Selection of zinc fingers that bind single-stranded telomeric DNA in the G-quadruplex conformation.

PubWeight™: 1.19‹?› | Rank: Top 10%

🔗 View Article (PMID 11170401)

Published in Biochemistry on January 23, 2001

Authors

M Isalan1, S D Patel, S Balasubramanian, Y Choo

Author Affiliations

1: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.

Articles citing this

Prevalence of quadruplexes in the human genome. Nucleic Acids Res (2005) 7.79

Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics. Nucleic Acids Res (2007) 3.49

Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans. Hum Mol Genet (2012) 1.77

G-quadruplex structures are stable and detectable in human genomic DNA. Nat Commun (2013) 1.72

Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression. Nucleic Acids Res (2009) 1.15

A non-canonical DNA structure is a binding motif for the transcription factor SP1 in vitro. Nucleic Acids Res (2011) 1.12

Unfolding of DNA quadruplexes induced by HIV-1 nucleocapsid protein. Nucleic Acids Res (2005) 1.12

The relationship of potential G-quadruplex sequences in cis-upstream regions of the human genome to SP1-binding elements. Nucleic Acids Res (2008) 1.06

Zinc-finger transcription factors are associated with guanine quadruplex motifs in human, chimpanzee, mouse and rat promoters genome-wide. Nucleic Acids Res (2011) 1.04

Selective recognition of a DNA G-quadruplex by an engineered antibody. Biochemistry (2008) 1.02

Exploring the recognition of quadruplex DNA by an engineered Cys2-His2 zinc finger protein. Biochemistry (2006) 1.02

Inhibition of human telomerase activity by an engineered zinc finger protein that binds G-quadruplexes. Biochemistry (2004) 0.98

U3 region in the HIV-1 genome adopts a G-quadruplex structure in its RNA and DNA sequence. Biochemistry (2014) 0.92

Replication of the results of genome-wide and candidate gene association studies on telomere length in a Korean population. Korean J Intern Med (2015) 0.77

Transfecting RNA quadruplexes results in few transcriptome perturbations. RNA Biol (2012) 0.76

RNA G-quadruplexes in biology: Principles and molecular mechanisms. J Mol Biol (2017) 0.75

Articles by these authors

(truncated to the top 100)

Exploring the DNA-binding specificities of zinc fingers with DNA microarrays. Proc Natl Acad Sci U S A (2001) 5.08

Synergy between adjacent zinc fingers in sequence-specific DNA recognition. Proc Natl Acad Sci U S A (1997) 3.32

A rapid, generally applicable method to engineer zinc fingers illustrated by targeting the HIV-1 promoter. Nat Biotechnol (2001) 3.12

Comprehensive DNA recognition through concerted interactions from adjacent zinc fingers. Biochemistry (1998) 2.51

Molecular analysis of NOZZLE, a gene involved in pattern formation and early sporogenesis during sex organ development in Arabidopsis thaliana. Proc Natl Acad Sci U S A (1999) 2.35

Synthesis and study of antibacterial and antifungal activities of novel 1-[2-(benzoxazol-2-yl)ethoxy]- 2,6-diarylpiperidin-4-ones. Eur J Med Chem (2004) 2.34

T1rho-relaxation in articular cartilage: effects of enzymatic degradation. Magn Reson Med (1997) 2.30

Protein alchemy: changing beta-sheet into alpha-helix. Nat Struct Biol (1997) 2.23

Cutaneous manifestations in patients with chronic renal failure on hemodialysis. Indian J Dermatol Venereol Leprol (2006) 2.19

Improved DNA binding specificity from polyzinc finger peptides by using strings of two-finger units. Proc Natl Acad Sci U S A (2001) 2.13

Recombinant HIV-1 nucleocapsid protein accelerates HIV-1 reverse transcriptase catalyzed DNA strand transfer reactions and modulates RNase H activity. Biochemistry (1994) 2.08

Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction. Mol Psychiatry (2012) 2.07

