Published in J Cell Biol on May 14, 2001
Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores. J Cell Biol (2003) 9.27
The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint. J Cell Biol (2003) 8.32
The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint. Genes Dev (2001) 4.82
Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases. Mol Cell Biol (2002) 4.50
Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis. Mol Biol Cell (2003) 4.28
Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle. J Cell Biol (2004) 3.49
Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets. PLoS Biol (2004) 3.39
Molecular dissection of cytokinesis by RNA interference in Drosophila cultured cells. Mol Biol Cell (2002) 3.13
Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis. J Cell Biol (2003) 3.12
Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules. J Cell Biol (2002) 3.05
The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis. Nat Rev Mol Cell Biol (2012) 2.99
Chromosomal passengers: the four-dimensional regulation of mitotic events. Chromosoma (2004) 2.94
The 3Ms of central spindle assembly: microtubules, motors and MAPs. Nat Rev Mol Cell Biol (2009) 2.88
The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment. Genes Dev (2005) 2.83
Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesis. Sci Signal (2010) 2.79
Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis. Genes Dev (2002) 2.77
CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis. J Cell Biol (2001) 2.72
Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins. Curr Opin Cell Biol (2009) 2.61
Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation. Mol Biol Cell (2002) 2.56
Differentiation of cytoplasmic and meiotic spindle assembly MCAK functions by Aurora B-dependent phosphorylation. Mol Biol Cell (2004) 2.51
Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2. J Cell Biol (2004) 2.44
Cytokinesis in eukaryotes. Microbiol Mol Biol Rev (2002) 2.43
Phosphorylation of the carboxyl terminus of inner centromere protein (INCENP) by the Aurora B Kinase stimulates Aurora B kinase activity. J Biol Chem (2002) 2.40
Pericentric heterochromatin becomes enriched with H2A.Z during early mammalian development. EMBO J (2003) 2.23
Probing the dynamics and functions of aurora B kinase in living cells during mitosis and cytokinesis. Mol Biol Cell (2002) 2.21
Condensin and Repo-Man-PP1 co-operate in the regulation of chromosome architecture during mitosis. Nat Cell Biol (2006) 2.16
The aurora kinase AIR-2 functions in the release of chromosome cohesion in Caenorhabditis elegans meiosis. J Cell Biol (2002) 2.11
In vivo dissection of the chromosome condensation machinery: reversibility of condensation distinguishes contributions of condensin and cohesin. J Cell Biol (2002) 2.05
CENP-A is required for accurate chromosome segregation and sustained kinetochore association of BubR1. Mol Cell Biol (2005) 2.00
Centromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENP. Mol Biol Cell (2006) 1.94
Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly. J Cell Biol (2008) 1.91
O-GlcNAc signalling: implications for cancer cell biology. Nat Rev Cancer (2011) 1.87
MAST/Orbit has a role in microtubule-kinetochore attachment and is essential for chromosome alignment and maintenance of spindle bipolarity. J Cell Biol (2002) 1.81
MLN8054, a small-molecule inhibitor of Aurora A, causes spindle pole and chromosome congression defects leading to aneuploidy. Mol Cell Biol (2007) 1.79
Dual role of topoisomerase II in centromere resolution and aurora B activity. PLoS Biol (2008) 1.79
A Bir1-Sli15 complex connects centromeres to microtubules and is required to sense kinetochore tension. Cell (2006) 1.79
In vivo requirements for rDNA chromosome condensation reveal two cell-cycle-regulated pathways for mitotic chromosome folding. Genes Dev (2003) 1.71
A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity. Genes Dev (2006) 1.70
