Published in FASEB J on May 01, 2001
Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science (2010) 12.15
Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev (2008) 5.28
A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker. Circ Res (2010) 3.99
Vascular remodeling of the mouse yolk sac requires hemodynamic force. Development (2007) 3.26
The emergence of hematopoietic stem cells is initiated in the placental vasculature in the absence of circulation. Cell Stem Cell (2008) 3.09
What keeps us ticking: a funny current, a calcium clock, or both? J Mol Cell Cardiol (2009) 2.99
Biomechanical forces promote embryonic haematopoiesis. Nature (2009) 2.99
Restricted inactivation of serum response factor to the cardiovascular system. Proc Natl Acad Sci U S A (2004) 2.98
periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype. Mol Cell Biol (2005) 2.94
Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages. J Exp Med (2012) 2.69
All primitive and definitive hematopoietic progenitor cells emerging before E10 in the mouse embryo are products of the yolk sac. Blood (2007) 2.31
Autonomous murine T-cell progenitor production in the extra-embryonic yolk sac before HSC emergence. Blood (2012) 1.72
Early myocardial function affects endocardial cushion development in zebrafish. PLoS Biol (2004) 1.59
Origin and differentiation of microglia. Front Cell Neurosci (2013) 1.58
Fundamental importance of Na+-Ca2+ exchange for the pacemaking mechanism in guinea-pig sino-atrial node. J Physiol (2006) 1.58
Embryonic day 9 yolk sac and intra-embryonic hemogenic endothelium independently generate a B-1 and marginal zone progenitor lacking B-2 potential. Proc Natl Acad Sci U S A (2011) 1.55
Haemogenic endocardium contributes to transient definitive haematopoiesis. Nat Commun (2013) 1.36
Inositol-1,4,5-trisphosphate-mediated spontaneous activity in mouse embryonic stem cell-derived cardiomyocytes. J Physiol (2007) 1.29
Mutation in sodium-calcium exchanger 1 (NCX1) causes cardiac fibrillation in zebrafish. Proc Natl Acad Sci U S A (2005) 1.24
Initiation of embryonic cardiac pacemaker activity by inositol 1,4,5-trisphosphate-dependent calcium signaling. Mol Biol Cell (2005) 1.23
The ryanodine receptor modulates the spontaneous beating rate of cardiomyocytes during development. Proc Natl Acad Sci U S A (2002) 1.23
Calcium extrusion is critical for cardiac morphogenesis and rhythm in embryonic zebrafish hearts. Proc Natl Acad Sci U S A (2005) 1.21
Intracellular Ca2+ oscillations, a potential pacemaking mechanism in early embryonic heart cells. J Gen Physiol (2007) 1.20
Dynamic responses of endothelial cells to changes in blood flow during vascular remodeling of the mouse yolk sac. Development (2013) 1.13
Na+/Ca2+ exchanger is a determinant of excitation-contraction coupling in human embryonic stem cell-derived ventricular cardiomyocytes. Stem Cells Dev (2010) 1.13
Hematopoietic stem cell emergence in the conceptus and the role of Runx1. Int J Dev Biol (2010) 1.11
Monocilia in the embryonic mouse heart suggest a direct role for cilia in cardiac morphogenesis. Dev Dyn (2008) 1.10
Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence. J Exp Med (2015) 1.07
Zebrafish as an animal model to study ion homeostasis. Pflugers Arch (2013) 1.06
A short history of hemogenic endothelium. Blood Cells Mol Dis (2013) 1.05
Excitation-contraction coupling of the mouse embryonic cardiomyocyte. J Gen Physiol (2008) 1.04
Myocardial function with reduced expression of the sodium-calcium exchanger. J Card Fail (2010) 1.03
Advances in the understanding of mineral and bone metabolism in inflammatory bowel diseases. Am J Physiol Gastrointest Liver Physiol (2010) 1.02
The sodium/calcium exchanger family-SLC8. Pflugers Arch (2003) 0.97
The importance of microglia in the development of the vasculature in the central nervous system. Vasc Cell (2013) 0.95
