Published in J Cell Biol on March 01, 1978
Filament organization revealed in platinum replicas of freeze-dried cytoskeletons. J Cell Biol (1980) 5.61
Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells. J Cell Biol (1982) 3.85
Distribution of a matrix component of the midbody during the cell cycle in Chinese hamster ovary cells. J Cell Biol (1988) 2.67
High molecular weight microtubule-associated proteins are preferentially associated with dendritic microtubules in brain. Proc Natl Acad Sci U S A (1981) 2.60
Distribution of microtubule organizing centers in migrating sheets of endothelial cells. J Cell Biol (1981) 2.51
Studies on the expression of the microtubule-associated protein, tau, during mouse brain development, with newly isolated complementary DNA probes. J Cell Biol (1984) 2.05
Microtubule-associated proteins: a monoclonal antibody to MAP2 binds to differentiated neurons. Proc Natl Acad Sci U S A (1980) 2.03
Association of microtubule-associated protein 2 (MAP 2) with microtubules and intermediate filaments in cultured brain cells. J Cell Biol (1983) 1.93
Immunofluorescence localization of HeLa cell microtubule-associated proteins on microtubules in vitro and in vivo. J Cell Biol (1980) 1.87
Involvement of microtubules and 10-nm filaments in the movement and positioning of nuclei in syncytia. J Cell Biol (1979) 1.78
Widespread distribution of a 210,000 mol wt microtubule-associated protein in cells and tissues of primates. J Cell Biol (1980) 1.74
Microinjection of fluorescent tubulin into dividing sea urchin cells. J Cell Biol (1983) 1.67
Mitosis in a cell with multiple centrioles. J Cell Biol (1982) 1.63
A microtubule-associated protein antigen unique to mitotic spindle microtubules in PtK1 cells. J Cell Biol (1983) 1.62
Phosphorylation of microtubule-associated proteins by a Ca2+/calmodulin-dependent protein kinase. J Cell Biol (1984) 1.61
A microtubule-associated protein in Drosophila melanogaster: identification, characterization, and isolation of coding sequences. J Cell Biol (1986) 1.59
Functional implications of cold-stable microtubules in kinetochore fibers of insect spermatocytes during anaphase. J Cell Biol (1980) 1.56
MAP 4: occurrence in mouse tissues. J Cell Biol (1984) 1.48
High molecular weight polypeptides (270,000-340,000) from cultured cells are related to hog brain microtubule-associated proteins but copurify with intermediate filaments. Proc Natl Acad Sci U S A (1980) 1.38
Structure and composition of the cytoskeleton of nucleated erythrocytes I. The presence of microtubule-associated protein 2 in the marginal band. J Cell Biol (1980) 1.32
Microtubule-associated proteins of HeLa cells: heat stability of the 200,000 mol wt HeLa MAPs and detection of the presence of MAP-2 in HeLa cell extracts and cycled microtubules. J Cell Biol (1982) 1.30
Microtubule-associated proteins of neurons. J Cell Biol (1983) 1.28
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A marginal band-associated protein has properties of both microtubule- and microfilament-associated proteins. J Cell Biol (1989) 1.09
Immunoelectron microscopic localization of the 210,000-mol wt microtubule-associated protein in cultured cells of primates. J Cell Biol (1981) 1.08
A functional in vitro model for studies of intracellular motility in digitonin-permeabilized erythrophores. J Cell Biol (1982) 1.08
MAP 4: a microtubule-associated protein specific for a subset of tissue microtubules. J Cell Biol (1984) 1.02
Widespread occurrence of polypeptides related to neurotubule-associated proteins (MAP-1 and MAP-2) in non-neuronal cells and tissues. EMBO J (1984) 1.02
Analyzing the components of microtubules: antibodies against chartins, associated proteins from cultured cells. Proc Natl Acad Sci U S A (1985) 1.01
Role of the cytoskeleton in the formation, stabilization, and removal of acetylcholine receptor clusters in cultured muscle cells. J Cell Biol (1984) 0.98
Differential phosphorylation of MAP-2 stimulated by calcium-calmodulin and cyclic AMP. Mol Cell Biol (1984) 0.92
Microtubule-associated proteins and in vitro astrocyte differentiation. J Cell Biol (1985) 0.91
Effect upon mitogenic stimulation of calcium-dependent phosphorylation of cytoskeleton-associated 350,000- and 80,000-mol-wt polypeptides in quiescent 3Y1 cells. J Cell Biol (1985) 0.90
Microtubules and microfilaments during cell spreading and colony formation in PK 15 epithelial cells. Proc Natl Acad Sci U S A (1981) 0.83
Cytoplasmic microtubule assembly-disassembly from endogenous tubulin in a Brij-lysed cell model. J Cell Biol (1983) 0.82
Cytomatrix in chromatophores. J Cell Biol (1984) 0.80
Expression of microtubule networks in normal cells, transformed cells, and their hybrids. J Cell Biol (1979) 0.75
Quantitative analysis of tau-microtubule interaction using FRET. Int J Mol Sci (2014) 0.75
Microtubule assembly in the absence of added nucleotides. Proc Natl Acad Sci U S A (1973) 18.46
A protein factor essential for microtubule assembly. Proc Natl Acad Sci U S A (1975) 15.35
Association of high-molecular-weight proteins with microtubules and their role in microtubule assembly in vitro. Proc Natl Acad Sci U S A (1975) 6.35