Histone hyperacetylation in mitosis prevents sister chromatid separation and produces chromosome segregation defects. Mol Biol Cell (2003) 1.68
Condensin: Architect of mitotic chromosomes. Chromosome Res (2009) 1.67
A mitotic GlcNAcylation/phosphorylation signaling complex alters the posttranslational state of the cytoskeletal protein vimentin. Mol Biol Cell (2008) 1.64
Mutations in the Drosophila condensin subunit dCAP-G: defining the role of condensin for chromosome condensation in mitosis and gene expression in interphase. Genetics (2004) 1.60
Both midzone and astral microtubules are involved in the delivery of cytokinesis signals: insights from the mobility of aurora B. J Cell Biol (2002) 1.60
Notch activates cell cycle reentry and progression in quiescent cardiomyocytes. J Cell Biol (2008) 1.59
A cytokinetic function of Drosophila ORC6 protein resides in a domain distinct from its replication activity. Proc Natl Acad Sci U S A (2003) 1.55
Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line. J Cell Biol (2008) 1.54
ISWI remodeling complexes in Xenopus egg extracts: identification as major chromosomal components that are regulated by INCENP-aurora B. Mol Biol Cell (2002) 1.53
Aurora kinase inhibitors: progress towards the clinic. Invest New Drugs (2012) 1.44
Aurora kinase inhibitor ZM447439 blocks chromosome-induced spindle assembly, the completion of chromosome condensation, and the establishment of the spindle integrity checkpoint in Xenopus egg extracts. Mol Biol Cell (2004) 1.43
The condensin I subunit Barren/CAP-H is essential for the structural integrity of centromeric heterochromatin during mitosis. Mol Cell Biol (2005) 1.42
Regulation of chromatin structure by histone H3S10 phosphorylation. Chromosome Res (2006) 1.40
The chromokinesin, KLP3A, dives mitotic spindle pole separation during prometaphase and anaphase and facilitates chromatid motility. Mol Biol Cell (2003) 1.39
Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation. J Cell Biol (2011) 1.35
Contrasting roles of condensin I and condensin II in mitotic chromosome formation. J Cell Sci (2012) 1.35
Dual detection of chromosomes and microtubules by the chromosomal passenger complex drives spindle assembly. Dev Cell (2010) 1.34
Cell division: control of the chromosomal passenger complex in time and space. Chromosoma (2013) 1.34
The Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis. Mol Biol Cell (2002) 1.33
The chromosomal passenger complex activates Polo kinase at centromeres. PLoS Biol (2012) 1.33
Sds22 regulates aurora B activity and microtubule-kinetochore interactions at mitosis. J Cell Biol (2010) 1.30
The N-terminus of histone H2B, but not that of histone H3 or its phosphorylation, is essential for chromosome condensation. EMBO J (2001) 1.29
Aurora-B regulates RNA methyltransferase NSUN2. Mol Biol Cell (2007) 1.22
Recruitment of MKLP1 to the spindle midzone/midbody by INCENP is essential for midbody formation and completion of cytokinesis in human cells. Biochem J (2005) 1.20
Phosphorylation of histone H3 at serine 10 is indispensable for neoplastic cell transformation. Cancer Res (2005) 1.20
Chromatin decondensation and nuclear reprogramming by nucleoplasmin. Mol Cell Biol (2006) 1.20
The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo. J Cell Biol (2002) 1.19
The Aurora Kinase in Trypanosoma brucei plays distinctive roles in metaphase-anaphase transition and cytokinetic initiation. PLoS Pathog (2009) 1.16
Contribution of hCAP-D2, a non-SMC subunit of condensin I, to chromosome and chromosomal protein dynamics during mitosis. Mol Cell Biol (2005) 1.15
Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells. J Transl Med (2008) 1.15
Identification and dynamics of two classes of aurora-like kinases in Arabidopsis and other plants. Plant Cell (2005) 1.15
Proteomic analysis of human metaphase chromosomes reveals topoisomerase II alpha as an Aurora B substrate. Nucleic Acids Res (2002) 1.15
