Published in Structure on August 12, 2009
Dynamic activation of an allosteric regulatory protein. Nature (2009) 2.61
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Molecular dynamics reveal the essential role of linker motions in the function of cullin-RING E3 ligases. J Mol Biol (2010) 0.85
Dynamic conformational switching in the chemokine ligand is essential for G-protein-coupled receptor activation. Biochem J (2013) 0.85
Conformational sampling and nucleotide-dependent transitions of the GroEL subunit probed by unbiased molecular dynamics simulations. PLoS Comput Biol (2011) 0.84
Rigid Residue Scan Simulations Systematically Reveal Residue Entropic Roles in Protein Allostery. PLoS Comput Biol (2016) 0.84
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Rapid evolutionary dynamics of structural disorder as a potential driving force for biological divergence in flaviviruses. Genome Biol Evol (2013) 0.83
Ensemble properties of network rigidity reveal allosteric mechanisms. Methods Mol Biol (2012) 0.83
Enzyme inhibition by allosteric capture of an inactive conformation. J Mol Biol (2011) 0.83
Specialized Dynamical Properties of Promiscuous Residues Revealed by Simulated Conformational Ensembles. J Chem Theory Comput (2013) 0.83
MCPath: Monte Carlo path generation approach to predict likely allosteric pathways and functional residues. Nucleic Acids Res (2013) 0.83
Allosteric regulation of glycogen synthase kinase 3β: a theoretical study. Biochemistry (2010) 0.83
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Allosteric activation via kinetic control: potassium accelerates a conformational change in IMP dehydrogenase. Biochemistry (2011) 0.82
Allosteric regulation of DegS protease subunits through a shared energy landscape. Nat Chem Biol (2012) 0.82
Positions 94-98 of the lactose repressor N-subdomain monomer-monomer interface are critical for allosteric communication. Biochemistry (2010) 0.82
Local packing modulates diversity of iron pathways and cooperative behavior in eukaryotic and prokaryotic ferritins. J Chem Phys (2014) 0.82
A frustrated binding interface for intrinsically disordered proteins. J Biol Chem (2014) 0.82
"Fluctuograms" reveal the intermittent intra-protein communication in subtilisin Carlsberg and correlate mechanical coupling with co-evolution. PLoS Comput Biol (2011) 0.81
Lysine120 interactions with p53 response elements can allosterically direct p53 organization. PLoS Comput Biol (2010) 0.81
Multiple pathways promote dynamical coupling between catalytic domains in Escherichia coli prolyl-tRNA synthetase. Biochemistry (2013) 0.81
Exploiting conformational dynamics in drug discovery: design of C-terminal inhibitors of Hsp90 with improved activities. J Chem Inf Model (2014) 0.81
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Energy crosstalk between DNA lesions: implications for allosteric coupling of DNA repair and triplet repeat expansion pathways. J Am Chem Soc (2010) 0.80
Comparison of tertiary structures of proteins in protein-protein complexes with unbound forms suggests prevalence of allostery in signalling proteins. BMC Struct Biol (2012) 0.79
Dynamic Allostery Mediated by a Conserved Tryptophan in the Tec Family Kinases. PLoS Comput Biol (2016) 0.79
Modeling allosteric signal propagation using protein structure networks. BMC Bioinformatics (2011) 0.79
Investigating the dynamic aspects of drug-protein recognition through a combination of MD and NMR analyses: implications for the development of protein-protein interaction inhibitors. PLoS One (2014) 0.79
A large-scale allosteric transition in cytochrome P450 3A4 revealed by luminescence resonance energy transfer (LRET). PLoS One (2013) 0.79
Altered backbone and side-chain interactions result in route heterogeneity during the folding of interleukin-1β (IL-1β). Biophys J (2013) 0.79
Molecular Dynamics Simulations Reveal the Mechanisms of Allosteric Activation of Hsp90 by Designed Ligands. Sci Rep (2016) 0.78
Dynamic multiprotein assemblies shape the spatial structure of cell signaling. Prog Biophys Mol Biol (2014) 0.78
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Mismatch binding, ADP-ATP exchange and intramolecular signaling during mismatch repair. DNA Repair (Amst) (2015) 0.78
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A hinge migration mechanism unlocks the evolution of green-to-red photoconversion in GFP-like proteins. Structure (2015) 0.78
Phosphorylation of the retinoic acid receptor alpha induces a mechanical allosteric regulation and changes in internal dynamics. PLoS Comput Biol (2013) 0.78
Molecular dynamics study of naturally existing cavity couplings in proteins. PLoS One (2015) 0.77
DNA-binding protects p53 from interactions with cofactors involved in transcription-independent functions. Nucleic Acids Res (2016) 0.77
Integrating atomistic molecular dynamics simulations, experiments, and network analysis to study protein dynamics: strength in unity. Front Mol Biosci (2015) 0.77
Cyclophilin40 isomerase activity is regulated by a temperature-dependent allosteric interaction with Hsp90. Biosci Rep (2015) 0.77
Allosteric modulators can restore function in an amino acid neurotransmitter receptor by slightly altering intra-molecular communication pathways. Br J Pharmacol (2012) 0.77
Disorder transitions and conformational diversity cooperatively modulate biological function in proteins. Protein Sci (2016) 0.76
Conformational Dynamics and Allostery in Pyruvate Kinase. J Biol Chem (2016) 0.76
Long-Range Signaling in MutS and MSH Homologs via Switching of Dynamic Communication Pathways. PLoS Comput Biol (2016) 0.76
Allosteric activation of Bordetella pertussis adenylyl cyclase by calmodulin: molecular dynamics and mutagenesis studies. J Biol Chem (2014) 0.76
Dancing through Life: Molecular Dynamics Simulations and Network-Centric Modeling of Allosteric Mechanisms in Hsp70 and Hsp110 Chaperone Proteins. PLoS One (2015) 0.76
Conformational diversity analysis reveals three functional mechanisms in proteins. PLoS Comput Biol (2017) 0.76
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