Published in J Exp Med on June 01, 1975
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Subclass restriction of murine antibodies. II. The IgG plaque-forming cell response to thymus-independent type 1 and type 2 antigens in normal mice and mice expressing an X-linked immunodeficiency. J Exp Med (1980) 3.13
Idiotypic analysis of lymphocytes in vitro. I. Specificity and heterogeneity of B and T lymphocytes reactive with anti-idiotypic antibody. J Exp Med (1976) 2.05
Subclass restriction of murine antibodies. III. Antigens that stimulate IgG3 in mice stimulate IgG2c in rats. J Exp Med (1980) 1.34
Distinct functions of monoclonal IgG antibody depend on antigen-site specificities. J Exp Med (1979) 1.12
Antipolysaccharide antibodies of restricted heterogeneity secreted by a single lymph node. J Exp Med (1976) 0.95
Clonal nature of the immune response. II. The effect of immunization on clonal commitment. J Exp Med (1980) 0.92
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Monoclonal antibodies against Enterocytozoon bieneusi of human origin. Clin Diagn Lab Immunol (2005) 0.90
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Improved diagnostic accuracy using monoclonal antibody group A streptococcal carbohydrate. J Clin Microbiol (1980) 0.79
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Studies on the chemical structure of the streptococcal cell wall. I. The identification of a mucopeptide in the cell walls of groups A and A-variant streptococci. J Exp Med (1961) 10.89
Variation in the group-specific carbohydrate of group A streptococci. I. Immunochemical studies on the carbohydrates of variant strains. J Exp Med (1955) 10.31
Genetic control of specific immune responses. Adv Immunol (1969) 8.81
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Regulatory effect of antibody on the immune response. Adv Immunol (1968) 6.03
Further studies on the chemical basis for serological specificity of Group A streptococcal carbohydrate. J Exp Med (1958) 4.90
Genetics of the antibody response to dextran in mice. Science (1972) 4.37
Affinity labeling of a phosphorylcholine binding mouse myeloma protein. Biochemistry (1972) 4.26
Plaque forming cells: methodology and theory. Transplant Rev (1974) 3.92
Specific suppression of the antibody response by antibodies to receptors. Proc Natl Acad Sci U S A (1972) 3.02
Studies on the regulation of avidity at the level of the single antibody-forming cell. The effect of antigen dose and time after immunization. J Exp Med (1970) 2.74
Effect of the number of haptens coupled to each erythrocyte on haemolytic plaque formation. Immunology (1969) 2.71
The search for antibodies with molecular uniformity. Adv Immunol (1970) 2.61
Idiotypic identity of antibodies to streptococcal carbohydrate in inbred mice. Eur J Immunol (1972) 2.52
Selective roles of thymus-derived lymphocytes in the antibody response. I. Differential suppressive effect of carrier-primed T cells on hapten-specific IgM and IgG antibody responses. J Exp Med (1974) 2.50
Receptors on immunocompetent cells. V. Cellular correlates of the "maturation" of the immune response. J Exp Med (1972) 2.03
Clonal nature of the immune response to phosphorylcholine. IV. Idiotypic uniformity of binding site-associated antigenic determinants among mouse antiphosphorylcholine antibodies. J Exp Med (1974) 2.02
Clonal nature of the immune response to phosphorylcholine. II. Idiotypic specificity and binding characteristics of anti-phosphorylcholine antibodies. J Immunol (1974) 1.95
Selection of a single antibody-forming cell clone and its propagation in syngeneic mice. Proc Natl Acad Sci U S A (1970) 1.89
Clonal nature of the immune response to phosphorylcholine. I. Specificity, class, and idiotype of phosphorylcholine-binding receptors on lymphoid cells. J Exp Med (1974) 1.85
Cellular events in the induction and loss of tolerance to pneumococcal polysaccharides. Transplant Rev (1972) 1.85
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Differences in antigen handling by peritoneal macrophages from the Biozzi high and low responder lines of mice. Eur J Immunol (1974) 1.54
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The use of concanavalin A for distinguishing IgM from IgG antibody-producing cells. J Immunol (1969) 1.30
Analogies between lymphocyte receptors and the resulting humoral antibodies. Transplant Rev (1970) 1.29
Streptococcal group A carbohydrate antibodies in mice: evidence for strain differences in magnitude and restriction of the response, and for thymus dependence. Eur J Immunol (1972) 1.24
Adsorption of 3H-fatty acid esters of streptococcal groups A and E cell wall polysaccharide antigens by red blood cells and their effect on hemagglutination. J Bacteriol (1969) 1.20