Epitope mapping of human anti-adeno-associated virus type 2 neutralizing antibodies: implications for gene therapy and virus structure. J Virol (2000) 1.98

Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms. Am J Med Genet B Neuropsychiatr Genet (2009) 1.92

Design of polyzinc finger peptides with structured linkers. Proc Natl Acad Sci U S A (2001) 1.88

Trends in cancer incidence in Chennai city (1982-2006) and statewide predictions of future burden in Tamil Nadu (2007-16). Natl Med J India (2011) 1.81

Synthesis and in vitro microbiological evaluation of imidazo(4,5-b)pyridinylethoxypiperidones. Eur J Med Chem (2005) 1.79

Identifying blood biomarkers for mood disorders using convergent functional genomics. Mol Psychiatry (2008) 1.78

Expression levels for many genes in human peripheral blood cells are highly sensitive to ex vivo incubation. Genes Immun (2004) 1.77

What makes a protein a protein? Hydrophobic core designs that specify stability and structural properties. Protein Sci (1996) 1.76

Photolabelling of a mitochondrially encoded subunit of NADH dehydrogenase with [3H]dihydrorotenone. FEBS Lett (1987) 1.74

Non-Arrhenius kinetics for the loop closure of a DNA hairpin. Proc Natl Acad Sci U S A (2001) 1.71

Predictors of spontaneous bleeding in Dengue. Indian J Pediatr (2004) 1.71

Identification of blood biomarkers for psychosis using convergent functional genomics. Mol Psychiatry (2009) 1.68

Peripheral blood gene expression profiling in rheumatoid arthritis. Genes Immun (2005) 1.66

Synthesis and NMR spectral studies of N-chloroacetyl-2,6-diarylpiperidin-4-ones. Spectrochim Acta A Mol Biomol Spectrosc (2007) 1.60

Technology for microarray analysis of gene expression. Curr Opin Biotechnol (1998) 1.58

Anti-tumor activity of human T cells expressing the CC49-zeta chimeric immune receptor. Hum Gene Ther (1999) 1.52

Rapid, high-throughput engineering of sequence-specific zinc finger DNA-binding proteins. Methods Enzymol (2001) 1.49

Profile of hemophagocytic lymphohistiocytosis in children in a tertiary care hospital in India. Indian Pediatr (2010) 1.45

Profile of EBV associated infectious mononucleosis. Indian Pediatr (2012) 1.45

Synthesis and NMR spectral studies of some 2,6-diarylpiperidin-4-one O-benzyloximes. Spectrochim Acta A Mol Biomol Spectrosc (2007) 1.43

OB-BP1/Siglec-6. a leptin- and sialic acid-binding protein of the immunoglobulin superfamily. J Biol Chem (1999) 1.41

Activation and clinical significance of the unfolded protein response in breast cancer. Br J Cancer (2009) 1.28

Titration calorimetric studies to elucidate the specificity of the interactions of polymyxin B with lipopolysaccharides and lipid A. Biochem J (1996) 1.27

Carcinoid tumor and inflammatory bowel disease: a study of eleven cases and review of the literature. Am J Gastroenterol (1997) 1.21

Dengue disease spectrum among infants in the 2001 dengue epidemic in Chennai, Tamil Nadu, India. J Clin Microbiol (2003) 1.18

Molecular characterization and modular analysis of human MyD88. Oncogene (1996) 1.15

Transmuting alpha helices and beta sheets. Fold Des (1997) 1.15

Synthesis and hybridization analysis of a small library of peptide-oligonucleotide conjugates. Nucleic Acids Res (1998) 1.14

4-Sulfamoylanilinium nitrate. Acta Crystallogr Sect E Struct Rep Online (2011) 1.13

Robotic surgery in gynecology. Scand J Surg (2009) 1.12

Synthesis, stereochemistry and antimicrobial evaluation of some N-morpholinoacetyl-2,6-diarylpiperidin-4-ones. Eur J Med Chem (2007) 1.11

T cell responses to a human cartilage autoantigen in the context of rheumatoid arthritis-associated and nonassociated HLA-DR4 alleles. Arthritis Rheum (1999) 1.11