Physical and chemical properties of purified tau factor and the role of tau in microtubule assembly. J Mol Biol (1977) 4.60
Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin. J Mol Biol (1977) 4.42
Microtubule-associated proteins and the stimulation of tubulin assembly in vitro. Biochemistry (1976) 4.12
Microtubules from mammalian brain: some properties of their depolymerization products and a proposed mechanism of assembly and disassembly. Proc Natl Acad Sci U S A (1974) 3.59
Properties of the depolymerization products of microtubules from mammalian brain. Biochemistry (1974) 3.58
Visualization of a system of filaments 7-10 nm thick in cultured cells of an epithelioid line (Pt K2) by immunofluorescence microscopy. Proc Natl Acad Sci U S A (1977) 3.52
Immunoflourescent staining of cytoplasmic and spindle microtubules in mouse fibroblasts with antibody to tau protein. Proc Natl Acad Sci U S A (1977) 2.41
Localization of the neurofilament protein in neuroblastoma cells by immunofluorescent staining. Proc Natl Acad Sci U S A (1976) 2.17
Identity and polymerization-stimulatory activity of the nontubulin proteins associated with microtubules. Biochemistry (1977) 2.07
The reconstitution of microtubules from purified calf brain tubulin. Biochemistry (1975) 2.02
Polycation-induced assembly of purified tubulin. Proc Natl Acad Sci U S A (1976) 1.99
Tubulin requires tau for growth onto microtubule initiating sites. Proc Natl Acad Sci U S A (1976) 1.91
Brain tubulin polymerization in the absence of "microtubule-associated proteins". Proc Natl Acad Sci U S A (1976) 1.87
Tubulin requires an accessory protein for self assembly in microtubules. Nature (1975) 1.73
Reversible in vitro polymerization of tubulin from a cultured cell line (rat glial cell clone C6). Proc Natl Acad Sci U S A (1976) 1.25
Spindle birefringence of isolated mitotic apparatus: further evidence for two birefringent spindle components. J Cell Sci (1976) 1.24
In vitro assembly of pure tubulin into microtubules in the absence of microtubule-associated proteins and glycerol. Proc Natl Acad Sci U S A (1977) 1.19
Antisera against electrophoretically purified tubulin stimulate colchicine-binding activity. Proc Natl Acad Sci U S A (1976) 1.07
Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. J Biol Chem (1977) 72.51
Cyclin is degraded by the ubiquitin pathway. Nature (1991) 17.93
Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes. Cell (1980) 17.55
A protein factor essential for microtubule assembly. Proc Natl Acad Sci U S A (1975) 15.35
High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment. Nucleic Acids Res (1984) 10.40
Cyclin synthesis drives the early embryonic cell cycle. Nature (1989) 9.73
The role of cyclin synthesis and degradation in the control of maturation promoting factor activity. Nature (1989) 8.69
How proteolysis drives the cell cycle. Science (1996) 8.59
A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell (1995) 8.34
Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p. Genes Dev (1996) 8.28
CENP-E is a plus end-directed kinetochore motor required for metaphase chromosome alignment. Cell (1997) 8.08
The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly. Cell (1999) 8.07
Cyclin activation of p34cdc2. Cell (1990) 6.87
Geminin, an inhibitor of DNA replication, is degraded during mitosis. Cell (1998) 6.69
The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1. Genes Dev (2000) 6.43
Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science (2003) 6.35
cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2. Cell (1991) 6.32
ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. Neuron (1997) 6.16
Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis. Science (1999) 6.07
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron (1995) 6.03
The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation. Genes Dev (1998) 5.96
Bioenergetics and kinetics of microtubule and actin filament assembly-disassembly. Int Rev Cytol (1982) 5.93
Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins. Nature (1986) 5.90
Dominoes and clocks: the union of two views of the cell cycle. Science (1989) 5.74
Nucleotide and corresponding amino acid sequences encoded by alpha and beta tubulin mRNAs. Nature (1981) 5.65
Filament organization revealed in platinum replicas of freeze-dried cytoskeletons. J Cell Biol (1980) 5.61
CENP-E is a putative kinetochore motor that accumulates just before mitosis. Nature (1992) 5.54
Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism. Science (1997) 5.40
Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1. Mol Cell (1998) 5.28
Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1. Science (1998) 5.23
Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau. Mol Biol Cell (1992) 5.11
A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly. Cell (1996) 5.10
Mitosis in transition. Cell (1994) 5.03
Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein. J Cell Biol (1991) 5.02
Polewards chromosome movement driven by microtubule depolymerization in vitro. Nature (1988) 4.97
