Published in Science on July 14, 1972
Genetic control of responses to bacterial lipopolysaccharides in mice. I. Evidence for a single gene that influences mitogenic and immunogenic respones to lipopolysaccharides. J Exp Med (1974) 4.48
Genetics of a new IgVH (T15 idiotype) marker in the mouse regulating natural antibody to phosphorylcholine. J Exp Med (1974) 3.64
Evidence for the linkage of the IGC H locus to a gene controlling the idiotypic specificity of anti-p-azophenylarsonate antibodies in strain A mice. J Exp Med (1973) 3.18
Immunochemical analysis of the cross-reacting idiotypes of mouse myeloma proteins with anti-dextran activity and normal anti-dextran antibody. Proc Natl Acad Sci U S A (1973) 2.21
Distribution of a cross-reactive idiotypic specificity in inbred strains of mice. J Exp Med (1973) 2.13
Congenic mouse strains: the expression of a hidden immunoglobulin allotype in a congenic partner strain of BALB-c mice. J Exp Med (1974) 2.13
Interactive effect of Gm allotypes and HLA-B locus antigens on the human antibody response to a bacterial antigen. Clin Exp Immunol (1980) 2.12
Clonal nature of the immune response to phosphorylcholine. IV. Idiotypic uniformity of binding site-associated antigenic determinants among mouse antiphosphorylcholine antibodies. J Exp Med (1974) 2.02
Segregation at a locus determining an immunoglobulin genetic marker for the light chain variable region affects inheritance of expression of an idiotype. Proc Natl Acad Sci U S A (1977) 1.97
Multiple individual and cross-specific indiotypes on 13 levan-binding myeloma proteins of BALB/c mice. J Exp Med (1975) 1.94
Inheritance of antibody specificity. I. Anti-(4-hydroxy-3-nitrophenyl)acetyl of the mouse primary response. J Exp Med (1974) 1.82
Mouse lambda-chain sequences. Proc Natl Acad Sci U S A (1973) 1.78
Idiotypic analysis of lymphocytes in vitro. II. Genetic control of T-helper cell responsiveness to anti-idiotypic antibody. J Exp Med (1976) 1.71
The diversity of the influenza-specific primary B-cell repertoire in BALB/c mice. J Exp Med (1978) 1.69
Influence of molecular structure on the tolerogenicity of bacterial dextrans. I. The alpha1--6-linked epitope of dextran B512. Immunology (1975) 1.56
Inheritance of antibody specificity V. Anti-2-phenyloxazolone in the mouse. J Exp Med (1978) 1.55
Immunological unresponsiveness to thymus-independent antigens: two fundamentally different genetic mechanisms of B-cell unresponsiveness to dextran. J Exp Med (1977) 1.50
Immunochemical similarities between monoclonal antibacterial Waldenstrom's macroglobulins and monoclonal anti-DNA lupus autoantibodies. J Exp Med (1985) 1.49
Differential expression of an equivalent clonotype among BALB/c and C57BL/6 mice. J Exp Med (1978) 1.49
IgG heavy chain allotypes (Gm) in autoimmune diseases. Clin Exp Immunol (1980) 1.46
Structural correlates of cross-reactive and individual idiotypic determinants on murine antibodies to alpha-(1 leads to 3) dextran. J Exp Med (1980) 1.46
Induction of antiphosphorylcholine antibody formation by anti-idiotypic antibodies. J Exp Med (1975) 1.45
Inheritance of immunoglobulin M rheumatoid-factor idiotypes. J Clin Invest (1980) 1.41
Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production. J Exp Med (2006) 1.36
Immunologic properties of bacterial lipopolysaccharide (LPS). III. Genetic linkage between the in vitro mitogenic and in vivo adjuvant properties of LPS. J Exp Med (1976) 1.34
On a regulatory gene controlling the expression of the murine lambda1 light chain. J Exp Med (1978) 1.32
Correlation between G2m(n) immunoglobulin allotype and human antibody response and susceptibility to polysaccharide encapsulated bacteria. J Clin Invest (1985) 1.32
Light chain editing in kappa-deficient animals: a potential mechanism of B cell tolerance. J Exp Med (1994) 1.29
Chromosomal locations of mouse immunoglobulin genes. Proc Natl Acad Sci U S A (1978) 1.29
Binding to idiotypic determinants of large proportions of thymus-derived lymphocytes in idiotypically suppressed mice. Proc Natl Acad Sci U S A (1977) 1.26
Clonal dominance. I. Restricted nature of the IgM antibody response to group A streptococcal carbohydrate in mice. J Exp Med (1975) 1.24
Restriction of gene expression in B lymphocytes and their progeny. I. Commitment to immunoglobulin allotype. J Exp Med (1974) 1.24
Linkage between the frequency of muscular weakness and loci that regulate immune responsiveness in murine experimental myasthenia gravis. J Exp Med (1980) 1.23
The natural abundance of lambda2-light chains in inbred mice. J Exp Med (1978) 1.23
Fine idiotype analysis of B cell precursors in the T-dependent and T-independent responses to alpha 1-3 dextran in BALB/c mice. J Exp Med (1983) 1.21
Immunochemical analysis of the idiotypes of mouse myeloma proteins with specificity for levan or dextran. J Exp Med (1974) 1.20
Polymorphisms of a human variable heavy chain gene show linkage with constant heavy chain genes. Proc Natl Acad Sci U S A (1984) 1.20