Characterization of hematopoietic cell expansion, oxygen uptake, and glycolysis in a controlled, stirred-tank bioreactor system. Biotechnol Prog (1998) 1.10

Mefenamic acid--role as antipyretic. Indian Pediatr (2010) 1.08

Tracking operator state fluctuations in gene expression in single cells. Biophys J (2004) 1.08

Prophylactic central neck dissection for papillary thyroid cancer (Br J Surg 2013; 100: 410-418). Br J Surg (2013) 1.08

The 2001 dengue epidemic in Chennai. Indian J Pediatr (2005) 1.07

Convergent functional genomics of anxiety disorders: translational identification of genes, biomarkers, pathways and mechanisms. Transl Psychiatry (2011) 1.06

Rapsyn clusters and activates the synapse-specific receptor tyrosine kinase MuSK. Neuron (1996) 1.05

Glutamine deprivation facilitates tumour necrosis factor induced bacterial translocation in Caco-2 cells by depletion of enterocyte fuel substrate. Gut (2003) 1.05

Drug therapy of acute diarrhoea in children--actual practice and recommendations. Indian J Pediatr (2000) 1.02

Dynamics of protein relaxation in site-specific mutants of human myoglobin. Biochemistry (1993) 1.02

Ultrafast measurements of geminate recombination of NO with site-specific mutants of human myoglobin. J Mol Biol (1994) 0.99

Rheumatic fever and rheumatic heart disease in school children of Anand. J Assoc Physicians India (1986) 0.99

The site of synthesis of the iron-sulfur subunits of the flavoprotein and iron-protein fractions of human NADH dehydrogenase. J Biol Chem (1988) 0.98

Continuous microwave-assisted isoflavone extraction system: design and performance evaluation. Bioresour Technol (2009) 0.98

Efficacy of soy protein isolate as a fat replacer on physico-chemical and sensory characteristics of low-fat paneer. J Food Sci Technol (2010) 0.97

Mouse T cell membrane proteins Rt6-1 and Rt6-2 are arginine/protein mono(ADPribosyl)transferases and share secondary structure motifs with ADP-ribosylating bacterial toxins. J Biol Chem (1996) 0.97

Changing trends in antimicrobial resistance of Salmonella enterica serovar typhi and salmonella enterica serovar paratyphi A in Chennai. Indian J Pathol Microbiol (2009) 0.96

Ligand and proton exchange dynamics in recombinant human myoglobin mutants. J Mol Biol (1989) 0.96

Morphine directs T cells toward T(H2) differentiation. Surgery (2001) 0.95

Mechanism of metal-independent hydroxylation by Chromobacterium violaceum phenylalanine hydroxylase. Biochemistry (1995) 0.94

Molecular basis of mitochondrial myopathies: polypeptide analysis in complex-I deficiency. Lancet (1988) 0.94

Antidermatophytic activity of extracts from Psoralea corylifolia (Fabaceae) correlated with the presence of a flavonoid compound. J Ethnopharmacol (2004) 0.94

Morphine inhibits VEGF expression in myocardial ischemia. Surgery (2003) 0.93

Determination of glutamic acid decarboxylase 65 peptides presented by the type I diabetes-associated HLA-DQ8 class II molecule identifies an immunogenic peptide motif. J Immunol (1999) 0.93

Gunshot wounds in children under 10 years of age. A new epidemic. Am J Dis Child (1988) 0.93

Two novel human members of an emerging mammalian gene family related to mono-ADP-ribosylating bacterial toxins. Genomics (1997) 0.93

Convergent functional genomic studies of ω-3 fatty acids in stress reactivity, bipolar disorder and alcoholism. Transl Psychiatry (2011) 0.93

Differential gene expression patterns in porcine nuclear transfer embryos reconstructed with fetal fibroblasts and mesenchymal stem cells. Dev Dyn (2007) 0.92

Major histocompatibility complex-encoded antigen processing gene polymorphism in IDDM. Diabetes (1994) 0.92