Genetic inhibition of Na+-Ca2+ exchanger current disables fight or flight sinoatrial node activity without affecting resting heart rate. Circ Res (2012) 0.93
High levels of synaptosomal Na(+)-Ca(2+) exchangers (NCX1, NCX2, NCX3) co-localized with amyloid-beta in human cerebral cortex affected by Alzheimer's disease. Cell Calcium (2011) 0.93
Definitive Hematopoiesis in the Yolk Sac Emerges from Wnt-Responsive Hemogenic Endothelium Independently of Circulation and Arterial Identity. Stem Cells (2015) 0.92
Triple threat: the Na+/Ca2+ exchanger in the pathophysiology of cardiac arrhythmia, ischemia and heart failure. Curr Drug Targets (2011) 0.90
Regulation of Ncx1 expression. Identification of regulatory elements mediating cardiac-specific expression and up-regulation. J Biol Chem (2006) 0.90
Calcium buffering and excitation-contraction coupling in developing avian myocardium. Biophys J (2004) 0.89
Lymphoid progenitor emergence in the murine embryo and yolk sac precedes stem cell detection. Stem Cells Dev (2014) 0.89
Vascular development and hemodynamic force in the mouse yolk sac. Front Physiol (2014) 0.88
Modern concepts concerning the origin of the heartbeat. Physiology (Bethesda) (2013) 0.88
Capturing structure and function in an embryonic heart with biophotonic tools. Front Physiol (2014) 0.87
Hematopoietic stem cell development in the placenta. Int J Dev Biol (2010) 0.86
Atrioventricular conduction and arrhythmias at the initiation of beating in embryonic mouse hearts. Dev Dyn (2010) 0.85
Overcoming obstacles in the search for the site of hematopoietic stem cell emergence. Cell Stem Cell (2008) 0.85
The importance of Ca(2+)-dependent mechanisms for the initiation of the heartbeat. Front Physiol (2015) 0.85
Mathematical model of mouse embryonic cardiomyocyte excitation-contraction coupling. J Gen Physiol (2008) 0.84
Neural crest defects in ephrin-B2 mutant mice are non-autonomous and originate from defects in the vasculature. Dev Biol (2015) 0.84
Changes in vitelline and utero-placental hemodynamics: implications for cardiovascular development. Front Physiol (2014) 0.83
Uncovering the Number and Clonal Dynamics of Mesp1 Progenitors during Heart Morphogenesis. Cell Rep (2015) 0.83
Heterozygous inactivation of the Na/Ca exchanger increases glucose-induced insulin release, β-cell proliferation, and mass. Diabetes (2011) 0.82
Chronic administration of KB-R7943 induces up-regulation of cardiac NCX1. J Biol Chem (2009) 0.82
Transcription factor ISL1 is essential for pacemaker development and function. J Clin Invest (2015) 0.81
Combinatorial transcriptional interaction within the cardiac neural crest: a pair of HANDs in heart formation. Birth Defects Res C Embryo Today (2004) 0.81
Mechanisms underlying the cardiac pacemaker: the role of SK4 calcium-activated potassium channels. Acta Pharmacol Sin (2016) 0.80
Placenta as a source of hematopoietic stem cells. Trends Mol Med (2010) 0.79
Initiation of electron transport chain activity in the embryonic heart coincides with the activation of mitochondrial complex 1 and the formation of supercomplexes. PLoS One (2014) 0.79
Stem cells: The stress of forming blood cells. Nature (2009) 0.79
Calcium signalling in developing cardiomyocytes: implications for model systems and disease. J Physiol (2015) 0.78
Gene replacement strategies to test the functional redundancy of basic helix-loop-helix transcription factor. Pediatr Cardiol (2010) 0.77
Correction: The importance of microglia in the development of the vasculature in the central nervous system. Vasc Cell (2013) 0.77
Calcium channel blockade in embryonic cardiac progenitor cells disrupts normal cardiac cell differentiation. Stem Cells Dev (2010) 0.77
Involvement of Na+-Ca2+ exchanger in cAMP-mediated relaxation in mice aorta: evaluation using transgenic mice. Br J Pharmacol (2007) 0.76
