Published in Curr Opin Cell Biol on December 01, 2009
The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis. Nat Rev Mol Cell Biol (2012) 2.99
Sensing centromere tension: Aurora B and the regulation of kinetochore function. Trends Cell Biol (2010) 2.88
Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesis. Sci Signal (2010) 2.79
Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase. J Cell Biol (2010) 2.51
Cancer chromosomal instability: therapeutic and diagnostic challenges. EMBO Rep (2012) 2.28
Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell (2017) 2.02
Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction. EMBO J (2011) 1.62
Merotelic kinetochore attachment: causes and effects. Trends Cell Biol (2011) 1.60
The CCAN recruits CENP-A to the centromere and forms the structural core for kinetochore assembly. J Cell Biol (2012) 1.50
Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation. J Cell Biol (2011) 1.35
Drugging MYCN through an allosteric transition in Aurora kinase A. Cancer Cell (2014) 1.33
Aurora kinase inhibitors as anticancer molecules. Biochim Biophys Acta (2010) 1.33
The chromosomal passenger complex activates Polo kinase at centromeres. PLoS Biol (2012) 1.33
Kinetochore-microtubule interactions: steps towards bi-orientation. EMBO J (2010) 1.30
Bub1 and BubR1: at the interface between chromosome attachment and the spindle checkpoint. Mol Cell Biol (2011) 1.29
The chromosomal passenger complex and centralspindlin independently contribute to contractile ring assembly. J Cell Biol (2011) 1.26
Understanding the Polo Kinase machine. Oncogene (2015) 1.23
Orchestrating vesicle transport, ESCRTs and kinase surveillance during abscission. Nat Rev Mol Cell Biol (2012) 1.21
Centrosomal protein of 192 kDa (Cep192) promotes centrosome-driven spindle assembly by engaging in organelle-specific Aurora A activation. Proc Natl Acad Sci U S A (2010) 1.17
p53 negatively regulates Aurora A via both transcriptional and posttranslational regulation. Cell Cycle (2012) 1.15
Arabidopsis α Aurora kinases function in formative cell division plane orientation. Plant Cell (2011) 1.14
Calmodulin activation of Aurora-A kinase (AURKA) is required during ciliary disassembly and in mitosis. Mol Biol Cell (2012) 1.13
Phosphorylation at serine 331 is required for Aurora B activation. J Cell Biol (2011) 1.10
Aurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindle. Open Biol (2013) 1.09
Control of Aurora-A stability through interaction with TPX2. J Cell Sci (2010) 1.09
Diversity, classification and function of the plant protein kinase superfamily. Philos Trans R Soc Lond B Biol Sci (2012) 1.08
Mitotic spindle proteomics in Chinese hamster ovary cells. PLoS One (2011) 1.08
Cell cycle regulation of Greatwall kinase nuclear localization facilitates mitotic progression. J Cell Biol (2013) 1.08
Dynein at the kinetochore: Timing, Interactions and Functions. Semin Cell Dev Biol (2010) 1.07
Binucleine 2, an isoform-specific inhibitor of Drosophila Aurora B kinase, provides insights into the mechanism of cytokinesis. ACS Chem Biol (2010) 1.05
Plk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis. Mol Biol Cell (2012) 1.05
Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells. J Cell Biol (2012) 1.03
Mitotic Stress and Chromosomal Instability in Cancer: The Case for TPX2. Genes Cancer (2012) 1.02
PP2A-twins is antagonized by greatwall and collaborates with polo for cell cycle progression and centrosome attachment to nuclei in drosophila embryos. PLoS Genet (2011) 1.02
Cell cycle progression by the repression of primary cilia formation in proliferating cells. Cell Mol Life Sci (2013) 0.99
c-Src but not Fyn promotes proper spindle orientation in early prometaphase. J Biol Chem (2012) 0.98
Ipl1/Aurora-dependent phosphorylation of Sli15/INCENP regulates CPC-spindle interaction to ensure proper microtubule dynamics. J Cell Biol (2011) 0.97
Molecular targeted agents for gastric and gastroesophageal junction cancer. Surg Today (2011) 0.97
Gradient of increasing Aurora B kinase activity is required for cells to execute mitosis. J Biol Chem (2010) 0.96
Xenopus Shugoshin 2 regulates the spindle assembly pathway mediated by the chromosomal passenger complex. EMBO J (2012) 0.95
Mitotic catastrophe and cell death induced by depletion of centrosomal proteins. Cell Death Dis (2013) 0.95