Taxol-stabilized microtubules can position the cytokinetic furrow in mammalian cells. Mol Biol Cell (2005) 1.14
Expression of P. falciparum var genes involves exchange of the histone variant H2A.Z at the promoter. PLoS Pathog (2011) 1.11
The kinesinlike protein Subito contributes to central spindle assembly and organization of the meiotic spindle in Drosophila oocytes. Mol Biol Cell (2005) 1.11
The C. elegans Tousled-like kinase contributes to chromosome segregation as a substrate and regulator of the Aurora B kinase. Curr Biol (2005) 1.10
Dual roles of Incenp crucial to the assembly of the acentrosomal metaphase spindle in female meiosis. Development (2008) 1.10
Phosphorylation at serine 331 is required for Aurora B activation. J Cell Biol (2011) 1.10
Zebrafish dou yan mutation causes patterning defects and extensive cell death in the retina. Dev Dyn (2007) 1.08
The chromosomal passenger complex (CPC) as a key orchestrator of orderly mitotic exit and cytokinesis. Front Cell Dev Biol (2015) 1.08
Elevated polar ejection forces stabilize kinetochore-microtubule attachments. J Cell Biol (2013) 1.08
Dissecting mitosis by RNAi in Drosophila tissue culture cells. Biol Proced Online (2003) 1.07
Mutations in the chromosomal passenger complex and the condensin complex differentially affect synaptonemal complex disassembly and metaphase I configuration in Drosophila female meiosis. Genetics (2008) 1.07
A small C-terminal sequence of Aurora B is responsible for localization and function. Mol Biol Cell (2004) 1.07
A single amino acid change converts Aurora-A into Aurora-B-like kinase in terms of partner specificity and cellular function. Proc Natl Acad Sci U S A (2009) 1.06
A dominant negative mutant of TLK1 causes chromosome missegregation and aneuploidy in normal breast epithelial cells. BMC Cell Biol (2003) 1.05
Aurora-B expression and its correlation with cell proliferation and metastasis in oral cancer. Virchows Arch (2007) 1.03
The DEAD-box RNA helicase Vasa functions in embryonic mitotic progression in the sea urchin. Development (2011) 1.02
Functional significance of the specific sites phosphorylated in desmin at cleavage furrow: Aurora-B may phosphorylate and regulate type III intermediate filaments during cytokinesis coordinatedly with Rho-kinase. Mol Biol Cell (2003) 1.01
The chromosomal passenger complex is required for meiotic acentrosomal spindle assembly and chromosome biorientation. Genetics (2012) 1.00
Haspin: a newly discovered regulator of mitotic chromosome behavior. Chromosoma (2009) 1.00
Regulation of spindle and chromatin dynamics during early and late stages of oocyte maturation by aurora kinases. Mol Hum Reprod (2008) 1.00
The localization of inner centromeric protein (INCENP) at the cleavage furrow is dependent on Kif12 and involves interactions of the N terminus of INCENP with the actin cytoskeleton. Mol Biol Cell (2007) 0.99
Cdk1 activity is required for mitotic activation of aurora A during G2/M transition of human cells. J Biol Chem (2010) 0.97
Topoisomerase IIα in chromosome instability and personalized cancer therapy. Oncogene (2014) 0.97
Nutrient-driven O-GlcNAc cycling - think globally but act locally. J Cell Sci (2014) 0.96
Drosophila Xpd regulates Cdk7 localization, mitotic kinase activity, spindle dynamics, and chromosome segregation. PLoS Genet (2010) 0.96
Centrosome amplification induced by survivin suppression enhances both chromosome instability and radiosensitivity in glioma cells. Br J Cancer (2008) 0.95
The maternal-effect gene cellular island encodes aurora B kinase and is essential for furrow formation in the early zebrafish embryo. PLoS Genet (2009) 0.95
Perturbation of Incenp function impedes anaphase chromatid movements and chromosomal passenger protein flux at centromeres. Chromosoma (2008) 0.94
Chromosome passenger complexes control anaphase duration and spindle elongation via a kinesin-5 brake. J Cell Biol (2011) 0.94
Regulation of the meiotic prophase I to metaphase I transition in mouse spermatocytes. Chromosoma (2008) 0.94
Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways. Proc Natl Acad Sci U S A (2000) 9.02
Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes. Cell (2000) 6.81
Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles. Cell (1995) 5.56
Drosophila aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis. J Cell Biol (2001) 5.34
Cell cycle-dependent specific positioning and clustering of centromeres and telomeres in fission yeast. J Cell Biol (1993) 5.11
Chromosomal passengers and the (aurora) ABCs of mitosis. Trends Cell Biol (2001) 5.09
NDC10: a gene involved in chromosome segregation in Saccharomyces cerevisiae. J Cell Biol (1993) 4.96
The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast. Genes Dev (1999) 4.69
Heterochromatic deposition of centromeric histone H3-like proteins. Proc Natl Acad Sci U S A (2000) 4.27
Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype. Curr Biol (2000) 4.27
pavarotti encodes a kinesin-like protein required to organize the central spindle and contractile ring for cytokinesis. Genes Dev (1998) 3.88
AIM-1: a mammalian midbody-associated protein required for cytokinesis. EMBO J (1998) 3.73
Immunolocalization of CENP-A suggests a distinct nucleosome structure at the inner kinetochore plate of active centromeres. Curr Biol (1997) 3.62
INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow. Curr Biol (2000) 3.55
Incenp and an aurora-like kinase form a complex essential for chromosome segregation and efficient completion of cytokinesis. Curr Biol (2000) 3.50
Chromatid segregation at anaphase requires the barren product, a novel chromosome-associated protein that interacts with Topoisomerase II. Cell (1996) 3.39
The aurora-related kinase AIR-2 recruits ZEN-4/CeMKLP1 to the mitotic spindle at metaphase and is required for cytokinesis. Curr Biol (2000) 3.23
AIR-2: An Aurora/Ipl1-related protein kinase associated with chromosomes and midbody microtubules is required for polar body extrusion and cytokinesis in Caenorhabditis elegans embryos. J Cell Biol (1998) 3.07
The A- and B-type cyclins of Drosophila are accumulated and destroyed in temporally distinct events that define separable phases of the G2-M transition. EMBO J (1990) 2.99
Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast. Genetics (1993) 2.82
Specific destruction of kinetochore protein CENP-C and disruption of cell division by herpes simplex virus immediate-early protein Vmw110. EMBO J (1999) 2.79
Aurora/Ipl1p-related kinases, a new oncogenic family of mitotic serine-threonine kinases. J Cell Sci (1999) 2.74
A dominant mutant of inner centromere protein (INCENP), a chromosomal protein, disrupts prometaphase congression and cytokinesis. J Cell Biol (1998) 2.55
Chromosomal passengers: toward an integrated view of mitosis. Chromosoma (1991) 2.54
Chromosomal proteins and cytokinesis: patterns of cleavage furrow formation and inner centromere protein positioning in mitotic heterokaryons and mid-anaphase cells. J Cell Biol (1997) 2.50
The survivin-like C. elegans BIR-1 protein acts with the Aurora-like kinase AIR-2 to affect chromosomes and the spindle midzone. Mol Cell (2000) 2.47
Injection of anticentromere antibodies in interphase disrupts events required for chromosome movement at mitosis. J Cell Biol (1990) 2.46
Sli15 associates with the ipl1 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiae. J Cell Biol (1999) 2.32
Telophase disc: a new mammalian mitotic organelle that bisects telophase cells with a possible function in cytokinesis. J Cell Sci (1991) 2.32
INCENP centromere and spindle targeting: identification of essential conserved motifs and involvement of heterochromatin protein HP1. J Cell Biol (1998) 2.23
Human survivin is a kinetochore-associated passenger protein. J Cell Biol (2000) 2.21
A role for Drosophila SMC4 in the resolution of sister chromatids in mitosis. Curr Biol (2001) 2.19
