A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor.

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Published in J Biol Chem on December 27, 2000

Authors

A Yart1, M Laffargue, P Mayeux, S Chretien, C Peres, N Tonks, S Roche, B Payrastre, H Chap, P Raynal

Author Affiliations

1: INSERM U326, IFR 30, Hôpital Purpan, Toulouse 31059, INSERM U363, Hôpital Cochin, 27 rue du Faubourg Saint-Jacques, Paris 75014, France.

Associated clinical trials:

Study of Metabolic Modifications in Children With Noonan Syndrome (MetabNoonan) | NCT02383316

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