Condensin and the spindle midzone prevent cytokinesis failure induced by chromatin bridges in C. elegans embryos. Curr Biol (2013) 0.95
Polo-like kinase-activating kinases: Aurora A, Aurora B and what else? Cell Cycle (2012) 0.94
Regulation of the cell division cycle in Trypanosoma brucei. Eukaryot Cell (2012) 0.94
Aurora B hyperactivation by Bub1 overexpression promotes chromosome missegregation. Cell Cycle (2011) 0.94
Aurora A orchestrates entosis by regulating a dynamic MCAK-TIP150 interaction. J Mol Cell Biol (2014) 0.93
WNK1 is required for mitosis and abscission. Proc Natl Acad Sci U S A (2011) 0.91
Drosophila Ajuba is not an Aurora-A activator but is required to maintain Aurora-A at the centrosome. J Cell Sci (2011) 0.91
A functional cooperativity between Aurora A kinase and LIM kinase1: implication in the mitotic process. Cell Cycle (2012) 0.91
Aurora B-dependent regulation of class IIa histone deacetylases by mitotic nuclear localization signal phosphorylation. Mol Cell Proteomics (2012) 0.91
Zwint-1 is a novel Aurora B substrate required for the assembly of a dynein-binding platform on kinetochores. Mol Biol Cell (2011) 0.91
PI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3γ and is required for metaphase-anaphase transition. Nat Commun (2013) 0.90
Aurora kinases phosphorylate Lgl to induce mitotic spindle orientation in Drosophila epithelia. Curr Biol (2014) 0.90
Aurora B is regulated by acetylation/deacetylation during mitosis in prostate cancer cells. FASEB J (2012) 0.89
Regulation of APC/CCdc20 activity by RASSF1A-APC/CCdc20 circuitry. Oncogene (2011) 0.88
The novel function of JADE1S in cytokinesis of epithelial cells. Cell Cycle (2015) 0.88
Coordinating cell polarity and cell cycle progression: what can we learn from flies and worms? Open Biol (2013) 0.87
Chromatin protein HP1 interacts with the mitotic regulator borealin protein and specifies the centromere localization of the chromosomal passenger complex. J Biol Chem (2014) 0.87
Aurora A phosphorylation of WD40-repeat protein 62 in mitotic spindle regulation. Cell Cycle (2016) 0.86
Abscission checkpoint control: stuck in the middle with Aurora B. Open Biol (2012) 0.86
Aurora-A Kinase as a Promising Therapeutic Target in Cancer. Front Oncol (2016) 0.86
A role for p38 in transcriptional elongation of p21 (CIP1) in response to Aurora B inhibition. Cell Cycle (2013) 0.85
Identification of aurora kinase B and Wee1-like protein kinase as downstream targets of (V600E)B-RAF in melanoma. Am J Pathol (2013) 0.85
Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis. Biochem J (2010) 0.85
A novel role for TPX2 as a scaffold and co-activator protein of the Chromosomal Passenger Complex. Cell Signal (2012) 0.84
Protein tyrosine phosphatase Shp2 (Ptpn11) plays an important role in maintenance of chromosome stability. Cancer Res (2012) 0.83
Regulatory dephosphorylation of CDK at G₂/M in plants: yeast mitotic phosphatase cdc25 induces cytokinin-like effects in transgenic tobacco morphogenesis. Ann Bot (2011) 0.83
Protein Kinase Activity Decreases with Higher Braak Stages of Alzheimer's Disease Pathology. J Alzheimers Dis (2015) 0.83
Rho GTPase-independent regulation of mitotic progression by the RhoGEF Net1. Mol Biol Cell (2013) 0.82
Basal aurora kinase B activity is sufficient for histone H3 phosphorylation in prophase. Biol Open (2013) 0.82
Spatial Compartmentalization Specializes the Function of Aurora A and Aurora B. J Biol Chem (2015) 0.81
Current and future trials of targeted therapies in cutaneous melanoma. Adv Exp Med Biol (2013) 0.81
Targeted therapies for advanced Ewing sarcoma family of tumors. Cancer Treat Rev (2015) 0.81
Kif2a depletion generates chromosome segregation and pole coalescence defects in animal caps and inhibits gastrulation of the Xenopus embryo. Mol Biol Cell (2015) 0.80
A Cell Biologist's Field Guide to Aurora Kinase Inhibitors. Front Oncol (2015) 0.80
Aurora B Overexpression Causes Aneuploidy and p21Cip1 Repression during Tumor Development. Mol Cell Biol (2015) 0.80
Loss of Survivin influences liver regeneration and is associated with impaired Aurora B function. Cell Death Differ (2013) 0.79
Polo kinase regulates the localization and activity of the chromosomal passenger complex in meiosis and mitosis in Drosophila melanogaster. Open Biol (2014) 0.78