Molecular analysis of the INCENPs (inner centromere proteins): separate domains are required for association with microtubules during interphase and with the central spindle during anaphase. J Cell Biol (1993) 1.63
INCENP binds directly to tubulin and requires dynamic microtubules to target to the cleavage furrow. Exp Cell Res (2001) 1.59
Defective chromosome segregation, microtubule bundling and nuclear bridging in inner centromere protein gene (Incenp)-disrupted mice. Hum Mol Genet (1999) 1.59
Cloning, mapping, and expression of ial, a novel Drosophila member of the Ipl1/aurora mitotic control kinase family. DNA Cell Biol (1999) 1.02
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature (1994) 10.22
Structure and function in the nucleus. Science (1998) 6.26
Identification of a family of human centromere proteins using autoimmune sera from patients with scleroderma. Chromosoma (1985) 6.17
Chromosomal passengers and the (aurora) ABCs of mitosis. Trends Cell Biol (2001) 5.09
Topoisomerase II is a structural component of mitotic chromosome scaffolds. J Cell Biol (1985) 5.00
Molecular cloning of cDNA for CENP-B, the major human centromere autoantigen. J Cell Biol (1987) 4.50
CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase. EMBO J (1991) 4.22
The inner centromere protein (INCENP) antigens: movement from inner centromere to midbody during mitosis. J Cell Biol (1987) 4.05
DNA arrangement in isometric phage heads. Nature (1977) 3.98
DNA packaging by the double-stranded DNA bacteriophages. Cell (1980) 3.92
CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate. Cell (1992) 3.70
The centromere: hub of chromosomal activities. Science (1995) 3.64
Immunolocalization of CENP-A suggests a distinct nucleosome structure at the inner kinetochore plate of active centromeres. Curr Biol (1997) 3.62
INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow. Curr Biol (2000) 3.55
Induction of apoptosis by cancer chemotherapy. Exp Cell Res (2000) 3.51
Localization of topoisomerase II in mitotic chromosomes. J Cell Biol (1985) 3.35
Formation of spindle poles by dynein/dynactin-dependent transport of NuMA. J Cell Biol (2000) 3.23
ScII: an abundant chromosome scaffold protein is a member of a family of putative ATPases with an unusual predicted tertiary structure. J Cell Biol (1994) 2.98
Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution. Proc Natl Acad Sci U S A (1995) 2.89
CENP-C is required for maintaining proper kinetochore size and for a timely transition to anaphase. J Cell Biol (1994) 2.86
Two distinct pathways leading to nuclear apoptosis. J Exp Med (2000) 2.84
Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A. J Cell Sci (2001) 2.82
Specific destruction of kinetochore protein CENP-C and disruption of cell division by herpes simplex virus immediate-early protein Vmw110. EMBO J (1999) 2.79
INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis. Curr Biol (2001) 2.62
Architecture of metaphase chromosomes and chromosome scaffolds. J Cell Biol (1983) 2.61
A dominant mutant of inner centromere protein (INCENP), a chromosomal protein, disrupts prometaphase congression and cytokinesis. J Cell Biol (1998) 2.55
CENP-B: a major human centromere protein located beneath the kinetochore. J Cell Biol (1990) 2.55
Chromatin-associated protein phosphatase 1 regulates aurora-B and histone H3 phosphorylation. J Biol Chem (2001) 2.54
The kinetochore is part of the metaphase chromosome scaffold. J Cell Biol (1984) 2.51
Chromosomal proteins and cytokinesis: patterns of cleavage furrow formation and inner centromere protein positioning in mitotic heterokaryons and mid-anaphase cells. J Cell Biol (1997) 2.50
High titers of autoantibodies to topoisomerase I (Scl-70) in sera from scleroderma patients. Science (1986) 2.50
Nuclear events of apoptosis in vitro in cell-free mitotic extracts: a model system for analysis of the active phase of apoptosis. J Cell Biol (1993) 2.48
Injection of anticentromere antibodies in interphase disrupts events required for chromosome movement at mitosis. J Cell Biol (1990) 2.46