Ultra-structural changes and developmental potential of porcine oocytes following vitrification. Anim Reprod Sci (2006) 0.92

What do parents of asthmatic children know about asthma?: An Indian perspective. Indian J Chest Dis Allied Sci (2005) 0.91

Use of fluorescence resonance energy transfer to investigate the conformation of DNA substrates bound to the Klenow fragment. Biochemistry (1998) 0.91

Microtubulin configuration and mitochondrial distribution after ultra-rapid cooling of bovine oocytes. Mol Reprod Dev (2002) 0.91

Genomic polymorphism, recombination, and linkage disequilibrium in human major histocompatibility complex-encoded antigen-processing genes. Proc Natl Acad Sci U S A (1992) 0.90

Immunogenicity and safety of a 13-valent pneumococcal conjugate vaccine in healthy infants and toddlers given with routine vaccines in India. Pediatr Infect Dis J (2013) 0.90

Engineering nucleic acid-binding proteins by phage display. Methods Mol Biol (2001) 0.90

3-Acetyl-4-hydroxy-phenyl acrylate. Acta Crystallogr Sect E Struct Rep Online (2009) 0.90

Systemic capillary leak syndrome resulting in compartment syndrome and the requirement for a surgical airway. Anaesthesia (2009) 0.89

Refined potential model for atomistic simulations of ionic liquid [bmim][PF6]. J Chem Phys (2007) 0.89

DNA methylation levels in porcine fetal fibroblasts induced by an inhibitor of methylation, 5-azacytidine. Cell Tissue Res (2006) 0.88

Prescribing pattern of zinc and antimicrobials in acute diarrhea. Indian Pediatr (2008) 0.88

Anatomy and dynamics of a ligand-binding pathway in myoglobin: the roles of residues 45, 60, 64, and 68. Biochemistry (1994) 0.88

Escherichia coli chorismate synthase catalyzes the conversion of (6S)-6-fluoro-5-enolpyruvylshikimate-3-phosphate to 6-fluorochorismate. Implications for the enzyme mechanism and the antimicrobial action of (6S)-6-fluoroshikimate. J Biol Chem (1995) 0.88

Hemorrhagic pleural effusion--sole manifestation of pancreatitis. Indian J Pediatr (1994) 0.87

Suprabasal expression of the human papillomavirus type 16 oncoproteins in mouse epidermis alters expression of cell cycle regulatory proteins. Carcinogenesis (2000) 0.86

2,3,4,9-Tetra-hydro-1H-carbazole. Acta Crystallogr Sect E Struct Rep Online (2008) 0.86

Effect of alpha-tocopherol supplementation during boar semen cryopreservation on sperm characteristics and expression of apoptosis related genes. Cryobiology (2008) 0.86

Morphine modulates lymph node-derived T lymphocyte function: role of caspase-3, -8, and nitric oxide. J Leukoc Biol (2001) 0.86

Engineered zinc finger proteins that respond to DNA modification by HaeIII and HhaI methyltransferase enzymes. J Mol Biol (2000) 0.85

Repair of ventral metrocele (gravid) in a goat. Vet Rec (1993) 0.85

CD38-mediated ribosylation of proteins. J Immunol (1995) 0.85

The safety of peri-articular local anaesthetic injection for patients undergoing total knee replacement with autologous blood transfusion: a randomised trial. J Bone Joint Surg Br (2012) 0.85

Use of the EST database resource to identify and clone novel mono(ADP-ribosyl)transferase gene family members. Adv Exp Med Biol (1997) 0.84

Tertiary structure of uracil-DNA glycosylase inhibitor protein. J Biol Chem (1995) 0.84

1-(2-Carb-oxy-eth-yl)-5-ethyl-2-methyl-pyridinium chloride. Acta Crystallogr Sect E Struct Rep Online (2012) 0.83

In vitro drug release behavior, mechanism and antimicrobial activity of rifampicin loaded low molecular weight PLGA-PEG-PLGA triblock copolymeric nanospheres. Curr Drug Deliv (2013) 0.83