Translation of incenp during oocyte maturation is required for embryonic development in Xenopus laevis. Biol Reprod (2012) 0.78
Differentially expressed epigenome modifiers, including aurora kinases A and B, in immune cells in rheumatoid arthritis in humans and mouse models. Arthritis Rheum (2013) 0.78
Mitotic Kinases and p53 Signaling. Biochem Res Int (2012) 0.78
RNA interference-mediated knockdown of Aurora-B alters the metastatic behavior of A549 cells via modulation of the phosphoinositide 3-kinase/Akt signaling pathway. Oncol Lett (2014) 0.78
STK31 is a cell-cycle regulated protein that contributes to the tumorigenicity of epithelial cancer cells. PLoS One (2014) 0.78
The Dawn of Aurora Kinase Research: From Fly Genetics to the Clinic. Front Cell Dev Biol (2015) 0.77
Aurora kinase a regulates m1 macrophage polarization and plays a role in experimental autoimmune encephalomyelitis. Inflammation (2015) 0.77
Dynamical scenarios for chromosome bi-orientation. Biophys J (2013) 0.77
Urochordate ascidians possess a single isoform of Aurora kinase that localizes to the midbody via TPX2 in eggs and cleavage stage embryos. PLoS One (2012) 0.77
Multiplex imaging and cellular target identification of kinase inhibitors via an affinity-based proteome profiling approach. Sci Rep (2015) 0.77
Ku70 Serine 155 mediates Aurora B inhibition and activation of the DNA damage response. Sci Rep (2016) 0.77
Efficient prediction of human protein-protein interactions at a global scale. BMC Bioinformatics (2014) 0.77
New insights into the molecular mechanisms of mitosis and cytokinesis in trypanosomes. Int Rev Cell Mol Biol (2014) 0.77
In vitro high throughput screening, what next? Lessons from the screening for aurora kinase inhibitors. Biology (Basel) (2014) 0.77
Kalanchoe tubiflora extract inhibits cell proliferation by affecting the mitotic apparatus. BMC Complement Altern Med (2012) 0.76
Mio depletion links mTOR regulation to Aurora A and Plk1 activation at mitotic centrosomes. J Cell Biol (2015) 0.76
Ubiquitin-Mediated Degradation of Aurora Kinases. Front Oncol (2016) 0.76
A role for plant AURORA kinases in formative cell division. Plant Cell (2011) 0.76
Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex. PLoS One (2016) 0.76
Small molecule inhibitors in acute myeloid leukemia: from the bench to the clinic. Expert Rev Hematol (2014) 0.76
Aurora A inhibition by MNL8054 promotes centriole elongation during Drosophila male meiosis. Cell Cycle (2015) 0.75
Function following form: functional differentiation of mammary epithelial cells requires laminin-induced polarization of PI3-kinase. Cell Cycle (2011) 0.75
Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores. J Cell Biol (2003) 9.27
The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cell (2006) 8.44
The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint. J Cell Biol (2003) 8.32
A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers. EMBO J (1998) 7.39
Chromosomal passengers: conducting cell division. Nat Rev Mol Cell Biol (2007) 6.83
Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections. Cell (2002) 6.59
HEF1-dependent Aurora A activation induces disassembly of the primary cilium. Cell (2007) 6.50
Kinetochore microtubule dynamics and attachment stability are regulated by Hec1. Cell (2006) 6.46
The cellular geography of aurora kinases. Nat Rev Mol Cell Biol (2003) 6.40
Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells. Cell (2003) 5.68
Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles. Cell (1995) 5.56
Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity. Dev Cell (2002) 5.52
Aurora B-mediated abscission checkpoint protects against tetraploidization. Cell (2009) 5.26
Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase. Cell (2000) 5.10
Aurora B regulates MCAK at the mitotic centromere. Dev Cell (2004) 4.94
The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint. Genes Dev (2001) 4.82
The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks. Nature (2005) 4.63
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle. Mol Cell (2003) 4.51
Essential roles of Drosophila inner centromere protein (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation. J Cell Biol (2001) 4.38
Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery. Nature (2008) 4.33
Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis. Mol Biol Cell (2003) 4.28
Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype. Curr Biol (2000) 4.27
Shugoshin collaborates with protein phosphatase 2A to protect cohesin. Nature (2006) 4.23
Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity. Curr Biol (2004) 4.20
Genome stability is ensured by temporal control of kinetochore-microtubule dynamics. Nat Cell Biol (2008) 4.15
Sensing chromosome bi-orientation by spatial separation of aurora B kinase from kinetochore substrates. Science (2009) 4.10
The inner centromere protein (INCENP) antigens: movement from inner centromere to midbody during mitosis. J Cell Biol (1987) 4.05
Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together. Cell (2007) 3.98
PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation. Dev Cell (2006) 3.88
Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans. J Cell Biol (2001) 3.86
Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry. Science (2008) 3.77
Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient. Nature (2008) 3.77
AIM-1: a mammalian midbody-associated protein required for cytokinesis. EMBO J (1998) 3.73
Human TPX2 is required for targeting Aurora-A kinase to the spindle. J Cell Biol (2002) 3.69
The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly. Cell (2004) 3.68
The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase. Mol Cell (2002) 3.65
INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow. Curr Biol (2000) 3.55
Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle. J Cell Biol (2004) 3.49
The NoCut pathway links completion of cytokinesis to spindle midzone function to prevent chromosome breakage. Cell (2006) 3.45
Mps1 phosphorylates Borealin to control Aurora B activity and chromosome alignment. Cell (2008) 3.38
Initiation and growth of microtubules from mitotic centers in lysed mammalian cells. J Cell Biol (1975) 3.36
Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments. Mol Biol Cell (2003) 3.30
The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments. Nat Cell Biol (2004) 3.27
Aurora-A: the maker and breaker of spindle poles. J Cell Sci (2007) 3.20
Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis. Curr Biol (2002) 3.17
A microtubule-dependent zone of active RhoA during cleavage plane specification. J Cell Biol (2005) 3.15
Mechanism of Aurora B activation by INCENP and inhibition by hesperadin. Mol Cell (2005) 3.14
Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules. J Cell Biol (2002) 3.05
TPX2, A novel xenopus MAP involved in spindle pole organization. J Cell Biol (2000) 3.01
Chromosomal passengers: the four-dimensional regulation of mitotic events. Chromosoma (2004) 2.94
Chk1 is required for spindle checkpoint function. Dev Cell (2007) 2.90
The Aurora kinase family in cell division and cancer. Biochim Biophys Acta (2008) 2.84
Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast. Genetics (1993) 2.82
Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis. Genes Dev (2002) 2.77
HURP is part of a Ran-dependent complex involved in spindle formation. Curr Biol (2006) 2.74
Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension. EMBO J (2003) 2.70
A novel mechanism for activation of the protein kinase Aurora A. Curr Biol (2003) 2.68
Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells. Mol Cell (2004) 2.64
INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis. Curr Biol (2001) 2.62
Mitotic activation of the kinase Aurora-A requires its binding partner Bora. Dev Cell (2006) 2.57
Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation. Mol Biol Cell (2002) 2.56
Phosphorylation by aurora B converts MgcRacGAP to a RhoGAP during cytokinesis. Dev Cell (2003) 2.54
Human Bub1 defines the persistent cohesion site along the mitotic chromosome by affecting Shugoshin localization. Curr Biol (2005) 2.53
Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit. Genes Dev (2002) 2.51
Differentiation of cytoplasmic and meiotic spindle assembly MCAK functions by Aurora B-dependent phosphorylation. Mol Biol Cell (2004) 2.51
Survivin is required for stable checkpoint activation in taxol-treated HeLa cells. J Cell Sci (2003) 2.48
Cell cycle kinases in cancer. Curr Opin Genet Dev (2007) 2.46