Modulation of cell death by Bcl-XL through caspase interaction. Proc Natl Acad Sci U S A (1998) 2.42
cDNA cloning of human DNA topoisomerase I: catalytic activity of a 67.7-kDa carboxyl-terminal fragment. Proc Natl Acad Sci U S A (1988) 2.38
Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle. Proc Natl Acad Sci U S A (1988) 2.34
Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis. Proc Natl Acad Sci U S A (1996) 2.31
Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells. Dev Cell (2001) 2.30
INCENP centromere and spindle targeting: identification of essential conserved motifs and involvement of heterochromatin protein HP1. J Cell Biol (1998) 2.23
Topoisomerase II: A specific marker for cell proliferation. J Cell Biol (1986) 2.22
The hBUB1 and hBUBR1 kinases sequentially assemble onto kinetochores during prophase with hBUBR1 concentrating at the kinetochore plates in mitosis. Chromosoma (1998) 2.18
Caspases and caspase inhibitors. Trends Biochem Sci (1997) 2.17
Assembly of nucleosomes: the reaction involving X. laevis nucleoplasmin. Cell (1980) 2.12
Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Res (2013) 2.12
Clinical associations of anticentromere antibodies and antibodies to topoisomerase I. A study of 355 patients. Arthritis Rheum (1988) 2.06
Three related centromere proteins are absent from the inactive centromere of a stable isodicentric chromosome. Chromosoma (1985) 2.04
Localization of CENP-E in the fibrous corona and outer plate of mammalian kinetochores from prometaphase through anaphase. Chromosoma (1997) 2.03
Identification of overlapping DNA-binding and centromere-targeting domains in the human kinetochore protein CENP-C. Mol Cell Biol (1996) 1.99
The structural organization of DNA packaged within the heads of T4 wild-type, isometric and giant bacteriophages. Cell (1978) 1.99
Molecular cloning of a human homologue of Drosophila heterochromatin protein HP1 using anti-centromere autoantibodies with anti-chromo specificity. J Cell Sci (1993) 1.90
Mitotic chromatin condensation in vitro using somatic cell extracts and nuclei with variable levels of endogenous topoisomerase II. J Cell Biol (1990) 1.88
Disruption of centromere assembly during interphase inhibits kinetochore morphogenesis and function in mitosis. Cell (1991) 1.85
Identification of a subdomain of CENP-B that is necessary and sufficient for localization to the human centromere. J Cell Biol (1992) 1.81
Structure of the human centromere at metaphase. Trends Biochem Sci (1990) 1.74
Down-regulation of HP1Hsalpha expression is associated with the metastatic phenotype in breast cancer. Cancer Res (2000) 1.66
The SMC proteins and the coming of age of the chromosome scaffold hypothesis. Bioessays (1995) 1.64
Molecular analysis of the INCENPs (inner centromere proteins): separate domains are required for association with microtubules during interphase and with the central spindle during anaphase. J Cell Biol (1993) 1.63
Characterization of neo-centromeres in marker chromosomes lacking detectable alpha-satellite DNA. Hum Mol Genet (1997) 1.60
Interphase-specific association of intrinsic centromere protein CENP-C with HDaxx, a death domain-binding protein implicated in Fas-mediated cell death. J Cell Sci (1998) 1.59
INCENP binds directly to tubulin and requires dynamic microtubules to target to the cleavage furrow. Exp Cell Res (2001) 1.59
Mast, a conserved microtubule-associated protein required for bipolar mitotic spindle organization. EMBO J (2000) 1.57
Nucleosome assembly. Nature (1980) 1.56
Cleavage furrows formed between centrosomes lacking an intervening spindle and chromosomes contain microtubule bundles, INCENP, and CHO1 but not CENP-E. Mol Biol Cell (1999) 1.51
Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes and is overexpressed in tumour cells. Chromosoma (2001) 1.50
Human CENP-H multimers colocalize with CENP-A and CENP-C at active centromere--kinetochore complexes. Hum Mol Genet (2000) 1.50