Conditional knockout of smooth muscle sodium calcium exchanger type-1 lowers blood pressure and attenuates Angiotensin II-salt hypertension. Physiol Rep (2015) 0.76
Ectopic Noggin in a Population of Nfatc1 Lineage Endocardial Progenitors Induces Embryonic Lethality. J Cardiovasc Dev Dis (2014) 0.76
Connecting teratogen-induced congenital heart defects to neural crest cells and their effect on cardiac function. Birth Defects Res C Embryo Today (2014) 0.76
Novel methods for determining hematopoietic stem and progenitor cell emergence in the murine yolk sac. Int J Dev Biol (2010) 0.76
Persistent Noggin arrests cardiomyocyte morphogenesis and results in early in utero lethality. Dev Dyn (2014) 0.75
The Indispensable Roles of Microglia and Astrocytes during Brain Development. Front Hum Neurosci (2016) 0.75
Calcium handling precedes cardiac differentiation to initiate the first heartbeat. Elife (2016) 0.75
A subset of cerebrovascular pericytes originates from mature macrophages in the very early phase of vascular development in CNS. Sci Rep (2017) 0.75
Ectopic expression of Cripto-1 in transgenic mouse embryos causes hemorrhages, fatal cardiac defects and embryonic lethality. Sci Rep (2016) 0.75
Intestinal absorption and renal reabsorption of calcium throughout postnatal development. Exp Biol Med (Maywood) (2017) 0.75
Sodium-calcium exchange mediated contraction in left anterior descending and left ventricular branch arteries. J Cell Mol Med (2009) 0.75
Abnormal arterial-venous fusions and fate specification in mouse embryos lacking blood flow. Sci Rep (2017) 0.75
Why are hematopoietic stem cells so 'sexy'? on a search for developmental explanation. Leukemia (2017) 0.75
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
The sequence of the human genome. Science (2001) 101.55
The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models. Bioinformatics (2003) 32.92
Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia. Nature (2004) 16.76
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity (2000) 16.03
Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor. Science (1992) 14.70
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science (1995) 13.15
Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat Med (2001) 10.36
Avian flu: H5N1 virus outbreak in migratory waterfowl. Nature (2005) 10.04
Prevention of allogeneic fetal rejection by tryptophan catabolism. Science (1998) 9.80
Highly pathogenic H5N1 influenza virus infection in migratory birds. Science (2005) 9.64
Establishment of multiple sublineages of H5N1 influenza virus in Asia: implications for pandemic control. Proc Natl Acad Sci U S A (2006) 9.26
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest (1999) 8.38
Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice. Nat Genet (1998) 7.89
Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis. Cell (2000) 6.70
A global profile of germline gene expression in C. elegans. Mol Cell (2000) 5.97
Pharmacological characterization of conduction over a Mahaim fiber: evidence for adenosine sensitive conduction. Pacing Clin Electrophysiol (1989) 5.94
Atomic structure of a thermostable subdomain of HIV-1 gp41. Proc Natl Acad Sci U S A (1997) 5.76
Preoperative chemotherapy in patients with operable breast cancer: nine-year results from National Surgical Adjuvant Breast and Bowel Project B-18. J Natl Cancer Inst Monogr (2001) 5.74
Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo. Nature (1990) 5.41
Structure of the replicating complex of a pol alpha family DNA polymerase. Cell (2001) 5.26
Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3. EMBO J (2000) 5.22
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol Cell (2001) 5.19
Indium phosphide nanowires as building blocks for nanoscale electronic and optoelectronic devices. Nature (2001) 5.09
Capecitabine/cisplatin versus 5-fluorouracil/cisplatin as first-line therapy in patients with advanced gastric cancer: a randomised phase III noninferiority trial. Ann Oncol (2009) 5.08
Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environment. Annu Rev Immunol (1999) 4.97
A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis. Cell (1998) 4.78
Emergence and predominance of an H5N1 influenza variant in China. Proc Natl Acad Sci U S A (2006) 4.49
Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice. J Virol (1994) 4.34
Improved stability of Drosophila larval neuromuscular preparations in haemolymph-like physiological solutions. J Comp Physiol A (1994) 4.24
Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I. Proc Natl Acad Sci U S A (2000) 4.22
Infectivity, transmission, and pathology of human-isolated H7N9 influenza virus in ferrets and pigs. Science (2013) 4.17
Anthropogenic warming of Earth's climate system. Science (2001) 3.94
Effect of long-term estrogen deprivation on apoptotic responses of breast cancer cells to 17beta-estradiol. J Natl Cancer Inst (2001) 3.88
Detection of Norwalk virus in stool by polymerase chain reaction. J Clin Microbiol (1992) 3.82
Quantum annealing with manufactured spins. Nature (2011) 3.81
SURF1, encoding a factor involved in the biogenesis of cytochrome c oxidase, is mutated in Leigh syndrome. Nat Genet (1998) 3.79
Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils. J Clin Invest (1996) 3.74
Insights into editing from an ile-tRNA synthetase structure with tRNAile and mupirocin. Science (1999) 3.71
The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: outcome of a pilot clinical study. Leukemia (2008) 3.69
Role of miR-143 targeting KRAS in colorectal tumorigenesis. Oncogene (2009) 3.64
Insertional mutagenesis of genes required for seed development in Arabidopsis thaliana. Genetics (2001) 3.49
Multiferroic BaTiO3-CoFe2O4 Nanostructures. Science (2004) 3.49
Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID). Nature (1990) 3.42
Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils. J Exp Med (1996) 3.33
MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation. Mol Cell Biol (1995) 3.32
Appendicular skeletal muscle mass: measurement by dual-photon absorptiometry. Am J Clin Nutr (1990) 3.24
Environmental effects on photosynthesis, nitrogen-use efficiency, and metabolite pools in leaves of sun and shade plants. Plant Physiol (1987) 3.23
The crystal structure of a T cell receptor in complex with peptide and MHC class II. Science (1999) 3.23
Epithelial sodium channel regulated by aldosterone-induced protein sgk. Proc Natl Acad Sci U S A (1999) 3.19
The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution. EMBO J (1994) 3.18
The genesis and evolution of H9N2 influenza viruses in poultry from southern China, 2000 to 2005. J Virol (2007) 3.12
Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites. Eur J Neurosci (1999) 3.10
Prediction of body cell mass, fat-free mass, and total body water with bioelectrical impedance analysis: effects of race, sex, and disease. Am J Clin Nutr (1996) 3.06
Properties of hyperpolarization-activated pacemaker current defined by coassembly of HCN1 and HCN2 subunits and basal modulation by cyclic nucleotide. J Gen Physiol (2001) 3.04
Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine. Int Immunol (1999) 2.96
Cell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription. Genes Dev (2000) 2.90
Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex. Genes Dev (1992) 2.86
Structure of Taq polymerase with DNA at the polymerase active site. Nature (1996) 2.84
Adherence to statin treatment and readmission of patients after myocardial infarction: a six year follow up study. Heart (2002) 2.83
The 2.4 A crystal structure of the bacterial chaperonin GroEL complexed with ATP gamma S. Nat Struct Biol (1996) 2.81
Relation of BMI to fat and fat-free mass among children and adolescents. Int J Obes (Lond) (2005) 2.80
Micron-resolution ranging of cornea anterior chamber by optical reflectometry. Lasers Surg Med (1991) 2.80