Phosphorylation of the carboxyl terminus of inner centromere protein (INCENP) by the Aurora B Kinase stimulates Aurora B kinase activity. J Biol Chem (2002) 2.40
Telophase disc: a new mammalian mitotic organelle that bisects telophase cells with a possible function in cytokinesis. J Cell Sci (1991) 2.32
Centromeric Aurora-B activation requires TD-60, microtubules, and substrate priming phosphorylation. Science (2008) 2.28
Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly. Dev Cell (2007) 2.25
APC/C Cdh1 targets aurora kinase to control reorganization of the mitotic spindle at anaphase. Curr Biol (2008) 2.18
Regulation of sister chromatid cohesion between chromosome arms. Curr Biol (2004) 2.16
The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A. Mol Cell (2005) 2.11
The mammalian passenger protein TD-60 is an RCC1 family member with an essential role in prometaphase to metaphase progression. Dev Cell (2003) 2.08
A mechanism for chromosome segregation sensing by the NoCut checkpoint. Nat Cell Biol (2009) 2.04
A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells. Dev Cell (2007) 1.98
Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition. J Cell Sci (2004) 1.93
Polo and Aurora kinases: lessons derived from chemical biology. Curr Opin Cell Biol (2008) 1.92
Regulation of mitotic chromosome cohesion by Haspin and Aurora B. Dev Cell (2006) 1.89
Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody. EMBO Rep (2006) 1.82
Condensin regulates the stiffness of vertebrate centromeres. Mol Biol Cell (2009) 1.81
Sister chromatid tension and the spindle assembly checkpoint. Curr Opin Cell Biol (2009) 1.80
NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment. Mol Cell Biol (2006) 1.69
Aurora B phosphorylates multiple sites on mitotic centromere-associated kinesin to spatially and temporally regulate its function. Mol Biol Cell (2007) 1.66
Plk1 regulates mitotic Aurora A function through betaTrCP-dependent degradation of hBora. Chromosoma (2008) 1.60
Cell cycle-dependent expression and centrosome localization of a third human aurora/Ipl1-related protein kinase, AIK3. J Biol Chem (1999) 1.59
Regulation of Xenopus Aurora A activation by TPX2. J Biol Chem (2003) 1.58
Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line. J Cell Biol (2008) 1.54
Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization. J Cell Biol (2008) 1.53
Aurora A kinase-coated beads function as microtubule-organizing centers and enhance RanGTP-induced spindle assembly. Curr Biol (2005) 1.52
Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein. Proc Natl Acad Sci U S A (2004) 1.51
Glc7/protein phosphatase 1 regulatory subunits can oppose the Ipl1/aurora protein kinase by redistributing Glc7. Mol Cell Biol (2006) 1.50
Aurora A phosphorylates MCAK to control ran-dependent spindle bipolarity. Mol Biol Cell (2008) 1.49
Aurora B is required for mitotic chromatin-induced phosphorylation of Op18/Stathmin. Proc Natl Acad Sci U S A (2006) 1.43
Dynamic localization and functional implications of Aurora-C kinase during male mouse meiosis. Dev Biol (2006) 1.43
Aurora-B associated protein phosphatases as negative regulators of kinase activation. Oncogene (2002) 1.37
The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase. Genes Cells (2004) 1.35
Aurora A regulates the activity of HURP by controlling the accessibility of its microtubule-binding domain. Mol Biol Cell (2008) 1.35
Survivin enhances Aurora-B kinase activity and localizes Aurora-B in human cells. J Biol Chem (2002) 1.35
Chromosomal passengers: conducting cell division. Nat Rev Mol Cell Biol (2007) 6.83
The cellular geography of aurora kinases. Nat Rev Mol Cell Biol (2003) 6.40
Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell (2003) 4.13
The dynamic kinetochore-microtubule interface. J Cell Sci (2004) 4.07
Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle. J Cell Biol (2004) 3.49
The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics. Cell (2010) 3.26
Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling. Nat Genet (2007) 3.08
The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis. Nat Rev Mol Cell Biol (2012) 2.99
Chromosomal passengers: the four-dimensional regulation of mitotic events. Chromosoma (2004) 2.94
Chk1 is required for spindle checkpoint function. Dev Cell (2007) 2.90