Use of 2-mercaptoethanol for distinguishing between IgM and IgG antibody-producing cells of mice immunized with bovine globulin. J Immunol (1972) 1.16
Dominance of a cell clone forming antibody to DNP. Nature (1972) 1.16
Differential induction of anti-trinitrophenyl plaque-forming cell responses to lightly and heavily conjugated trinitrophenylated heterologous and autologous erythrocytes in mice. Eur J Immunol (1974) 1.11
Amino-acid sequence of an allotype b4 light chain from a rabbit antibody to streptococcal carbohydrate. Proc Natl Acad Sci U S A (1974) 1.07
Homogeneous antibodies: induction and value as probe for the antibody problem. Curr Top Microbiol Immunol (1974) 1.04
Genetics of restricted antibodies to streptococcal group polysaccharides in mice. I. Strain differences of isoelectric focusing spectra of group A hyperimmune antisera. J Exp Med (1974) 1.03
Mouse strain-specific idiotypy and interstrain idiotypic cross-reactions. J Immunol (1974) 1.03
In vitro antibody response of primed rabbit peripheral blood lymphocytes to group A variant streptococcal polysaccharide. Eur J Immunol (1974) 1.02
Immune response to liposomal model membranes: restricted IgM and IgG anti-dinitrophenyl antibodies produced in guinea pigs. J Immunol (1975) 1.00
Mouse antibodies to group A streptococcal carbohydrate; use of idiotypy to detect inbred strain specificity and to monitor spleen cell transfer in syngenetic mice. J Immunol (1972) 1.00
Homogeneous elicited antibodies: induction, characterization, isolation, and structure. Ann N Y Acad Sci (1971) 0.95
Amino acid sequence of rabbit pneumococcal antibody. I. Light-chain cysteine-containing peptides. Biochemistry (1972) 0.93
Equine anti-hapten antibody. VII. Anti-lactoside antibody induced by a bacterial vaccine. Immunochemistry (1973) 0.92
Analysis of affinity of monoclonal antibody responses by inhibition of plaque-forming cells. Eur J Immunol (1974) 0.90
Linkage and rearrangement of genes encoding mouse immunoglobulin heavy chains. Nature (1974) 0.90
Evolution of the immune response to type 3 and 8 pneumococcal polysaccharides. J Immunol (1973) 0.87
Maturation of the immune response to type three pneumococcal polysaccharide. Immunochemistry (1972) 0.84
The affinity and temporal variation of isoelectric fractions of rabbit anti-lactose antibody. Biochemistry (1973) 0.82
Immunological maturation. Preferential proliferation of high-affinity precursor cells. J Exp Med (1973) 0.82
Antiphosphocholine antibodies found in normal mouse serum are protective against intravenous infection with type 3 streptococcus pneumoniae. J Exp Med (1981) 6.45
Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae. Infect Immun (1989) 5.23
Subclass restriction of murine anti-carbohydrate antibodies. J Immunol (1978) 4.99
Use of insertional inactivation to facilitate studies of biological properties of pneumococcal surface protein A (PspA). J Exp Med (1987) 3.94
Pneumococcal surface protein A (PspA) is serologically highly variable and is expressed by all clinically important capsular serotypes of Streptococcus pneumoniae. Infect Immun (1990) 3.66
Geographic distribution of penicillin-resistant clones of Streptococcus pneumoniae: characterization by penicillin-binding protein profile, surface protein A typing, and multilocus enzyme analysis. Clin Infect Dis (1992) 3.52
Pneumococcal surface protein A inhibits complement activation by Streptococcus pneumoniae. Infect Immun (1999) 3.39
Diversity of PspA: mosaic genes and evidence for past recombination in Streptococcus pneumoniae. Infect Immun (2000) 3.30
Prevention of rejection of murine islet allografts by pretreatment with anti-dendritic cell antibody. Proc Natl Acad Sci U S A (1984) 3.14
Subclass restriction of murine antibodies. II. The IgG plaque-forming cell response to thymus-independent type 1 and type 2 antigens in normal mice and mice expressing an X-linked immunodeficiency. J Exp Med (1980) 3.13
Structural properties and evolutionary relationships of PspA, a surface protein of Streptococcus pneumoniae, as revealed by sequence analysis. J Bacteriol (1992) 3.05
Monoclonal antibodies against protease-sensitive pneumococcal antigens can protect mice from fatal infection with Streptococcus pneumoniae. J Exp Med (1984) 3.02
PspA, a surface protein of Streptococcus pneumoniae, is capable of eliciting protection against pneumococci of more than one capsular type. Infect Immun (1991) 2.96
The pspC gene of Streptococcus pneumoniae encodes a polymorphic protein, PspC, which elicits cross-reactive antibodies to PspA and provides immunity to pneumococcal bacteremia. Infect Immun (1999) 2.94