ICE-related proteases in apoptosis. Curr Opin Genet Dev (1996) 1.48
Dodeca satellite: a conserved G+C-rich satellite from the centromeric heterochromatin of Drosophila melanogaster. Proc Natl Acad Sci U S A (1992) 1.47
Mutations at the asp locus of Drosophila lead to multiple free centrosomes in syncytial embryos, but restrict centrosome duplication in larval neuroblasts. J Cell Sci (1990) 1.46
Activation of multiple interleukin-1beta converting enzyme homologues in cytosol and nuclei of HL-60 cells during etoposide-induced apoptosis. J Biol Chem (1997) 1.46
Transmission of a fully functional human neocentromere through three generations. Am J Hum Genet (1999) 1.38
Compartmentalization within the nucleus: discovery of a novel subnuclear region. J Cell Biol (1991) 1.37
The structure and dynamics of ring chromosomes in human neoplastic and non-neoplastic cells. Hum Genet (1999) 1.31
Anti-topoisomerase II recognizes meiotic chromosome cores. Chromosoma (1989) 1.28
Functional complementation of a genetic deficiency with human artificial chromosomes. Am J Hum Genet (2001) 1.26
Further evidence that CENP-C is a necessary component of active centromeres: studies of a dic(X; 15) with simultaneous immunofluorescence and FISH. Hum Mol Genet (1995) 1.26
Direct and indirect association of the small GTPase ran with nuclear pore proteins and soluble transport factors: studies in Xenopus laevis egg extracts. Mol Biol Cell (1996) 1.25
Untangling the role of DNA topoisomerase II in mitotic chromosome structure and function. Bioessays (1997) 1.24
Analysis of anticentromere autoantibodies using cloned autoantigen CENP-B. Proc Natl Acad Sci U S A (1987) 1.20
Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions. Blood (1997) 1.20
The distal half of the tail fibre of bacteriophage T4. Rigidly linked domains and cross-beta structure. J Mol Biol (1979) 1.19
Molecular mechanism in the formation of a human ring chromosome 21. Proc Natl Acad Sci U S A (1989) 1.19
In vivo phosphorylation of the 170-kDa form of eukaryotic DNA topoisomerase II. Cell cycle analysis. J Biol Chem (1989) 1.14
Partial deletion of alpha satellite DNA associated with reduced amounts of the centromere protein CENP-B in a mitotically stable human chromosome rearrangement. Mol Cell Biol (1990) 1.14
Surprising deficiency of CENP-B binding sites in African green monkey alpha-satellite DNA: implications for CENP-B function at centromeres. Mol Cell Biol (1996) 1.13
The size of the bacteriophage T4 head in solution with comments about the dimension of virus particles as visualized by electron microscopy. J Mol Biol (1978) 1.11
Caspase-mediated cleavage of DNA topoisomerase I at unconventional sites during apoptosis. J Biol Chem (1999) 1.09
Apparent caspase independence of programmed cell death in Dictyostelium. Curr Biol (1998) 1.09
Comparison of paclitaxel-, 5-fluoro-2'-deoxyuridine-, and epidermal growth factor (EGF)-induced apoptosis. Evidence for EGF-induced anoikis. J Biol Chem (1999) 1.08
DNA topoisomerase IIalpha interacts with CAD nuclease and is involved in chromatin condensation during apoptotic execution. Curr Biol (2000) 1.08
Mutations in new cell cycle genes that fail to complement a multiply mutant third chromosome of Drosophila. Genetics (1996) 1.08
A dynamic connection between centromeres and ND10 proteins. J Cell Sci (1999) 1.07
Mammalian centromeres: DNA sequence, protein composition, and role in cell cycle progression. Exp Cell Res (1999) 1.06
CAD/DFF40 nuclease is dispensable for high molecular weight DNA cleavage and stage I chromatin condensation in apoptosis. J Biol Chem (2001) 1.05
Mapping DNA within the mammalian kinetochore. J Cell Biol (1993) 1.03
Transition from caspase-dependent to caspase-independent mechanisms at the onset of apoptotic execution. J Cell Biol (1998) 1.03
Centromeres: old tales and new tools. FEBS Lett (2008) 1.03
Biophysical studies of reovirus type 3. IV. Low-angle x-ray diffraction studies. Virology (1981) 1.02