A structural scaffolding of intermediate filaments in health and disease. Science (1998) 4.70
Physical and chemical properties of purified tau factor and the role of tau in microtubule assembly. J Mol Biol (1977) 4.60
Molecular cloning of cDNA for CENP-B, the major human centromere autoantigen. J Cell Biol (1987) 4.50
Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin. J Mol Biol (1977) 4.42
Implications of treadmilling for the stability and polarity of actin and tubulin polymers in vivo. J Cell Biol (1980) 4.39
Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation. Nature (2007) 4.31
Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. Cell (1991) 4.31
Dual inhibition of sister chromatid separation at metaphase. Cell (2001) 4.23
CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase. EMBO J (1991) 4.22
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Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. Science (1997) 4.19
Role of phosphorylation in p34cdc2 activation: identification of an activating kinase. Mol Biol Cell (1992) 4.17
Properties of Saccharomyces cerevisiae wee1 and its differential regulation of p34CDC28 in response to G1 and G2 cyclins. EMBO J (1993) 4.10
CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint. Nat Cell Biol (2000) 3.96
Waiting for anaphase: Mad2 and the spindle assembly checkpoint. Cell (2000) 3.88
Gamma-tubulin is a centrosomal protein required for cell cycle-dependent microtubule nucleation. Nature (1992) 3.87
Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells. J Cell Biol (1982) 3.85
Unpolymerized tubulin modulates the level of tubulin mRNAs. Cell (1981) 3.78
Identification of cell cycle-regulated phosphorylation sites on nuclear lamin C. Cell (1990) 3.67
Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts. Mol Cell (2000) 3.65
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Autoregulated instability of beta-tubulin mRNAs by recognition of the nascent amino terminus of beta-tubulin. Nature (1988) 3.57
Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. Nature (1995) 3.56
Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate. J Cell Biol (2000) 3.39
Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity. Proc Natl Acad Sci U S A (1994) 3.36
A microtubule-associated protein from Xenopus eggs that specifically promotes assembly at the plus-end. J Cell Biol (1987) 3.30
The expression and posttranslational modification of a neuron-specific beta-tubulin isotype during chick embryogenesis. Cell Motil Cytoskeleton (1990) 3.25
Formation of spindle poles by dynein/dynactin-dependent transport of NuMA. J Cell Biol (2000) 3.23
Spontaneous formation of nucleus-like structures around bacteriophage DNA microinjected into Xenopus eggs. Cell (1983) 3.21
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint. Cell (2001) 3.16
Nerve growth factor-induced neurite outgrowth in PC12 cells involves the coordinate induction of microtubule assembly and assembly-promoting factors. J Cell Biol (1985) 3.16
Evidence for instability of mRNAs containing AUUUA motifs mediated through translation-dependent assembly of a > 20S degradation complex. Genes Dev (1992) 3.14
Molecular biology and genetics of tubulin. Annu Rev Biochem (1985) 3.14
Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains. Mol Cell Biol (1989) 3.09
Mutagenic analysis of the destruction signal of mitotic cyclins and structural characterization of ubiquitinated intermediates. Mol Biol Cell (1996) 2.99
Mitotic inactivation of a human SWI/SNF chromatin remodeling complex. Genes Dev (1998) 2.93
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Tau protein function in living cells. J Cell Biol (1986) 2.89
An antisense mRNA directs the covalent modification of the transcript encoding fibroblast growth factor in Xenopus oocytes. Cell (1989) 2.88
Tau protein binds to microtubules through a flexible array of distributed weak sites. J Cell Biol (1991) 2.85
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Two distinct classes of keratin genes and their evolutionary significance. Cell (1981) 2.84
Peptide mapping in one dimension by limited proteolysis of sodium dodecyl sulfate-solubilized proteins. Methods Enzymol (1983) 2.82
Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons. Nat Neurosci (1999) 2.81
LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome. Neuron (2000) 2.78
The microtubule-dependent motor centromere-associated protein E (CENP-E) is an integral component of kinetochore corona fibers that link centromeres to spindle microtubules. J Cell Biol (1997) 2.77
Ocular retardation mouse caused by Chx10 homeobox null allele: impaired retinal progenitor proliferation and bipolar cell differentiation. Nat Genet (1996) 2.75
Properties of the kinetochore in vitro. I. Microtubule nucleation and tubulin binding. J Cell Biol (1985) 2.75
INH, a negative regulator of MPF, is a form of protein phosphatase 2A. Cell (1991) 2.73
Regulation of the cell cycle during early Xenopus development. Cell (1984) 2.73
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