Condensin is required for nonhistone protein assembly and structural integrity of vertebrate mitotic chromosomes. Dev Cell (2003) 2.62
Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation. EMBO J (2004) 2.60
Inactivation of a human kinetochore by specific targeting of chromatin modifiers. Dev Cell (2008) 2.50
Survivin is required for stable checkpoint activation in taxol-treated HeLa cells. J Cell Sci (2003) 2.48
A super-resolution map of the vertebrate kinetochore. Proc Natl Acad Sci U S A (2010) 2.36
Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics. Cell (2003) 2.20
Trashing the genome: the role of nucleases during apoptosis. Nat Rev Mol Cell Biol (2005) 2.19
Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore. EMBO J (2010) 2.17
Condensin and Repo-Man-PP1 co-operate in the regulation of chromosome architecture during mitosis. Nat Cell Biol (2006) 2.16
Mitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIα. J Cell Biol (2012) 1.94
CENP-I is essential for centromere function in vertebrate cells. Dev Cell (2002) 1.94
Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM. EMBO J (2004) 1.89
Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation. EMBO J (2002) 1.82
Condensin regulates the stiffness of vertebrate centromeres. Mol Biol Cell (2009) 1.81
MAST/Orbit has a role in microtubule-kinetochore attachment and is essential for chromosome alignment and maintenance of spindle bipolarity. J Cell Biol (2002) 1.81
INCENP and Aurora B promote meiotic sister chromatid cohesion through localization of the Shugoshin MEI-S332 in Drosophila. Dev Cell (2006) 1.71
Condensin: Architect of mitotic chromosomes. Chromosome Res (2009) 1.67
Kinetochore localisation of the DNA damage response component 53BP1 during mitosis. J Cell Sci (2002) 1.61
Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells. Cell Motil Cytoskeleton (2004) 1.59
Co-localization of centromere activity, proteins and topoisomerase II within a subdomain of the major human X alpha-satellite array. EMBO J (2002) 1.58
Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line. J Cell Biol (2008) 1.54
Condensin I interacts with the PARP-1-XRCC1 complex and functions in DNA single-strand break repair. Mol Cell (2006) 1.54
Aurora-B phosphorylation in vitro identifies a residue of survivin that is essential for its localization and binding to inner centromere protein (INCENP) in vivo. J Biol Chem (2003) 1.50
Repo-Man coordinates chromosomal reorganization with nuclear envelope reassembly during mitotic exit. Dev Cell (2011) 1.43
Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly. EMBO J (2012) 1.41
Contrasting roles of condensin I and condensin II in mitotic chromosome formation. J Cell Sci (2012) 1.35
The chromosomal passenger complex activates Polo kinase at centromeres. PLoS Biol (2012) 1.33
Chromosome engineering allows the efficient isolation of vertebrate neocentromeres. Dev Cell (2013) 1.30
Sgt1 is required for human kinetochore assembly. EMBO Rep (2004) 1.30
Human artificial chromosome with a conditional centromere for gene delivery and gene expression. DNA Res (2010) 1.29
Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function. Mol Biol Cell (2006) 1.26
Human artificial chromosome-based gene delivery vectors for biomedicine and biotechnology. Expert Opin Drug Deliv (2014) 1.26
CENP-C binds the alpha-satellite DNA in vivo at specific centromere domains. J Cell Sci (2002) 1.25
INCENP-aurora B interactions modulate kinase activity and chromosome passenger complex localization. J Cell Biol (2009) 1.23
The chromosomal passenger complex: one for all and all for one. Cell (2007) 1.22
Human artificial chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cells. Proc Natl Acad Sci U S A (2011) 1.21
RNAi analysis reveals an unexpected role for topoisomerase II in chromosome arm congression to a metaphase plate. J Cell Sci (2003) 1.20
Efficiency of de novo centromere formation in human artificial chromosomes. Genomics (2002) 1.19
Hierarchical inactivation of a synthetic human kinetochore by a chromatin modifier. Mol Biol Cell (2009) 1.19
Proteomic analysis of human metaphase chromosomes reveals topoisomerase II alpha as an Aurora B substrate. Nucleic Acids Res (2002) 1.15
In vivo functional dissection of human inner kinetochore protein CENP-C. J Struct Biol (2002) 1.14
Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking sister kinetochores. EMBO Rep (2004) 1.11
Dual roles of Incenp crucial to the assembly of the acentrosomal metaphase spindle in female meiosis. Development (2008) 1.10
Three distinct stages of apoptotic nuclear condensation revealed by time-lapse imaging, biochemical and electron microscopy analysis of cell-free apoptosis. Exp Cell Res (2007) 1.10
SUMOylation modulates the function of Aurora-B kinase. J Cell Sci (2010) 1.10
Reverse genetics of essential genes in tissue-culture cells: 'dead cells talking'. Trends Cell Biol (2002) 1.10
Mitotic chromosome formation and the condensin paradox. Exp Cell Res (2004) 1.07
A new generation of human artificial chromosomes for functional genomics and gene therapy. Cell Mol Life Sci (2012) 1.06
Novel components of human mitotic chromosomes identified by proteomic analysis of the chromosome scaffold fraction. Chromosoma (2004) 1.06
Molecular and genetic analysis of condensin function in vertebrate cells. Mol Biol Cell (2008) 1.06
Vascular smooth muscle cell polyploidization involves changes in chromosome passenger proteins and an endomitotic cell cycle. Exp Cell Res (2005) 1.05
Epigenetic engineering: histone H3K9 acetylation is compatible with kinetochore structure and function. J Cell Sci (2012) 1.03
Condensin I associates with structural and gene regulatory regions in vertebrate chromosomes. Nat Commun (2013) 1.02
HACking the centromere chromatin code: insights from human artificial chromosomes. Chromosome Res (2012) 1.02
A promoter-hijack strategy for conditional shutdown of multiply spliced essential cell cycle genes. Proc Natl Acad Sci U S A (2008) 1.01
Organization of synthetic alphoid DNA array in human artificial chromosome (HAC) with a conditional centromere. ACS Synth Biol (2012) 0.99
Dynamic relocalization of the chromosomal passenger complex proteins inner centromere protein (INCENP) and aurora-B kinase during male mouse meiosis. J Cell Sci (2003) 0.99
Apoptosis-associated caspase activation assays. Methods (2008) 0.98
Gradient of increasing Aurora B kinase activity is required for cells to execute mitosis. J Biol Chem (2010) 0.96
Building mitotic chromosomes. Curr Opin Cell Biol (2010) 0.95
How do kinetochores CLASP dynamic microtubules? Cell Cycle (2003) 0.94
Super-resolution fluorescence microscopy as a tool to study the nanoscale organization of chromosomes. Curr Opin Chem Biol (2011) 0.93
A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells. BMC Cancer (2013) 0.92
Lack of correlation between caspase activation and caspase activity assays in paclitaxel-treated MCF-7 breast cancer cells. J Biol Chem (2001) 0.91
CENP-V is required for centromere organization, chromosome alignment and cytokinesis. EMBO J (2008) 0.91
Caspase-7 gene disruption reveals an involvement of the enzyme during the early stages of apoptosis. J Biol Chem (2003) 0.89
Genetic analysis of the short splice variant of the inhibitor of caspase-activated DNase (ICAD-S) in chicken DT40 cells. J Biol Chem (2007) 0.85
Repo-Man-PP1: a link between chromatin remodelling and nuclear envelope reassembly. Nucleus (2012) 0.85
Protecting a transgene expression from the HAC-based vector by different chromatin insulators. Cell Mol Life Sci (2013) 0.82
Nap1 regulates proper CENP-B binding to nucleosomes. Nucleic Acids Res (2013) 0.82
INCENP at the kinase crossroads. Nat Cell Biol (2006) 0.82
Shugoshin: a centromeric guardian senses tension. Bioessays (2005) 0.81
Drosophila Incenp is required for cytokinesis and asymmetric cell division during development of the nervous system. J Cell Sci (2006) 0.81
Acetylation of core histones in response to HDAC inhibitors is diminished in mitotic HeLa cells. Exp Cell Res (2010) 0.80
Re-engineering an alphoid(tetO)-HAC-based vector to enable high-throughput analyses of gene function. Nucleic Acids Res (2013) 0.80
Death receptor-induced apoptosis reveals a novel interplay between the chromosomal passenger complex and CENP-C during interphase. Mol Biol Cell (2007) 0.80
Effects of full-length borealin on the composition and protein-protein interaction activity of a binary chromosomal passenger complex. Biochemistry (2009) 0.79
DNA content of a functioning chicken kinetochore. Chromosome Res (2014) 0.78
Genetic analysis of apoptotic execution. Subcell Biochem (2006) 0.78