An idiotypic cross-reaction between allotype a3 and allotype a negative rabbit antibodies to streptococcal carbohydrate. J Exp Med (1973) 1.18
Influence of reticuloendothelial blockade on the induction of tolerance and immunity by polysaccharides. Immunology (1976) 1.17
Influence of molecular structure on the tolerogenicity of bacterial dextrans. II. The alpha1--3-linked epitope of dextran B1355. Immunology (1975) 1.17
Genetics of the idotype of BALB/c myeloma S117: multiple chromosomal loci for Vh genes encoding specificity for group A streptococcal carbohydrate. J Exp Med (1976) 1.15
Inheritance of antibody specificity. II. Anti-(4-hydroxy-5-bromo-3-nitrophenyl) acetyl in the mouse. J Exp Med (1975) 1.13
Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. VII. Idiotype-specific suppression of plaque-forming cell responses. J Exp Med (1981) 1.09
Generation of B cell memory to the bacterial polysaccharide alpha-1,3 dextran. J Immunol (2009) 1.08
Genetic basis for expression of the idiotypic network. One unique Ig VH germline gene accounts for the major family of Ab1 and Ab3 (Ab1') antibodies of the GAT system. J Exp Med (1986) 1.04
Influence of molecular structure of the tolerogenicity of bacterial dextrans. III. Dissociation between tolerance and immunity to the alpha1--6- and alpha1--3-linked epitopes of dextran B1355. Immunology (1975) 1.04
Preferential use of DH reading frame 2 alters B cell development and antigen-specific antibody production. J Immunol (2008) 1.04
Genetics of restricted antibodies to streptococcal group polysaccharides in mice. I. Strain differences of isoelectric focusing spectra of group A hyperimmune antisera. J Exp Med (1974) 1.03
Functional, non-clonal IgMa-restricted B cell receptor interactions with the HIV-1 envelope gp41 membrane proximal external region. PLoS One (2009) 1.03
Genetic control of DH reading frame and its effect on B-cell development and antigen-specifc antibody production. Crit Rev Immunol (2010) 1.02
Structural, functional, and idiotypic characteristics of a phosphorylcholine-binding IgA myeloma protein of C57BL/ka allotype. J Exp Med (1975) 0.99
Feedback suppression of the immune response in vitro. II. IgVH-restricted antibody-dependent suppression. J Exp Med (1980) 0.99
Restricted association of V and J-C gene segments for mouse lambda chains. Proc Natl Acad Sci U S A (1984) 0.98
A common idiotype on human macroglobulins with anti-I and anti-i specificity. Clin Exp Immunol (1975) 0.98
Genetic control of immune response. The dose of antigen given in aqueous solution is critical in determining which mouse strain is high responder to poly(LTyr, LGlu)-poly(LPro)--poly(LLys). J Exp Med (1975) 0.96
Induction of a cross-reactive idiotype dextran-positive antibody response in two IgH-Cb mouse strains treated with anti-J558 cross-reactive idiotype antibodies. J Exp Med (1983) 0.95
Antigen dose and strain variation as factors in the genetic control of the immune response to sperm whale myoglobin. Immunology (1978) 0.93
Shared antigenic determinants by mitogen receptors and antibody molecules to the same thymus-independent antigen. J Exp Med (1978) 0.92
Non-dinitrophenyl-binding immunoglobulin that bears a dominant idiotype (Id460) associated with antidinitrophenyl antibody is specific for an antigen on Pasteurella pneumotropica. J Exp Med (1984) 0.91
Optimization of a murine immunization model for study of PF4/heparin antibodies. J Thromb Haemost (2009) 0.91
Role of variable region gene expression and environmental selection in determining the antiphosphorylcholine B cell repertoire. J Exp Med (1983) 0.90
Immune response against two epitopes on the same thymus-independent polysaccharide carrier. 1. Role of epitope density in carrier-dependent immunity and tolerance. Immunology (1977) 0.89
The genetic control of T cell-meditated immunity. I. Characterization of a mouse strain whose low responsiveness is inherited as a recessive trait. Immunology (1974) 0.89
Idiotypic specificity of rabbit antibodies to streptococcal group polysaccharides. J Exp Med (1973) 0.89
Genetic and temporal control of neonatal antibody expression. J Exp Med (1983) 0.89
Genetic bases of autoimmune hepatitis. Dig Dis Sci (2002) 0.86
Inheritance of antibody specificity. III. A new VH gene controls fine specificity of anti-p-azobenzenearsonate coupled to the carbon atom 5 of hydroxyphenylacetic acid in the mouse. J Exp Med (1976) 0.85
Strain-specific silencing of a predominant antidextran clonotype family. J Exp Med (1985) 0.85
Strain variations in the murine cellular immune response to the phenolic glycolipid I antigen of Mycobacterium leprae. Infect Immun (1986) 0.83
Terminal deoxynucleotidyl transferase is required for an optimal response to the polysaccharide α-1,3 dextran. J Immunol (2009) 0.83
The mouse antibody heavy chain repertoire is germline-focused and highly variable between inbred strains. Philos Trans R Soc Lond B Biol Sci (2015) 0.82
