Two-state allosteric behavior in a single-domain signaling protein.

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Published in Science on March 23, 2001

Authors

B F Volkman1, D Lipson, D E Wemmer, D Kern

Author Affiliations

1: National Magnetic Resonance Facility at Madison (NMRFAM), Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.

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Interproton distance bounds from 2D NOE intensities: effect of experimental noise and peak integration errors. J Biomol NMR (1995) 1.17

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[E: [Electron microscopic studies on the action of cobalt chloride on the exocrine pancreatic tissue in guinea pigs]. Virchows Arch B Cell Pathol (1969) 1.14

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trans-Diamminedichloroplatinum(II), a reversible RNA-protein cross-linking agent. Application to the ribosome and to an aminoacyl-tRNA synthetase/tRNA complex. Biochemistry (1987) 1.07

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Melting of a self-complementary DNA minicircle. Comparison of optical melting theory with exchange broadening of the nuclear magnetic resonance spectrum. J Mol Biol (1988) 1.06

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Phycobilins of cryptophycean algae. Occurrence of dihydrobiliverdin and mesobiliverdin in cryptomonad biliproteins. J Biol Chem (1992) 1.04

Alpha helix capping in synthetic model peptides by reciprocal side chain-main chain interactions: evidence for an N terminal "capping box". Proteins (1994) 1.03

Opposing central and peripheral effects of atropine on parasympathetic cardiac control. Am J Physiol (1977) 1.03

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Incorrect aminoacylations involving tRNAs or valyl-tRNA synthetase from Bacillus stearothermophilus. Eur J Biochem (1974) 1.02

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Glutamyl transfer ribonucleic acid synthetase of Escherichia coli. Study of the interactions with its substrates. Biochemistry (1979) 1.00

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The yeast aminoacyl-tRNA synthetases. Methodology for their complete or partial purification and comparison of their relative activities under various extraction conditions. Biochimie (1977) 0.98

Structure of a psoralen cross-linked DNA in solution by nuclear magnetic resonance. Science (1987) 0.97

The monomeric glutamyl-tRNA synthetase of Escherichia coli. Purification and relation between its structural and catalytic properties. J Biol Chem (1979) 0.97

Reassessment of the putative chaperone function of prolyl-cis/trans-isomerases. FEBS Lett (1994) 0.97

A kinetic analysis of the folding of human carbonic anhydrase II and its catalysis by cyclophilin. J Biol Chem (1995) 0.97

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Relative binding affinities of distamycin and its analog to d(CGCAAGTTGGC).d(GCCAACTTGCG): comparison of simulation results with experiment. Proc Natl Acad Sci U S A (1994) 0.96

Chemical shift mapping of the RNA-binding interface of the multiple-RBD protein sex-lethal. Biochemistry (1997) 0.95

Extending the recognition site of designed minor groove binding molecules. Nat Struct Biol (1996) 0.95

Complete purification and studies on the structural and kinetic properties of two forms of yeast valyl-tRNA synthetase. Biochimie (1975) 0.95

Study of the arrangement of the functional domains along the yeast cytoplasmic aspartyl-tRNA synthetase. Eur J Biochem (1989) 0.94

Cytoplasmic aspartyl-tRNA synthetase from Saccharomyces cerevisiae. Study of its functional organisation by deletion analysis. Eur J Biochem (1991) 0.94

Yeast heat shock transcription factor N-terminal activation domains are unstructured as probed by heteronuclear NMR spectroscopy. Protein Sci (1996) 0.93

Solution structure of apamin determined by nuclear magnetic resonance and distance geometry. Biochemistry (1988) 0.93

Localization of needle tip with color doppler during pericardiocentesis: In vitro validation and initial clinical application. J Am Soc Echocardiogr (2001) 0.92

Glycyl-tRNA synthetase from baker's yeast. Interconversion between active and inactive forms of the enzyme. Biochemistry (1981) 0.92

The catalytic mechanism of glutamyl-tRNA synthetase of Escherichia coli. Evidence for a two-step aminoacylation pathway, and study of the reactivity of the intermediate complex. Eur J Biochem (1980) 0.92