Sustained secretion of human alpha-1-antitrypsin from murine muscle transduced with adeno-associated virus vectors. Proc Natl Acad Sci U S A (1998) 2.80
Magnitude of body-cell-mass depletion and the timing of death from wasting in AIDS. Am J Clin Nutr (1989) 2.75
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1. Proc Natl Acad Sci U S A (1994) 2.71
Critical role for alpha/beta and gamma interferons in persistence of lymphocytic choriomeningitis virus by clonal exhaustion of cytotoxic T cells. J Virol (2001) 2.69
Structure and cell cycle-regulated transcription of the human cyclin A gene. Proc Natl Acad Sci U S A (1994) 2.69
Development of calibrated viral load standards for group M subtypes of human immunodeficiency virus type 1 and performance of an improved AMPLICOR HIV-1 MONITOR test with isolates of diverse subtypes. J Clin Microbiol (1999) 2.68
Lower receptor avidity required for thymic clonal deletion than for effector T-cell function. Nature (1991) 2.66
Posterior component separation with transversus abdominis release successfully addresses recurrent ventral hernias following anterior component separation. Hernia (2014) 2.64
Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circ Res (1994) 2.64
Genetic relationships of penicillin-susceptible and -resistant Streptococcus pneumoniae strains isolated on different continents. Infect Immun (1992) 2.62
Crystal structure of Thermus aquaticus DNA polymerase. Nature (1995) 2.62
MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein. Mol Cell Biol (2001) 2.58
Frizzled-related protein variants are risk factors for hip osteoarthritis. Arthritis Rheum (2006) 2.57
Cyclin A is required in S phase in normal epithelial cells. Biochem Biophys Res Commun (1992) 2.55
BRCA1 inhibition of estrogen receptor signaling in transfected cells. Science (1999) 2.54
A hepatic lipase (LIPC) allele associated with high plasma concentrations of high density lipoprotein cholesterol. Proc Natl Acad Sci U S A (1997) 2.53
Sex lethal controls dosage compensation in Drosophila by a non-splicing mechanism. Nature (1997) 2.52
Novel insights into the genetics, biochemistry, and immunocytochemistry of the 30-kilodalton major extracellular protein of Mycobacterium tuberculosis. Infect Immun (1996) 2.43
Estimation of extracellular and total body water by multiple-frequency bioelectrical-impedance measurement. Am J Clin Nutr (1991) 2.42
DNA looping by Ku and the DNA-dependent protein kinase. Proc Natl Acad Sci U S A (1997) 2.39
Blood-pressure lowering for the secondary prevention of stroke. Lancet (2001) 2.39
Periostin (an osteoblast-specific factor) is expressed within the embryonic mouse heart during valve formation. Mech Dev (2001) 2.37
Regulation of interleukin-12 expression in human monocytes: selective priming by interferon-gamma of lipopolysaccharide-inducible p35 and p40 genes. Blood (1995) 2.36
Upregulated TRP and enhanced capacitative Ca(2+) entry in human pulmonary artery myocytes during proliferation. Am J Physiol Heart Circ Physiol (2001) 2.35
Human cytotoxic T-cell memory: long-lived responses to vaccinia virus. J Virol (1996) 2.35
p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation. J Biol Chem (2000) 2.31
Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing. Bone (2005) 2.30
An investigation of the storage and biosynthesis of phenylpropenes in sweet basil. Plant Physiol (2001) 2.27
Application of PCR to detect Norwalk virus in fecal specimens from outbreaks of gastroenteritis. J Clin Microbiol (1994) 2.27
Jumonji, a nuclear protein that is necessary for normal heart development. Circ Res (2000) 2.26
Establishment of influenza A virus (H6N1) in minor poultry species in southern China. J Virol (2007) 2.26
Diagnosis of attention-deficit/hyperactivity disorder and use of psychotropic medication in very young children. Arch Pediatr Adolesc Med (1999) 2.25