dynein in mitotic chromosome segregation. Chromosoma (2014) 0.84
A novel isoform of MAP4 organises the paraxial microtubule array required for muscle cell differentiation. Elife (2015) 0.83
GAS41 amplification results in overexpression of a new spindle pole protein. Genes Chromosomes Cancer (2012) 0.82
Bisphenol A directly targets tubulin to disrupt spindle organization in embryonic and somatic cells. ACS Chem Biol (2008) 0.82
The Drosophila microtubule-associated protein mars stabilizes mitotic spindles by crosslinking microtubules through its N-terminal region. PLoS One (2013) 0.82
Microcephaly protein Asp focuses the minus ends of spindle microtubules at the pole and within the spindle. J Cell Biol (2015) 0.79
MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis. J Cell Sci (2012) 0.79
NuMA overexpression in epithelial ovarian cancer. PLoS One (2012) 0.79
Mitotic Diversity in Homeostatic Human Interfollicular Epidermis. Int J Mol Sci (2016) 0.79
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