Surface immunoglobulins of lymphocytes in plasmacytoma. V. The effect of RNA-rich extract from mouse plasmacytoma MOPC 104E on the immune response. Clin Exp Immunol (1976) 0.80
Limiting CDR-H3 diversity abrogates the antibody response to the bacterial polysaccharide α 1→3 dextran. J Immunol (2011) 0.80
Genetic control of the immune response to staphylococcal nuclease. VIII. Mapping of genes for antibodies to different antigenic regions of nuclease. J Exp Med (1978) 0.80
Antibodies that bind complex glycosaminoglycans accumulate in the Golgi. Proc Natl Acad Sci U S A (2013) 0.79
Absence of N addition facilitates B cell development, but impairs immune responses. Immunogenetics (2011) 0.78
Determination of the kappa anti-alpha(1,3) dextran immune response difference by A gene(s) in the VKappa-locus of mice. J Exp Med (1979) 0.77
The genotype of mice influences the autoimmune response to spliceosome proteins induced by cytomegalovirus gB immunization. Clin Exp Immunol (2002) 0.76
Lymphocytes. 1. Function. Genetic restrictions in the immune response. J Clin Pathol Suppl (R Coll Pathol) (1979) 0.76
Pulmonary α-1,3-Glucan-Specific IgA-Secreting B Cells Suppress the Development of Cockroach Allergy. J Immunol (2016) 0.75
Immune response gene regulation of the humoral immune response to Porphyromonas gingivalis fimbriae in mice. Immunology (1991) 0.75
Immunological Outcomes of Antibody Binding to Glycans Shared between Microorganisms and Mammals. J Immunol (2016) 0.75
Idiotype-specific T lymphocytes. II. capability of generation of idiotype-specific T lymphocytes is determined by corresponding VH gene. J Exp Med (1983) 0.75
A single DH gene segment is sufficient for the establishment of an asthma phenotype in a murine model of allergic airway inflammation. Int Arch Allergy Immunol (2011) 0.75
The Sr1 gene that controls diversity of the anti-inulin antibody response maps to mouse chromosome 14. Immunogenetics (2003) 0.75
Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin. Proc Natl Acad Sci U S A (1984) 5.49
Receptor editing: an approach by autoreactive B cells to escape tolerance. J Exp Med (1993) 5.49
Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression. Nature (1981) 4.78
Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation. J Exp Med (1990) 4.46
Identification and nucleotide sequence of a diversity DNA segment (D) of immunoglobulin heavy-chain genes. Nature (1981) 4.19
Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin. J Exp Med (1985) 3.54
Transcription of mouse kappa chain genes: implications for allelic exclusion. Proc Natl Acad Sci U S A (1980) 3.38
Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice. Nature (1991) 3.32
Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma. Nature (1986) 3.24
Rearrangement of genetic information may produce immunoglobulin diversity. Nature (1979) 2.84
B lymphocytes may escape tolerance by revising their antigen receptors. J Exp Med (1993) 2.78
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Genetic and structural evidence for antigen selection of anti-DNA antibodies. Annu Rev Immunol (1994) 2.45
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Immunochemical analysis of the cross-reacting idiotypes of mouse myeloma proteins with anti-dextran activity and normal anti-dextran antibody. Proc Natl Acad Sci U S A (1973) 2.21
Smoking is a risk factor for recurrence of intestinal stricture after endoscopic dilation in Crohn's disease. Aliment Pharmacol Ther (2012) 2.07
Genes for immunoglobulin heavy chain and serum prealbumin protein are linked in mouse. Nature (1975) 2.01
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Revising B cell receptors. J Exp Med (2000) 1.96
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Light chain replacement: a new model for antibody gene rearrangement. J Exp Med (1995) 1.90
Editors and editing of anti-DNA receptors. Immunity (2001) 1.90
The site and stage of anti-DNA B-cell deletion. Nature (1995) 1.87
Multiplicity of germline genes specifying a group of related mouse kappa chains with implications for the generation of immunoglobulin diversity. Nature (1979) 1.85
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Mouse lambda-chain sequences. Proc Natl Acad Sci U S A (1973) 1.78
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Somatic mutation and light chain rearrangement generate autoimmunity in anti-single-stranded DNA transgenic MRL/lpr mice. J Exp Med (1999) 1.36
Structural patterns in anti-DNA antibodies from MRL/lpr mice. Cold Spring Harb Symp Quant Biol (1989) 1.35
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Mouse immunoglobulin heavy chains are coded by multiple germ line variable region genes. Proc Natl Acad Sci U S A (1974) 1.22
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New methods for the treatment of lunatomalacia. Reconstr Surg Traumatol (1969) 1.22
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