Receptors on immunocompetent cells. II. Specificity and nature of receptors on dinitrophenylated guinea pig albumin- 125 I-binding lymphocytes of normal guinea pigs. J Exp Med (1971) 2.92
Effect of teichoic acid on resistance to the membrane-lytic agent of Streptococcus zymogenes. J Bacteriol (1966) 2.87
Transformation of encapsulated Streptococcus pneumoniae. J Bacteriol (1986) 2.82
Truncated forms of PspA that are secreted from Streptococcus pneumoniae and their use in functional studies and cloning of the pspA gene. J Bacteriol (1992) 2.80
Anti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae. J Exp Med (1982) 2.79
Immunization of mice with combinations of pneumococcal virulence proteins elicits enhanced protection against challenge with Streptococcus pneumoniae. Infect Immun (2000) 2.64
Intranasal immunization of mice with PspA (pneumococcal surface protein A) can prevent intranasal carriage, pulmonary infection, and sepsis with Streptococcus pneumoniae. J Infect Dis (1997) 2.50
Establishment of a Streptococcus pneumoniae nasopharyngeal colonization model in adult mice. Microb Pathog (1997) 2.41
Anti-DNA autoantibodies in (NZB X NZW)F1 mice are clonally heterogeneous, but the majority share a common idiotype. J Immunol (1982) 2.25
Depletion of antibody-forming cells and their precursors from complex lymphoid cell populations. J Immunol (1972) 2.24
Localization of protection-eliciting epitopes on PspA of Streptococcus pneumoniae between amino acid residues 192 and 260. Microb Pathog (1994) 2.20
Protection of mice from infection with Streptococcus pneumoniae by anti-phosphocholine antibody. Infect Immun (1982) 2.19
Mouse Igg3 antibodies are highly protective against infection with Streptococcus pneumoniae. Nature (1981) 2.16
Natural development of antibodies to pneumococcal surface protein A, pneumococcal surface adhesin A, and pneumolysin in relation to pneumococcal carriage and acute otitis media. J Infect Dis (2000) 2.11
Syrinx 2A: an improved lambda phage vector designed for screening DNA libraries by recombination in vivo. Proc Natl Acad Sci U S A (1987) 2.11
Receptors on immunocompetent cells. 3. Specificity and nature of receptors on dinitrophenylated guinea pig albumin- 125 I-binding cells of immunized guinea pigs. J Exp Med (1971) 2.11
Immunization of healthy adults with a single recombinant pneumococcal surface protein A (PspA) variant stimulates broadly cross-reactive antibodies to heterologous PspA molecules. Vaccine (2000) 2.07
Receptors on immunocompetent cells. V. Cellular correlates of the "maturation" of the immune response. J Exp Med (1972) 2.03
Clonal nature of the immune response to phosphorylcholine. IV. Idiotypic uniformity of binding site-associated antigenic determinants among mouse antiphosphorylcholine antibodies. J Exp Med (1974) 2.02
A pneumolysin-negative mutant of Streptococcus pneumoniae causes chronic bacteremia rather than acute sepsis in mice. Infect Immun (1995) 2.01
Competition among Streptococcus pneumoniae for intranasal colonization in a mouse model. Vaccine (2000) 2.00
Truncated Streptococcus pneumoniae PspA molecules elicit cross-protective immunity against pneumococcal challenge in mice. J Infect Dis (1996) 1.97
Clonal nature of the immune response to phosphorylcholine. II. Idiotypic specificity and binding characteristics of anti-phosphorylcholine antibodies. J Immunol (1974) 1.95
Genetic disruption of the murine complement C3 promoter region generates deficient mice with extrahepatic expression of C3 mRNA. Immunopharmacology (1999) 1.94
Amino acid sequence of homogeneous antibodies to dextran and DNA rearrangements in heavy chain V-region gene segments. Nature (1980) 1.94
Clonal nature of the immune response to phosphorylcholine. I. Specificity, class, and idiotype of phosphorylcholine-binding receptors on lymphoid cells. J Exp Med (1974) 1.85
Prolongation of islet allograft survival following in vitro culture (24 degrees C) and a single injection of ALS. Science (1979) 1.82
IgG anti-DNA autoantibodies within an individual autoimmune mouse are the products of clonal selection. J Immunol (1989) 1.81
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Intranasal vaccination with pneumococcal surface protein A and interleukin-12 augments antibody-mediated opsonization and protective immunity against Streptococcus pneumoniae infection. Infect Immun (2001) 1.74
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Receptors on immunocompetent cells. I. Receptor specificity of cells participating in a cellular immune response. Cell Immunol (1970) 1.70
The IS1167 insertion sequence is a phylogenetically informative marker among isolates of serotype 6B Streptococcus pneumoniae. J Mol Evol (1998) 1.68
Differences in virulence for mice among Streptococcus pneumoniae strains of capsular types 2, 3, 4, 5, and 6 are not attributable to differences in pneumolysin production. Infect Immun (1997) 1.67
