Published in J Cell Biol on February 19, 2001
Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat Cell Biol (2009) 5.44
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Ypt32 recruits the Sec4p guanine nucleotide exchange factor, Sec2p, to secretory vesicles; evidence for a Rab cascade in yeast. J Cell Biol (2002) 3.08
Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes. J Cell Biol (2006) 2.79
Rab27a is required for regulated secretion in cytotoxic T lymphocytes. J Cell Biol (2001) 2.74
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Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice. Proc Natl Acad Sci U S A (2001) 2.00
Vesicles modulate an actin network for asymmetric spindle positioning. Nat Cell Biol (2013) 1.92
Rab27a is an essential component of melanosome receptor for myosin Va. Mol Biol Cell (2002) 1.89
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Complex formation with Ypt11p, a rab-type small GTPase, is essential to facilitate the function of Myo2p, a class V myosin, in mitochondrial distribution in Saccharomyces cerevisiae. Mol Cell Biol (2002) 1.83
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Mmr1p is a mitochondrial factor for Myo2p-dependent inheritance of mitochondria in the budding yeast. EMBO J (2004) 1.53
Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes. J Cell Sci (2004) 1.53
Melanosome maturation defect in Rab38-deficient retinal pigment epithelium results in instability of immature melanosomes during transient melanogenesis. Mol Biol Cell (2007) 1.50
MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes. EMBO Rep (2002) 1.46
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Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites. J Cell Biol (2003) 1.40
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Kinetics of Rab27a-dependent actions on vesicle docking and priming in pancreatic beta-cells. J Physiol (2008) 1.04
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Griscelli syndrome: characterization of a new mutation and rescue of T-cytotoxic activity by retroviral transfer of RAB27A gene. J Clin Immunol (2004) 1.00
Dictyostelium LvsB mutants model the lysosomal defects associated with Chediak-Higashi syndrome. Mol Biol Cell (2002) 0.97
The Rab27a-binding protein, JFC1, regulates androgen-dependent secretion of prostate-specific antigen and prostatic-specific acid phosphatase. Biochem J (2005) 0.95
Rab27b regulates exocytosis of secretory vesicles in acinar epithelial cells from the lacrimal gland. Am J Physiol Cell Physiol (2011) 0.94
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Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion. Elife (2015) 0.92
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Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche. Development (2015) 0.88
Patients with Griscelli syndrome and normal pigmentation identify RAB27A mutations that selectively disrupt MUNC13-4 binding. J Allergy Clin Immunol (2014) 0.87
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Membrane trafficking in osteoblasts and osteoclasts: new avenues for understanding and treating skeletal diseases. Traffic (2012) 0.86
Rab27a is required for human cytomegalovirus assembly. PLoS One (2010) 0.85
Myosin-Va and dynamic actin oppose microtubules to drive long-range organelle transport. Curr Biol (2014) 0.85
Loss of Rab27 function results in abnormal lung epithelium structure in mice. Am J Physiol Cell Physiol (2010) 0.85
A novel statin-mediated "prenylation block-and-release" assay provides insight into the membrane targeting mechanisms of small GTPases. Biochem Biophys Res Commun (2010) 0.84
Rab27a controls HIV-1 assembly by regulating plasma membrane levels of phosphatidylinositol 4,5-bisphosphate. J Cell Biol (2015) 0.83
Rab GTPases, membrane trafficking and diseases. Curr Drug Targets (2011) 0.83
Cortactin promotes exosome secretion by controlling branched actin dynamics. J Cell Biol (2016) 0.83
Regulation of melanosome number, shape and movement in the zebrafish retinal pigment epithelium by OA1 and PMEL. J Cell Sci (2015) 0.82
Normal and abnormal secretion by haemopoietic cells. Immunology (2001) 0.82
An essential role for Rab27a GTPase in eosinophil exocytosis. J Leukoc Biol (2013) 0.82
Role of the small GTPase Rab27a during herpes simplex virus infection of oligodendrocytic cells. BMC Microbiol (2012) 0.82
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NADPH oxidase is internalized by clathrin-coated pits and localizes to a Rab27A/B GTPase-regulated secretory compartment in activated macrophages. J Biol Chem (2011) 0.81
Endo-lysosomal dysfunction in human proximal tubular epithelial cells deficient for lysosomal cystine transporter cystinosin. PLoS One (2015) 0.80
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Melanosomal dynamics assessed with a live-cell fluorescent melanosomal marker. PLoS One (2012) 0.79
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Impaired prenylation of Rab GTPases in the gunmetal mouse causes defects in bone cell function. Small GTPases (2011) 0.78
Interplay between Rab27a effectors in pancreatic β-cells. World J Diabetes (2015) 0.78
Novel 47.5-kb deletion in RAB27A results in severe Griscelli Syndrome Type 2. Mol Genet Metab (2010) 0.78
TPC2 controls pigmentation by regulating melanosome pH and size. Proc Natl Acad Sci U S A (2016) 0.78
Imbalanced Rab3D versus Rab27 increases cathepsin S secretion from lacrimal acini in a mouse model of Sjögren's Syndrome. Am J Physiol Cell Physiol (2016) 0.76
Anti-cancer effects of nitrogen-containing bisphosphonates on human cancer cells. Oncotarget (2016) 0.75
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Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes. Nat Commun (2016) 0.75
Myosin Va's adaptor protein melanophilin enforces track selection on the microtubule and actin networks in vitro. Proc Natl Acad Sci U S A (2017) 0.75
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