Analysis of a surface protein of Streptococcus pneumoniae recognised by protective monoclonal antibodies. Microb Pathog (1986) 1.64
Human C-reactive protein is protective against fatal Streptococcus pneumoniae infection in transgenic mice. J Immunol (1995) 1.61
Role of complement in C-reactive-protein-mediated protection of mice from Streptococcus pneumoniae. Infect Immun (1996) 1.60
Protective humoral response against pneumococcal infection in mice elicited by recombinant bacille Calmette-Guérin vaccines expressing pneumococcal surface protein A. J Exp Med (1994) 1.55
The hemolytic and complement-activating properties of pneumolysin do not contribute individually to virulence in a pneumococcal bacteremia model. Microb Pathog (1997) 1.55
Immunoglobulin subclass-specific immunodeficiency in mice with an X-linked B-lymphocyte defect. J Exp Med (1979) 1.54
Variation in the molecular weight of PspA (pneumococcal surface protein A) among Streptococcus pneumoniae. Microb Pathog (1990) 1.53
L2C Guinea pig lymphatic leukemia: a "B" cell leukemia. Blood (1972) 1.52
Cross-reactions of the group-specific polysaccharides of streptococcal groups B and G in anti-pneumococcal sera with especial reference to type 23 and its determinants. J Immunol (1967) 1.51
Electrophoretic analysis of polypeptide chains isolated from antibodies in the serum of immunized rabbits. J Immunol (1967) 1.51
Genetic control of the susceptibility to pneumococcal infection. Curr Top Microbiol Immunol (1986) 1.50
A 43-kilodalton pneumococcal surface protein, PspA: isolation, protective abilities, and structural analysis of the amino-terminal sequence. Infect Immun (1991) 1.48
Analysis of pneumococcal PspA microheterogeneity in SDS polyacrylamide gels and the association of PspA with the cell membrane. Microb Pathog (1992) 1.48
Monoclonal antibodies to Salmonella lipopolysaccharide: anti-O-polysaccharide antibodies protect C3H mice against challenge with virulent Salmonella typhimurium. J Immunol (1984) 1.48
Role of T lymphocytes in the humoral immune response. I. Proliferation of B lymphocytes in thymus-deprived mice. J Immunol (1974) 1.46
Structural correlates of cross-reactive and individual idiotypic determinants on murine antibodies to alpha-(1 leads to 3) dextran. J Exp Med (1980) 1.46
Epidemiological studies of Streptococcus pneumoniae in infants: development of antibody to phosphocholine. J Clin Microbiol (1983) 1.45
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A 'safe-site' for Salmonella typhimurium is within splenic cells during the early phase of infection in mice. Microb Pathog (1991) 1.35
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A live recombinant avirulent oral Salmonella vaccine expressing pneumococcal surface protein A induces protective responses against Streptococcus pneumoniae. Infect Immun (1998) 1.33
Evidence for separate genetic defects in C3H/HeJ and C3HeB/FeJ mice, that affect susceptibility to gram-negative infections. J Immunol (1985) 1.32
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Pneumococcal surface protein A of invasive Streptococcus pneumoniae isolates from Colombian children. Emerg Infect Dis (2001) 1.30
Phagocytosis and killing of salmonella typhimurium by peritoneal exudate cells. Infect Immun (1981) 1.29
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B cell subsets and differential responses to mitogens. Immunol Rev (1982) 1.26
Isoelectric focusing of immunoglobulins: improved methodology. J Immunol Methods (1980) 1.26
Multiple VH gene segments encode murine antistreptococcal antibodies. J Exp Med (1984) 1.26
Synthetic idiotypes: the third hypervariable region of murine anti-dextran antibodies. Cell (1983) 1.26
Cell surface antigens expressed by subsets of pre-B cells and B cells. J Immunol (1984) 1.26
Protein serotyping of Streptococcus pneumoniae based on reactivity to six monoclonal antibodies. Microb Pathog (1988) 1.25
Oral immunization with PspA elicits protective humoral immunity against Streptococcus pneumoniae infection. Infect Immun (1997) 1.24
Immune cryoglobulins in rabbit streptococcal antiserum. J Immunol (1968) 1.24
Fusion proteins containing family 1 and family 2 PspA fragments elicit protection against Streptococcus pneumoniae that correlates with antibody-mediated enhancement of complement deposition. Infect Immun (2007) 1.23
Murine pancreatic beta-cells express H-2K and H-2D but not Ia antigens. J Exp Med (1980) 1.23
Development of a multi-specificity opsonophagocytic killing assay. Vaccine (2000) 1.22
Induction of rejection of successful allografts of rat islets by donor peritoneal exudate cells. Transplantation (1979) 1.22